IT1269578B - Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base. - Google Patents

Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.

Info

Publication number
IT1269578B
IT1269578B ITMI940790A ITMI940790A IT1269578B IT 1269578 B IT1269578 B IT 1269578B IT MI940790 A ITMI940790 A IT MI940790A IT MI940790 A ITMI940790 A IT MI940790A IT 1269578 B IT1269578 B IT 1269578B
Authority
IT
Italy
Prior art keywords
base
cyclodestrine
inclusion complexes
acid type
high solubility
Prior art date
Application number
ITMI940790A
Other languages
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Canale Maurizio Del
Enrico Redenti
Daniela Acerbi
Massimo Pasini
Josef Sjeitli
Maria Vikmon
Eva Fenyvesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ITMI940790A0 publication Critical patent/ITMI940790A0/it
Priority to ITMI940790A priority Critical patent/IT1269578B/it
Priority to PCT/EP1995/001407 priority patent/WO1995028965A1/en
Priority to HK98114995.9A priority patent/HK1013627B/en
Priority to DE69518070T priority patent/DE69518070T2/de
Priority to EP95916656A priority patent/EP0756493B1/en
Priority to AU23076/95A priority patent/AU2307695A/en
Priority to ES95916656T priority patent/ES2148512T3/es
Priority to AT95916656T priority patent/ATE194777T1/de
Priority to US08/722,220 priority patent/US5773029A/en
Priority to CA002188388A priority patent/CA2188388A1/en
Priority to PT95916656T priority patent/PT756493E/pt
Priority to IL11345095A priority patent/IL113450A/xx
Priority to ZA953206A priority patent/ZA953206B/xx
Publication of ITMI940790A1 publication Critical patent/ITMI940790A1/it
Application granted granted Critical
Publication of IT1269578B publication Critical patent/IT1269578B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ITMI940790A 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base. IT1269578B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ITMI940790A IT1269578B (it) 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.
ES95916656T ES2148512T3 (es) 1994-04-22 1995-04-13 Complejos de inclusion multicomponentes de alta solubilidad que constan de una sustancia farmaceutica acidica, una ciclodextrina y una base.
US08/722,220 US5773029A (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
DE69518070T DE69518070T2 (de) 1994-04-22 1995-04-13 Mehrfachkomponenten-inklusionskomplexe enthaltend einen sauren arzneistoff, ein zyklodextrin und eine base
EP95916656A EP0756493B1 (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
AU23076/95A AU2307695A (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
PCT/EP1995/001407 WO1995028965A1 (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
AT95916656T ATE194777T1 (de) 1994-04-22 1995-04-13 Mehrfachkomponenten-inklusionskomplexe enthaltend einen sauren arzneistoff, ein zyklodextrin und eine base
HK98114995.9A HK1013627B (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
CA002188388A CA2188388A1 (en) 1994-04-22 1995-04-13 High solubility multicomponent inclusion complexes consisting of an acidic drug, a cyclodextrin and a base
PT95916656T PT756493E (pt) 1994-04-22 1995-04-13 Complexos de inclusao com componentes multiplos de elevada solubilidade que contem um medicamento acido uma ciclodextrina e uma base
IL11345095A IL113450A (en) 1994-04-22 1995-04-20 Process for the preparation of high solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base and the complexes produced thereby
ZA953206A ZA953206B (en) 1994-04-22 1995-04-20 High solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI940790A IT1269578B (it) 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.

Publications (3)

Publication Number Publication Date
ITMI940790A0 ITMI940790A0 (it) 1994-04-22
ITMI940790A1 ITMI940790A1 (it) 1995-10-22
IT1269578B true IT1269578B (it) 1997-04-08

Family

ID=11368715

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940790A IT1269578B (it) 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.

