IT1285404B1 - Procedimento per accrescere il flusso per elettrotrasporto di polipeptidi - Google Patents

Procedimento per accrescere il flusso per elettrotrasporto di polipeptidi

Info

Publication number
IT1285404B1
IT1285404B1 IT96TO000495A ITTO960495A IT1285404B1 IT 1285404 B1 IT1285404 B1 IT 1285404B1 IT 96TO000495 A IT96TO000495 A IT 96TO000495A IT TO960495 A ITTO960495 A IT TO960495A IT 1285404 B1 IT1285404 B1 IT 1285404B1
Authority
IT
Italy
Prior art keywords
electrotransportation
polypeptides
procedure
increasing
flow
Prior art date
Application number
IT96TO000495A
Other languages
English (en)
Inventor
Leslie A Holladay
Kevin R Oldenburg
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ITTO960495A0 publication Critical patent/ITTO960495A0/it
Publication of ITTO960495A1 publication Critical patent/ITTO960495A1/it
Application granted granted Critical
Publication of IT1285404B1 publication Critical patent/IT1285404B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT96TO000495A 1995-06-06 1996-06-05 Procedimento per accrescere il flusso per elettrotrasporto di polipeptidi IT1285404B1 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/468,275 US5747453A (en) 1995-06-06 1995-06-06 Method for increasing the electrotransport flux of polypeptides

Publications (3)

Publication Number Publication Date
ITTO960495A0 ITTO960495A0 (it) 1996-06-05
ITTO960495A1 ITTO960495A1 (it) 1997-12-05
IT1285404B1 true IT1285404B1 (it) 1998-06-03

Family

ID=23859150

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96TO000495A IT1285404B1 (it) 1995-06-06 1996-06-05 Procedimento per accrescere il flusso per elettrotrasporto di polipeptidi

Country Status (13)

Country Link
US (2) US5747453A (it)
JP (1) JPH11507634A (it)
AU (1) AU6264296A (it)
BE (1) BE1009752A5 (it)
BR (1) BR9609148A (it)
CA (1) CA2220060A1 (it)
DE (1) DE19681438B4 (it)
FR (1) FR2735133B1 (it)
GB (1) GB2316083B (it)
IE (1) IE960414A1 (it)
IT (1) IT1285404B1 (it)
NL (1) NL1003284C2 (it)
WO (1) WO1996039423A2 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6333189B1 (en) 1996-06-06 2001-12-25 Alza Corporation Method of making an electrotransport device
EP0922467A3 (en) * 1997-12-12 2000-05-24 Takeda Chemical Industries, Ltd. Iontophoretic drug delivery
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) * 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8465425B2 (en) * 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
EP1532261B1 (en) 2002-05-24 2010-02-10 Medtronic, Inc. Methods and dna constructs for high yield production of polypeptides
WO2003099854A2 (en) * 2002-05-24 2003-12-04 Nps Allelix Corp. Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
EP1554302A4 (en) * 2002-05-24 2006-05-03 Restoragen Inc METHOD AND DNA CONSTRUCTS FOR THE PRODUCTION OF POLYPEPTIDES HAVING A HIGH LEVEL
HRP20120315T1 (hr) * 2003-11-21 2012-05-31 Nps Pharmaceuticals Proizvodnja peptida 2 nalik glukagonu i analoga
CN101094867B (zh) 2004-10-19 2011-08-24 隆萨股份公司 用于固相肽合成的方法
JP2009522288A (ja) * 2005-12-28 2009-06-11 アルザ コーポレイション 安定な治療剤形

