IT7922089A0 - Composti aminochinolinici ad azione antipertensiva. - Google Patents

Composti aminochinolinici ad azione antipertensiva.

Info

Publication number
IT7922089A0
IT7922089A0 IT7922089A IT2208979A IT7922089A0 IT 7922089 A0 IT7922089 A0 IT 7922089A0 IT 7922089 A IT7922089 A IT 7922089A IT 2208979 A IT2208979 A IT 2208979A IT 7922089 A0 IT7922089 A0 IT 7922089A0
Authority
IT
Italy
Prior art keywords
antihypertensive action
aminoquinoline compounds
aminoquinoline
compounds
antihypertensive
Prior art date
Application number
IT7922089A
Other languages
English (en)
Other versions
IT1113369B (it
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IT7922089A0 publication Critical patent/IT7922089A0/it
Application granted granted Critical
Publication of IT1113369B publication Critical patent/IT1113369B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
IT22089/79A 1978-05-05 1979-04-23 Composti aminochinolinici ad azione antipertensiva IT1113369B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/903,200 US4159331A (en) 1978-05-05 1978-05-05 Antihypertensive 4-aminoquinolines

Publications (2)

Publication Number Publication Date
IT7922089A0 true IT7922089A0 (it) 1979-04-23
IT1113369B IT1113369B (it) 1986-01-20

Family

ID=25417100

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22089/79A IT1113369B (it) 1978-05-05 1979-04-23 Composti aminochinolinici ad azione antipertensiva

Country Status (9)

Country Link
US (1) US4159331A (it)
JP (1) JPS54145684A (it)
AU (1) AU521589B2 (it)
BE (1) BE876040A (it)
DE (1) DE2914491A1 (it)
FR (1) FR2424918A1 (it)
GB (1) GB2021568B (it)
IT (1) IT1113369B (it)
NL (1) NL7903510A (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553414B1 (fr) * 1983-10-18 1986-08-14 Choay Sa Nouveaux benzenesulfonamides n-cyclises, leur procede de preparation et leur utilisation comme substance active de compositions pharmaceutiques
US4871843A (en) * 1983-10-18 1989-10-03 Dropic-Societe Civile De Gestion De Droits De Propriete Industrielle Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions
GB8424979D0 (en) * 1984-10-03 1984-11-07 Wyeth John & Brother Ltd Benzenesulphonamide derivatives
EP0215902A1 (en) * 1985-03-13 1987-04-01 The Upjohn Company Process for 4-amino quinolines
US5149700A (en) * 1990-05-30 1992-09-22 American Home Products Corporation Substituted arylsulfonamides and benzamides
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
EP1165084A4 (en) * 1999-03-03 2002-05-15 Merck & Co Inc INHIBITORS OF PRENYL PROTEIN TRANSFERASES
WO2007070506A2 (en) * 2005-12-14 2007-06-21 Amgen Inc. Diaza heterocyclic sulfonamide derivatives and their uses
WO2007108936A2 (en) * 2006-03-15 2007-09-27 Wyeth N-substituted-azacyclylamines as histamine-3 antagonists
CA2649913A1 (en) * 2006-05-19 2007-11-29 Wyeth N-benzoyl- and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists
PE20081152A1 (es) * 2006-10-06 2008-08-10 Wyeth Corp Azaciclilaminas n-sustituidas como antagonistas de histamina-3
AR066721A1 (es) * 2007-05-24 2009-09-09 Wyeth Corp Derivados de benzo[d]imidazol-1-il, composicion farmaceutica, proceso de preparacion y uso.
CA2693138A1 (en) * 2007-07-16 2009-01-22 Wyeth Llc Aminoalkylazole derivatives as histamine-3 antagonists
TW200918062A (en) * 2007-09-12 2009-05-01 Wyeth Corp Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists
US20090069300A1 (en) * 2007-09-12 2009-03-12 Wyeth Isoquinolinyl and isoindolinyl derivatives as histamine-3 antagonists
SG11201509194SA (en) 2013-05-07 2015-12-30 Univ California Radiomitigating pharmaceutical formulations
UA117779C2 (uk) 2014-02-14 2018-09-25 Такеда Фармасьютікал Компані Лімітед Піразини як модулятори gpr6
US20210393614A1 (en) 2018-10-17 2021-12-23 Duke University Quinone reductase 2 inhibitors for use as neuroprotective agents
AU2020337892B2 (en) * 2019-08-24 2025-08-14 BCN Biosciences L.L.C. Methods of treatment using BCN057 and BCN512

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
FR2229413A1 (en) 1973-05-17 1974-12-13 Upjohn Co Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc.
US3992382A (en) * 1973-06-15 1976-11-16 The Upjohn Company Quinolylaminobenzoylpiperazine-1-oxides

Also Published As

Publication number Publication date
FR2424918A1 (fr) 1979-11-30
US4159331A (en) 1979-06-26
AU4667279A (en) 1979-11-08
JPS54145684A (en) 1979-11-14
NL7903510A (nl) 1979-11-07
DE2914491A1 (de) 1979-11-08
BE876040A (fr) 1979-11-05
FR2424918B1 (it) 1983-01-14
IT1113369B (it) 1986-01-20
AU521589B2 (en) 1982-04-22
GB2021568A (en) 1979-12-05
GB2021568B (en) 1982-08-04

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