IT1227916B - Mezzo di perfusione per la preservazione di organi - Google Patents

Mezzo di perfusione per la preservazione di organi

Info

Publication number
IT1227916B
IT1227916B IT8823136A IT2313688A IT1227916B IT 1227916 B IT1227916 B IT 1227916B IT 8823136 A IT8823136 A IT 8823136A IT 2313688 A IT2313688 A IT 2313688A IT 1227916 B IT1227916 B IT 1227916B
Authority
IT
Italy
Prior art keywords
preservation
bodies
perfusion means
perfusion
Prior art date
Application number
IT8823136A
Other languages
English (en)
Other versions
IT8823136A0 (it
Inventor
Folkert O Belzer
James H Southard
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IT8823136A0 publication Critical patent/IT8823136A0/it
Application granted granted Critical
Publication of IT1227916B publication Critical patent/IT1227916B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT8823136A 1987-12-29 1988-12-28 Mezzo di perfusione per la preservazione di organi IT1227916B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/139,530 US4879283A (en) 1985-10-03 1987-12-29 Solution for the preservation of organs

Publications (2)

Publication Number Publication Date
IT8823136A0 IT8823136A0 (it) 1988-12-28
IT1227916B true IT1227916B (it) 1991-05-14

Family

ID=22487110

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8823136A IT1227916B (it) 1987-12-29 1988-12-28 Mezzo di perfusione per la preservazione di organi

Country Status (17)

Country Link
US (1) US4879283A (it)
JP (1) JPH0768082B2 (it)
KR (1) KR950015064B1 (it)
AU (1) AU609236B2 (it)
BE (1) BE1003362A3 (it)
CH (1) CH678912A5 (it)
DE (1) DE3843958C2 (it)
FR (1) FR2625073B1 (it)
GB (1) GB2213362B (it)
HU (1) HU200885B (it)
IT (1) IT1227916B (it)
NL (1) NL193971C (it)
NZ (1) NZ227516A (it)
PH (1) PH27182A (it)
RU (1) RU2019965C1 (it)
SE (1) SE503182C2 (it)
ZA (1) ZA889683B (it)

