IT1241761B - Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione - Google Patents

Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione

Info

Publication number: IT1241761B
Authority: IT; Italy
Prior art keywords: neurokinin; antagonists; salts; synthetic peptides; manufacturing procedures
Prior art date: 1990-08-03

Application number

IT9455A

Other languages

English (en)

Other versions

IT9009455A0 (it

IT9009455A1 (it

Inventor

Paolo Rovero

Vittorio Pestellini

Laura Quartara

Carlo Alberto Maggi

Riccardo Patacchini

Sandro Giuliani

Original Assignee

Menarini Farma Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-03

Filing date

1990-08-03

Publication date

1994-02-01

1990-08-03 Application filed by Menarini Farma Ind filed Critical Menarini Farma Ind

1990-08-03 Priority to IT9455A priority Critical patent/IT1241761B/it

1990-08-03 Publication of IT9009455A0 publication Critical patent/IT9009455A0/it

1991-07-26 Priority to DE69104987T priority patent/DE69104987T2/de

1991-07-26 Priority to PCT/IT1991/000067 priority patent/WO1992002546A1/en

1991-07-26 Priority to ES91914235T priority patent/ES2063519T3/es

1991-07-26 Priority to EP91914235A priority patent/EP0541662B1/en

1991-07-26 Priority to AU83191/91A priority patent/AU8319191A/en

1991-08-02 Priority to PT98558A priority patent/PT98558A/pt

1992-02-04 Publication of IT9009455A1 publication Critical patent/IT9009455A1/it

1994-02-01 Application granted granted Critical

1994-02-01 Publication of IT1241761B publication Critical patent/IT1241761B/it

Links

HEAUFJZALFKPBA-JPQUDPSNSA-N (3s)-3-[[(2s,3r)-2-[[(2s)-6-amino-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[2-[[(2s)-1-[[(2s)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amin Chemical compound C([C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)C(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 HEAUFJZALFKPBA-JPQUDPSNSA-N 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

IT9455A 1990-08-03 1990-08-03 Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione IT1241761B (it)

Priority Applications (7)

Application Number	Priority Date	Filing Date	Title
IT9455A IT1241761B (it)	1990-08-03	1990-08-03	Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione
DE69104987T DE69104987T2 (de)	1990-08-03	1991-07-26	Synthetische peptide mit neurokinin a antagonistischer wirkung, deren salze und verfahren zu deren herstellung.
PCT/IT1991/000067 WO1992002546A1 (en)	1990-08-03	1991-07-26	Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes
ES91914235T ES2063519T3 (es)	1990-08-03	1991-07-26	Peptidos sinteticos que antagonizan neuroquinina a, sus sales y sus procedimientos de preparacion.
EP91914235A EP0541662B1 (en)	1990-08-03	1991-07-26	Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes
AU83191/91A AU8319191A (en)	1990-08-03	1991-07-26	Synthetic peptides that antagonize neurokinin a, their salts and their manufacturing processes
PT98558A PT98558A (pt)	1990-08-03	1991-08-02	Processo para a preparacao de peptidos sinteticos que antagonizam neuroquinina ae de composicoes farmaceuticas que os contem

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT9455A IT1241761B (it)	1990-08-03	1990-08-03	Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione

Publications (3)

Publication Number	Publication Date
IT9009455A0 IT9009455A0 (it)	1990-08-03
IT9009455A1 IT9009455A1 (it)	1992-02-04
IT1241761B true IT1241761B (it)	1994-02-01

Family

ID=11130398

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT9455A IT1241761B (it)	1990-08-03	1990-08-03	Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione

Country Status (7)

Country	Link
EP (1)	EP0541662B1 (it)
AU (1)	AU8319191A (it)
DE (1)	DE69104987T2 (it)
ES (1)	ES2063519T3 (it)
IT (1)	IT1241761B (it)
PT (1)	PT98558A (it)
WO (1)	WO1992002546A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0528312B1 (en) *	1991-08-13	1997-07-16	Takeda Chemical Industries, Ltd.	Cyclic peptides and use thereof
US5367053A (en) *	1993-05-19	1994-11-22	Houghten Pharmaceuticals, Inc.	Opioid peptide inhibitors
US5521156A (en) *	1994-02-03	1996-05-28	Merrell Pharmaceuticals Inc.	Cyclic neurokinin A antagonists
BR112021023477A2 (pt) *	2019-05-21	2022-02-15	Eyebio Korea	Novo composto peptídico, composição farmacêutica para prevenir ou tratar inflamação, composição de alimento para prevenir ou amenizar a inflamação e composição de cosmético tendo um efeito anti inflamatório

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1233696B (it) *	1989-05-29	1992-04-14	Menarini Farma Ind	Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione

1990
- 1990-08-03 IT IT9455A patent/IT1241761B/it active IP Right Grant
1991
- 1991-07-26 ES ES91914235T patent/ES2063519T3/es not_active Expired - Lifetime
- 1991-07-26 WO PCT/IT1991/000067 patent/WO1992002546A1/en not_active Ceased
- 1991-07-26 EP EP91914235A patent/EP0541662B1/en not_active Expired - Lifetime
- 1991-07-26 DE DE69104987T patent/DE69104987T2/de not_active Expired - Fee Related
- 1991-07-26 AU AU83191/91A patent/AU8319191A/en not_active Abandoned
- 1991-08-02 PT PT98558A patent/PT98558A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
IT9009455A0 (it)	1990-08-03
DE69104987D1 (de)	1994-12-08
DE69104987T2 (de)	1995-04-20
IT9009455A1 (it)	1992-02-04
EP0541662B1 (en)	1994-11-02
ES2063519T3 (es)	1995-01-01
EP0541662A1 (en)	1993-05-19
PT98558A (pt)	1992-06-30
WO1992002546A1 (en)	1992-02-20
AU8319191A (en)	1992-03-02

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Legal Events

Date	Code	Title	Description
1994-02-01	0001	Granted
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19950829