DK10191D0 - Hidtil ukendte peptider - Google Patents

Hidtil ukendte peptider

Info

Publication number
DK10191D0
DK10191D0 DK010191A DK10191A DK10191D0 DK 10191 D0 DK10191 D0 DK 10191D0 DK 010191 A DK010191 A DK 010191A DK 10191 A DK10191 A DK 10191A DK 10191 D0 DK10191 D0 DK 10191D0
Authority
DK
Denmark
Prior art keywords
molecule
insulin
human insulin
unknown peptides
insulin analogues
Prior art date
Application number
DK010191A
Other languages
English (en)
Inventor
Jens Joergen Veilgaard Brange
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK010191A priority Critical patent/DK10191D0/da
Publication of DK10191D0 publication Critical patent/DK10191D0/da
Priority to CA002100565A priority patent/CA2100565A1/en
Priority to AU11902/92A priority patent/AU1190292A/en
Priority to JP4503787A priority patent/JPH06506444A/ja
Priority to PCT/DK1992/000019 priority patent/WO1992012999A1/en
Priority to AT92903864T priority patent/ATE136907T1/de
Priority to EP92903864A priority patent/EP0568594B1/en
Priority to DE69210011T priority patent/DE69210011T2/de
Priority to US08/301,838 priority patent/US5597796A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK010191A 1991-01-22 1991-01-22 Hidtil ukendte peptider DK10191D0 (da)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider
CA002100565A CA2100565A1 (en) 1991-01-22 1992-01-22 Insulin analogs
AU11902/92A AU1190292A (en) 1991-01-22 1992-01-22 Novel insulin analogs
JP4503787A JPH06506444A (ja) 1991-01-22 1992-01-22 新規インスリン類似体
PCT/DK1992/000019 WO1992012999A1 (en) 1991-01-22 1992-01-22 Novel insulin analogs
AT92903864T ATE136907T1 (de) 1991-01-22 1992-01-22 Neue insulinanaloge geeignet für die transdermale anwendung
EP92903864A EP0568594B1 (en) 1991-01-22 1992-01-22 NOVEL INSULIN ANALOGS suited for transdermal application
DE69210011T DE69210011T2 (de) 1991-01-22 1992-01-22 Neue Insulinanaloge geeignet für die transdermale Anwendung
US08/301,838 US5597796A (en) 1991-01-22 1994-09-07 Transdermal insulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider

Publications (1)

Publication Number Publication Date
DK10191D0 true DK10191D0 (da) 1991-01-22

Family

ID=8089747

Family Applications (1)

Application Number Title Priority Date Filing Date
DK010191A DK10191D0 (da) 1991-01-22 1991-01-22 Hidtil ukendte peptider

Country Status (9)

