DK10191D0 - Hidtil ukendte peptider - Google Patents

Hidtil ukendte peptider

Info

Publication number
DK10191D0
DK10191D0 DK010191A DK10191A DK10191D0 DK 10191 D0 DK10191 D0 DK 10191D0 DK 010191 A DK010191 A DK 010191A DK 10191 A DK10191 A DK 10191A DK 10191 D0 DK10191 D0 DK 10191D0
Authority
DK
Denmark
Prior art keywords
molecule
insulin
human insulin
unknown peptides
insulin analogues
Prior art date
Application number
DK010191A
Other languages
English (en)
Inventor
Jens Joergen Veilgaard Brange
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK010191A priority Critical patent/DK10191D0/da
Publication of DK10191D0 publication Critical patent/DK10191D0/da
Priority to EP92903864A priority patent/EP0568594B1/en
Priority to CA002100565A priority patent/CA2100565A1/en
Priority to DE69210011T priority patent/DE69210011T2/de
Priority to AU11902/92A priority patent/AU1190292A/en
Priority to PCT/DK1992/000019 priority patent/WO1992012999A1/en
Priority to JP4503787A priority patent/JPH06506444A/ja
Priority to AT92903864T priority patent/ATE136907T1/de
Priority to US08/301,838 priority patent/US5597796A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK010191A 1991-01-22 1991-01-22 Hidtil ukendte peptider DK10191D0 (da)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider
EP92903864A EP0568594B1 (en) 1991-01-22 1992-01-22 NOVEL INSULIN ANALOGS suited for transdermal application
CA002100565A CA2100565A1 (en) 1991-01-22 1992-01-22 Insulin analogs
DE69210011T DE69210011T2 (de) 1991-01-22 1992-01-22 Neue Insulinanaloge geeignet für die transdermale Anwendung
AU11902/92A AU1190292A (en) 1991-01-22 1992-01-22 Novel insulin analogs
PCT/DK1992/000019 WO1992012999A1 (en) 1991-01-22 1992-01-22 Novel insulin analogs
JP4503787A JPH06506444A (ja) 1991-01-22 1992-01-22 新規インスリン類似体
AT92903864T ATE136907T1 (de) 1991-01-22 1992-01-22 Neue insulinanaloge geeignet für die transdermale anwendung
US08/301,838 US5597796A (en) 1991-01-22 1994-09-07 Transdermal insulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider

Publications (1)

Publication Number Publication Date
DK10191D0 true DK10191D0 (da) 1991-01-22

Family

ID=8089747

Family Applications (1)

Application Number Title Priority Date Filing Date
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider

Country Status (9)

Country Link
US (1) US5597796A (da)
EP (1) EP0568594B1 (da)
JP (1) JPH06506444A (da)
AT (1) ATE136907T1 (da)
AU (1) AU1190292A (da)
CA (1) CA2100565A1 (da)
DE (1) DE69210011T2 (da)
DK (1) DK10191D0 (da)
WO (1) WO1992012999A1 (da)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5747453A (en) * 1995-06-06 1998-05-05 Alza Corporation Method for increasing the electrotransport flux of polypeptides
IT1285405B1 (it) 1995-06-06 1998-06-03 Alza Corp Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto.
EP0861089B1 (en) * 1995-11-13 2002-07-17 Medtronic MiniMed, Inc. Methods and compositions for the delivery of monomeric proteins
US6333189B1 (en) 1996-06-06 2001-12-25 Alza Corporation Method of making an electrotransport device
US5857994A (en) * 1996-10-01 1999-01-12 Becton, Dickinson And Company Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
CA2309955A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Method for decreasing self-association of polypeptides
US6562942B1 (en) * 1999-02-23 2003-05-13 Neurocrine Biosciences, Inc. Methods for treatment of diabetes using peptide analogues of insulin
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
HK1041228A1 (zh) * 1999-02-18 2002-07-05 Biovalve Technologies, Inc. 电活动孔
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
EP1270012A1 (en) * 2001-06-21 2003-01-02 Pfizer Products Inc. Use of pulmonary administration of insulin for treatment of diabetes
JP4033382B2 (ja) * 2002-04-08 2008-01-16 久光製薬株式会社 インスリン投与装置
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
WO2007096332A1 (en) * 2006-02-21 2007-08-30 Novo Nordisk A/S Single-chain insulin analogues and pharmaceutical formulations thereof
WO2007128815A1 (en) * 2006-05-09 2007-11-15 Novo Nordisk A/S Insulin derivative
AU2007247109B2 (en) * 2006-05-09 2012-03-15 Novo Nordisk A/S Insulin derivative
CN101573133B (zh) 2006-07-31 2014-08-27 诺沃-诺迪斯克有限公司 Peg化延长的胰岛素
CN101541830A (zh) * 2006-09-22 2009-09-23 诺沃-诺迪斯克有限公司 蛋白酶抗性的胰岛素类似物
WO2008132224A2 (en) 2007-04-30 2008-11-06 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
JP2009067766A (ja) * 2007-09-12 2009-04-02 Kosumedei Seiyaku Kk 経皮吸収促製剤及びそれを用いた経皮吸収システム
RU2524423C2 (ru) 2008-01-09 2014-07-27 Санофи-Авентис Дойчланд Гмбх Новые производные инсулина с чрезвычайно замедленным профилем время/действие
KR20100111683A (ko) * 2008-01-09 2010-10-15 사노피-아벤티스 도이칠란트 게엠베하 극히 지연된 시간-작용 프로필을 갖는 신규 인슐린 유도체
CN101970477B (zh) 2008-03-14 2014-12-31 诺沃-诺迪斯克有限公司 蛋白酶稳定的胰岛素类似物
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
PH12011502708B1 (en) 2009-07-06 2017-11-10 Sanofi Aventis Deutschland Insulin preparations containing methionine
WO2011003820A1 (de) * 2009-07-06 2011-01-13 Sanofi-Aventis Deutschland Gmbh Hitze- und schüttelstabile insulinzubereitungen
JP5832439B2 (ja) 2009-11-13 2015-12-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト、インスリン及びメチオニンを含む薬学的組成物
SG10201500871TA (en) 2009-11-13 2015-04-29 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
EP2552407A1 (en) 2010-03-31 2013-02-06 Wockhardt Limited Composition comprising insulin and herbal oil for transdermal or transmucosal administration
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病患者の血糖コントロールに使用する組合せ医薬
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN104168911A (zh) * 2012-01-20 2014-11-26 卡斯西部储备大学 谷氨酸-稳定的胰岛素类似物
EP2836508B1 (en) 2012-04-11 2016-06-29 Novo Nordisk A/S Insulin formulations
JP2016516728A (ja) * 2013-03-15 2016-06-09 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎ Ｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ 第２部位インスリン類似体
CA2926701A1 (en) 2013-10-07 2015-04-16 Novo Nordisk A/S Novel derivative of an insulin analogue
GB201321489D0 (en) 2013-12-05 2014-01-22 Chemical & Biopharmaceutical Lab Of Patras S A Biologically active insulin derivatives
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
BR112019004314A2 (pt) 2016-09-06 2019-05-28 Chemical & Biopharmaceutical Laboratories Of Patras S A derivados pró-insulina
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
CA3071686A1 (en) 2017-08-17 2019-02-21 Novo Nordisk A/S Novel acylated insulin analogues and uses thereof
EP3756679A1 (en) 2019-06-28 2020-12-30 Université de Genève Compositions for use in the treatment of insulin deficiency conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
WO1990001038A1 (en) * 1988-07-20 1990-02-08 Nordisk Gentofte A/S Human insulin analogs and preparations containing them
HUT56857A (en) * 1988-12-23 1991-10-28 Novo Nordisk As Human insulin analogues
IL93282A (en) * 1989-02-09 1995-08-31 Lilly Co Eli Insulin analogues
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain