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
US4382529A (en) * 1980-12-15 1983-05-10 Drdlik Frank J Sanitary dispensing closure
CA1231306A (en) * 1983-03-03 1988-01-12 Erich Hochuli Purification of interferon
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
AU609769B2 (en) * 1987-02-10 1991-05-09 Drug Delivery Systems Inc. Electrolytic transdermal delivery of proteins
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
WO1991000870A1 (en) * 1989-07-10 1991-01-24 The Upjohn Company Somatotropin analogs
US5516512A (en) * 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
NZ237202A (en) * 1990-02-23 1994-01-26 Bristol Myers Squibb Co Composition containing beta-lactam antibiotic and cationic oligopeptide
USH1160H (en) * 1990-11-26 1993-04-06 Iontophoretic delivery of peptides
DK10191D0 (da) * 1991-01-22 1991-01-22 Novo Nordisk As Hidtil ukendte peptider
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5312326A (en) * 1992-06-02 1994-05-17 Alza Corporation Iontophoretic drug delivery apparatus
WO1993025197A1 (en) * 1992-06-12 1993-12-23 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
US5814603A (en) * 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
SK155694A3 (en) * 1992-06-15 1995-05-10 Pfizer Glucagon-like peptide, insulinotropin derivatives, method of their preparation, pharmaceutical agent containing and using these matters
ATE211655T1 (de) * 1993-09-22 2002-01-15 Hisamitsu Pharmaceutical Co Iontophoresematrix
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
DE4404168A1 (de) * 1994-02-10 1995-08-17 Hoechst Ag Hirudinderivate und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
JPH11507634A (ja) 1999-07-06
ITTO960495A0 (it) 1996-06-05
FR2735133B1 (fr) 1998-02-13
DE19681438T1 (de) 1998-07-23
DE19681438B4 (de) 2010-02-04
US5747453A (en) 1998-05-05
IE960414A1 (en) 1996-12-11
CA2220060A1 (en) 1996-12-12
BE1009752A5 (fr) 1997-07-01
FR2735133A1 (fr) 1996-12-13
AU6264296A (en) 1996-12-24
NL1003284C2 (nl) 1997-03-20
WO1996039423A3 (en) 1997-01-30
GB9725980D0 (en) 1998-02-04
US6313092B1 (en) 2001-11-06
BR9609148A (pt) 1999-02-23
GB2316083B (en) 2000-01-19
WO1996039423A2 (en) 1996-12-12
ITTO960495A1 (it) 1997-12-05
GB2316083A (en) 1998-02-18
NL1003284A1 (nl) 1996-12-09

Similar Documents

Publication Publication Date Title
IT1276802B1 (it) Procedimento integrato per la produzione di butene-1
FI960519A0 (fi) Uusia yhdisteitä
DK0820276T3 (da) Fremgangsmåde til fremstilling af respirerbare partikler
FI973281L (fi) Menetelmä tiettyjen atsasykloheksapeptidien valmistamiseksi
DE69605614D1 (de) Durchflussregler
DE69606558D1 (de) Am umfang angetriebene durchflusszentrifuge
ITTO960495A0 (it) Procedimento per accrescere il flusso per elettrotrasporto di polipep-tidi.
ID21424A (id) Konfigurasi katup gabungan untuk unit siklus-uap
DK0854999T3 (da) Væskeflowforbindelsesdel
ITTO960496A0 (it) Modificatione di farmaci polipeptidici per accrescere il flusso per e-lettrotrasporto.
IT1272922B (it) Procedimento per la preparazione di composti metallocenici
ITBZ970005U1 (it) Dispositivo per l'applicazione di rivestimenti.
ITMI940317A0 (it) Procedimento per la produzione di gamma-butirrolattone
DE69525744D1 (de) Faltenbälge
ITMI931680A0 (it) Procedimento per la preparazione di alcansolfonammidi
IT1295934B1 (it) Procedimento migliorato per la sintesi di alchilpoliglucosidi
IT1314685B1 (it) Controllore di flusso
IT1277973B1 (it) Procedimento per l'assemblaggio di semilavorati per calze-mutanda
DK0721929T3 (da) Fremgangsmåde til fremstilling af hydroxyalkoxybenzophenoner
DK0863874T3 (da) Fremgangsmåde til fremstilling af dioxoazabicyclohexaner
DE59601357D1 (de) Neue Flüssigformulierungen
ITMI962551A0 (it) Procedimento per la sintesi di 2-idrossi-4-alchilossi benzofenone
DE59600766D1 (de) Flüssigkeitsringverdichter
KR960033664U (ko) 액상물 분무기
EE9900404A (et) Arüülaminotriasolopüridiinide valmistamise meetod

Legal Events

Date Code Title Description
0001 Granted