IT1262954B - Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi. - Google Patents

Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi.

Info

Publication number
IT1262954B
IT1262954B ITRM920506A ITRM920506A IT1262954B IT 1262954 B IT1262954 B IT 1262954B IT RM920506 A ITRM920506 A IT RM920506A IT RM920506 A ITRM920506 A IT RM920506A IT 1262954 B IT1262954 B IT 1262954B
Authority
IT
Italy
Prior art keywords
antibodies against
lpg
complexes
antigenic regions
direct antibodies
Prior art date
Application number
ITRM920506A
Other languages
English (en)
Original Assignee
Ist Farmacoterapico It Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Farmacoterapico It Spa filed Critical Ist Farmacoterapico It Spa
Publication of ITRM920506A0 publication Critical patent/ITRM920506A0/it
Priority to ITRM920506A priority Critical patent/IT1262954B/it
Priority to PCT/IT1993/000069 priority patent/WO1994001458A1/en
Priority to ES93916141T priority patent/ES2111757T3/es
Priority to KR1019940704823A priority patent/KR100237250B1/ko
Priority to AT93916141T priority patent/ATE160359T1/de
Priority to EP93916141A priority patent/EP0649433B1/en
Priority to DE69315341T priority patent/DE69315341T2/de
Priority to AU45823/93A priority patent/AU680198B2/en
Priority to US08/351,284 priority patent/US5747643A/en
Priority to RU94046337A priority patent/RU2141969C1/ru
Priority to DK93916141T priority patent/DK0649433T3/da
Priority to CA002139518A priority patent/CA2139518C/en
Priority to JP6503153A priority patent/JP2958118B2/ja
Priority to BR9306663A priority patent/BR9306663A/pt
Publication of ITRM920506A1 publication Critical patent/ITRM920506A1/it
Priority to US08/667,971 priority patent/US5877294A/en
Priority to US08/667,970 priority patent/US5759792A/en
Application granted granted Critical
Publication of IT1262954B publication Critical patent/IT1262954B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Sono descritti peptidi compresi nella proteina di 100 KDa del complesso TLP (proteine liberate da tumori) ad attività antigenica, anticorpi contro di essi capaci di reagire con TLP per la diagnostica e la clinica.
ITRM920506A 1992-07-03 1992-07-03 Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi. IT1262954B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
ITRM920506A IT1262954B (it) 1992-07-03 1992-07-03 Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi.
US08/351,284 US5747643A (en) 1992-07-03 1993-07-01 Antigenic regions of tumor-liberated particles (TLP) complexes and antibodies against the sames
DK93916141T DK0649433T3 (da) 1992-07-03 1993-07-01 Antigeniske regioner fra komplekser af tumorfrigivne partikler (TLP) og antistoffer mod sådanne.
KR1019940704823A KR100237250B1 (ko) 1992-07-03 1993-07-01 Tlp 복합체에 대한 항원성 부위와 이의 항체
AT93916141T ATE160359T1 (de) 1992-07-03 1993-07-01 Antigene regionen von tumorfreigestzten partikeln (tlp) komplexen und antikörper die sie erkennen.
EP93916141A EP0649433B1 (en) 1992-07-03 1993-07-01 Antigenic regions of tumour-liberated particles (tlp) complexes and antibodies against them
DE69315341T DE69315341T2 (de) 1992-07-03 1993-07-01 Antigene regionen von tumorfreigestzten partikeln (tlp) komplexen und antikörper die sie erkennen.
AU45823/93A AU680198B2 (en) 1992-07-03 1993-07-01 Antigenic regions of tumour-liberated particles (TLP) complexes and antibodies against them
PCT/IT1993/000069 WO1994001458A1 (en) 1992-07-03 1993-07-01 Antigenic regions of tumour-liberated particles (tlp) complexes and antibodies against them
RU94046337A RU2141969C1 (ru) 1992-07-03 1993-07-01 Антигенные пептиды, способ обнаружения выделяемых опухолями частиц
ES93916141T ES2111757T3 (es) 1992-07-03 1993-07-01 Regiones antigenicas de complejos de particulas liberadas por tumores (tlp) y anticuerpos contra los mismos.
CA002139518A CA2139518C (en) 1992-07-03 1993-07-01 Antigenic regions of tlp complexes and antibodies against the same
JP6503153A JP2958118B2 (ja) 1992-07-03 1993-07-01 腫瘍放出粒子（ｔｌｐ）複合体の抗原性領域とそれらに対する抗体
BR9306663A BR9306663A (pt) 1992-07-03 1993-07-01 Regiões antigênicas de complexos de partículas liberadas por tumores (TLP) e anticorpos contra os mesmos
US08/667,971 US5877294A (en) 1992-07-03 1996-06-19 Antigenic regions of tumor-liberated particles (TLP) complexes and antibodies against the same
US08/667,970 US5759792A (en) 1992-07-03 1996-06-19 Antigenic regions of tumour-liberated particles (TLP) complexes and antibodies against the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920506A IT1262954B (it) 1992-07-03 1992-07-03 Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi.