Families Citing this family (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0822801B2 (ja) * 1989-10-06 1996-03-06 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 臓器保存用溶液
US5082831A (en) * 1989-12-05 1992-01-21 Cryovita Laboratories, Inc. Total body washout solution and method of use
US5145771A (en) * 1990-04-12 1992-09-08 The University Of North Carolina At Chapel Hill Rinse solution for organs and tissues
WO1992003046A1 (en) * 1990-08-28 1992-03-05 Somatix Therapy Corporation Improved cell cryopreservation method
GB9021325D0 (en) * 1990-10-01 1990-11-14 Geistlich Soehne Ag Chemical composition
CH683485A5 (fr) * 1990-11-20 1994-03-31 Pasteur Merieux Serums Vacc Solutions de perfusion, de conservation et de reperfusion d'organes.
US5704297A (en) * 1991-02-06 1998-01-06 The Dupont Merck Pharmaceutical Company Dry powder composition of hydroxyethyl starch suitable for reconstitution
US5723282A (en) * 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
DE4122999A1 (de) * 1991-07-11 1993-01-14 Laevosan Gmbh & Co Kg Metabolisierbarer plasmaersatz
US5200398A (en) * 1991-09-12 1993-04-06 Mount Sinai Hospital Corporation Composition for the preservation of organs comprising glucuronic acid or a physiologically tolerated salt or ester thereof
US5328821A (en) * 1991-12-12 1994-07-12 Robyn Fisher Cold and cryo-preservation methods for human tissue slices
RU2025973C1 (ru) * 1992-02-10 1995-01-09 Научно-производственное предприятие "Биофарм" Раствор для консервации живых органов
US5306711A (en) * 1992-06-24 1994-04-26 Georgetown University Organ preservative solution
US5565317A (en) * 1992-06-26 1996-10-15 Torii Pharmaceutical Co., Ltd. Perfusion and storage solution containing sodium lactobionate, sodium dihydrogenphosphate, raffinose, glutathione, allopurinol and nafamostat mesylate
FR2695827B1 (fr) * 1992-09-18 1995-07-28 Pasteur Merieux Serums Vacc Solution de perfusion, de conservation et de reperfusion d'organes.
US6680305B1 (en) * 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
US5702880A (en) * 1993-06-04 1997-12-30 Biotime, Inc. Blood substitute comprising 0-5 mM K+
DE4407863C2 (de) * 1993-06-07 1997-08-07 Mayer Berndt Priv Doz Dr Med Verfahren und Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen
US5436232A (en) * 1994-01-07 1995-07-25 Laevosan-Gesellschaft Mbh Pharmaceutical composition for peritoneal dialysis
US5554497A (en) * 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
US5679565A (en) * 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
DE19527734A1 (de) * 1995-07-28 1997-01-30 Hubert Verhaag Verfahren und Vorrichtung zur Konservierung von Geweben und Organen, insbesondere von Transplantationsgeweben und -organen
US6180404B1 (en) 1996-04-09 2001-01-30 The Board Of Trustees Of Southern Illinois University Cultural medium for maintaining neural cells in ambient atmosphere
US5696152A (en) * 1996-05-07 1997-12-09 Wisconsin Alumni Research Foundation Taxol composition for use as organ preservation and cardioplegic agents
US5843024A (en) * 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US5962213A (en) * 1996-06-14 1999-10-05 Biostore New Zealand Limited Compositions and methods for the preservation of living tissues
US6037116A (en) * 1996-06-14 2000-03-14 Biostore New Zealand, Ltd. Compositions comprising betaine, sodium citrate and sodium chloride and methods for the preservation of biological materials
US5879875A (en) * 1996-06-14 1999-03-09 Biostore New Zealand Compositions and methods for the preservation of living tissues
US6743575B2 (en) 1996-06-14 2004-06-01 Biostore New Zealand Ltd. Compositions and methods for the preservation of living tissues
US6361933B1 (en) 1996-06-14 2002-03-26 Biostore New Zealand Limited Solutions for the preservation of tissues
US6114107A (en) * 1996-06-14 2000-09-05 Biostore New Zealand Limited Composition comprising raffinose, TMAO, sodium citrate and methods for the preservation of living tissues
US20040229203A1 (en) * 1996-06-14 2004-11-18 Biostore New Zealand Ltd. Compositions and methods for the preservation of living tissues
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
US6162642A (en) * 1997-01-23 2000-12-19 Fresenius Ag Agent for dehydrating corneas in organ culture
DE19702210C2 (de) * 1997-01-23 1999-01-14 Fresenius Ag Verwendung von HES zur Entquellung von Hornhäuten in der Organkultur
