DK258687A - Intranaslat praeparat - Google Patents

Intranaslat praeparat

Info

Publication number
DK258687A
DK258687A DK258687A DK258687A DK258687A DK 258687 A DK258687 A DK 258687A DK 258687 A DK258687 A DK 258687A DK 258687 A DK258687 A DK 258687A DK 258687 A DK258687 A DK 258687A
Authority
DK
Denmark
Prior art keywords
amount
effective amount
intranaslat
preparation
inflammatory steroid
Prior art date
Application number
DK258687A
Other languages
English (en)
Other versions
DK258687D0 (da
DK175238B1 (da
Inventor
Eric Joel Benjamin
Shabbir Tyabji Anik
Ya-Yun Tracy Lin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK258687D0 publication Critical patent/DK258687D0/da
Publication of DK258687A publication Critical patent/DK258687A/da
Application granted granted Critical
Publication of DK175238B1 publication Critical patent/DK175238B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK198702586A 1986-05-22 1987-05-21 Vandige steroidformuleringer, fremgangsmåde til fremstilling deraf samt anvendelse af sådanne steroidformuleringer til fremstilling af et medikament til behandling af den nasale mucosa DK175238B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/866,171 US4782047A (en) 1986-05-22 1986-05-22 Aqueous steroid formulations for nasal administration
US86617186 1986-05-22

Publications (3)

Publication Number Publication Date
DK258687D0 DK258687D0 (da) 1987-05-21
DK258687A true DK258687A (da) 1987-11-23
DK175238B1 DK175238B1 (da) 2004-07-19

Family

ID=25347059

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198702586A DK175238B1 (da) 1986-05-22 1987-05-21 Vandige steroidformuleringer, fremgangsmåde til fremstilling deraf samt anvendelse af sådanne steroidformuleringer til fremstilling af et medikament til behandling af den nasale mucosa

Country Status (19)

Country Link
US (1) US4782047A (da)
EP (1) EP0246652B1 (da)
JP (1) JP2521291B2 (da)
KR (1) KR950008308B1 (da)
AT (1) ATE65183T1 (da)
AU (1) AU609718B2 (da)
CA (1) CA1288048C (da)
DE (1) DE3771389D1 (da)
DK (1) DK175238B1 (da)
ES (1) ES2031467T3 (da)
FI (1) FI88459C (da)
GR (1) GR3002317T3 (da)
HK (1) HK39094A (da)
IE (1) IE60259B1 (da)
IL (1) IL82615A (da)
IT (1) IT1205667B (da)
NO (1) NO173365C (da)
NZ (1) NZ220394A (da)
ZA (1) ZA873663B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3150230A1 (en) 2007-01-19 2017-04-05 Hananja Ehf Methods and compositions for the delivery of a therapeutic agent