Country Status (12)

Country Link
US (1) US5773029A (it)
EP (1) EP0756493B1 (it)
AT (1) ATE194777T1 (it)
AU (1) AU2307695A (it)
CA (1) CA2188388A1 (it)
DE (1) DE69518070T2 (it)
ES (1) ES2148512T3 (it)
IL (1) IL113450A (it)
IT (1) IT1269578B (it)
PT (1) PT756493E (it)
WO (1) WO1995028965A1 (it)
ZA (1) ZA953206B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7637296A (en) * 1995-11-14 1997-06-05 Farmarc Nederland Bv Complex of naproxen and beta-cyclodextrin
ATE277641T1 (de) * 1996-05-07 2004-10-15 Pfizer Verfahren zur selektion eines salzes zur herstellung eines inklusionskomplexes
UA57734C2 (uk) 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6939863B2 (en) 2002-01-04 2005-09-06 Wei-Jan Chen Prevention of atherosclerosis and restenosis
CN100553625C (zh) 2002-04-09 2009-10-28 弗拉梅技术公司 活性成分微囊的口服混悬液
SI1374906T1 (sl) * 2002-06-17 2007-10-31 Chiesi Farma Spa Postopek za pripravo inkluzijskih spojin piroksakama: beta-ciklodekstrina
GEP20063996B (en) * 2002-08-20 2006-12-11 Bristol Myers Squibb Co Aripiprazole complex formulation and use thereof
DE10260872B4 (de) * 2002-12-23 2013-09-26 Beiersdorf Ag Verwendung von gelbildendem Polymer, Wasser, Alkohol und Meeresalgenextrakt zur Einstellung von Elastizität und Haftvermögen selbstklebender kosmetischer Polymermatrices
US7993654B2 (en) * 2002-12-23 2011-08-09 Beiersdorf Ag Self-adhesive polymer matrix containing sea algae extract
DE10260873A1 (de) 2002-12-23 2004-07-15 Beiersdorf Ag Selbstklebende Polymermatrix mit einem Gehalt an Meeresalgenextrakt und Glycerin
US20070020578A1 (en) * 2005-07-19 2007-01-25 Scott Robert R Dental curing light having a short wavelength LED and a fluorescing lens for converting wavelength light to curing wavelengths and related method
US20080171687A1 (en) * 2004-09-16 2008-07-17 Abraxis Bioscience, Inc. Compositions And Methods For The Preparation And Administration Of Poorly Water Soluble Drugs
US8772346B2 (en) * 2005-11-09 2014-07-08 Torrent Pharmaceuticals Limited Pharmaceutical composition
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
CN106389307A (zh) 2009-05-29 2017-02-15 锡德克斯药物公司 包含环糊精衍生物的可注射美法仑组合物及其制备和使用方法
CN108210501B (zh) 2016-12-14 2019-03-08 中国人民解放军军事医学科学院毒物药物研究所 一种磺酰脲类药物的注射用药物组合物及其制备方法
WO2022187567A2 (en) * 2021-03-04 2022-09-09 Biogen Chesapeake Llc Low-sorbing glyburide formulation and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
IT1224835B (it) * 1987-12-22 1990-10-24 Glaxo Group Ltd Formulazioni acquose contenenti un derivato di acido piperidinciclopentileptenoico e procedimento per prepararle
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina

Also Published As

Publication number Publication date
EP0756493B1 (en) 2000-07-19
IL113450A0 (en) 1995-07-31
ATE194777T1 (de) 2000-08-15
EP0756493A1 (en) 1997-02-05
PT756493E (pt) 2000-10-31
ITMI940790A1 (it) 1995-10-22
DE69518070D1 (de) 2000-08-24
ZA953206B (en) 1996-01-03
ES2148512T3 (es) 2000-10-16
US5773029A (en) 1998-06-30
ITMI940790A0 (it) 1994-04-22
DE69518070T2 (de) 2001-01-11
HK1013627A1 (en) 1999-09-03
WO1995028965A1 (en) 1995-11-02
CA2188388A1 (en) 1995-11-02
IL113450A (en) 1999-05-09
AU2307695A (en) 1995-11-16

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970324