Country Link
US (1) US5597796A (da)
EP (1) EP0568594B1 (da)
JP (1) JPH06506444A (da)
AT (1) ATE136907T1 (da)
AU (1) AU1190292A (da)
CA (1) CA2100565A1 (da)
DE (1) DE69210011T2 (da)
DK (1) DK10191D0 (da)
WO (1) WO1992012999A1 (da)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
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CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5747453A (en) 1995-06-06 1998-05-05 Alza Corporation Method for increasing the electrotransport flux of polypeptides
IT1285405B1 (it) 1995-06-06 1998-06-03 Alza Corp Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto.
AU7678196A (en) * 1995-11-13 1997-06-05 Minimed, Inc. Methods and compositions for the delivery of monomeric proteins
US6333189B1 (en) 1996-06-06 2001-12-25 Alza Corporation Method of making an electrotransport device
US5857994A (en) * 1996-10-01 1999-01-12 Becton, Dickinson And Company Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
WO1999024015A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Buffered drug formulations for transdermal electrotransport delivery
US6562942B1 (en) * 1999-02-23 2003-05-13 Neurocrine Biosciences, Inc. Methods for treatment of diabetes using peptide analogues of insulin
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
DE60031248T2 (de) * 1999-02-18 2007-05-24 Biovalve Technologies, Inc., North Grafton Elektroaktive pore
DE10114178A1 (de) * 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
NZ519403A (en) * 2001-06-21 2005-03-24 Pfizer Prod Inc Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
JP4033382B2 (ja) * 2002-04-08 2008-01-16 久光製薬株式会社 インスリン投与装置
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
EP1991575A1 (en) * 2006-02-21 2008-11-19 Novo Nordisk A/S Single-chain insulin analogues and pharmaceutical formulations thereof
BRPI0712041A2 (pt) * 2006-05-09 2011-12-27 Novo Nordisk As derivado de insulina
US8796205B2 (en) 2006-05-09 2014-08-05 Novo Nordisk A/S Insulin derivative
JP5550338B2 (ja) 2006-07-31 2014-07-16 ノボ・ノルデイスク・エー/エス ペグ化持続型インスリン
HUE029512T2 (en) * 2006-09-22 2017-03-28 Novo Nordisk As Protease Resistant Insulin Analogs
JP5496082B2 (ja) 2007-04-30 2014-05-21 ノボ・ノルデイスク・エー/エス タンパク質組成物を乾燥させる方法、乾燥タンパク質組成物、及び乾燥タンパク質を含有する薬学的組成物
JP2009067766A (ja) * 2007-09-12 2009-04-02 Kosumedei Seiyaku Kk 経皮吸収促製剤及びそれを用いた経皮吸収システム
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
AU2009203809B2 (en) * 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
JP5762001B2 (ja) 2008-03-14 2015-08-12 ノボ・ノルデイスク・エー/エス プロテアーゼ安定化インスリンアナログ
WO2009115469A1 (en) 2008-03-18 2009-09-24 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
TW201105346A (en) * 2009-07-06 2011-02-16 Sanofi Aventis Deutschland Heat-stable and vibration-stable insulin preparations
KR101853606B1 (ko) 2009-07-06 2018-05-03 사노피-아벤티스 도이칠란트 게엠베하 메티오닌을 함유하는 수성 인슐린 제제
DK2498802T3 (da) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Farmaceutisk præparat omfattende en glp-1-agonist, et insulin og en methionin
KR101337322B1 (ko) 2009-11-13 2013-12-06 사노피-아벤티스 도이칠란트 게엠베하 Glp-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
CA2796567C (en) 2010-03-31 2016-07-12 Wockhardt Limited Composition comprising insulin and herbal oil for transdermal or transmucosal administration
ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
JP2015507916A (ja) * 2012-01-20 2015-03-16 ケース ウェスタン リザーブ ユニバーシティCase Westernreserve University グルタミン酸安定化インスリン類似体
CA2870313A1 (en) 2012-04-11 2013-10-17 Novo Nordisk A/S Insulin formulations
AU2014232894B2 (en) * 2013-03-15 2018-02-08 Case Western Reserve University Site 2 insulin analogues
AU2014333979B2 (en) 2013-10-07 2018-02-15 Novo Nordisk A/S Novel derivative of an insulin analogue
GB201321489D0 (en) 2013-12-05 2014-01-22 Chemical & Biopharmaceutical Lab Of Patras S A Biologically active insulin derivatives
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
BR112019004314A2 (pt) 2016-09-06 2019-05-28 Chemical & Biopharmaceutical Laboratories Of Patras S A derivados pró-insulina
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
TW201917134A (zh) 2017-08-17 2019-05-01 丹麥商諾佛 儂迪克股份有限公司 新穎的醯基化胰島素類似物及其用途
EP3756679A1 (en) 2019-06-28 2020-12-30 Université de Genève Compositions for use in the treatment of insulin deficiency conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
AU641631B2 (en) * 1988-12-23 1993-09-30 Novo Nordisk A/S Human insulin analogues
PT93057B (pt) * 1989-02-09 1995-12-29 Lilly Co Eli Processo para a preparacao de analogos da insulina
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain

Also Published As

Publication number Publication date
CA2100565A1 (en) 1992-07-23
DE69210011D1 (de) 1996-05-23
WO1992012999A1 (en) 1992-08-06
DE69210011T2 (de) 1996-09-05
ATE136907T1 (de) 1996-05-15
JPH06506444A (ja) 1994-07-21
EP0568594B1 (en) 1996-04-17
AU1190292A (en) 1992-08-27
EP0568594A1 (en) 1993-11-10
US5597796A (en) 1997-01-28

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Legal Events

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AHS Application shelved for other reasons than non-payment