ES2076608T3 - Insuflador multi-dosis para medicamentos en forma de polvo. - Google Patents

Insuflador multi-dosis para medicamentos en forma de polvo.

Info

Publication number
ES2076608T3
ES2076608T3 ES92108490T ES92108490T ES2076608T3 ES 2076608 T3 ES2076608 T3 ES 2076608T3 ES 92108490 T ES92108490 T ES 92108490T ES 92108490 T ES92108490 T ES 92108490T ES 2076608 T3 ES2076608 T3 ES 2076608T3
Authority
ES
Spain
Prior art keywords
receptacle
deposit
powder
dose
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92108490T
Other languages
English (en)
Inventor
Salvatore Cocozza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Miat SpA
Original Assignee
Miat SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat SpA filed Critical Miat SpA
Application granted granted Critical
Publication of ES2076608T3 publication Critical patent/ES2076608T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • B05B11/065—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time
    • B05B11/067—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time the particulate material being separated from the main storage by a dosing device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/20—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates
    • G01F11/24—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075—Bulb type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTA UN INSUFLADOR MULTIDOSIS PARA LA ADMINISTRACION NASAL DE MEDICAMENTOS EN FORMA DE POLVO FINO O MICRONIZADO QUE COMPRENDE UN DEPOSITO (34), UNA UNIDAD (60, 64) PARA EXTRAER Y MEDIR EL MEDICAMENTO CONTENIDO EN EL DEPOSITO, Y UNA UNIDAD INSUFLADORA (42, 46) QUE COMPRENDE UNA BOMBA (42) QUE FUNCIONA MANUALMENTE PARA GENERAR UNA CORRIENTE DE AIRE EN EL INTERIOR DEL CANAL (26) PARA TRANSPORTAR UNA DOSIS INDIVIDUAL DE MEDICAMENTO AL INTERIOR DE LA CAVIDAD NASAL DEL PACIENTE. LA UNIDAD DE EXTRACCION Y MEDIDA COMPRENDE UN DISPOSITIVO TRANSPORTADOR (60) PROVISTO CON AL MENOS UN RECEPTACULO (64) PARA EXTRAER UNA DOSIS DEL MEDICAMENTO DEL DEPOSITO (34) Y TRANSPORTARLO HASTA LA POSICION DE INSUFLADO. EL RECEPTACULO (64) TIENE UN ORIFICIO COAXIAL EN SU BASE (66) A TRAVES DEL CUAL PASA LA CORRIENTE DE AIRE GENERADA POR LA BOMBA CUANDO EL RECEPTACULO SE ENCUENTRA EN LA POSICION DE INSUFLADO. EL ORIFICIO (66) TIENE UN TAMAÑO SUBSTANCIALMENTE MAS PEQUEÑO QUE LA BOCA DEL RECEPTACULO Y ESTO ES ASIPARA EVITAR QUE EL MEDICAMENTO EN POLVO CAIGA A TRAVES DEL ORIFICIO, EN VIRTUD DE UN EFECTO DE ARQUEAMIENTO.
ES92108490T 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo. Expired - Lifetime ES2076608T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere

Publications (1)

Publication Number Publication Date
ES2076608T3 true ES2076608T3 (es) 1995-11-01

Family

ID=11360122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92108490T Expired - Lifetime ES2076608T3 (es) 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo.

Country Status (10)

Country Link
US (1) US5250287A (es)
EP (1) EP0518087B1 (es)
JP (1) JPH05200115A (es)
AT (1) ATE125161T1 (es)
CA (1) CA2070297C (es)
DE (1) DE69203541T2 (es)
DK (1) DK0518087T3 (es)
ES (1) ES2076608T3 (es)
GR (1) GR3017598T3 (es)
IT (1) IT1248059B (es)

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DE69230613T2 (de) * 1991-07-02 2000-12-28 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
DK0674533T3 (da) * 1992-12-18 1999-09-27 Schering Corp Inhalator for medikamenter i pulverform
EP0652022B1 (en) * 1993-05-12 1999-01-27 Teijin Limited Device and method for dispensing powdered medicine in multiple doses
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
DE4415462C1 (de) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhalator
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
DE19518810A1 (de) * 1995-05-26 1996-11-28 Bayer Ag Nasal-Applikator
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
IN188288B (es) * 1996-10-01 2002-08-31 Cipla Ltd
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
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US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
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ID28302A (id) * 1999-01-14 2001-05-10 Teijin Ltd Alat untuk mengumpankan suatu bubuk dalam jumlah tertentu
US6116234A (en) * 1999-02-01 2000-09-12 Iep Pharmaceutical Devices Inc. Metered dose inhaler agitator
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US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
JP3950738B2 (ja) * 2002-05-14 2007-08-01 株式会社 バイオアクティス 鼻腔用粉状薬剤施薬装置
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
CN1684732B (zh) 2002-10-11 2010-04-21 大冢制药株式会社 粉末吸入器
WO2004039415A2 (en) 2002-10-28 2004-05-13 Northgate Technologies Inc. Dual-capacity insufflator tube
US7654975B2 (en) * 2003-04-24 2010-02-02 Northgate Technologies, Inc. Mixed-gas insufflation system
FI20031158L (fi) * 2003-08-15 2005-02-16 Perlos Oyj Inhalaattori
ES2336796T3 (es) * 2003-10-07 2010-04-16 Northgate Technologies Incorporated Sistema para suministrar una sustancia a una cavitacion corporal.
CN100515511C (zh) * 2003-10-09 2009-07-22 株式会社;生命科学活效 鼻腔用粉状药剂施药装置
CA2771129C (en) 2003-10-31 2015-09-29 Trudell Medical International System and method for manipulating a catheter for delivering a substance to a body cavity
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
US20090253654A1 (en) * 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
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JP4948534B2 (ja) * 2006-06-27 2012-06-06 大塚製薬株式会社 粉末吸入器
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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
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US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
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IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
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Also Published As

Publication number Publication date
ATE125161T1 (de) 1995-08-15
DE69203541D1 (de) 1995-08-24
EP0518087B1 (en) 1995-07-19
ITMI911643A1 (it) 1992-12-14
CA2070297C (en) 1999-01-26
US5250287A (en) 1993-10-05
ITMI911643A0 (it) 1991-06-14
EP0518087A1 (en) 1992-12-16
JPH05200115A (ja) 1993-08-10
DK0518087T3 (da) 1995-11-27
IT1248059B (it) 1995-01-05
GR3017598T3 (en) 1996-01-31
CA2070297A1 (en) 1992-12-15
DE69203541T2 (de) 1996-01-11

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