IT1290417B1 - Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed - Google Patents

Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed

Info

Publication number
IT1290417B1
IT1290417B1 IT96MI001687A ITMI961687A IT1290417B1 IT 1290417 B1 IT1290417 B1 IT 1290417B1 IT 96MI001687 A IT96MI001687 A IT 96MI001687A IT MI961687 A ITMI961687 A IT MI961687A IT 1290417 B1 IT1290417 B1 IT 1290417B1
Authority
IT
Italy
Prior art keywords
chelates
preparation
compounds derived
metallic ions
chelating compounds
Prior art date
Application number
IT96MI001687A
Other languages
English (en)
Inventor
Pier Lucio Anelli
Andrea Beltrami
Fulvio Uggeri
Mario Virtuani
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Priority to IT96MI001687A priority Critical patent/IT1290417B1/it
Publication of ITMI961687A0 publication Critical patent/ITMI961687A0/it
Priority to DE69703373T priority patent/DE69703373T2/de
Priority to EP97112697A priority patent/EP0822180B1/en
Priority to US08/904,646 priority patent/US6099824A/en
Publication of ITMI961687A1 publication Critical patent/ITMI961687A1/it
Application granted granted Critical
Publication of IT1290417B1 publication Critical patent/IT1290417B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT96MI001687A 1996-08-02 1996-08-02 Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed IT1290417B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT96MI001687A IT1290417B1 (it) 1996-08-02 1996-08-02 Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed
DE69703373T DE69703373T2 (de) 1996-08-02 1997-07-24 Chelierende Verbindungen, ihre Chelate mit paramagnetischen Metallen, ihre Herstellung und Verwendung
EP97112697A EP0822180B1 (en) 1996-08-02 1997-07-24 Chelating compounds, their chelates with paramagnetic metal ions, their preparation and use
US08/904,646 US6099824A (en) 1996-08-02 1997-08-01 Benzyloxy derivatives of DTPA for MRI

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001687A IT1290417B1 (it) 1996-08-02 1996-08-02 Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed

Publications (3)

Publication Number Publication Date
ITMI961687A0 ITMI961687A0 (it) 1996-08-02
ITMI961687A1 ITMI961687A1 (it) 1998-02-02
IT1290417B1 true IT1290417B1 (it) 1998-12-03

Family

ID=11374757

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI001687A IT1290417B1 (it) 1996-08-02 1996-08-02 Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed

Country Status (4)

Country Link
US (1) US6099824A (it)
EP (1) EP0822180B1 (it)
DE (1) DE69703373T2 (it)
IT (1) IT1290417B1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283650B1 (it) * 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero
IT1298614B1 (it) * 1998-03-10 2000-01-12 Bracco Spa Chelati complessi di manganese ad alta relassivita' in siero
TW201514188A (zh) * 2013-03-13 2015-04-16 Lantheus Medical Imaging Inc 製備釓磷維塞三鈉單水合物之方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57183471A (en) * 1981-04-30 1982-11-11 Takemoto Oil & Fat Co Ltd Synthetic fiber treating oil agent
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5567411A (en) * 1986-11-10 1996-10-22 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
EP0603403B2 (en) * 1992-07-03 2001-06-27 Welfide Corporation Novel chelating agent, complex compound composed of said agent and metallic atom, and diagnostic agent containing said compound
DE4302287A1 (de) * 1993-01-25 1994-07-28 Schering Ag Derivatisierte DTPA-Komplexe, diese Verbindungen enthaltende pharmazeutische Mittel, ihre Verwendung und Verfahren zu deren Herstellung
WO1995015319A1 (en) * 1993-12-03 1995-06-08 Bracco S.P.A. Paramagnetic chelates for nuclear magnetic resonance diagnosis
US5582814A (en) * 1994-04-15 1996-12-10 Metasyn, Inc. 1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
DE4428874A1 (de) * 1994-08-08 1996-02-22 Schering Ag Dimere DTPA-Derivate und deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik und Therapie sowie Verfahren zur Herstellung der Komplexe und Mittel
EP0713139B1 (en) * 1994-10-20 1998-06-03 Fuji Photo Film Co., Ltd. Novel, iron complex, process for producing the same, photographic processing composition and processing process using the same
US5672335A (en) * 1994-11-30 1997-09-30 Schering Aktiengesellschaft Use of metal complexes as liver and gallbladder X-ray diagnostic agents

Also Published As

Publication number Publication date
ITMI961687A1 (it) 1998-02-02
EP0822180B1 (en) 2000-10-25
US6099824A (en) 2000-08-08
DE69703373D1 (de) 2000-11-30
ITMI961687A0 (it) 1996-08-02
EP0822180A1 (en) 1998-02-04
DE69703373T2 (de) 2001-02-22

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