IT1320176B1 - Dispersioni solide di principi attivi nitrati. - Google Patents
Dispersioni solide di principi attivi nitrati.Info
- Publication number
- IT1320176B1 IT1320176B1 IT2000MI002803A ITMI20002803A IT1320176B1 IT 1320176 B1 IT1320176 B1 IT 1320176B1 IT 2000MI002803 A IT2000MI002803 A IT 2000MI002803A IT MI20002803 A ITMI20002803 A IT MI20002803A IT 1320176 B1 IT1320176 B1 IT 1320176B1
- Authority
- IT
- Italy
- Prior art keywords
- nitrated
- active ingredients
- solid dispersions
- dispersions
- solid
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title 1
- 239000007962 solid dispersion Substances 0.000 title 1
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Carbon And Carbon Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI002803A IT1320176B1 (it) | 2000-12-22 | 2000-12-22 | Dispersioni solide di principi attivi nitrati. |
| AT01995695T ATE275393T1 (de) | 2000-12-22 | 2001-12-18 | Feste dispersionen mit nitrataktiven wirkstoffen |
| US10/451,016 US20040071777A1 (en) | 2000-12-22 | 2001-12-18 | Solid dispersions of nitrate active principles |
| EP01995695A EP1347744B1 (en) | 2000-12-22 | 2001-12-18 | Solid dispersions of nitrate active principles |
| JP2002552531A JP2004516303A (ja) | 2000-12-22 | 2001-12-18 | ナイトレートの有効成分の固体分散体 |
| PCT/EP2001/014967 WO2002051385A1 (en) | 2000-12-22 | 2001-12-18 | Solid dispersions of nitrate active principles |
| ES01995695T ES2228983T3 (es) | 2000-12-22 | 2001-12-18 | Dispersiuones solidas de principios activos de nitrato. |
| DE60105448T DE60105448T2 (de) | 2000-12-22 | 2001-12-18 | Feste dispersionen mit nitrataktiven wirkstoffen |
| EP04103272A EP1496064A1 (en) | 2000-12-22 | 2001-12-18 | Nitrate active principle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI002803A IT1320176B1 (it) | 2000-12-22 | 2000-12-22 | Dispersioni solide di principi attivi nitrati. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI20002803A1 ITMI20002803A1 (it) | 2002-06-22 |
| IT1320176B1 true IT1320176B1 (it) | 2003-11-26 |
Family
ID=11446305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2000MI002803A IT1320176B1 (it) | 2000-12-22 | 2000-12-22 | Dispersioni solide di principi attivi nitrati. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040071777A1 (it) |
| EP (2) | EP1496064A1 (it) |
| JP (1) | JP2004516303A (it) |
| AT (1) | ATE275393T1 (it) |
| DE (1) | DE60105448T2 (it) |
| ES (1) | ES2228983T3 (it) |
| IT (1) | IT1320176B1 (it) |
| WO (1) | WO2002051385A1 (it) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
| AP2002002582A0 (en) | 1999-12-23 | 2002-09-30 | Nitromed Inc | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
| WO2002087508A2 (en) | 2001-05-02 | 2002-11-07 | Nitromed, Inc. | Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use |
| ITMI20020148A1 (it) * | 2002-01-29 | 2003-07-29 | Nicox Sa | Nuovi corticosteroidi |
| EP1479666A4 (en) | 2002-02-28 | 2010-10-13 | Japan Tobacco Inc | ESTER CONNECTION AND THEIR MEDICAL USE |
| CA2487414A1 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| US7244753B2 (en) | 2002-07-29 | 2007-07-17 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| EP1534278A4 (en) | 2002-08-01 | 2006-09-06 | Nitromed Inc | NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD |
| WO2004105728A2 (en) * | 2003-05-27 | 2004-12-09 | Ranbaxy Laboratories Limited | Solid dispersions of cefpodoxime proxetil and processes for their preparation |
| US7790197B2 (en) | 2003-06-09 | 2010-09-07 | Warner-Lambert Company Llc | Pharmaceutical compositions of atorvastatin |
| US7655692B2 (en) | 2003-06-12 | 2010-02-02 | Pfizer Inc. | Process for forming amorphous atorvastatin |
| JP4832897B2 (ja) | 2003-08-29 | 2011-12-07 | 日本たばこ産業株式会社 | エステル誘導体及びその医薬用途 |
