IT1247879B - 6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali. - Google Patents

6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali.

Info

Publication number
IT1247879B
IT1247879B ITMI910600A ITMI910600A IT1247879B IT 1247879 B IT1247879 B IT 1247879B IT MI910600 A ITMI910600 A IT MI910600A IT MI910600 A ITMI910600 A IT MI910600A IT 1247879 B IT1247879 B IT 1247879B
Authority
IT
Italy
Prior art keywords
dioni
benzo
bis
ftalazin
substituted amino
Prior art date
Application number
ITMI910600A
Other languages
English (en)
Inventor
Ambrogio Oliva
Silvano Spinelli
Ernesto Menta
Sergio Tognella
Original Assignee
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia filed Critical Boehringer Mannheim Italia
Priority to ITMI910600A priority Critical patent/IT1247879B/it
Publication of ITMI910600A0 publication Critical patent/ITMI910600A0/it
Priority to JP4504669A priority patent/JPH06505013A/ja
Priority to DE69202762T priority patent/DE69202762T2/de
Priority to ES92905252T priority patent/ES2073915T3/es
Priority to EP92905252A priority patent/EP0574433B1/en
Priority to PCT/EP1992/000454 priority patent/WO1992015307A1/en
Priority to AU13285/92A priority patent/AU1328592A/en
Publication of ITMI910600A1 publication Critical patent/ITMI910600A1/it
Application granted granted Critical
Publication of IT1247879B publication Critical patent/IT1247879B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invenzione si riferisce a nuovi 6,9-bis(amino sostituiti)benzo[g]ftalazin-5,10-dioni, a un metodo per la loro preparazione ed alle composizioni farmaceutiche che li contengono.
ITMI910600A 1991-03-08 1991-03-08 6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali. IT1247879B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI910600A IT1247879B (it) 1991-03-08 1991-03-08 6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali.
JP4504669A JPH06505013A (ja) 1991-03-08 1992-03-02 抗癌剤としての６，９−ビス（アミノ置換）ベンゾ〔ｇ〕フタラジン−５，１０−ジオン
DE69202762T DE69202762T2 (de) 1991-03-08 1992-03-02 6,9-Bis(amino substituierte) Benzo(G)Phthalazin-5,10-Dionen als Antikrebs-mittel.
ES92905252T ES2073915T3 (es) 1991-03-08 1992-03-02 6,9-bis(amino sustituido)benzo g)ftalazin-5,10-diona como agentes antitumorales.
EP92905252A EP0574433B1 (en) 1991-03-08 1992-03-02 6,9-BIS(AMINO SUBSTITUTED)BENZO g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS
PCT/EP1992/000454 WO1992015307A1 (en) 1991-03-08 1992-03-02 6,9-BIS(AMINO SUBSTITUTED)BENZO[g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS
AU13285/92A AU1328592A (en) 1991-03-08 1992-03-02 6,9-bis(amino substituted)benzo{g}phthalazine-5,10-diones as antitumor agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910600A IT1247879B (it) 1991-03-08 1991-03-08 6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali.

Publications (3)

Publication Number Publication Date
ITMI910600A0 ITMI910600A0 (it) 1991-03-08
ITMI910600A1 ITMI910600A1 (it) 1992-09-08
IT1247879B true IT1247879B (it) 1995-01-05

Family

ID=11358923

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910600A IT1247879B (it) 1991-03-08 1991-03-08 6,9-bis (amino sostituiti) benzo(g) ftalazin-5,10-dioni come farmaci antitumorali.

Country Status (7)

Country Link
EP (1) EP0574433B1 (it)
JP (1) JPH06505013A (it)
AU (1) AU1328592A (it)
DE (1) DE69202762T2 (it)
ES (1) ES2073915T3 (it)
IT (1) IT1247879B (it)
WO (1) WO1992015307A1 (it)

Also Published As

Publication number Publication date
EP0574433B1 (en) 1995-05-31
DE69202762D1 (de) 1995-07-06
AU1328592A (en) 1992-10-06
DE69202762T2 (de) 1995-12-07
EP0574433A1 (en) 1993-12-22
ITMI910600A1 (it) 1992-09-08
JPH06505013A (ja) 1994-06-09
ITMI910600A0 (it) 1991-03-08
ES2073915T3 (es) 1995-08-16
WO1992015307A1 (en) 1992-09-17

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970329