Also Published As

Publication number Publication date
CA2100565A1 (en) 1992-07-23
US5597796A (en) 1997-01-28
DE69210011T2 (de) 1996-09-05
WO1992012999A1 (en) 1992-08-06
DE69210011D1 (de) 1996-05-23
ATE136907T1 (de) 1996-05-15
EP0568594A1 (en) 1993-11-10
JPH06506444A (ja) 1994-07-21
AU1190292A (en) 1992-08-27
EP0568594B1 (en) 1996-04-17

Similar Documents

Publication Publication Date Title
DE69210011D1 (de) Neue Insulinanaloge geeignet für die transdermale Anwendung
DK642587A (da) Insulinpraeparat
ATA260690A (de) Therapeutische infusionszubereitung auf basis von aminosäurederivaten
ATE73459T1 (de) Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten.
DE3583008D1 (de) Pharmazeutische zusammensetzungen von dihydrocodeine/ibuprofen und verfahren.
DK107086D0 (da) Peptider
DK0439042T3 (da) Anvendelse af farmaceutiske og kosmetiske præparater med blandingsmiceller
HUP9904023A2 (hu) Leptin antagonisták alkalmazása inzulin rezisztencia kezelésére II. típusú cukorbajban
DK395689A (da) Pharmaceutisk tilberedning til behandling af diabetes mellitus
NZ294743A (en) A formulation for administering transdermally a protein or polypeptide such as insulin
EP0994724A4 (en) METHODS AND COMPOSITIONS TO PREVENT THE REPRODUCTION OF HIV-1
LV10720A (lv) Peptidi un farmaceitiska kompozicija uz to bazes
DK0725648T3 (da) Leverspecifikke farmaceutiske aktivstoffer
DK0593450T3 (da) Præparater omfattende omega-conotoxin-peptidderivater og deres anvendelse til behandling af neuronal beskadigelse med relation til iskæmi
DK414389A (da) Farmaceutisk praeparat indeholdende et aminosyrederivat med renin-inhibitorisk virkning
DK395789D0 (da) Anvendelse af alfa-aminoboronsyrederivater til fremstilling af et laegemiddel til terapi eller profylakse af virussygdomme
ATE125706T1 (de) Diphosphonate enthaltende pharmazeutische zusammensetzungen zur behandlung von arthrosis.
MX9703642A (es) Metodos para el tratamiento de esclerosis multiple utilizando analogos de peptido en la posicion 91 de la proteina basica de mielina humana.
PT88539A (pt) Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
DE69004532D1 (de) Topisch anzuwendende Defibrotid enthaltende Arzneizubereitungen.
BG97123A (bg) Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
DK288789D0 (da) Peptider og syreadditionssalte deraf, deres fremstilling og anvendelse
GR3003733T3 (da)
NO890174L (no) Rekombinante interleukin-1alfa-polypeptider.
AU1318797A (en) Peptides and uses thereof for therapy of celiac diseases

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment