IT1276167B1 - Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni - Google Patents

Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni

Info

Publication number
IT1276167B1
IT1276167B1 IT95MI002446A ITMI952446A IT1276167B1 IT 1276167 B1 IT1276167 B1 IT 1276167B1 IT 95MI002446 A IT95MI002446 A IT 95MI002446A IT MI952446 A ITMI952446 A IT MI952446A IT 1276167 B1 IT1276167 B1 IT 1276167B1
Authority
IT
Italy
Prior art keywords
preparation
pct
quinossalin
imidazo
alpha
Prior art date
Application number
IT95MI002446A
Other languages
English (en)
Inventor
Stefano Ceccarelli
Sergio Zanarella
Maria Altobelli
Alessandro Alessandra D
Original Assignee
Foscama Biomed Chim Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma
Publication of ITMI952446A0 publication Critical patent/ITMI952446A0/it
Priority to IT95MI002446A priority Critical patent/IT1276167B1/it
Priority to AT96937458T priority patent/ATE194347T1/de
Priority to PCT/IB1996/001291 priority patent/WO1997019079A1/en
Priority to ES96937458T priority patent/ES2149504T3/es
Priority to EP96937458A priority patent/EP0865442B1/en
Priority to PT96937458T priority patent/PT865442E/pt
Priority to DE69609192T priority patent/DE69609192T2/de
Priority to US09/068,515 priority patent/US6124287A/en
Publication of ITMI952446A1 publication Critical patent/ITMI952446A1/it
Application granted granted Critical
Publication of IT1276167B1 publication Critical patent/IT1276167B1/it
Priority to GR20000402042T priority patent/GR3034354T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT95MI002446A 1995-11-24 1995-11-24 Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni IT1276167B1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT95MI002446A IT1276167B1 (it) 1995-11-24 1995-11-24 Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni
EP96937458A EP0865442B1 (en) 1995-11-24 1996-11-22 IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF
PCT/IB1996/001291 WO1997019079A1 (en) 1995-11-24 1996-11-22 IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF
ES96937458T ES2149504T3 (es) 1995-11-24 1996-11-22 Imidazo(1,2-a)quinoxalin-4-aminas activas como antagonistas de la adenosina, procedimiento para su preparacion y composiciones farmaceuticas de las mismas.
AT96937458T ATE194347T1 (de) 1995-11-24 1996-11-22 Imidazo(1,2-a)quinoxalin-4-amine als adenosin- antagonisten, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
PT96937458T PT865442E (pt) 1995-11-24 1996-11-22 Imidazo¬1,2-a|quinoxalin-4-aminas activas como antagonistas de adenosina processo para a sua preparacao e suas composicoes farmaceuticas
DE69609192T DE69609192T2 (de) 1995-11-24 1996-11-22 Imidazo(1,2-a)quinoxalin-4-amine als adenosin-antagonisten, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
US09/068,515 US6124287A (en) 1995-11-24 1996-11-22 Imidazo[1,2-a]quinoxalin-4-amines active as adenosine antagonists, process for their preparation and pharmaceutical compositions thereof
GR20000402042T GR3034354T3 (en) 1995-11-24 2000-09-06 IMIDAZO 1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002446A IT1276167B1 (it) 1995-11-24 1995-11-24 Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni

Publications (3)

Publication Number Publication Date
ITMI952446A0 ITMI952446A0 (it) 1995-11-24
ITMI952446A1 ITMI952446A1 (it) 1997-05-24
IT1276167B1 true IT1276167B1 (it) 1997-10-27

Family

ID=11372590

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI002446A IT1276167B1 (it) 1995-11-24 1995-11-24 Imidazo(1,2-alfa)chinossalin-4-ammine attivi come antagonisti adenosinici,procedimento per la loro preparazione e loro composizioni

Country Status (9)

Country Link
US (1) US6124287A (it)
EP (1) EP0865442B1 (it)
AT (1) ATE194347T1 (it)
DE (1) DE69609192T2 (it)
ES (1) ES2149504T3 (it)
GR (1) GR3034354T3 (it)
IT (1) IT1276167B1 (it)
PT (1) PT865442E (it)
WO (1) WO1997019079A1 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235740B1 (en) 1997-08-25 2001-05-22 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en) 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
DE69940808D1 (de) * 1998-03-04 2009-06-10 Bristol Myers Squibb Co Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren
AU1182702A (en) 2000-10-03 2002-04-15 Bristol Myers Squibb Co Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same
US6869956B2 (en) 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
CN100386326C (zh) * 2003-10-22 2008-05-07 中国人民解放军军事医学科学院毒物药物研究所 1-羟甲基咪唑并[1，2-a]喹喔啉化合物及其应用
ATE539079T1 (de) * 2006-03-23 2012-01-15 Novartis Ag Imidazochinoxalinverbindungen als immunmodulatoren
DE102006039912A1 (de) * 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
WO2008072779A1 (ja) * 2006-12-13 2008-06-19 Aska Pharmaceutical Co., Ltd. キノキサリン誘導体
EP1972629A1 (en) * 2007-03-23 2008-09-24 Mutabilis SA New imidazolo-heteroaryl derivatives with antibacterial properties
ITMI20072230A1 (it) * 2007-11-23 2009-05-24 Campagnolo Srl Dispositivo di comando per bicicletta con manubrio ricurvo
WO2017037604A1 (en) * 2015-08-28 2017-03-09 Bheema Rao Paraselli Novel fyn kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229452A (en) * 1977-01-07 1980-10-21 Westwood Pharmaceuticals, Inc. Treatment of inflammatory disorders with 4-trifluoromethylimidazo[1,2-a]quinoxaline
US4780464A (en) * 1986-12-08 1988-10-25 Warner-Lambert Company (1,2,4)triazolo(4,3-a)quinoxaline-4-amines
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands
JPH08508271A (ja) * 1993-03-31 1996-09-03 ビーエーエスエフ アクチエンゲゼルシャフト Ｅａａ拮抗体としてのイミダゾロキノキサリノン誘導体

Also Published As

Publication number Publication date
PT865442E (pt) 2000-10-31
EP0865442B1 (en) 2000-07-05
ES2149504T3 (es) 2000-11-01
ITMI952446A0 (it) 1995-11-24
GR3034354T3 (en) 2000-12-29
ITMI952446A1 (it) 1997-05-24
US6124287A (en) 2000-09-26
WO1997019079A1 (en) 1997-05-29
DE69609192D1 (de) 2000-08-10
DE69609192T2 (de) 2001-03-22
ATE194347T1 (de) 2000-07-15
EP0865442A1 (en) 1998-09-23

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Legal Events

Date Code Title Description
0001 Granted