IT7922089A0 - Composti aminochinolinici ad azione antipertensiva. - Google Patents
Composti aminochinolinici ad azione antipertensiva.Info
- Publication number
- IT7922089A0 IT7922089A0 IT7922089A IT2208979A IT7922089A0 IT 7922089 A0 IT7922089 A0 IT 7922089A0 IT 7922089 A IT7922089 A IT 7922089A IT 2208979 A IT2208979 A IT 2208979A IT 7922089 A0 IT7922089 A0 IT 7922089A0
- Authority
- IT
- Italy
- Prior art keywords
- antihypertensive action
- aminoquinoline compounds
- aminoquinoline
- compounds
- antihypertensive
- Prior art date
Links
- -1 AMINOQUINOLINE COMPOUNDS Chemical class 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/903,200 US4159331A (en) | 1978-05-05 | 1978-05-05 | Antihypertensive 4-aminoquinolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7922089A0 true IT7922089A0 (it) | 1979-04-23 |
| IT1113369B IT1113369B (it) | 1986-01-20 |
Family
ID=25417100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT22089/79A IT1113369B (it) | 1978-05-05 | 1979-04-23 | Composti aminochinolinici ad azione antipertensiva |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4159331A (it) |
| JP (1) | JPS54145684A (it) |
| AU (1) | AU521589B2 (it) |
| BE (1) | BE876040A (it) |
| DE (1) | DE2914491A1 (it) |
| FR (1) | FR2424918A1 (it) |
| GB (1) | GB2021568B (it) |
| IT (1) | IT1113369B (it) |
| NL (1) | NL7903510A (it) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4871843A (en) * | 1983-10-18 | 1989-10-03 | Dropic-Societe Civile De Gestion De Droits De Propriete Industrielle | Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions |
| FR2553414B1 (fr) * | 1983-10-18 | 1986-08-14 | Choay Sa | Nouveaux benzenesulfonamides n-cyclises, leur procede de preparation et leur utilisation comme substance active de compositions pharmaceutiques |
| GB8424979D0 (en) * | 1984-10-03 | 1984-11-07 | Wyeth John & Brother Ltd | Benzenesulphonamide derivatives |
| EP0215902A1 (en) * | 1985-03-13 | 1987-04-01 | The Upjohn Company | Process for 4-amino quinolines |
| US5149700A (en) * | 1990-05-30 | 1992-09-22 | American Home Products Corporation | Substituted arylsulfonamides and benzamides |
| JPH05255089A (ja) * | 1991-12-18 | 1993-10-05 | Sanwa Kagaku Kenkyusho Co Ltd | 抗ウイルス剤 |
| WO2000051614A1 (en) * | 1999-03-03 | 2000-09-08 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferases |
| WO2007070506A2 (en) * | 2005-12-14 | 2007-06-21 | Amgen Inc. | Diaza heterocyclic sulfonamide derivatives and their uses |
| JP2009530274A (ja) * | 2006-03-15 | 2009-08-27 | ワイス | ヒスタミン−３アンタゴニストとしてのｎ−置換−アザシクリルアミン化合物 |
| EP2027086B1 (en) * | 2006-05-19 | 2011-11-16 | Wyeth LLC | N-benzoyl-pyrrolidin-3-ylamines as histamine-3 antagonists |
| PE20081152A1 (es) * | 2006-10-06 | 2008-08-10 | Wyeth Corp | Azaciclilaminas n-sustituidas como antagonistas de histamina-3 |
| AR066721A1 (es) * | 2007-05-24 | 2009-09-09 | Wyeth Corp | Derivados de benzo[d]imidazol-1-il, composicion farmaceutica, proceso de preparacion y uso. |
| AR067549A1 (es) * | 2007-07-16 | 2009-10-14 | Wyeth Corp | Compuesto de oxazol,tiazol e imidazol, composicion farmaceutica que lo comprende , proceso para la preparacion del compuesto , uso del compuesto y metodos para la inhibicion del receptor h3 y para el tratamiento de un trastorno cognitivo relacionado con o afectado por el receptor de histamina -3 (h3 |
| AP2010005202A0 (en) * | 2007-09-12 | 2010-04-30 | Wyeth Llc | Isoquinolinyl and isoindolinyl derivatives as histamines-3 antagonists |
| TW200918062A (en) * | 2007-09-12 | 2009-05-01 | Wyeth Corp | Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists |
| CA2911902A1 (en) | 2013-05-07 | 2014-11-13 | The Regents Of The University Of California | Radiomitigating pharmaceutical formulations |
| EP3105216B1 (en) | 2014-02-14 | 2018-10-10 | Takeda Pharmaceutical Company Limited | Pyrazine modulators of gpr6 |
| CN112823006B (zh) | 2018-10-17 | 2024-09-17 | 杜克大学 | 用作神经保护剂的醌还原酶2抑制剂 |
| EP4017493A4 (en) * | 2019-08-24 | 2023-08-23 | BCN Biosciences L.L.C. | Methods of treatment using bcn057 and bcn512 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3362956A (en) * | 1965-08-19 | 1968-01-09 | Sterling Drug Inc | 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines |
| FR2229413A1 (en) | 1973-05-17 | 1974-12-13 | Upjohn Co | Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc. |
| US3992382A (en) * | 1973-06-15 | 1976-11-16 | The Upjohn Company | Quinolylaminobenzoylpiperazine-1-oxides |
-
1978
- 1978-05-05 US US05/903,200 patent/US4159331A/en not_active Expired - Lifetime
-
1979
- 1979-04-10 DE DE19792914491 patent/DE2914491A1/de not_active Withdrawn
- 1979-04-23 IT IT22089/79A patent/IT1113369B/it active
- 1979-04-26 GB GB7914584A patent/GB2021568B/en not_active Expired
- 1979-05-02 AU AU46672/79A patent/AU521589B2/en not_active Ceased
- 1979-05-02 JP JP5356779A patent/JPS54145684A/ja active Pending
- 1979-05-04 BE BE0/194992A patent/BE876040A/xx not_active IP Right Cessation
- 1979-05-04 NL NL7903510A patent/NL7903510A/xx not_active Application Discontinuation
- 1979-05-04 FR FR7911350A patent/FR2424918A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IT1113369B (it) | 1986-01-20 |
| AU4667279A (en) | 1979-11-08 |
| JPS54145684A (en) | 1979-11-14 |
| AU521589B2 (en) | 1982-04-22 |
| NL7903510A (nl) | 1979-11-07 |
| FR2424918B1 (it) | 1983-01-14 |
| GB2021568A (en) | 1979-12-05 |
| DE2914491A1 (de) | 1979-11-08 |
| FR2424918A1 (fr) | 1979-11-30 |
| BE876040A (fr) | 1979-11-05 |
| US4159331A (en) | 1979-06-26 |
| GB2021568B (en) | 1982-08-04 |
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