IT8822743A0 - Esteri dell'acido 3 osso 1,2,4triazolo aperta parentesi quadra 4,3 a chiusa parentesi quadra pirimidina 6 carbossilico. - Google Patents

Esteri dell'acido 3 osso 1,2,4triazolo aperta parentesi quadra 4,3 a chiusa parentesi quadra pirimidina 6 carbossilico.

Info

Publication number
IT8822743A0
IT8822743A0 IT8822743A IT2274388A IT8822743A0 IT 8822743 A0 IT8822743 A0 IT 8822743A0 IT 8822743 A IT8822743 A IT 8822743A IT 2274388 A IT2274388 A IT 2274388A IT 8822743 A0 IT8822743 A0 IT 8822743A0
Authority
IT
Italy
Prior art keywords
square bracket
4triazole
pyrimidine
carboxylic
esters
Prior art date
Application number
IT8822743A
Other languages
English (en)
Other versions
IT1227878B (it
Inventor
Karnail Atwal
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8822743A0 publication Critical patent/IT8822743A0/it
Application granted granted Critical
Publication of IT1227878B publication Critical patent/IT1227878B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT8822743A 1987-11-25 1988-11-25 Esteri dell'acido 3 osso 1,2,4triazolo aperta parentesi quadra 4,3- c hiusa parentesi quadra pirimidina 6 carbossilico. IT1227878B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/125,089 US4883872A (en) 1987-11-25 1987-11-25 3-oxo-1,2,4-triazolo(4,3-A) pyrimidine-6-carboxylic acid esters

Publications (2)

Publication Number Publication Date
IT8822743A0 true IT8822743A0 (it) 1988-11-25
IT1227878B IT1227878B (it) 1991-05-14

Family

ID=22418133

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8822743A IT1227878B (it) 1987-11-25 1988-11-25 Esteri dell'acido 3 osso 1,2,4triazolo aperta parentesi quadra 4,3- c hiusa parentesi quadra pirimidina 6 carbossilico.

Country Status (7)

Country Link
US (1) US4883872A (it)
JP (1) JPH01186889A (it)
CA (1) CA1331177C (it)
DE (1) DE3839711A1 (it)
FR (1) FR2623502B1 (it)
GB (1) GB2212805B (it)
IT (1) IT1227878B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358950A (en) * 1991-07-05 1994-10-25 Laboratoires Upsa Triazolopyrimidine derivatives which are angiotensin II receptor antagonists
US6538004B2 (en) 2000-03-03 2003-03-25 Abbott Laboratories Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
GB2626588A (en) 2023-01-27 2024-07-31 Brilliant Planet Ltd Carotenoid production methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4214891A (en) * 1978-07-19 1980-07-29 E. I. Du Pont De Nemours And Company Triazolone herbicides
US4209621A (en) * 1979-04-27 1980-06-24 American Cyanamid Company (Substituted-phenyl)-1,2,4-triazolo[4,3-a]-pyrimidines and (substituted-phenyl)-1,2,4-triazolo[1,5-a]pyrimidines
JPS5995289A (ja) * 1982-11-24 1984-06-01 Teijin Ltd トリアゾロピリミジン誘導体その製造法及びそれを活性成分とする薬剤
FR2549834B1 (fr) * 1983-07-25 1985-10-18 Sanofi Sa Derives de triazolo-pyrimidine, leur procede de preparation et leur application therapeutique en tant que tonicardiaques
JPS60246387A (ja) * 1984-05-22 1985-12-06 Yoshitomi Pharmaceut Ind Ltd ジヒドロイミダゾ〔１，２−ａ〕ピリミジン誘導体
US4728652A (en) * 1985-05-20 1988-03-01 E. R. Squibb & Sons, Inc. 2-substituted thio or oxy-4-aryl or heterocyclo-5-carboxy-1,4-dihydropyrimidines, composition containing them, and method of using them to reduce blood pressure
EP0217142A3 (en) * 1985-09-30 1988-01-07 Yoshitomi Pharmaceutical Industries, Ltd. A polyazaheterocyclic compound
US4689414A (en) * 1986-02-24 1987-08-25 E. R. Squibb & Sons, Inc. 2-(substituted imino)-6-aryl-3,6-dihydro-4-substituted-1,5(2H)-pyrimidinecarboxylic acids and analogs
US4684656A (en) * 1986-03-14 1987-08-04 E. R. Squibb & Sons, Inc. 1,2,3,4-tetrahydro-6-substituted-4-aryl-3-(substituted sulfonyl)-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters and method of using them to lower blood pressure
US4746656A (en) * 1986-07-21 1988-05-24 E. R. Squibb & Sons, Inc. 1,2,4,7-tetrahydro-2-oxopyrazolo[1,5-a]pyrimidine derivatives
US4753946A (en) * 1987-04-08 1988-06-28 E. R. Squibb & Sons, Inc. Pyrimidinecarboxylic acid derivatives
US4769371A (en) * 1987-05-01 1988-09-06 E. R. Squibb & Sons, Inc. Dihydropyrimidine carboxylic acid esters

Also Published As

Publication number Publication date
US4883872A (en) 1989-11-28
FR2623502A1 (fr) 1989-05-26
JPH01186889A (ja) 1989-07-26
FR2623502B1 (fr) 1992-06-19
GB2212805A (en) 1989-08-02
CA1331177C (en) 1994-08-02
IT1227878B (it) 1991-05-14
DE3839711A1 (de) 1989-06-08
GB2212805B (en) 1991-05-22
GB8827462D0 (en) 1988-12-29

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971129