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983595A (en) * 1986-05-22 1991-01-08 Syntex (U.S.A.) Inc. Aqueous steroid formulations for nasal administration
JPH0311016A (ja) * 1989-06-09 1991-01-18 Tokyo Tanabe Co Ltd ピリド[1,2―a]ピリミジン誘導体の水性製剤
GB9103824D0 (en) * 1991-02-23 1991-04-10 Fisons Ag Formulation
US5338732A (en) * 1991-06-18 1994-08-16 Bristol-Myers Squibb Company Megestrol acetate formulation
KR100217258B1 (ko) * 1993-10-21 1999-09-01 나까도미 히로다카 경비조성물
US5762917A (en) * 1994-09-27 1998-06-09 Virotex Corporation Method and composition for cleansing wounds with minimal cytotoxicity for minimal scarring
US5976573A (en) * 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
US8466134B1 (en) 1998-06-26 2013-06-18 Athena Neurosciences, Inc. Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
US6241969B1 (en) 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
GB9918559D0 (en) * 1999-08-07 1999-10-06 Glaxo Wellcome Kk Novel pharmaceutical formulation
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
EP1315533A4 (en) * 2000-08-15 2007-06-27 Univ Kentucky Res Found PROGRAMMABLE MULTI-DOSE DEVICE FOR INTRANASAL MEDICINE ADMINISTRATION
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
ES2405287T3 (es) 2002-08-01 2013-05-30 Eisai Inc. Tratamiento mejorado del cáncer con glutamina
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US7404489B1 (en) 2003-03-04 2008-07-29 Qol Medical, Llc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
JP5238779B2 (ja) * 2003-04-25 2013-07-17 ロート製薬株式会社 点鼻剤
US20050153946A1 (en) * 2003-12-24 2005-07-14 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
GB0400804D0 (en) 2004-01-14 2004-02-18 Innoscience Technology Bv Pharmaceutical compositions
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
EP2522365B1 (en) 2004-11-24 2016-10-26 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
JP2009504767A (ja) 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンb12鼻用スプレーおよび使用方法
KR100767976B1 (ko) 2006-08-25 2007-10-18 한국유나이티드제약 주식회사 비내 건조증에 효과적인 약제학적 조성물
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
JP2011001317A (ja) * 2009-06-19 2011-01-06 Fumakilla Ltd 鼻用洗浄剤
CN105188758A (zh) * 2013-03-15 2015-12-23 梅迪奇斯医药公司 氟尼缩松的局部组合物及治疗方法
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
JP6097787B2 (ja) * 2015-06-09 2017-03-15 パル ファーマシューティカル, インコーポレーテッド 鼻内送達用シアノコバラミン低粘度水性製剤
US11510859B2 (en) 2015-07-16 2022-11-29 Marinomed Biotech Ag Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs
HUE053116T2 (hu) 2015-07-16 2021-06-28 Marinomed Biotech Ag Eljárás vízben oldhatatlan vagy vízben rosszul oldódó hatóanyagok vízoldhatóságának javítására

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2989437A (en) * 1955-06-08 1961-06-20 Upjohn Co Anti-inflammatory and anti-bacterial decongestant nasal spray compositions
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4444762A (en) * 1980-04-04 1984-04-24 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
US4344940A (en) * 1981-11-30 1982-08-17 E. R. Squibb & Sons, Inc. Steroid formulation containing dipotassium EDTA
US4603131A (en) * 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3150230A1 (en) 2007-01-19 2017-04-05 Hananja Ehf Methods and compositions for the delivery of a therapeutic agent

Also Published As

Publication number Publication date
AU609718B2 (en) 1991-05-09
FI872231A0 (fi) 1987-05-21
DK258687D0 (da) 1987-05-21
US4782047A (en) 1988-11-01
GR3002317T3 (en) 1992-12-30
NO872127L (no) 1987-11-23
EP0246652A2 (en) 1987-11-25
DK175238B1 (da) 2004-07-19
IE871335L (en) 1987-11-22
KR870010862A (ko) 1987-12-18
JP2521291B2 (ja) 1996-08-07
KR950008308B1 (ko) 1995-07-27
ZA873663B (en) 1988-12-28
IL82615A0 (en) 1987-11-30
ES2031467T3 (es) 1992-12-16
NO173365B (no) 1993-08-30
JPS62283927A (ja) 1987-12-09
NO173365C (no) 1993-12-08
ATE65183T1 (de) 1991-08-15
NZ220394A (en) 1990-04-26
IT1205667B (it) 1989-03-31
EP0246652B1 (en) 1991-07-17
EP0246652A3 (en) 1988-02-03
HK39094A (en) 1994-04-29
FI88459C (fi) 1993-05-25
DE3771389D1 (de) 1991-08-22
AU7327387A (en) 1987-11-26
FI872231L (fi) 1987-11-23
IE60259B1 (en) 1994-06-29
IL82615A (en) 1991-11-21
CA1288048C (en) 1991-08-27
IT8720621A0 (it) 1987-05-21
NO872127D0 (no) 1987-05-21
FI88459B (fi) 1993-02-15

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