IT1313593B1 - Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo. - Google Patents

Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo.

Info

Publication number: IT1313593B1
Authority: IT; Italy
Prior art keywords: diidro; pirazino; oxo; indol derivatives; indol
Prior art date: 1999-08-03

Application number

IT1999MI001741A

Other languages

English (en)

Inventor

Ernesto Menta

Francesco Nicotra

Nicoletta Pascalli

Silvano Spinelli

Original Assignee

Novuspharma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-03

Filing date

1999-08-03

Publication date

2002-09-09

1999-08-03 Application filed by Novuspharma Spa filed Critical Novuspharma Spa

1999-08-03 Publication of ITMI991741A0 publication Critical patent/ITMI991741A0/it

1999-08-03 Priority to IT1999MI001741A priority Critical patent/IT1313593B1/it

2000-07-31 Priority to AT00949428T priority patent/ATE243698T1/de

2000-07-31 Priority to DE60003560T priority patent/DE60003560D1/de

2000-07-31 Priority to EP20000949428 priority patent/EP1200439B1/en

2000-07-31 Priority to PCT/EP2000/007418 priority patent/WO2001009136A1/en

2000-07-31 Priority to CA002393915A priority patent/CA2393915A1/en

2000-07-31 Priority to JP2001514339A priority patent/JP2003506376A/ja

2000-07-31 Priority to AU62787/00A priority patent/AU6278700A/en

2001-02-03 Publication of ITMI991741A1 publication Critical patent/ITMI991741A1/it

2002-09-09 Application granted granted Critical

2002-09-09 Publication of IT1313593B1 publication Critical patent/IT1313593B1/it

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IT1999MI001741A 1999-08-03 1999-08-03 Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo. IT1313593B1 (it)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
IT1999MI001741A IT1313593B1 (it)	1999-08-03	1999-08-03	Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo.
PCT/EP2000/007418 WO2001009136A1 (en)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-pyrazino[1,2-a]indole derivatives
DE60003560T DE60003560D1 (de)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-pyrazino[1,2-]indolederivate
EP20000949428 EP1200439B1 (en)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-parazino(1,2-a) indole derivatives
AT00949428T ATE243698T1 (de)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-pyrazino(1,2-)indolederivate
CA002393915A CA2393915A1 (en)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-pyrazino¬1,2-a\|indole derivatives
JP2001514339A JP2003506376A (ja)	1999-08-03	2000-07-31	１，２−ジヒドロ−１−オキソ−ピラジノ［１，２−ａ］インドール誘導体
AU62787/00A AU6278700A (en)	1999-08-03	2000-07-31	1,2-dihydro-1-oxo-pyrazino[1,2-a]indole derivatives

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT1999MI001741A IT1313593B1 (it)	1999-08-03	1999-08-03	Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo.

Publications (3)

Publication Number	Publication Date
ITMI991741A0 ITMI991741A0 (it)	1999-08-03
ITMI991741A1 ITMI991741A1 (it)	2001-02-03
IT1313593B1 true IT1313593B1 (it)	2002-09-09

Family

ID=11383491

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT1999MI001741A IT1313593B1 (it)	1999-08-03	1999-08-03	Derivati di 1,2-diidro-1-oxo-pirazino 1,2-a indolo.

Country Status (8)

Country	Link
EP (1)	EP1200439B1 (it)
JP (1)	JP2003506376A (it)
AT (1)	ATE243698T1 (it)
AU (1)	AU6278700A (it)
CA (1)	CA2393915A1 (it)
DE (1)	DE60003560D1 (it)
IT (1)	IT1313593B1 (it)
WO (1)	WO2001009136A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2254886B1 (en) *	2008-03-28	2016-05-25	Nerviano Medical Sciences S.r.l.	3,4-dihydro-2h-pyrazino[1,2-a]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
SG11201405328SA (en)	2012-03-16	2014-11-27	Vitae Pharmaceuticals Inc	Liver x receptor modulators
ES2607113T3 (es) *	2012-03-16	2017-03-29	Vitae Pharmaceuticals, Inc.	Moduladores de los receptores X del hígado
DK3310784T3 (da)	2015-06-17	2020-11-09	Pfizer	Tricykliske forbindelser og deres anvendelse som phosphodiesterasehæmmere