Publications (3)

Publication Number Publication Date
ITRM920506A0 ITRM920506A0 (it) 1992-07-03
ITRM920506A1 ITRM920506A1 (it) 1994-01-03
IT1262954B true IT1262954B (it) 1996-07-23

Family

ID=11401092

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920506A IT1262954B (it) 1992-07-03 1992-07-03 Regioni antigeniche dei complessi tpl e anticorpi diretti contro di essi.

Country Status (14)

Country Link
US (3) US5747643A (it)
EP (1) EP0649433B1 (it)
JP (1) JP2958118B2 (it)
KR (1) KR100237250B1 (it)
AT (1) ATE160359T1 (it)
AU (1) AU680198B2 (it)
BR (1) BR9306663A (it)
CA (1) CA2139518C (it)
DE (1) DE69315341T2 (it)
DK (1) DK0649433T3 (it)
ES (1) ES2111757T3 (it)
IT (1) IT1262954B (it)
RU (1) RU2141969C1 (it)
WO (1) WO1994001458A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1284870B1 (it) 1996-07-10 1998-05-22 Ist Farmacoterapico It Spa Peptidi dei complessi tlp da carcinomi dell'apparato urogenitale e anticorpi diretti contro di essi
IT1294967B1 (it) * 1996-10-09 1999-04-23 Ist Farmacoterapico It Spa Composizione immunogenica da tlp
IT1317853B1 (it) * 2000-02-25 2003-07-15 Unihart Corp Peptidi tlp e sequenze di dna che li codificano.
US20030157116A1 (en) * 2000-02-25 2003-08-21 Giulio Tarro Tlp peptides and dna sequences coding the same
JP2004518712A (ja) 2001-02-14 2004-06-24 ラート・マティアス 細胞の生体エネルギー代謝に関与する生化学的化合物の組成物及びそれの使用法
RU2216742C2 (ru) * 2002-01-11 2003-11-20 Потин Владимир Всеволодович Способ количественного определения концентрации антител, специфичных к антигенам стероид-продуцирующих клеток человека, в биологических жидкостях человека, содержащих специфичные антитела
WO2006070432A2 (en) 2004-12-30 2006-07-06 Vito Michele Fazio Anti-tumoral immunogenic peptides and vaccine thereof
CA2733672C (en) 2007-08-16 2018-09-11 The Royal Institution For The Advancement Of Learning/Mcgill University Tumor cell-derived microvesicles
US20100255514A1 (en) 2007-08-16 2010-10-07 The Royal Institution For The Advancement Of Learning/Mcgill University Tumor cell-derived microvesicles
EP3167898A1 (en) 2015-11-11 2017-05-17 IEO - Istituto Europeo di Oncologia Srl Method for obtaining tumor peptides and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172686A (da) * 1985-04-22 1986-10-23 Hybritech Inc Antigen opnaaet ud fra humant vaev, fremgangsmaade til under anvendelse af antigenet at fremstille monoklonale antistoffer til diagnose og behandling af cancer, fremgangsmaade til paavisning af cancer, samt antistoffer mod antigenet
ES8800604A1 (es) * 1985-04-22 1987-11-16 Hybritech Inc Un metodo para producir anticuerpos monoclonales
IT1206250B (it) * 1987-02-18 1989-04-14 Ist Farmacoterapico It Spa Stiche umane e relativi prodotti metodo per l'estrazione di antigeni di membrana aventi proprieta' immunogene a partire da cellule neopla-
RU2077725C1 (ru) * 1992-03-05 1997-04-20 Любовь Львовна Сольская Способ обнаружения раковоэмбрионального антигена при помощи специального антительного диагностикума

Also Published As

Publication number Publication date
RU2141969C1 (ru) 1999-11-27
EP0649433A1 (en) 1995-04-26
KR100237250B1 (ko) 2000-01-15
US5877294A (en) 1999-03-02
DE69315341T2 (de) 1999-03-18
CA2139518A1 (en) 1994-01-20
KR950702207A (ko) 1995-06-19
AU4582393A (en) 1994-01-31
DK0649433T3 (da) 1998-07-27
JPH07508749A (ja) 1995-09-28
RU94046337A (ru) 1996-10-27
EP0649433B1 (en) 1997-11-19
AU680198B2 (en) 1997-07-24
ATE160359T1 (de) 1997-12-15
US5747643A (en) 1998-05-05
WO1994001458A1 (en) 1994-01-20
US5759792A (en) 1998-06-02
ES2111757T3 (es) 1998-03-16
DE69315341D1 (de) 1998-01-02
ITRM920506A0 (it) 1992-07-03
BR9306663A (pt) 1998-12-08
JP2958118B2 (ja) 1999-10-06
CA2139518C (en) 2003-09-23
ITRM920506A1 (it) 1994-01-03

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960724