ITMI930748A1 - Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche - Google Patents

Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Info

Publication number
ITMI930748A1
ITMI930748A1 IT000748A ITMI930748A ITMI930748A1 IT MI930748 A1 ITMI930748 A1 IT MI930748A1 IT 000748 A IT000748 A IT 000748A IT MI930748 A ITMI930748 A IT MI930748A IT MI930748 A1 ITMI930748 A1 IT MI930748A1
Authority
IT
Italy
Prior art keywords
profilactic
therapeutic
preparation
diagnostic applications
thrombin inhibitors
Prior art date
Application number
IT000748A
Other languages
English (en)
Inventor
Rosa Alfredo De
Armando Rossi
Original Assignee
Dev Biotechnological Processes S N C Di P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dev Biotechnological Processes S N C Di P filed Critical Dev Biotechnological Processes S N C Di P
Priority to IT93MI000748A priority Critical patent/IT1265023B1/it
Publication of ITMI930748A0 publication Critical patent/ITMI930748A0/it
Priority to JP6522738A priority patent/JPH08512020A/ja
Priority to AU65683/94A priority patent/AU6568394A/en
Priority to US08/532,567 priority patent/US5723576A/en
Priority to EP94913591A priority patent/EP0804470A1/en
Priority to CA002160537A priority patent/CA2160537A1/en
Priority to PCT/EP1994/001144 priority patent/WO1994024156A1/en
Publication of ITMI930748A1 publication Critical patent/ITMI930748A1/it
Application granted granted Critical
Publication of IT1265023B1 publication Critical patent/IT1265023B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT93MI000748A 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche IT1265023B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche
JP6522738A JPH08512020A (ja) 1993-04-16 1994-04-13 トロンビン阻害因子、その製造および治療、予防および診断用途への応用
AU65683/94A AU6568394A (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
US08/532,567 US5723576A (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
EP94913591A EP0804470A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications
CA002160537A CA2160537A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical prophylactic and diagnostic applications
PCT/EP1994/001144 WO1994024156A1 (en) 1993-04-16 1994-04-13 Thrombin inhibitors, the preparation thereof and the use thereof for therapeutical, prophylactic and diagnostic applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Publications (3)

Publication Number Publication Date
ITMI930748A0 ITMI930748A0 (it) 1993-04-16
ITMI930748A1 true ITMI930748A1 (it) 1994-10-16
IT1265023B1 IT1265023B1 (it) 1996-10-28

Family

ID=11365770

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI000748A IT1265023B1 (it) 1993-04-16 1993-04-16 Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche

Country Status (7)

Country Link
US (1) US5723576A (it)
EP (1) EP0804470A1 (it)
JP (1) JPH08512020A (it)
AU (1) AU6568394A (it)
CA (1) CA2160537A1 (it)
IT (1) IT1265023B1 (it)
WO (1) WO1994024156A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6809076B2 (en) * 2000-03-20 2004-10-26 Abbott Gmbh & Co. Kg Use of anticoagulant agents in the extracorporeal treatment of blood
DE10330900B4 (de) * 2003-07-01 2006-09-14 Leibniz-Institut Für Polymerforschung Dresden E.V. Biomaterial mit einem modularen Beschichtungssystem zur Anwendung in Medizinprodukten mit direktem Blutkontakt
PT1737889E (pt) 2004-10-19 2010-12-13 Lonza Ag Método para síntese de péptidos em fase sólida

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256559A (en) * 1988-03-04 1993-10-26 Biogen, Inc. Methods and compositions for inhibiting platelet aggregation
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
ATE160356T1 (de) * 1990-06-15 1997-12-15 Ca Nat Research Council Thrombin-inhibitoren mit einer hirudin-ähnlichen sequenz

Also Published As

Publication number Publication date
US5723576A (en) 1998-03-03
EP0804470A1 (en) 1997-11-05
WO1994024156A1 (en) 1994-10-27
CA2160537A1 (en) 1994-10-27
JPH08512020A (ja) 1996-12-17
ITMI930748A0 (it) 1993-04-16
AU6568394A (en) 1994-11-08
IT1265023B1 (it) 1996-10-28

Similar Documents

Publication Publication Date Title
FI965039A7 (fi) Uusia trombiini-inhibiittoreita, niiden valmistus ja käyttö
EE04500B1 (et) Trombiini inhibiitorid, nende saamine ja kasutamine
IT8848347A0 (it) Inibitori idrofili della renina, loro preparazione e loro impiegocome medicamenti
FI941378L (fi) Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
FI971412A7 (fi) Peptididyyliyhdisteet ja niiden terapeuttinen käyttö metalloproteaasie n estäjinä
ITRM920412A1 (it) Eteroprostanoidi, procedimento per la loro preparazione e loro impiego terapeutico.
NO971811D0 (no) Bicykliske tetrahydropyrazolopyridiner og deres anvendelse som legemidler
BR9707812A (pt) Composto composto farmacêutica e uso do composto
DK1114821T3 (da) Benzopyraner og disses anvendelse som terapeutiske midler
FI941068A7 (fi) Bentsoksatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI940425A7 (fi) Modifioidut oligodeoksiribonukleotidit, niiden valmistus ja niiden terapeuttinen käyttö
FI930716A7 (fi) Uusia aryylikarbonyyliaminoalkyylidihydro-oksopyridiinejä, niiden valmistus ja käyttö
FI955679L (fi) Piperidiinijohdannaisia, niiden valmistus ja käyttö
ITMI930748A1 (it) Inibitori della trombina, loro preparazione ed uso per applicazioni terapeutiche, profilattiche e diagnostiche
FI956251L (fi) 1-okso-2-(fenyylisulfonyyliamino)pentyylipiperidiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI964446L (fi) Uusia tetrapeptidejä, niiden valmistus ja käyttö
FI941214A7 (fi) Bentsimidatsolin johdannaisia, niiden valmistus ja käyttö
IT1217177B (it) Palmitoil-fruttosio-1,6-difosfato,suo uso terapeutico e relativi metodi di preparazione
FI942265L (fi) 2-aminopyratsin-5-karboksamidijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI952855A7 (fi) Uudet triatsolokinatsoliinit, niiden valmistus ja käyttö
IT8919801A0 (it) Gel di antracicline e loro uso terapeutico.
IT8909564A0 (it) 8-fluoro-antracicline, relativi procedimenti di fabbricazione e loro uso
ITMI922216A1 (it) Nitrobenzoilalanine, procedimento per la loro preparazione, loro uso come agenti terapeutici e composizioni farmaceutiche che le contengono
KR950010930U (ko) 쑥뜸구
IT8822834A0 (it) Nuove perfluoroalchilsolfonil-ossalil-diammidi e -diidrazidi, procedimento per la loro preparazione e loro impiego

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970324