IT1248059B - Insufflatore multidose per farmaci in polvere - Google Patents

Insufflatore multidose per farmaci in polvere

Info

Publication number
IT1248059B
IT1248059B ITMI911643A ITMI911643A IT1248059B IT 1248059 B IT1248059 B IT 1248059B IT MI911643 A ITMI911643 A IT MI911643A IT MI911643 A ITMI911643 A IT MI911643A IT 1248059 B IT1248059 B IT 1248059B
Authority
IT
Italy
Prior art keywords
cup
drug
unit
tank
insufflation
Prior art date
Application number
ITMI911643A
Other languages
English (en)
Inventor
Salvatore Cocozza
Original Assignee
Miat Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat Spa filed Critical Miat Spa
Publication of ITMI911643A0 publication Critical patent/ITMI911643A0/it
Priority to ITMI911643A priority Critical patent/IT1248059B/it
Priority to US07/881,433 priority patent/US5250287A/en
Priority to ES92108490T priority patent/ES2076608T3/es
Priority to EP92108490A priority patent/EP0518087B1/en
Priority to AT92108490T priority patent/ATE125161T1/de
Priority to DE69203541T priority patent/DE69203541T2/de
Priority to DK92108490.1T priority patent/DK0518087T3/da
Priority to CA002070297A priority patent/CA2070297C/en
Priority to JP4179291A priority patent/JPH05200115A/ja
Publication of ITMI911643A1 publication Critical patent/ITMI911643A1/it
Application granted granted Critical
Publication of IT1248059B publication Critical patent/IT1248059B/it
Priority to GR950402711T priority patent/GR3017598T3/el

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • B05B11/065—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time
    • B05B11/067—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time the particulate material being separated from the main storage by a dosing device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/20—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates
    • G01F11/24—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075—Bulb type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un insufflatore multidose, per somministrare per via nasale farmaci sotto forma di polvere fine o micronizzata, comprende un'unità di serbatoio di prelievo e dosaggio (60,64) del farmaco contenuto nell'unità di serbatoio (34), ed un'unità di insufflazione (42,46) comprendente una pompetta (42), azionabile manualmente per generare una corrente d'aria in un canale (26) per trasportare la singola dose di farmaco nella cavità nasale del paziente. L'unità di prelievo e dosaggio comprende un dispositivo convogliatore (60) dotato di almeno una tazza (64) per prelevare una dose di farmaco del serbatoio (34) e trasportarlo in una posizione di insufflazione. La tazza (64) ha un foro di fondo (66) coassiale attraverso il quale, quando la tazza è nella posizione di insufflazione, passa la corrente d'aria generata dalla pompetta. Il foro (66) ha una luce sostanzialmente più piccola dell'imboccatura della tazza (64) e tale da impedire, per effetto "arco", la caduta del farmaco in polvere attraverso di esso.
ITMI911643A 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere IT1248059B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere
US07/881,433 US5250287A (en) 1991-06-14 1992-05-11 Multi-dose insufflator for medicaments in powder form
AT92108490T ATE125161T1 (de) 1991-06-14 1992-05-20 Einblasgerät für mehrfachdosierungen von pulverförmigen medikamenten.
EP92108490A EP0518087B1 (en) 1991-06-14 1992-05-20 Multi-dose insufflator for medicaments in powder form
ES92108490T ES2076608T3 (es) 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo.
DE69203541T DE69203541T2 (de) 1991-06-14 1992-05-20 Einblasgerät für Mehrfachdosierungen von pulverförmigen Medikamenten.
DK92108490.1T DK0518087T3 (da) 1991-06-14 1992-05-20 Multidosisinsufflationsapparat til pulverformede medikamenter
CA002070297A CA2070297C (en) 1991-06-14 1992-06-03 Multi-dose insufflator for medicaments in powder form
JP4179291A JPH05200115A (ja) 1991-06-14 1992-06-12 粉末状薬剤用マルチドース吹き込み器
GR950402711T GR3017598T3 (en) 1991-06-14 1995-10-02 Multi-dose insufflator for medicaments in powder form.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere

Publications (3)

Publication Number Publication Date
ITMI911643A0 ITMI911643A0 (it) 1991-06-14
ITMI911643A1 ITMI911643A1 (it) 1992-12-14
IT1248059B true IT1248059B (it) 1995-01-05

Family

ID=11360122

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere

Country Status (10)

Country Link
US (1) US5250287A (it)
EP (1) EP0518087B1 (it)
JP (1) JPH05200115A (it)
AT (1) ATE125161T1 (it)
CA (1) CA2070297C (it)
DE (1) DE69203541T2 (it)
DK (1) DK0518087T3 (it)
ES (1) ES2076608T3 (it)
GR (1) GR3017598T3 (it)
IT (1) IT1248059B (it)

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CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
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Also Published As

Publication number Publication date
ATE125161T1 (de) 1995-08-15
DE69203541D1 (de) 1995-08-24
EP0518087B1 (en) 1995-07-19
ITMI911643A1 (it) 1992-12-14
CA2070297C (en) 1999-01-26
US5250287A (en) 1993-10-05
ITMI911643A0 (it) 1991-06-14
EP0518087A1 (en) 1992-12-16
JPH05200115A (ja) 1993-08-10
ES2076608T3 (es) 1995-11-01
DK0518087T3 (da) 1995-11-27
GR3017598T3 (en) 1996-01-31
CA2070297A1 (en) 1992-12-15
DE69203541T2 (de) 1996-01-11

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950628