IT1232827B - Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle - Google Patents

Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle

Info

Publication number
IT1232827B
IT1232827B IT8947794A IT4779489A IT1232827B IT 1232827 B IT1232827 B IT 1232827B IT 8947794 A IT8947794 A IT 8947794A IT 4779489 A IT4779489 A IT 4779489A IT 1232827 B IT1232827 B IT 1232827B
Authority
IT
Italy
Prior art keywords
prepare
apply
biologically active
formulations containing
active proteins
Prior art date
Application number
IT8947794A
Other languages
English (en)
Other versions
IT8947794A0 (it
Inventor
Jean-Michel Dayer
Philippe Lucien Seckinger
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT8947794A0 publication Critical patent/IT8947794A0/it
Application granted granted Critical
Publication of IT1232827B publication Critical patent/IT1232827B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT8947794A 1988-03-31 1989-03-30 Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle IT1232827B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888807803A GB8807803D0 (en) 1988-03-31 1988-03-31 Biochemical product

Publications (2)

Publication Number Publication Date
IT8947794A0 IT8947794A0 (it) 1989-03-30
IT1232827B true IT1232827B (it) 1992-03-05

Family

ID=10634493

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8947794A IT1232827B (it) 1988-03-31 1989-03-30 Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle

Country Status (12)

Country Link
JP (1) JPH02117700A (it)
KR (1) KR890014125A (it)
AU (1) AU3228789A (it)
BE (1) BE1001845A4 (it)
DE (1) DE3910323A1 (it)
DK (1) DK156589A (it)
FR (1) FR2629345A1 (it)
GB (2) GB8807803D0 (it)
IL (1) IL89804A0 (it)
IT (1) IT1232827B (it)
NL (1) NL8900779A (it)
SE (1) SE8901115L (it)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83878A (en) * 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
US5811261A (en) * 1988-09-12 1998-09-22 Yeda Research And Development Co. Ltd. Expression of the recombinant tumor necrosis factor binding protein I (TBP-I)
DK0393438T3 (da) * 1989-04-21 2005-05-30 Amgen Inc TNF-receptor, TNF-bindende proteiner og DNAér, der koder herfor
US6221675B1 (en) 1989-04-21 2001-04-24 Amgen, Inc. TNF receptors, TNF binding proteins and DNAs coding for them
US7264944B1 (en) 1989-04-21 2007-09-04 Amgen Inc. TNF receptors, TNF binding proteins and DNAs coding for them
IL95031A (en) * 1989-07-18 2007-03-08 Amgen Inc Method for the production of a human recombinant tumor necrosis factor inhibitor
US6143866A (en) * 1989-07-18 2000-11-07 Amgen, Inc. Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
WO1991003553A1 (en) * 1989-09-05 1991-03-21 Immunex Corporation TUMOR NECROSIS FACTOR-α AND -β RECEPTORS
US5945397A (en) * 1989-09-05 1999-08-31 Immunex Corporation Purified p75 (type II) tumor necrosis factor receptor polypeptides
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
US5605690A (en) * 1989-09-05 1997-02-25 Immunex Corporation Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
EP0939121B2 (de) * 1989-09-12 2007-12-26 AHP Manufacturing B.V. TFN-bindende Proteine
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
WO1992001002A1 (en) * 1990-07-11 1992-01-23 Teijin Limited Tumor necrosis factor activity inhibitor and production thereof
US5304634A (en) * 1990-10-12 1994-04-19 Hoechst Aktiengesellschaft Inhibitors for the formation of tumor necrosis factor
ES2145744T5 (es) * 1991-01-18 2008-02-01 Amgen Inc. Procedimientos para tratar las enfermedades inducidas por el factor de necrosis tumoral.
WO1993004375A1 (en) * 1991-08-23 1993-03-04 Nchip, Inc. Burn-in technologies for unpackaged integrated circuits
IT1276040B1 (it) * 1993-07-27 1997-10-24 Angelini Francesco Ist Ricerca Uso della benzidamina nel trattamento di stati patologici causati dal tnf
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
ES2312179T3 (es) 1996-12-06 2009-02-16 Amgen Inc. Terapia combinada que utiliza un inhibidor del il-1 para el tratamiento de enfermedades mediadas por el il-1.
WO1998024463A2 (en) 1996-12-06 1998-06-11 Amgen Inc. Combination therapy using a tnf binding protein for treating tnf-mediated diseases
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
EP2295081B1 (en) 2001-06-26 2018-10-31 Amgen Inc. Antibodies to OPGL
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
WO2004060911A2 (en) 2002-12-30 2004-07-22 Amgen Inc. Combination therapy with co-stimulatory factors
US7767206B2 (en) 2006-10-02 2010-08-03 Amgen Inc. Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
TW201117824A (en) 2009-10-12 2011-06-01 Amgen Inc Use of IL-17 receptor a antigen binding proteins
PH12012501364A1 (en) 2010-01-15 2012-10-22 Amgen K A Inc Antibody formulation and therapeutic regimens
WO2013016220A1 (en) 2011-07-22 2013-01-31 Amgen Inc. Il-17 receptor a is required for il-17c biology
CA2944605C (en) 2014-03-31 2023-10-17 Kirin-Amgen, Inc. Methods of treating nail and scalp psoriasis