DE19706111C2 (de) * 1997-02-17 1999-02-18 Fresenius Medical Care De Gmbh Lösung zur Aufbewahrung von Organen
US5968527A (en) * 1997-02-27 1999-10-19 Catholic University Of America, The Protection of living systems from the adverse effects of stress
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
US6977140B1 (en) 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
DE29900874U1 (de) * 1999-01-20 1999-07-22 Knoll AG, 67061 Ludwigshafen Organprotektive Lösungen
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
US6365338B1 (en) 1999-04-27 2002-04-02 David A. Bull Organ preservative solution containing trehalose, anti-oxidant, cations and an energy source
US6544726B1 (en) 1999-05-05 2003-04-08 Knox Van Dyke KVD solution for transplantable organs
US20060275378A9 (en) * 1999-10-26 2006-12-07 Holloway William D Jr Culture media and methods of making and using culture media
US20040126468A1 (en) * 1999-10-26 2004-07-01 Aquaphotonics Food or edible material and beverages: processes, compositions, and products
US20060198901A9 (en) * 1999-10-26 2006-09-07 Holloway William D Jr Drugs, bio-affecting and body treating compositions
US20040121022A1 (en) * 1999-10-26 2004-06-24 Holloway William D. Culture media and methods of making and using culture media
RU2168947C1 (ru) * 2000-04-10 2001-06-20 Бабич Игорь Иванович Способ хирургического лечения идиопатической тромбоцитопенической пурпуры у детей
EP1331941A1 (en) 2000-10-13 2003-08-06 Pike Laboratories, Inc. Organ and biological tissue preservation cold storage solution
US20020115593A1 (en) * 2000-10-13 2002-08-22 Pike Laboratories, Inc. Organ and biological tissue preservation machine perfusion solution
GB0028414D0 (en) * 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz
ITMI20010395A1 (it) * 2001-02-27 2002-08-27 Dompe Spa Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate
JP4570877B2 (ja) * 2002-03-28 2010-10-27 明治製菓株式会社 臓器保存用組成物および臓器の保存方法
EP1367119B1 (en) * 2002-05-28 2008-09-17 Toyo Boseki Kabushiki Kaisha Methods of culturing, storing, and inducing differentiation in cells, instrument for use in the methods and method of using the instrument.
JP2005537006A (ja) 2002-08-28 2005-12-08 ダイアックス、コープ 臓器及び組織の保存方法
US20060121439A1 (en) * 2002-09-18 2006-06-08 Jan Baker Organ preservation and transportation apparatus and method
JP5204947B2 (ja) 2002-11-27 2013-06-05 ディーエムアイ バイオサイエンシズ インコーポレイテッド リン酸受容体化合物の使用、ならびにリン酸受容体化合物を含んでいる、薬学的組成物、スキンケア用の組成物、およびキット
US7998725B2 (en) * 2003-04-04 2011-08-16 Organ Recovery Systems Method and apparatus for holding a plurality of tubes connectible to an organ or tissue container
WO2004089085A2 (en) 2003-04-04 2004-10-21 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
US20040202993A1 (en) * 2003-04-10 2004-10-14 Poo Ramon E. Apparatus and method for organ preservation and transportation
CA2522106A1 (en) * 2003-04-16 2004-10-28 Creative Co., Ltd. Cellular preparation
JP2006524260A (ja) * 2003-04-23 2006-10-26 ヒューマン バイオシステムズ ドナー臓器の貯蔵用の改良された方法及び溶液
EP1475434A1 (en) * 2003-05-09 2004-11-10 Oncoscience AG Method for storing tumor cells
US20050192348A1 (en) * 2003-09-25 2005-09-01 David Bar-Or Methods and products which utilize N-acyl-L-aspartic acid
AU2005218539A1 (en) * 2004-03-01 2005-09-15 Lumen Therapeutics, Llc Compositions and methods for treating diseases
US8900804B2 (en) * 2004-11-22 2014-12-02 Cedars-Sinai Medical Center Methods and solutions for tissue preservation
WO2006057674A2 (en) * 2004-11-24 2006-06-01 The Trustees Of Columbia University In The City Of New York COMPOSITIONS AND METHODS FOR EX VIVO PRESERVATION OF BLOOD VESSELS FOR VASCULAR GRAFTS USING ANALOGUES OF cAMP AND cGMP
US7713686B2 (en) * 2004-12-03 2010-05-11 Biorep Technologies, Inc. Organ preservation container and method
US20060182722A1 (en) * 2005-02-11 2006-08-17 Hering Bernhard J Methods and materials for isolating isogenic islet cells
US20080161423A1 (en) * 2005-03-04 2008-07-03 Atsushi Kudo Organ Function Maintaining or Amelorating Solution
US20070141548A1 (en) * 2005-03-11 2007-06-21 Jorg Kohl Organ transplant solutions and method for transplanting organs
WO2007030198A2 (en) * 2005-07-11 2007-03-15 Human Biosystems Improved methods and solutions for storing donor organs
