IT1224546B - Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative - Google Patents

Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative

Info

Publication number
IT1224546B
IT1224546B IT8848398A IT4839888A IT1224546B IT 1224546 B IT1224546 B IT 1224546B IT 8848398 A IT8848398 A IT 8848398A IT 4839888 A IT4839888 A IT 4839888A IT 1224546 B IT1224546 B IT 1224546B
Authority
IT
Italy
Prior art keywords
indolpiruvic
acid
agent inhibitor
degenerative pathologies
pharmaceutical user
Prior art date
Application number
IT8848398A
Other languages
English (en)
Other versions
IT8848398A0 (it
Inventor
Politi Vincenzo
De Luca Giovanna
Di Stazio Giovanni
Materazzi Mario
Original Assignee
Polifarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polifarma Spa filed Critical Polifarma Spa
Priority to IT8848398A priority Critical patent/IT1224546B/it
Publication of IT8848398A0 publication Critical patent/IT8848398A0/it
Priority to US07/394,861 priority patent/US5075329A/en
Priority to EP19890830378 priority patent/EP0362152A3/en
Priority to JP1253706A priority patent/JPH02129121A/ja
Application granted granted Critical
Publication of IT1224546B publication Critical patent/IT1224546B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IT8848398A 1988-09-29 1988-09-29 Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative IT1224546B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT8848398A IT1224546B (it) 1988-09-29 1988-09-29 Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative
US07/394,861 US5075329A (en) 1988-09-29 1989-08-17 Use of 3-indolepyruvic acid as a pharmaceutical agent for the inhibition of peripheral degenerative pathologies
EP19890830378 EP0362152A3 (en) 1988-09-29 1989-09-06 Use of 3-indolepyruvic acid as a pharmaceutical agent for the inhibition of peripheral degenerative pathologies
JP1253706A JPH02129121A (ja) 1988-09-29 1989-09-28 未梢変性疾患治療剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8848398A IT1224546B (it) 1988-09-29 1988-09-29 Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative

Publications (2)

Publication Number Publication Date
IT8848398A0 IT8848398A0 (it) 1988-09-29
IT1224546B true IT1224546B (it) 1990-10-04

Family

ID=11266321

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848398A IT1224546B (it) 1988-09-29 1988-09-29 Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative

Country Status (4)

Country Link
US (1) US5075329A (it)
EP (1) EP0362152A3 (it)
JP (1) JPH02129121A (it)
IT (1) IT1224546B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232167B (it) * 1989-08-08 1992-01-25 Polifarma Spa Uso cosmetico di acido 3-indolpiruvico
IT1261165B (it) * 1993-01-25 1996-05-09 Polifarma Spa Agente attivo per ridurre il livello ematico di glucocorticoidi e prevenire disturbi cerebrali da stress e senilita'.
JP6544827B2 (ja) * 2015-09-10 2019-07-17 国立研究開発法人農業・食品産業技術総合研究機構 腸疾患の予防剤および／または治療剤
WO2020012373A1 (en) * 2018-07-10 2020-01-16 Polindols S.R.L.S. New drugs chronic invalidating pathologies and to slow aging, based on a new metabolic tryptophan route and production process thereof
CN115813919B (zh) * 2022-12-08 2024-02-06 佛山市妇幼保健院 吲哚-3-丙酮酸或其药用盐在制备治疗乳腺癌药物中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5120560A (en) * 1974-07-31 1976-02-18 Matsushita Electric Industrial Co Ltd Suitsuchi
IT1148618B (it) * 1982-10-11 1986-12-03 Polifarma Spa Procedimento enzimatico per la produzione di acido 3-indolpiruvico e utilizzazione farmaceutica di questo
JPS61501567A (ja) * 1984-03-01 1986-07-31 ア−ク，バ−ノン 動脈硬化の予防および治療方法
JPS61100565A (ja) * 1984-10-22 1986-05-19 Green Cross Corp:The インド−ル酢酸誘導体
IT1184282B (it) * 1985-06-28 1987-10-22 Polifarma Spa Procedimento per la produzione di alfa-chetoacidi indolici a partire da un rispettivo alfa-ammino-acido,particolarmente per produrre acido indolpiruvico
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico

Also Published As

Publication number Publication date
EP0362152A3 (en) 1991-04-03
JPH02129121A (ja) 1990-05-17
US5075329A (en) 1991-12-24
EP0362152A2 (en) 1990-04-04
IT8848398A0 (it) 1988-09-29

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