IT1271463B - Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn. - Google Patents
Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn.Info
- Publication number
- IT1271463B IT1271463B ITFI930260A ITFI930260A IT1271463B IT 1271463 B IT1271463 B IT 1271463B IT FI930260 A ITFI930260 A IT FI930260A IT FI930260 A ITFI930260 A IT FI930260A IT 1271463 B IT1271463 B IT 1271463B
- Authority
- IT
- Italy
- Prior art keywords
- alfal
- cohn
- fraction
- extraction
- purification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000000605 extraction Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 229940024142 alpha 1-antitrypsin Drugs 0.000 abstract 1
- 238000004191 hydrophobic interaction chromatography Methods 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 230000007928 solubilization Effects 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI930260A IT1271463B (it) | 1993-12-16 | 1993-12-16 | Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn. |
| DE69409390T DE69409390T2 (de) | 1993-12-16 | 1994-12-16 | Verfahren zur Extraktion und Reinigung von Alpha-1-Antitrypsin (alpha 1-pI) aus Cohnischer Fraktion IV-1 |
| AT94119902T ATE164594T1 (de) | 1993-12-16 | 1994-12-16 | Verfahren zur extraktion und reinigung von alpha- 1-antitrypsin (alpha 1-pi) aus cohnischer fraktion iv-1 |
| ES94119902T ES2117197T3 (es) | 1993-12-16 | 1994-12-16 | Procedimiento para la extraccion y purificacion de alfa1-antitripsina (alfa1-pi) a partir de la fraccion de cohn iv-1. |
| EP94119902A EP0717049B1 (en) | 1993-12-16 | 1994-12-16 | Process for the extraction and purification of alfa1-antitrypsin (alfa1-pI) from cohn IV-1 fraction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI930260A IT1271463B (it) | 1993-12-16 | 1993-12-16 | Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITFI930260A0 ITFI930260A0 (it) | 1993-12-16 |
| ITFI930260A1 ITFI930260A1 (it) | 1995-06-16 |
| IT1271463B true IT1271463B (it) | 1997-05-28 |
Family
ID=11350681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITFI930260A IT1271463B (it) | 1993-12-16 | 1993-12-16 | Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0717049B1 (it) |
| AT (1) | ATE164594T1 (it) |
| DE (1) | DE69409390T2 (it) |
| ES (1) | ES2117197T3 (it) |
| IT (1) | IT1271463B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2318732A (en) | 1996-11-01 | 1998-05-06 | Johnson & Johnson Medical | Wound healing compositions containing alpha-1-antitrypsin |
| DE19932782A1 (de) * | 1999-07-14 | 2001-01-18 | Biotest Pharma Gmbh | Verfahren zur chromatographischen Fraktionierung von Plasma oder Serum, so erhaltene Präparate und deren Verwendung |
| US7777006B2 (en) | 2002-12-31 | 2010-08-17 | Csl Behring L.L.C. | Method for purification of alpha-1-antitrypsin |
| CN111454351A (zh) * | 2019-06-17 | 2020-07-28 | 国药集团上海血液制品有限公司 | 一种α1-抗胰蛋白酶的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2610633B1 (fr) * | 1987-02-05 | 1992-09-18 | Lille Transfusion Sanguine | Procede d'obtention d'un concentre d'a 1-antitrypsine a partir de plasma humain et son utilisation a titre de medicament |
-
1993
- 1993-12-16 IT ITFI930260A patent/IT1271463B/it active IP Right Grant
-
1994
- 1994-12-16 ES ES94119902T patent/ES2117197T3/es not_active Expired - Lifetime
- 1994-12-16 EP EP94119902A patent/EP0717049B1/en not_active Expired - Lifetime
- 1994-12-16 AT AT94119902T patent/ATE164594T1/de active
- 1994-12-16 DE DE69409390T patent/DE69409390T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0717049B1 (en) | 1998-04-01 |
| DE69409390T2 (de) | 1998-10-29 |
| DE69409390D1 (de) | 1998-05-07 |
| ITFI930260A1 (it) | 1995-06-16 |
| EP0717049A1 (en) | 1996-06-19 |
| ES2117197T3 (es) | 1998-08-01 |
| ITFI930260A0 (it) | 1993-12-16 |
| ATE164594T1 (de) | 1998-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961230 |