| EP1701702A1 (en) * | 2003-12-04 | 2006-09-20 | Pfizer Products Inc. | Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride |
| US20090131342A1 (en) * | 2004-01-22 | 2009-05-21 | Nitromed, Inc. | Nitrosated and/or nitrosylated compounds, compositions and methods of use |
| US7803838B2 (en) | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US8101774B2 (en) | 2004-10-18 | 2012-01-24 | Japan Tobacco Inc. | Ester derivatives and medicinal use thereof |
| US20060160871A1 (en) * | 2004-12-07 | 2006-07-20 | Nektar Therapeutics | Stable non-crystalline formulation comprising losartan |
| EP1830817B1 (en) * | 2004-12-30 | 2013-01-02 | Pierre Fabre Medicament | Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it |
| US9089544B2 (en) * | 2007-08-24 | 2015-07-28 | Slotervaart Participaties Bv | Composition |
| MX2010009043A (es) * | 2008-02-28 | 2010-10-25 | Bial Portela & Ca Sa | Composicion farmaceutica para farmacos poco solubles. |
| AU2009223014A1 (en) * | 2008-03-11 | 2009-09-17 | Dr. Reddy's Laboratories Ltd. | Preparation of lenalidomide |
| KR101037808B1 (ko) * | 2008-07-02 | 2011-05-30 | 한국콜마 주식회사 | 가용화된 니플루믹산을 함유하는 서방성 정제 |
| GEP201706693B (en) * | 2009-10-27 | 2017-07-10 | Lupin Ltd | Solid dispersion of rifaximin |
| JP2013521318A (ja) * | 2010-03-08 | 2013-06-10 | ラティオファルム ゲー・エム・ベー・ハー | ダビガトランエテキシラートを含有する医薬組成物 |
| PH12013500082B1 (en) | 2010-07-12 | 2019-06-28 | Salix Pharmaceuticals Ltd | Formulations of rifaximin and uses thereof |
| JP7027412B2 (ja) | 2016-09-30 | 2022-03-01 | サリックス ファーマスーティカルズ，インコーポレーテッド | リファキシミンの固体分散体の形態 |
| CN110193013B (zh) * | 2019-07-02 | 2022-02-08 | 力品药业(厦门)股份有限公司 | 一种去乙酰真菌环氧乙酯固体分散体及其制备方法 |
| JP7825575B2 (ja) | 2020-06-26 | 2026-03-06 | バウシュ ヘルス アイルランド リミテッド | 標的化放出リファキシミン組成物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1256450B (it) * | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
| US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
| US5985862A (en) * | 1996-05-02 | 1999-11-16 | G.D. Searle & Co. | Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs |
| IT1285770B1 (it) * | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
| US6706283B1 (en) * | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
| IT1311922B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| AU6917400A (en) * | 1999-08-31 | 2001-03-26 | Alcon Laboratories, Inc. | Use of 5-ht1b/1d agonists to treat otic pain |
| US20040234602A1 (en) * | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
-
2000
- 2000-12-22 IT IT2000MI002803A patent/IT1320176B1/it active
-
2001
- 2001-12-18 ES ES01995695T patent/ES2228983T3/es not_active Expired - Lifetime
- 2001-12-18 EP EP04103272A patent/EP1496064A1/en not_active Withdrawn
- 2001-12-18 US US10/451,016 patent/US20040071777A1/en not_active Abandoned
- 2001-12-18 AT AT01995695T patent/ATE275393T1/de not_active IP Right Cessation
- 2001-12-18 JP JP2002552531A patent/JP2004516303A/ja active Pending
- 2001-12-18 DE DE60105448T patent/DE60105448T2/de not_active Expired - Fee Related
- 2001-12-18 EP EP01995695A patent/EP1347744B1/en not_active Expired - Lifetime
- 2001-12-18 WO PCT/EP2001/014967 patent/WO2002051385A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE60105448D1 (de) | 2004-10-14 |
| DE60105448T2 (de) | 2005-09-22 |
| WO2002051385A1 (en) | 2002-07-04 |
| ATE275393T1 (de) | 2004-09-15 |
| US20040071777A1 (en) | 2004-04-15 |
| EP1347744A1 (en) | 2003-10-01 |
| ITMI20002803A1 (it) | 2002-06-22 |
| EP1347744B1 (en) | 2004-09-08 |
| WO2002051385A8 (en) | 2002-10-31 |
| EP1496064A1 (en) | 2005-01-12 |
| JP2004516303A (ja) | 2004-06-03 |
| ES2228983T3 (es) | 2005-04-16 |
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