EP1937059A2 (en) * 2005-07-27 2008-07-02 University Of North Carolina At Charlotte Composition and method for the restoration and preservation of transplant organs procured from dcd donors
US20070048725A1 (en) * 2005-08-25 2007-03-01 Arrington Ben O'mar Machine perfusion of tissue grafts for transplantation
GB0612877D0 (en) * 2006-06-29 2006-08-09 Univ Edinburgh Organ preservation solution
WO2008070557A2 (en) * 2006-12-01 2008-06-12 Women & Infants Hospital Organometallic complexes as therapeutic agents
US20080145919A1 (en) * 2006-12-18 2008-06-19 Franklin Thomas D Portable organ and tissue preservation apparatus, kit and methods
US9511075B2 (en) 2007-01-12 2016-12-06 The University Of Maryland, Baltimore Targeting NCCA-ATP channel for organ protection following ischemic episode
AU2008216612B2 (en) * 2007-02-17 2014-12-04 President And Fellows Of Harvard College Compositions and method for tissue preservation
DE102007026392A1 (de) * 2007-06-06 2008-12-11 Bayer Healthcare Ag Lösungen für die Perfusion und Konservierung von Organen und Geweben
FR2923391B1 (fr) * 2007-11-08 2012-07-27 Biocydex Compositions pour conserver des cellules, des tissus ou des organes, procede d'obtention et utilisations.
WO2009105164A2 (en) 2008-02-15 2009-08-27 President And Fellows Of Harvard College Blood substitute solution
US8288084B2 (en) * 2009-07-12 2012-10-16 Revive Organtech, Inc. Composition and method for flushing and cold/cryo preserving organs, tissues, and cells
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
AU2011257148A1 (en) 2010-05-24 2013-01-10 Digna Biotech, S.L. Composition for the cold storage of organs
RU2436515C1 (ru) * 2010-07-06 2011-12-20 Государственное учреждение Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе Способ оценки качества почечных трансплантатов от доноров с расширенными критериями
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
EP2809152B1 (en) 2012-02-01 2019-11-20 Nayacure Therapeutics Ltd Method for inducing immune tolerance to organ transplants
WO2014017267A1 (ja) 2012-07-25 2014-01-30 国立大学法人大阪大学 組織保存液および組織保存方法
US10433538B2 (en) * 2012-10-12 2019-10-08 University of Pittsburgh—of the Commonwealth System of Higher Education Compositions and methods for organ preservation
EP2978307B1 (en) 2013-03-28 2018-12-26 The Trustees of Columbia University in the City of New York Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation
MY181282A (en) 2013-11-22 2020-12-21 Somahlution Llc Solutions for increasing the stability and shelf life of an organ and tissue preservation solution
US10874098B2 (en) 2015-04-03 2020-12-29 Tx Innovations B.V. Organ preservation composition
CA3047360C (en) * 2017-01-17 2023-09-26 Xvivo Perfusion Ab Organ preservation and/or perfusion solutions
CA3118682A1 (en) 2018-11-04 2020-05-07 Figene, Llc Methods and compositions for treatment of type 1 diabetes using fibroblasts as facilitators of islet engraftment
CA3142424A1 (en) 2019-05-31 2021-01-07 Case Western Reserve University Bax inhibitors and uses thereof
WO2021041836A1 (en) * 2019-08-28 2021-03-04 The Regents Of The University Of Michigan Preservation of organs for transplant and non-transplant surgeries
EP4110050A1 (en) 2020-02-26 2023-01-04 Finless Food Inc. Systems and methods for live fish tissue preservation
WO2023023309A1 (en) 2021-08-20 2023-02-23 Finless Foods Inc. Systems and methods for fish tissue preservation
AU2023309803A1 (en) 2022-07-22 2025-01-09 Grifols Worldwide Operations Limited Stable plasmin compositions for organ preservation and reconditioning
WO2025199047A1 (en) * 2024-03-18 2025-09-25 Wisconsin Alumni Research Foundation Cold storage solution for organs and tissues including whole eyes and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523938A (en) * 1967-12-13 1970-08-11 American Hospital Supply Corp Starch plasma expanders and process of preparation
DE2908436A1 (de) * 1979-03-05 1980-09-25 Fresenius Chem Pharm Ind Kolloidales gefrierschutzmittel
DE3030863A1 (de) * 1980-08-14 1982-03-11 Albrecht M. Prof. Dr.med. 6072 Dreieich Ehrly Verwendung von hydroxyaethylstaerke zur behandlung von durchblutungssstoerungen
DE3272969D1 (en) * 1981-03-16 1986-10-09 Leonora I Jost Anaerobic method for preserving whole blood, tissue and components containing living mammalian cells
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
US4798824A (en) * 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs

