IT8720621A0 - Formulazioni di steroide in soluzione acquosa per somministrazione nasale. - Google Patents

Formulazioni di steroide in soluzione acquosa per somministrazione nasale.

Info

Publication number
IT8720621A0
IT8720621A0 IT8720621A IT2062187A IT8720621A0 IT 8720621 A0 IT8720621 A0 IT 8720621A0 IT 8720621 A IT8720621 A IT 8720621A IT 2062187 A IT2062187 A IT 2062187A IT 8720621 A0 IT8720621 A0 IT 8720621A0
Authority
IT
Italy
Prior art keywords
aqueous solution
nasal administration
steroid formulations
steroid
formulations
Prior art date
Application number
IT8720621A
Other languages
English (en)
Other versions
IT1205667B (it
Inventor
Eric Joel Benjamin
Shabbir Tyabji Anik
Ya-Yin Tracy Lin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IT8720621A0 publication Critical patent/IT8720621A0/it
Application granted granted Critical
Publication of IT1205667B publication Critical patent/IT1205667B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT20621/87A 1986-05-22 1987-05-21 Formulazioni di steroide in soluzione acquosa per somministrazione nasale IT1205667B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/866,171 US4782047A (en) 1986-05-22 1986-05-22 Aqueous steroid formulations for nasal administration

Publications (2)

Publication Number Publication Date
IT8720621A0 true IT8720621A0 (it) 1987-05-21
IT1205667B IT1205667B (it) 1989-03-31

Family

ID=25347059

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20621/87A IT1205667B (it) 1986-05-22 1987-05-21 Formulazioni di steroide in soluzione acquosa per somministrazione nasale

Country Status (19)