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5530019A (en) *	1993-04-05	1996-06-25	Fujisawa Pharmaceutical Co., Ltd.	Indole derivatives useful as testosterone 5α-reductase inhibitors

1999
- 1999-08-03 IT IT1999MI001741A patent/IT1313593B1/it active
2000
- 2000-07-31 CA CA002393915A patent/CA2393915A1/en not_active Abandoned
- 2000-07-31 DE DE60003560T patent/DE60003560D1/de not_active Expired - Lifetime
- 2000-07-31 JP JP2001514339A patent/JP2003506376A/ja active Pending
- 2000-07-31 EP EP20000949428 patent/EP1200439B1/en not_active Expired - Lifetime
- 2000-07-31 WO PCT/EP2000/007418 patent/WO2001009136A1/en not_active Ceased
- 2000-07-31 AU AU62787/00A patent/AU6278700A/en not_active Abandoned
- 2000-07-31 AT AT00949428T patent/ATE243698T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
ITMI991741A0 (it)	1999-08-03
AU6278700A (en)	2001-02-19
ITMI991741A1 (it)	2001-02-03
WO2001009136A1 (en)	2001-02-08
EP1200439A1 (en)	2002-05-02
ATE243698T1 (de)	2003-07-15
JP2003506376A (ja)	2003-02-18
EP1200439B1 (en)	2003-06-25
DE60003560D1 (de)	2003-07-31
CA2393915A1 (en)	2001-02-08

Similar Documents

Publication	Publication Date	Title
AU7779900A (en)	2001-04-30	Trifluoromethyl-substituted spirocyclic ketoenols
AU2795000A (en)	2000-07-12	Epothilone derivatives and their use as antitumor agents
AU3328499A (en)	1999-10-11	Phthalazinone pde iii/iv inhibitors
ATE380031T1 (de)	2007-12-15	Pyrrolo 2,3-d pyrimidinderivate enthaltende zusammensetzungen
GEP20074227B (en)	2007-10-25	PYRROLO [2,3-d] PYRIMIDINE COMPOUNDS
BR0111561A (pt)	2003-09-09	Composto pirrolo[2,3-d] pirimidina como agentes imunossupressores
CA2341291A1 (en)	2000-03-23	Pyridine ketones useful as herbicides
PT998460E (pt)	2004-07-30	Novos derivados de tetrazole
AU1783201A (en)	2001-06-04	3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
IT1315267B1 (it)	2003-02-03	Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale
MXPA02009552A (es)	2004-05-14	Derivados de imidazopiridina alquilada.
ATE386742T1 (de)	2008-03-15	Imidazonaphthyridine
MXPA03003923A (es)	2004-05-05	Compuestos de n-([1,2,4]triazoloazinil)tiofensulfonamida como herbicidas.
ATE265455T1 (de)	2004-05-15	Tetrahydropyridoverbindungen
MXPA03003942A (es)	2004-05-24	Compuestos bis-heterociclicos con actividad antitumoral y quimiosensibilizante.
DE60008400D1 (de)	2004-03-25	Triazolopyrimidinderivate
AU1781601A (en)	2001-06-04	3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
ATE356131T1 (de)	2007-03-15	Tricyclische imidazopyridine
ATE381568T1 (de)	2008-01-15	Pyrano(2,3-c)imidazo(1,2-a)pyridin-derivate zur behandlung von gastrointestinalen erkrankungen
MXPA03003798A (es)	2004-04-20	Derivados triciclicos de indol con actividad antiangiogenica.
IT1313592B1 (it)	2002-09-09	Derivati di 1h-pirido 3,4-b indol-1-one.
ATE243698T1 (de)	2003-07-15	1,2-dihydro-1-oxo-pyrazino(1,2-)indolederivate
ES2159489A1 (es)	2001-10-01	Nuevos derivados de imidazol con actividad antiinflamatoria.
MY133140A (en)	2007-10-31	N-substituted azabicycloheptane derivatives, their preparation and use
GB9911556D0 (en)	1999-07-21	Immunosuppressant tricyclic compounds