Also Published As

Publication number Publication date
IT8947794A0 (it) 1989-03-30
FR2629345A1 (fr) 1989-10-06
DK156589A (da) 1989-10-01
SE8901115D0 (sv) 1989-03-30
DE3910323A1 (de) 1989-10-19
NL8900779A (nl) 1989-10-16
AU3228789A (en) 1989-10-05
IL89804A0 (en) 1989-09-28
GB2218101A (en) 1989-11-08
KR890014125A (ko) 1989-10-21
SE8901115L (sv) 1989-10-01
JPH02117700A (ja) 1990-05-02
BE1001845A4 (fr) 1990-03-20
GB8807803D0 (en) 1988-05-05
DK156589D0 (da) 1989-03-30
GB8907148D0 (en) 1989-05-10

Similar Documents

Publication Publication Date Title
IT1232827B (it) Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle
FI893542L (fi) Entsyymielektrodit ja menetelmä niiden valmistamiseksi
FI862095A7 (fi) Käyttösysteemi aktiivisia aineosia varten ja menetelmä sen valmistamiseksi.
FR2630546B1 (fr) Electrode enzymatique et son procede de preparation
NO865076D0 (no) Flere ganger oppdelte transdermale og dermale plastere.
IT8520242A0 (it) Polipeptide umano fisiologicamente attivo.
FI883936A7 (fi) Sokeritaudin hoito, hoidossa käyttökelpoiset valmisteet ja niiden valmistus
FI891591A7 (fi) Ihonhoitokoostumus ja menetelmä sen valmistamiseksi
FI864654L (fi) Menetelmä modifioidun ihmisen t-PA-proteiinin valmistamiseksi
DK273689A (da) 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
IT1196484B (it) Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
JPS539762A (en) Hydoxyysuccinimideeester derivative* its preparation and method of bonding biologically active proteins
FI873905A7 (fi) Terapeuttinen koostumus ja menetelmä.
FI864164A7 (fi) Ihmis- -interferonin biologisesti aktiivisia johdoksia, niiden valmistus ja tällaisia johdoksia sisältävlääkkeitä.
DK291886A (da) 1,8-broforbundne 4-quinolon-3-carboxylsyrer, deres fremstilling og anvendelse i laegemidler og dyrefoder
DK109590A (da) Biologisk aktivt protein
IS3514A7 (is) Aðferð til að vinna líffræðilega virk efni
NO860344L (no) Vevskultur og fremstilling i permeable geler.
FI833451A7 (fi) Kudosviljelmä ja solun kasvua edistävä aines sekä sen valmistusmenetelmä.
FR2627778B1 (fr) Gene de structure, proteine endotoxine correspondante et application insecticide
FR2579599B1 (fr) Substance physiologiquement active tpi et procede de preparation
FR2584401B1 (fr) Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
FR2540107B1 (fr) Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI895899A7 (fi) Uudet trombolyyttiset proteiinit, menetelmä niiden valmistamiseksi ja näitä aktiiviaineina sisältävät lääkkeet
FR2626880B1 (fr) Derives n-substitues de 2-amino-1-phenylpropanone, procede de preparation et utilisation en therapeutique