Country Link
US (1) US4782047A (it)
EP (1) EP0246652B1 (it)
JP (1) JP2521291B2 (it)
KR (1) KR950008308B1 (it)
AT (1) ATE65183T1 (it)
AU (1) AU609718B2 (it)
CA (1) CA1288048C (it)
DE (1) DE3771389D1 (it)
DK (1) DK175238B1 (it)
ES (1) ES2031467T3 (it)
FI (1) FI88459C (it)
GR (1) GR3002317T3 (it)
HK (1) HK39094A (it)
IE (1) IE60259B1 (it)
IL (1) IL82615A (it)
IT (1) IT1205667B (it)
NO (1) NO173365C (it)
NZ (1) NZ220394A (it)
ZA (1) ZA873663B (it)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983595A (en) * 1986-05-22 1991-01-08 Syntex (U.S.A.) Inc. Aqueous steroid formulations for nasal administration
JPH0311016A (ja) * 1989-06-09 1991-01-18 Tokyo Tanabe Co Ltd ピリド［１，２―ａ］ピリミジン誘導体の水性製剤
GB9103824D0 (en) * 1991-02-23 1991-04-10 Fisons Ag Formulation
US5338732A (en) * 1991-06-18 1994-08-16 Bristol-Myers Squibb Company Megestrol acetate formulation
CA2174324A1 (en) * 1993-10-21 1995-04-27 Katsuya Mukae Pernasal composition and pernasal preparation containing the same
US5762917A (en) * 1994-09-27 1998-06-09 Virotex Corporation Method and composition for cleansing wounds with minimal cytotoxicity for minimal scarring
US5976573A (en) * 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
US6241969B1 (en) 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
US8466134B1 (en) 1998-06-26 2013-06-18 Athena Neurosciences, Inc. Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
GB9918559D0 (en) * 1999-08-07 1999-10-06 Glaxo Wellcome Kk Novel pharmaceutical formulation
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
JP2004505730A (ja) 2000-08-15 2004-02-26 ユニバーシティ　オブ　ケンタッキー　リサーチ　ファウンデーション プログラム可能多用量鼻腔内薬物送達デバイス
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
NZ538405A (en) 2002-08-01 2007-12-21 Aesgen Inc Improved treatment of cancer with glutamine and carbohydrate
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US7404489B1 (en) 2003-03-04 2008-07-29 Qol Medical, Llc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP5238779B2 (ja) * 2003-04-25 2013-07-17 ロート製薬株式会社 点鼻剤
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
US20050153946A1 (en) * 2003-12-24 2005-07-14 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
GB0400804D0 (en) 2004-01-14 2004-02-18 Innoscience Technology Bv Pharmaceutical compositions
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
WO2007022345A2 (en) * 2005-08-17 2007-02-22 Fleming And Company, Pharmaceuticals Vitamin b12 nasal spray and method of use
KR100767976B1 (ko) 2006-08-25 2007-10-18 한국유나이티드제약 주식회사 비내 건조증에 효과적인 약제학적 조성물
EP2121025B1 (en) 2007-01-19 2016-11-02 Hananja Ehf Methods and compositions for the delivery of a therapeutic agent
US20080275030A1 (en) * 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
JP2011001317A (ja) * 2009-06-19 2011-01-06 Fumakilla Ltd 鼻用洗浄剤
CA2905587A1 (en) 2013-03-15 2014-09-18 Medicis Pharmaceutical Corporation Topical compositions of flunisolide and methods of treatment
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
JP6097787B2 (ja) * 2015-06-09 2017-03-15 パル ファーマシューティカル， インコーポレーテッド 鼻内送達用シアノコバラミン低粘度水性製剤
PT3324933T (pt) 2015-07-16 2021-01-28 Marinomed Biotech Ag Método para melhorar a solubilidade aquosa de medicamentos hidrossolúveis ou ligeiramente hidrossolúveis
US11510859B2 (en) 2015-07-16 2022-11-29 Marinomed Biotech Ag Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs
JP2024526357A (ja) * 2021-07-16 2024-07-17 ドリペル ビー．ブイ． 水性ブメタニド含有液体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2989437A (en) * 1955-06-08 1961-06-20 Upjohn Co Anti-inflammatory and anti-bacterial decongestant nasal spray compositions
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4444762A (en) * 1980-04-04 1984-04-24 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
US4344940A (en) * 1981-11-30 1982-08-17 E. R. Squibb & Sons, Inc. Steroid formulation containing dipotassium EDTA
US4603131A (en) * 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose

Also Published As

Publication number Publication date
EP0246652A2 (en) 1987-11-25
FI88459C (fi) 1993-05-25
JP2521291B2 (ja) 1996-08-07
HK39094A (en) 1994-04-29
NO173365B (no) 1993-08-30
CA1288048C (en) 1991-08-27
KR870010862A (ko) 1987-12-18
DK258687A (da) 1987-11-23
EP0246652A3 (en) 1988-02-03
IE871335L (en) 1987-11-22
DK258687D0 (da) 1987-05-21
ZA873663B (en) 1988-12-28
NO872127L (no) 1987-11-23
FI872231L (fi) 1987-11-23
GR3002317T3 (en) 1992-12-30
ES2031467T3 (es) 1992-12-16
DE3771389D1 (de) 1991-08-22
IT1205667B (it) 1989-03-31
US4782047A (en) 1988-11-01
FI872231A0 (fi) 1987-05-21
NZ220394A (en) 1990-04-26
FI88459B (fi) 1993-02-15
IL82615A0 (en) 1987-11-30
ATE65183T1 (de) 1991-08-15
AU7327387A (en) 1987-11-26
KR950008308B1 (ko) 1995-07-27
AU609718B2 (en) 1991-05-09
EP0246652B1 (en) 1991-07-17
NO872127D0 (no) 1987-05-21
IL82615A (en) 1991-11-21
NO173365C (no) 1993-12-08
IE60259B1 (en) 1994-06-29
JPS62283927A (ja) 1987-12-09
DK175238B1 (da) 2004-07-19

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970530