IT8848558A0 - Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento - Google Patents
Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamentoInfo
- Publication number
- IT8848558A0 IT8848558A0 IT8848558A IT4855888A IT8848558A0 IT 8848558 A0 IT8848558 A0 IT 8848558A0 IT 8848558 A IT8848558 A IT 8848558A IT 4855888 A IT4855888 A IT 4855888A IT 8848558 A0 IT8848558 A0 IT 8848558A0
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- cataracts
- carnitine
- acetyl
- pharmaceutical compositions
- Prior art date
Links
- 208000002177 Cataract Diseases 0.000 title 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8848558A IT1235153B (it) | 1988-11-15 | 1988-11-15 | Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento |
| EP89830491A EP0375628B1 (en) | 1988-11-15 | 1989-11-13 | Use of acetyl L-carnitine in the therapeutic treatment of cataract, and pharmaceutical compositions useful in such treatment |
| ES89830491T ES2062100T3 (es) | 1988-11-15 | 1989-11-13 | Empleo de acetil l-carnitina en el tratamiento terapeutico de cataratas y composiciones farmaceuticas utiles en este tratamiento. |
| AT89830491T ATE99172T1 (de) | 1988-11-15 | 1989-11-13 | Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung. |
| DE89830491T DE68911891T2 (de) | 1988-11-15 | 1989-11-13 | Verwendung von Acetyl-L-carnitin zur Behandlung von Katarakt, sowie pharmazeutische Zusammensetzungen für eine derartige Behandlung. |
| ZA898667A ZA898667B (en) | 1988-11-15 | 1989-11-14 | Use of acetyl l-carnitine in the therapeutic treatment of cataract and pharmaceutical compositions useful in such treatment |
| US07/436,203 US5037851A (en) | 1988-11-15 | 1989-11-14 | Use of acetyl l-carnitine in the therapeutic treatment of cataract, and pharmaceutical compositions useful in such treatment |
| JP1298729A JPH02180820A (ja) | 1988-11-15 | 1989-11-15 | アセチル―l―カルニチン白内障処置剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8848558A IT1235153B (it) | 1988-11-15 | 1988-11-15 | Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8848558A0 true IT8848558A0 (it) | 1988-11-15 |
| IT1235153B IT1235153B (it) | 1992-06-22 |
Family
ID=11267312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8848558A IT1235153B (it) | 1988-11-15 | 1988-11-15 | Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5037851A (it) |
| EP (1) | EP0375628B1 (it) |
| JP (1) | JPH02180820A (it) |
| AT (1) | ATE99172T1 (it) |
| DE (1) | DE68911891T2 (it) |
| ES (1) | ES2062100T3 (it) |
| IT (1) | IT1235153B (it) |
| ZA (1) | ZA898667B (it) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| IT1254314B (it) * | 1992-03-27 | 1995-09-14 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari. |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
| DK0951909T4 (da) | 1998-03-19 | 2011-01-24 | Sigma Tau Ind Farmaceuti | Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf |
| CA2338638C (en) * | 1998-07-30 | 2009-03-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of l-carnitine and its alkanoyl derivatives in the preparation of medicaments with anticancer activity |
| DK1341813T3 (da) * | 2000-12-15 | 2007-01-15 | Sigma Tau Ind Farmaceuti | Anvendelse af L-carnitin som stabiliseringsmiddel af proteiner |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| AU2006265248B2 (en) * | 2005-07-01 | 2011-12-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of L-carnitine or of alkanoyl L-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops |
| CA2611914C (en) | 2005-07-08 | 2013-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of a combination comprising l-carnitine or alkanoyl l-carnitine, lipid soluble benzoquinone and omega-3-polyunsaturated fatty acid for the preparation of a dietary supplement or medicament for the treatment of corneal diseases |
| US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
| US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
| EP2363126A1 (en) | 2010-03-04 | 2011-09-07 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation |
| EP2642991A1 (en) | 2010-11-22 | 2013-10-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutical method for the treatment of the leber optic |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| EP2783695A1 (en) | 2013-03-28 | 2014-10-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1184655B (it) * | 1985-10-14 | 1987-10-28 | Sigma Tau Ind Farmaceuti | Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock |
-
1988
- 1988-11-15 IT IT8848558A patent/IT1235153B/it active
-
1989
- 1989-11-13 ES ES89830491T patent/ES2062100T3/es not_active Expired - Lifetime
- 1989-11-13 EP EP89830491A patent/EP0375628B1/en not_active Expired - Lifetime
- 1989-11-13 AT AT89830491T patent/ATE99172T1/de not_active IP Right Cessation
- 1989-11-13 DE DE89830491T patent/DE68911891T2/de not_active Expired - Fee Related
- 1989-11-14 US US07/436,203 patent/US5037851A/en not_active Expired - Lifetime
- 1989-11-14 ZA ZA898667A patent/ZA898667B/xx unknown
- 1989-11-15 JP JP1298729A patent/JPH02180820A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US5037851A (en) | 1991-08-06 |
| DE68911891D1 (de) | 1994-02-10 |
| IT1235153B (it) | 1992-06-22 |
| ATE99172T1 (de) | 1994-01-15 |
| ES2062100T3 (es) | 1994-12-16 |
| DE68911891T2 (de) | 1994-04-21 |
| EP0375628A2 (en) | 1990-06-27 |
| EP0375628A3 (en) | 1991-08-14 |
| JPH02180820A (ja) | 1990-07-13 |
| ZA898667B (en) | 1990-10-31 |
| EP0375628B1 (en) | 1993-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19931014 |