IT8547698A1 - Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali - Google Patents

Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Info

Publication number
IT8547698A1
IT8547698A1 IT1985A47698A IT4769885A IT8547698A1 IT 8547698 A1 IT8547698 A1 IT 8547698A1 IT 1985A47698 A IT1985A47698 A IT 1985A47698A IT 4769885 A IT4769885 A IT 4769885A IT 8547698 A1 IT8547698 A1 IT 8547698A1
Authority
IT
Italy
Prior art keywords
monosialoganglioside
pathologies
derivatives
therapeutic use
cerebral infarction
Prior art date
Application number
IT1985A47698A
Other languages
English (en)
Other versions
IT8547698A0 (it
IT1182209B (it
Original Assignee
F I D I A Farmaceutici Italiani Derivati Ind Affini S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F I D I A Farmaceutici Italiani Derivati Ind Affini S P A filed Critical F I D I A Farmaceutici Italiani Derivati Ind Affini S P A
Publication of IT8547698A0 publication Critical patent/IT8547698A0/it
Priority to IT47698/85A priority Critical patent/IT1182209B/it
Priority to AU42747/85A priority patent/AU584090B2/en
Priority to ZA853834A priority patent/ZA853834B/xx
Priority to GR851238A priority patent/GR851238B/el
Priority to DE19853519095 priority patent/DE3519095A1/de
Priority to EP85401042A priority patent/EP0195169A3/en
Priority to JP60135846A priority patent/JPS61189223A/ja
Priority to LU85973A priority patent/LU85973A1/fr
Priority to BE1/11281A priority patent/BE902752A/nl
Publication of IT8547698A1 publication Critical patent/IT8547698A1/it
Application granted granted Critical
Publication of IT1182209B publication Critical patent/IT1182209B/it
Priority to US07/338,516 priority patent/US4940694A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT47698/85A 1985-02-18 1985-02-18 Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali IT1182209B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT47698/85A IT1182209B (it) 1985-02-18 1985-02-18 Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali
AU42747/85A AU584090B2 (en) 1985-02-18 1985-05-21 Therapeutic use of GM1 in severe cerebral ischemic strokes pathologies
ZA853834A ZA853834B (en) 1985-02-18 1985-05-21 Therapeutic use of gm1 in severe cerebral ischemic strokes pathologies
GR851238A GR851238B (it) 1985-02-18 1985-05-21
DE19853519095 DE3519095A1 (de) 1985-02-18 1985-05-28 Verwendung von gm(pfeil abwaerts)1(pfeil abwaerts) oder eines davon abgeleiteten inneren esters zur therapie von gehirnschlaegen
EP85401042A EP0195169A3 (en) 1985-02-18 1985-05-28 Therapeutic use of the monosialoganglioside gm1 in severe cerebral ischemic strokes pathologies
JP60135846A JPS61189223A (ja) 1985-02-18 1985-06-20 脳血流量増加剤
LU85973A LU85973A1 (fr) 1985-02-18 1985-06-26 Utilisation therapeutique de gm1 dans des pathologies cerebrales severes dues a une ischemie
BE1/11281A BE902752A (nl) 1985-02-18 1985-06-27 Utilisation therapeutique de gm1 dans des pathologies cerebrales severes dues a une ischemie.
US07/338,516 US4940694A (en) 1985-02-18 1988-10-20 Therapeutic use of GM1 in severe cerebral ischemic strokes pathologies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47698/85A IT1182209B (it) 1985-02-18 1985-02-18 Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Publications (3)

Publication Number Publication Date
IT8547698A0 IT8547698A0 (it) 1985-02-18
IT8547698A1 true IT8547698A1 (it) 1986-08-18
IT1182209B IT1182209B (it) 1987-09-30

Family

ID=11261961

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47698/85A IT1182209B (it) 1985-02-18 1985-02-18 Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Country Status (10)