Also Published As

Publication number Publication date
NL8803186A (nl) 1989-07-17
BE1003362A3 (fr) 1992-03-10
AU609236B2 (en) 1991-04-26
SE8804661L (sv) 1989-06-30
AU2761688A (en) 1989-06-29
FR2625073A1 (fr) 1989-06-30
CH678912A5 (it) 1991-11-29
DE3843958A1 (de) 1989-07-13
NL193971B (nl) 2000-12-01
GB2213362B (en) 1992-04-22
SE503182C2 (sv) 1996-04-15
JPH0768082B2 (ja) 1995-07-26
KR950015064B1 (ko) 1995-12-21
DE3843958C2 (de) 1994-03-10
NL193971C (nl) 2001-04-03
NZ227516A (en) 1991-02-26
IT8823136A0 (it) 1988-12-28
US4879283A (en) 1989-11-07
GB8830096D0 (en) 1989-02-22
GB2213362A (en) 1989-08-16
HU200885B (en) 1990-09-28
FR2625073B1 (fr) 1993-03-26
KR890009409A (ko) 1989-08-01
HUT49782A (en) 1989-11-28
RU2019965C1 (ru) 1994-09-30
PH27182A (en) 1993-04-16
JPH01246201A (ja) 1989-10-02
ZA889683B (en) 1989-09-27
SE8804661D0 (sv) 1988-12-27

Similar Documents

Publication Publication Date Title
IT1227916B (it) Mezzo di perfusione per la preservazione di organi
DK682388D0 (da) Transportkoeleanlaeg
DK318688D0 (da) Reagensglasholder
FI883575A7 (fi) Lähetinvastaanotinjärjestelmä
IT8324272A1 (it) Sistema per la composizione flessibile di fasci laser
IT8720371A0 (it) Film poliolefinici metallizzabili. procedimento per la preparazione di
IT8821009A0 (it) Procedimento per la preparazione di vetri organici.
NO178515C (no) Lasersystem
IT1221550B (it) Apparecchiatura perfezionata per la lappatura di interni
IT8820495A0 (it) Procedimento per la preparazione di cumene.
FI871605A0 (fi) Anordning foer skaerning av koett.
IT1215592B (it) Procedimento per la selezione di tubetti.
IT8722911A0 (it) Procedimento per la preparazione di monosialoganglioside.
IT8719363A0 (it) Procedimento per la produzione di calcourea.
IT8522630A0 (it) Procedimento per la conservazione di composti organici.
IT8723035A0 (it) Procedimento per la preparazione di n acilaniline.
FI894035A0 (fi) Foerfarande foer framstaellning av nya substituerade pyridazinoner.
IT8722754A0 (it) Procedimento per la microincapsulazione di sostanze solide bassogondenti.
IT1231506B (it) Procedimento per la purificazione di polieteri polioli.
DE69002859D1 (de) Verfahren zur Haltbarmachung von Natriumperboratmonohydrat.
IT1227884B (it) Attivatore per osteoblasto
IT8719073A0 (it) Procedimento per la preparazione di omega-isopropossifenolo.
IT8820949A0 (it) Procedimento per la preparazione di derivati della (trans) 4 fenil lprolina.
IT1157951B (it) Procedimento per la preparazione di antibiotici betalattamici
FI881091A7 (fi) Menetelmä isobutyylibentseenin valmistamiseksi isobutenyylisyklohekseenistä.

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961227