IT1265023B1 - Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche - Google Patents

Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Info

Publication number
IT1265023B1
IT1265023B1 IT93MI000748A ITMI930748A IT1265023B1 IT 1265023 B1 IT1265023 B1 IT 1265023B1 IT 93MI000748 A IT93MI000748 A IT 93MI000748A IT MI930748 A ITMI930748 A IT MI930748A IT 1265023 B1 IT1265023 B1 IT 1265023B1
Authority
IT
Italy
Prior art keywords
prophylactic
therapeutic
preparation
diagnostic applications
thrombin inhibitors
Prior art date
Application number
IT93MI000748A
Other languages
English (en)
Inventor
Rosa Alfredo De
Armando Rossi
Original Assignee
Dev Biotechnological Processes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dev Biotechnological Processes filed Critical Dev Biotechnological Processes
Priority to IT93MI000748A priority Critical patent/IT1265023B1/it
Publication of ITMI930748A0 publication Critical patent/ITMI930748A0/it
Priority to PCT/EP1994/001144 priority patent/WO1994024156A1/en
Priority to CA002160537A priority patent/CA2160537A1/en
Priority to AU65683/94A priority patent/AU6568394A/en
Priority to US08/532,567 priority patent/US5723576A/en
Priority to JP6522738A priority patent/JPH08512020A/ja
Priority to EP94913591A priority patent/EP0804470A1/en
Publication of ITMI930748A1 publication Critical patent/ITMI930748A1/it
Application granted granted Critical
Publication of IT1265023B1 publication Critical patent/IT1265023B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT93MI000748A 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche IT1265023B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche
PCT/EP1994/001144 WO1994024156A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
CA002160537A CA2160537A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical prophylactic and diagnostic applications
AU65683/94A AU6568394A (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
US08/532,567 US5723576A (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
JP6522738A JPH08512020A (ja) 1993-04-16 1994-04-13 トロンビン阻害因子、その製造および治療、予防および診断用途への応用
EP94913591A EP0804470A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Publications (3)

Publication Number Publication Date
ITMI930748A0 ITMI930748A0 (it) 1993-04-16
ITMI930748A1 ITMI930748A1 (it) 1994-10-16
IT1265023B1 true IT1265023B1 (it) 1996-10-28

Family

ID=11365770

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Country Status (7)

Country Link
US (1) US5723576A (it)
EP (1) EP0804470A1 (it)
JP (1) JPH08512020A (it)
AU (1) AU6568394A (it)
CA (1) CA2160537A1 (it)
IT (1) IT1265023B1 (it)
WO (1) WO1994024156A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6809076B2 (en) * 2000-03-20 2004-10-26 Abbott Gmbh & Co. Kg Use of anticoagulant agents in the extracorporeal treatment of blood
DE10330900B4 (de) * 2003-07-01 2006-09-14 Leibniz-Institut Für Polymerforschung Dresden E.V. Biomaterial mit einem modularen Beschichtungssystem zur Anwendung in Medizinprodukten mit direktem Blutkontakt
CN101094867B (zh) 2004-10-19 2011-08-24 隆萨股份公司 用于固相肽合成的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256559A (en) * 1988-03-04 1993-10-26 Biogen, Inc. Methods and compositions for inhibiting platelet aggregation
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
JP2669510B2 (ja) * 1990-06-15 1997-10-29 ナショナル・リサーチ・カウンシル・オブ カナダ ヒルジンのアミノ酸配列に基づくトロンビン阻害剤

Also Published As

Publication number Publication date
ITMI930748A1 (it) 1994-10-16
EP0804470A1 (en) 1997-11-05
WO1994024156A1 (en) 1994-10-27
AU6568394A (en) 1994-11-08
JPH08512020A (ja) 1996-12-17
CA2160537A1 (en) 1994-10-27
ITMI930748A0 (it) 1993-04-16
US5723576A (en) 1998-03-03

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970324