IT1283149B1 - Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato - Google Patents

Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato

Info

Publication number
IT1283149B1
IT1283149B1 IT96MI001449A ITMI961449A IT1283149B1 IT 1283149 B1 IT1283149 B1 IT 1283149B1 IT 96MI001449 A IT96MI001449 A IT 96MI001449A IT MI961449 A ITMI961449 A IT MI961449A IT 1283149 B1 IT1283149 B1 IT 1283149B1
Authority
IT
Italy
Prior art keywords
acetylpartricine
dimethylaminoethylamide
cholesterol
dimethylamino
complexes
Prior art date
Application number
IT96MI001449A
Other languages
English (en)
Inventor
Tiberio Bruzzese
Giovanni Mozzi
Original Assignee
Prodotti Antibiotici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodotti Antibiotici Spa filed Critical Prodotti Antibiotici Spa
Priority to IT96MI001449A priority Critical patent/IT1283149B1/it
Publication of ITMI961449A0 publication Critical patent/ITMI961449A0/it
Priority to PCT/EP1997/003465 priority patent/WO1998002168A1/en
Priority to US09/147,509 priority patent/US6143726A/en
Publication of ITMI961449A1 publication Critical patent/ITMI961449A1/it
Application granted granted Critical
Publication of IT1283149B1 publication Critical patent/IT1283149B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT96MI001449A 1996-07-12 1996-07-12 Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato IT1283149B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT96MI001449A IT1283149B1 (it) 1996-07-12 1996-07-12 Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato
PCT/EP1997/003465 WO1998002168A1 (en) 1996-07-12 1997-07-02 Complexes of n'-dimethylaminoacetylpartricin a dimethylaminoethylamide, or the salts thereof, and cholesterol 3-sulphate
US09/147,509 US6143726A (en) 1996-07-12 1997-07-02 Complexes of N'-dimethylaminoacetylpartricin A dimethylaminoethylamide, or the salts thereof, and cholesterol 3-sulphate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001449A IT1283149B1 (it) 1996-07-12 1996-07-12 Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato

Publications (3)

Publication Number Publication Date
ITMI961449A0 ITMI961449A0 (it) 1996-07-12
ITMI961449A1 ITMI961449A1 (it) 1998-01-12
IT1283149B1 true IT1283149B1 (it) 1998-04-07

Family

ID=11374579

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI001449A IT1283149B1 (it) 1996-07-12 1996-07-12 Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato

Country Status (3)

Country Link
US (1) US6143726A (it)
IT (1) IT1283149B1 (it)
WO (1) WO1998002168A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1301807B1 (it) * 1998-06-25 2000-07-07 Tiberio Bruzzese Formulazioni farmaceutiche iniettabili di derivati della partricina.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1463348A (en) * 1974-09-03 1977-02-02 Prodotti Antibiotici Spa Water-solubilised compositions
US4822777A (en) * 1987-02-27 1989-04-18 Liposome Technology, Inc. Amphotericin B/cholesterol sulfate composition
IT1237772B (it) * 1989-11-16 1993-06-17 Tiberio Bruzzese Derivati di macrolidi polienici.
IT1243404B (it) * 1990-12-03 1994-06-10 Prodotti Antibiotici Spa Derivati della partricina

Also Published As

Publication number Publication date
US6143726A (en) 2000-11-07
ITMI961449A1 (it) 1998-01-12
ITMI961449A0 (it) 1996-07-12
WO1998002168A1 (en) 1998-01-22

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Legal Events

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0001 Granted