IT1299566B1 - Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina - Google Patents
Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfinaInfo
- Publication number
- IT1299566B1 IT1299566B1 IT98RM000479A ITRM980479A IT1299566B1 IT 1299566 B1 IT1299566 B1 IT 1299566B1 IT 98RM000479 A IT98RM000479 A IT 98RM000479A IT RM980479 A ITRM980479 A IT RM980479A IT 1299566 B1 IT1299566 B1 IT 1299566B1
- Authority
- IT
- Italy
- Prior art keywords
- norapropylapomorphine
- hydrochloride
- pharmaceutical compositions
- transdermal patch
- compositions including
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98RM000479A IT1299566B1 (it) | 1998-07-17 | 1998-07-17 | Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina |
| CA002337516A CA2337516A1 (en) | 1998-07-17 | 1999-07-15 | Transdermal patch and topical compositions comprising propylnorapomorphine |
| PCT/IE1999/000066 WO2000003698A1 (en) | 1998-07-17 | 1999-07-15 | Transdermal patch and topical compositions comprising propylnorapomorphine |
| US09/743,576 US6592893B1 (en) | 1998-07-17 | 1999-07-15 | Transdermal patch and topical compositions comprising propylnorapomorphine |
| CNB998086673A CN1195503C (zh) | 1998-07-17 | 1999-07-15 | 含有丙基去甲阿朴吗啡的透皮药贴和局部用组合物 |
| JP2000559833A JP2002520352A (ja) | 1998-07-17 | 1999-07-15 | プロピルノルアポモルフィンを含有する経皮性パッチならびに局所性組成物 |
| EP99929658A EP1098637A1 (en) | 1998-07-17 | 1999-07-15 | Transdermal patch and topical compositions comprising propylnorapomorphine |
| AU46434/99A AU764025B2 (en) | 1998-07-17 | 1999-07-15 | Transdermal patch and topical compositions comprising propylnorapomorphine |
| ZA200100406A ZA200100406B (en) | 1998-07-17 | 2001-01-15 | Transdermal patch and topical compositions comprising propylnorapomorphine. |
| NO20010248A NO20010248L (no) | 1998-07-17 | 2001-01-15 | Transdermalt plaster og topiske sammensetninger omfattende propylnorapomorfin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98RM000479A IT1299566B1 (it) | 1998-07-17 | 1998-07-17 | Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM980479A0 ITRM980479A0 (it) | 1998-07-17 |
| ITRM980479A1 ITRM980479A1 (it) | 2000-01-17 |
| IT1299566B1 true IT1299566B1 (it) | 2000-03-16 |
Family
ID=11406053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT98RM000479A IT1299566B1 (it) | 1998-07-17 | 1998-07-17 | Cerotto transdermico e composizioni farmaceutiche comprendenti r (-)- norapropilapomorfina cloridrato e/o s (+) - norapropilapomorfina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6592893B1 (it) |
| EP (1) | EP1098637A1 (it) |
| JP (1) | JP2002520352A (it) |
| CN (1) | CN1195503C (it) |
| AU (1) | AU764025B2 (it) |
| CA (1) | CA2337516A1 (it) |
| IT (1) | IT1299566B1 (it) |
| NO (1) | NO20010248L (it) |
| WO (1) | WO2000003698A1 (it) |
| ZA (1) | ZA200100406B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506765B2 (en) * | 2000-04-07 | 2003-01-14 | Tap Pharmaceutical Products, Inc. | Apomorphine derivatives and methods for their use |
| SE0002934D0 (sv) | 2000-08-17 | 2000-08-17 | Axon Biochemicals Bv | New aporphine esters and in their use in therapy |
| DE10110953A1 (de) * | 2001-03-07 | 2002-09-19 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Verabreichung von partiellen Dopamin-D2-Agonisten |
| BRPI0415725A (pt) * | 2003-10-23 | 2006-12-19 | Cipla Ltd | formulação aspergìvel transdérmica, método para administrar um agente farmaceuticamente ativo e método para formar uma pelìcula farmaceuticamente ativa |
| ES2385737T3 (es) * | 2004-11-10 | 2012-07-31 | Hisamitsu Pharmaceutical Co., Inc. | Fármaco para uso externo y parche adhesivo |
| JP5237112B2 (ja) * | 2006-12-01 | 2013-07-17 | 日東電工株式会社 | 経皮吸収製剤 |
| KR101408454B1 (ko) * | 2006-12-01 | 2014-06-17 | 닛토덴코 가부시키가이샤 | 도네페질 함유 접착 제제의 착색을 억제하는 방법 및 도네페질의 친척 물질의 생성량을 감소시키는 방법 |
| RU2483729C2 (ru) * | 2008-05-30 | 2013-06-10 | Нитто Денко Корпорейшн | Чрескожно абсорбируемый препарат |
| RU2481826C2 (ru) * | 2008-05-30 | 2013-05-20 | Нитто Денко Корпорейшн | Содержащий донепезил адгезивный препарат и упаковка для него |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4126616A (en) * | 1975-11-10 | 1978-11-21 | William B. Hinshaw | N-propylnorapomorphine diesters |
| US5994392A (en) * | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| FR2732896B1 (fr) * | 1995-04-11 | 1997-06-13 | Prographarm Lab | Forme pharmaceutique transdermique pour l'administration percutanee de l'apomorphine |
| US5922341A (en) * | 1997-10-28 | 1999-07-13 | Vivus, Incorporated | Local administration of pharmacologically active agents to treat premature ejaculation |
-
1998
- 1998-07-17 IT IT98RM000479A patent/IT1299566B1/it active IP Right Grant
-
1999
- 1999-07-15 CN CNB998086673A patent/CN1195503C/zh not_active Expired - Fee Related
- 1999-07-15 WO PCT/IE1999/000066 patent/WO2000003698A1/en not_active Ceased
- 1999-07-15 US US09/743,576 patent/US6592893B1/en not_active Expired - Fee Related
- 1999-07-15 AU AU46434/99A patent/AU764025B2/en not_active Ceased
- 1999-07-15 CA CA002337516A patent/CA2337516A1/en not_active Abandoned
- 1999-07-15 EP EP99929658A patent/EP1098637A1/en not_active Withdrawn
- 1999-07-15 JP JP2000559833A patent/JP2002520352A/ja active Pending
-
2001
- 2001-01-15 ZA ZA200100406A patent/ZA200100406B/xx unknown
- 2001-01-15 NO NO20010248A patent/NO20010248L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000003698A1 (en) | 2000-01-27 |
| JP2002520352A (ja) | 2002-07-09 |
| CN1309558A (zh) | 2001-08-22 |
| ITRM980479A0 (it) | 1998-07-17 |
| AU4643499A (en) | 2000-02-07 |
| AU764025B2 (en) | 2003-08-07 |
| CA2337516A1 (en) | 2000-01-27 |
| ZA200100406B (en) | 2001-10-31 |
| NO20010248D0 (no) | 2001-01-15 |
| NO20010248L (no) | 2001-01-15 |
| ITRM980479A1 (it) | 2000-01-17 |
| US6592893B1 (en) | 2003-07-15 |
| EP1098637A1 (en) | 2001-05-16 |
| CN1195503C (zh) | 2005-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |