IT8420478A0 - Amminodisolfuri analoghi della mitomicina quali inibitori di tumori. - Google Patents

Amminodisolfuri analoghi della mitomicina quali inibitori di tumori.

Info

Publication number: IT8420478A0
Authority: IT; Italy
Prior art keywords: aminodisulphides; mitomicin; analogues; tumor inhibitors; tumor
Prior art date: 1983-04-11

Application number

IT8420478A

Other languages

English (en)

Other versions

IT1176003B (it

IT8420478A1 (it

Inventor

Dolatrai Mohanlal Vyas

Terrence William Doyle

Yulin Chiang

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-04-11

Filing date

1984-04-10

Publication date

1984-04-10

1984-04-10 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1984-04-10 Publication of IT8420478A0 publication Critical patent/IT8420478A0/it

1985-10-10 Publication of IT8420478A1 publication Critical patent/IT8420478A1/it

1987-08-12 Application granted granted Critical

1987-08-12 Publication of IT1176003B publication Critical patent/IT1176003B/it

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IT20478/84A 1983-04-11 1984-04-10 Amminodisolfurti analoghi della mitomicina quali inibitori di tumori IT1176003B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US48401683A	1983-04-11	1983-04-11
US06/581,291 US4803212A (en)	1983-04-11	1984-02-24	Amino disulfides

Publications (3)

Publication Number	Publication Date
IT8420478A0 true IT8420478A0 (it)	1984-04-10
IT8420478A1 IT8420478A1 (it)	1985-10-10
IT1176003B IT1176003B (it)	1987-08-12

Family

ID=27047825

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT20478/84A IT1176003B (it)	1983-04-11	1984-04-10	Amminodisolfurti analoghi della mitomicina quali inibitori di tumori

Country Status (23)

Country	Link
US (1)	US4803212A (it)
KR (1)	KR890001488B1 (it)
AT (1)	AT387019B (it)
AU (1)	AU577523B2 (it)
CA (1)	CA1285567C (it)
CH (1)	CH661273A5 (it)
CY (1)	CY1533A (it)
DE (1)	DE3413489A1 (it)
DK (1)	DK170071B1 (it)
ES (1)	ES531338A0 (it)
FI (1)	FI78701C (it)
FR (1)	FR2543953B1 (it)
GB (1)	GB2140799B (it)
GR (1)	GR79579B (it)
HK (1)	HK82690A (it)
IE (1)	IE57348B1 (it)
IT (1)	IT1176003B (it)
LU (1)	LU85295A1 (it)
MX (1)	MX9202850A (it)
MY (1)	MY102071A (it)
NL (1)	NL8401104A (it)
PT (1)	PT78399B (it)
SE (1)	SE461735B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4487769A (en) *	1982-06-04	1984-12-11	Bristol-Myers Company	Amidines
US4866180A (en) *	1984-02-24	1989-09-12	Bristol-Myers Company	Amino disulfide thiol exchange products
JPS60255789A (ja) *	1984-06-01	1985-12-17	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) *	1984-09-04	1989-03-02	Bristol-Myers Company	Substituted 7-oxomitosanes
US4927943A (en) *	1984-09-04	1990-05-22	Bristol-Myers Company	Substituted 7-oxomitosanes
US4888341A (en) *	1984-09-04	1989-12-19	University Patents, Inc.	6-substituted mitomycin analogs
DE3674043D1 (de) *	1985-04-10	1990-10-18	Kyowa Hakko Kogyo Kk	Pharmakologisch aktive mitomycinderivate.
JPS6354380A (ja) *	1986-08-26	1988-03-08	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
JPS63150282A (ja) *	1986-12-13	1988-06-22	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
ZA886812B (en) *	1987-11-23	1989-07-26	Bristol Myers Co	Anti-tumor prodrugs
US5075454A (en) *	1990-03-08	1991-12-24	Bristol-Myers Squibb Company	7-(diphenylmethyl)oxy-9a-methoxymitosane
US5175303A (en) *	1990-03-08	1992-12-29	Bristol-Myers Squibb Company	Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3660578A (en) *	1957-04-06	1972-05-02	Kyowa Hakko Kogyo Kk	Mitomycin c
NL129868C (it) *	1963-06-07
DE1570029A1 (de) *	1964-07-09	1970-04-09	Kyowa Hakko Kogyo Kk	Verfahren zur Herstellung von Mitosanverbindungen
NL130086C (it) *	1964-07-14	1970-06-15
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
GB2093643A (en) *	1981-02-17	1982-09-02	Standard Telephones Cables Ltd	DC-to-DC converter
NZ199617A (en) *	1981-05-15	1985-08-30	University Patents Inc	Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) *	1982-06-04	1984-12-11	Bristol-Myers Company	Amidines
EP0116208B1 (en) *	1982-12-07	1988-03-30	Kyowa Hakko Kogyo Co., Ltd.	Mitomycin analogues
US4642352A (en) *	1983-12-23	1987-02-10	Bristol-Myers Company	Acylamino mitosanes
AU581673B2 (en) *	1984-09-04	1989-03-02	Bristol-Myers Company	Substituted 7-oxomitosanes

1984
- 1984-02-24 US US06/581,291 patent/US4803212A/en not_active Expired - Fee Related
- 1984-03-21 AU AU25951/84A patent/AU577523B2/en not_active Ceased
- 1984-04-04 GR GR74313A patent/GR79579B/el unknown
- 1984-04-06 FR FR8405504A patent/FR2543953B1/fr not_active Expired
- 1984-04-06 FI FI841380A patent/FI78701C/fi not_active IP Right Cessation
- 1984-04-06 ES ES531338A patent/ES531338A0/es active Granted
- 1984-04-06 NL NL8401104A patent/NL8401104A/nl not_active Application Discontinuation
- 1984-04-09 DK DK183984A patent/DK170071B1/da not_active IP Right Cessation
- 1984-04-09 CA CA000451556A patent/CA1285567C/en not_active Expired - Fee Related
- 1984-04-10 SE SE8401999A patent/SE461735B/sv not_active IP Right Cessation
- 1984-04-10 CH CH1806/84A patent/CH661273A5/de not_active IP Right Cessation
- 1984-04-10 LU LU85295A patent/LU85295A1/fr unknown
- 1984-04-10 IE IE878/84A patent/IE57348B1/en not_active IP Right Cessation
- 1984-04-10 PT PT78399A patent/PT78399B/pt not_active IP Right Cessation
- 1984-04-10 DE DE19843413489 patent/DE3413489A1/de active Granted
- 1984-04-10 GB GB08409242A patent/GB2140799B/en not_active Expired
- 1984-04-10 IT IT20478/84A patent/IT1176003B/it active
- 1984-04-11 KR KR1019840001908A patent/KR890001488B1/ko not_active Expired
- 1984-04-11 AT AT0122384A patent/AT387019B/de not_active IP Right Cessation
1987
- 1987-09-29 MY MYPI87002183A patent/MY102071A/en unknown
1990
- 1990-10-11 HK HK826/90A patent/HK82690A/xx not_active IP Right Cessation
- 1990-11-16 CY CY1533A patent/CY1533A/en unknown
1992
- 1992-06-12 MX MX9202850A patent/MX9202850A/es unknown

Also Published As

Publication number	Publication date
SE8401999L (sv)	1984-10-12
CH661273A5 (de)	1987-07-15
FI78701C (fi)	1989-09-11
FR2543953A1 (fr)	1984-10-12
IE57348B1 (en)	1992-08-12
ES8602798A1 (es)	1985-12-01
LU85295A1 (fr)	1984-11-28
DK170071B1 (da)	1995-05-15
FI78701B (fi)	1989-05-31
KR890001488B1 (ko)	1989-05-04
AU2595184A (en)	1984-10-18
DK183984A (da)	1984-10-12
PT78399B (en)	1986-07-17
CY1533A (en)	1990-11-16
GB2140799B (en)	1987-04-08
GB8409242D0 (en)	1984-05-23
FR2543953B1 (fr)	1988-08-26
AT387019B (de)	1988-11-25
DE3413489C2 (it)	1991-07-25
AU577523B2 (en)	1988-09-29
DK183984D0 (da)	1984-04-09
DE3413489A1 (de)	1984-10-11
IT1176003B (it)	1987-08-12
NL8401104A (nl)	1984-11-01
MX9202850A (es)	1992-06-30
FI841380A7 (fi)	1984-10-12
GB2140799A (en)	1984-12-05
FI841380A0 (fi)	1984-04-06
GR79579B (it)	1984-10-30
HK82690A (en)	1990-10-19
MY102071A (en)	1992-03-31
PT78399A (en)	1984-05-01
IE840878L (en)	1984-10-11
ES531338A0 (es)	1985-12-01
ATA122384A (de)	1988-04-15
IT8420478A1 (it)	1985-10-10
CA1285567C (en)	1991-07-02
US4803212A (en)	1989-02-07
SE461735B (sv)	1990-03-19
SE8401999D0 (sv)	1984-04-10

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19950428

Publication	Publication Date	Title
IT1194387B (it)	1988-09-22	Procedimento per la produzione di idrocarburi
DK478684D0 (da)	1984-10-05	Enzyminhibitorer
DK472684A (da)	1985-04-04	Enkephalinaseinhibitorer
IT8423244A0 (it)	1984-10-19	Analoghi interfenilene di prostaglandina 7-ossa-biciclo eptano sostituiti.
IT8320905A0 (it)	1983-05-03	Analoghi di prostaglandina 7-ossabicicloeptanidrazone.
IT1176003B (it)	1987-08-12	Amminodisolfurti analoghi della mitomicina quali inibitori di tumori
FI865196A0 (fi)	1986-12-18	Halostatinsubstituerade renin-inhibitorer.
IT8523232A0 (it)	1985-12-17	Analoghi di prostaglandina tetraidrotienil sostituiti.
IT1144744B (it)	1986-10-29	Procedimento per la produzione di solfobetaine
IT8323201A0 (it)	1983-10-07	Produzione di composti azoici.
IT1209875B (it)	1989-08-30	Procedimento per la produzione di 2-metilenaldeidi
IT8420049A0 (it)	1984-03-14	Analoghi di prostaglandina 7-ossabicicloeptano sostituito.
IT8424179A0 (it)	1984-12-21	Stabilizzazione di polialchilenglicoli.
IT1195939B (it)	1988-11-03	Procedimento per la produzione di attivatore plasminogeno
IT1141030B (it)	1986-10-01	Procedimento per la produzione di urea
IT1179031B (it)	1987-09-16	Procedimento per la produzione di tirosina
IT1173654B (it)	1987-06-24	Impiego di colecalciferol-derivati
IT1170744B (it)	1987-06-03	Procedimento per la produzione di o-trimetil-sililcellulose
IT1164613B (it)	1987-04-15	Procedimento per la produzione di ditiazol-disolfuri
IT8321128A0 (it)	1983-05-17	Impiego di uncolecalciferolderivato.
IT1172053B (it)	1987-06-18	Procentimento per la produzione di acetaldeide- dimetl- acetale
IT1170745B (it)	1987-06-03	Procedimento per la produzione di o-trimetilsilicellulose
IT1141061B (it)	1986-10-01	Procedimento per la produzione di uricasi
IT1176088B (it)	1987-08-12	Procedimento per la produzione di s-carbossimetilcisteina
IT8324024A1 (it)	1985-06-05	Procedimento per la produzione di polifenilenossido