Country Link
US (1) US4940694A (it)
EP (1) EP0195169A3 (it)
JP (1) JPS61189223A (it)
AU (1) AU584090B2 (it)
BE (1) BE902752A (it)
DE (1) DE3519095A1 (it)
GR (1) GR851238B (it)
IT (1) IT1182209B (it)
LU (1) LU85973A1 (it)
ZA (1) ZA853834B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6168418A (ja) * 1984-09-11 1986-04-08 Kanto Ishi Pharma Co Ltd 去痰薬
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
US5190925A (en) * 1989-06-08 1993-03-02 Fidia, S.P.A. Use of gangliosides in the treatment of autonomic dysfunction in Chagas' disease
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
IT1249034B (it) * 1990-06-29 1995-02-11 Fidia Spa Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
IT1254706B (it) 1991-12-23 1995-10-09 Fidia Spa Uso terapeutico del ganglioside gm1 nel trattamento del danno al midollo spinale
US5519035A (en) * 1993-07-02 1996-05-21 Cornell Research Foundation, Inc. Treatment of stroke or in anticipation of the occurrence of brain ischemia
US6083920A (en) * 1995-12-21 2000-07-04 Ayurcore, Inc. Compositions for modulating intracellular inositol trisphosphate concentration
JP2005527467A (ja) 2001-08-29 2005-09-15 ネオーズ テクノロジーズ， インコーポレイテッド 新規な合成ガングリオシド誘導体およびその組成物
CA2518171C (en) 2003-03-06 2013-07-09 Neose Technologies, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
WO2006052841A2 (en) * 2004-11-09 2006-05-18 Neose Technologies, Inc. Glycolipids
DE102006062706B4 (de) * 2006-03-30 2012-12-06 Krohne Ag Ultraschalldurchflußmeßgerät
WO2010111530A1 (en) 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipids as treatment for disease
WO2011028797A2 (en) * 2009-09-01 2011-03-10 Lazarus Therapeutics, Inc. Treatment of glaucoma and other retinopathies with gangliosides
CN103087120B (zh) * 2013-02-26 2015-12-02 北京四环制药有限公司 单唾液酸四己糖神经节苷脂的制备方法及其应用
WO2020041012A2 (en) * 2018-08-10 2020-02-27 Migrino Raymond Q Nanoliposome compositions and methods of using the same
US20220088133A1 (en) * 2020-09-11 2022-03-24 United States Government As Represented By The Department Of Veterans Affairs Nanoliposome Compositions And Methods Of Treating Stroke

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478104B1 (fr) * 1980-03-17 1986-08-08 Merieux Inst Nouveaux derives de gangliosides, leur preparation et leur application
US4435389A (en) * 1980-07-07 1984-03-06 Kabushiki Kaisha Yakult Honsha Composition for promoting growth of bifidobacteria
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
CH658458A5 (fr) * 1981-12-17 1986-11-14 Lucchini Lab Sa Procede pour l'obtention du lacto-n-norhexaosyl ceramide.
US4631294A (en) * 1985-07-05 1986-12-23 University E.M., Inc. Treatment of cerebral ischemia with dichloroacetate
ATE162080T1 (de) * 1991-07-16 1998-01-15 Schering Ag Verfahren zur herstellung von mikronisierte wirkstoffe enthaltende halbfeste zubereitungen

Also Published As

Publication number Publication date
JPS61189223A (ja) 1986-08-22
GR851238B (it) 1985-11-25
LU85973A1 (fr) 1986-01-22
EP0195169A3 (en) 1988-08-31
AU4274785A (en) 1986-08-21
IT8547698A0 (it) 1985-02-18
AU584090B2 (en) 1989-05-18
US4940694A (en) 1990-07-10
EP0195169A2 (en) 1986-09-24
DE3519095A1 (de) 1986-08-21
IT1182209B (it) 1987-09-30
BE902752A (nl) 1985-12-30
ZA853834B (en) 1986-09-24

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