ITMI20032019A1 - Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono - Google Patents

Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono

Info

Publication number: ITMI20032019A1
Authority: IT; Italy
Prior art keywords: microemulsions; retinoids; contain; pharmaceutical compositions; retinoid
Prior art date: 2003-10-17

Application number

IT002019A

Other languages

English (en)

Inventor

Pierangelo Bellato

Rita Cortesi

Elisabetta Esposito

Giovanni Gennari

Enea Menegatti

Original Assignee

Fidia Farmaceutici

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-17

Filing date

2003-10-17

Publication date

2005-04-18

2003-10-17 Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici

2003-10-17 Priority to IT002019A priority Critical patent/ITMI20032019A1/it

2004-10-08 Priority to PCT/EP2004/011236 priority patent/WO2005039532A1/en

2004-10-08 Priority to EP04790188A priority patent/EP1673065B1/en

2004-10-08 Priority to AT04790188T priority patent/ATE427737T1/de

2004-10-08 Priority to PL04790188T priority patent/PL1673065T3/pl

2004-10-08 Priority to DE602004020488T priority patent/DE602004020488D1/de

2004-10-08 Priority to AU2004283432A priority patent/AU2004283432B2/en

2004-10-08 Priority to ES04790188T priority patent/ES2322472T3/es

2004-10-08 Priority to US10/575,616 priority patent/US7781489B2/en

2004-10-08 Priority to JP2006534647A priority patent/JP2007508339A/ja

2004-10-08 Priority to SI200431127T priority patent/SI1673065T1/sl

2004-10-08 Priority to CA2542663A priority patent/CA2542663C/en

2005-04-18 Publication of ITMI20032019A1 publication Critical patent/ITMI20032019A1/it

Links

239000004530 micro-emulsion Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003995 emulsifying agent Substances 0.000 abstract 1
229920002674 hyaluronan Polymers 0.000 abstract 1
229960003160 hyaluronic acid Drugs 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1
150000004492 retinoid derivatives Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)

IT002019A 2003-10-17 2003-10-17 Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono ITMI20032019A1 (it)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
IT002019A ITMI20032019A1 (it)	2003-10-17	2003-10-17	Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono
PCT/EP2004/011236 WO2005039532A1 (en)	2003-10-17	2004-10-08	Microemulsions of retinoids, and pharmaceutical compositions containing them
EP04790188A EP1673065B1 (en)	2003-10-17	2004-10-08	Microemulsions of retinoids, and pharmaceutical compositions containing them
AT04790188T ATE427737T1 (de)	2003-10-17	2004-10-08	Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen
PL04790188T PL1673065T3 (pl)	2003-10-17	2004-10-08	Mikroemulsje retinoidów i zawierające je kompozycje farmaceutyczne
DE602004020488T DE602004020488D1 (de)	2003-10-17	2004-10-08	Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen
AU2004283432A AU2004283432B2 (en)	2003-10-17	2004-10-08	Microemulsions of retinoids, and pharmaceutical compositions containing them
ES04790188T ES2322472T3 (es)	2003-10-17	2004-10-08	Microemulsiones de retinoides y composiciones farmaceuticas que contienen las mismas.
US10/575,616 US7781489B2 (en)	2003-10-17	2004-10-08	Microemulsions of retinoids, and pharmaceutical compositions containing them
JP2006534647A JP2007508339A (ja)	2003-10-17	2004-10-08	レチノイドのマイクロエマルション、およびそれを含む医薬組成物
SI200431127T SI1673065T1 (sl)	2003-10-17	2004-10-08	Mikroemulzije retinoidov in farmacevtski sestavki, ki jih vsebujejo
CA2542663A CA2542663C (en)	2003-10-17	2004-10-08	Microemulsions of retinoids, and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT002019A ITMI20032019A1 (it)	2003-10-17	2003-10-17	Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono

Publications (1)

Publication Number	Publication Date
ITMI20032019A1 true ITMI20032019A1 (it)	2005-04-18

Family

ID=34509450

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT002019A ITMI20032019A1 (it)	2003-10-17	2003-10-17	Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono

Country Status (12)

Country	Link
US (1)	US7781489B2 (it)
EP (1)	EP1673065B1 (it)
JP (1)	JP2007508339A (it)
AT (1)	ATE427737T1 (it)
AU (1)	AU2004283432B2 (it)
CA (1)	CA2542663C (it)
DE (1)	DE602004020488D1 (it)
ES (1)	ES2322472T3 (it)
IT (1)	ITMI20032019A1 (it)
PL (1)	PL1673065T3 (it)
SI (1)	SI1673065T1 (it)
WO (1)	WO2005039532A1 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EA009031B1 (ru) *	2003-01-24	2007-10-26	Стифел Рисерч Оустрэйлиа Пти Лтд.	Пена на основе фосфата клиндамицина
FR2865651B1 (fr)	2004-01-29	2007-09-28	Fabre Pierre Dermo Cosmetique	Compositions topiques associant des fragments de hyaluronate de sodium et un retinoide utiles en dermatologie cosmetique et medicale
FR2894827B1 (fr) *	2005-12-21	2010-10-29	Galderma Res & Dev	Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
AU2007233155B2 (en) *	2006-03-29	2012-04-26	Scitech Development Llc	Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
EP1967180A1 (de) *	2007-03-06	2008-09-10	Almirall Hermal GmbH	Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist
CA2686558A1 (fr) *	2007-05-11	2008-12-11	Galderma Research & Development	Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
DE102008034944B4 (de) *	2008-07-26	2017-03-16	Arivine Pharma Ag	Mikroemulsion
PL2344198T3 (pl) *	2008-09-27	2021-05-31	Jina Pharmaceuticals Inc.	Preparaty farmaceutyczne na bazie lipidów do stosowania miejscowego
AU2010217190B2 (en)	2009-02-25	2012-10-25	Mayne Pharma Llc	Topical foam composition
WO2013142249A1 (en) *	2012-03-22	2013-09-26	Precision Dermatology, Inc.	Cyclodextrin-based microemulsions, and dermatological uses thereof
US10702604B2 (en)	2012-06-01	2020-07-07	Galderma Research & Development	Lipid nanocapsules comprising a retinoid, nanodispersion and composition containing the same, process for preparing the same and use thereof in dermatology
US10125400B2 (en)	2012-08-10	2018-11-13	Galmerma Research & Development	Method for the diagnosis of rosacea
CN105934239A (zh)	2013-12-04	2016-09-07	盖尔德马研究及发展公司	优选包含亲脂性活性剂的脂质微胶囊和包含它的组合物，它们的制备方法和它们在皮肤病学和化妆品中的用途
EP3302421B1 (fr)	2015-05-29	2021-07-07	Galderma Research & Development	Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
ES2785322T3 (es)	2016-10-11	2020-10-06	Ionia Azure Ag	Microemulsión de agua en aceite cosmética
EP4236915A4 (en) *	2020-11-01	2024-10-23	Idrs Labs Pvt Ltd	ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF ISOTRETINOIN

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IT1212892B (it) *	1983-10-11	1989-11-30	Della Valle Francesco	Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
JPS63500456A (ja) *	1985-08-13	1988-02-18	カリフオルニア　バイオテクノロジ−　インコ−ポレイテツド	薬剤に用いるミクロエマルジョン
US5023271A (en) *	1985-08-13	1991-06-11	California Biotechnology Inc.	Pharmaceutical microemulsions
JPS6245336A (ja) *	1985-08-21	1987-02-27	Toyo Biyuut Kk	乳化組成物
JPS6295132A (ja) *	1985-10-21	1987-05-01	Nippon Saafuakutanto Kogyo Kk	多価アルコ−ル中油型乳化組成物
US5055303A (en) *	1989-01-31	1991-10-08	Kv Pharmaceutical Company	Solid controlled release bioadherent emulsions
JPH03293024A (ja) *	1990-04-11	1991-12-24	Nikko Kemikaruzu Kk	レシチンが水相に分散して成る油中水型エマルション
US5110606A (en) *	1990-11-13	1992-05-05	Affinity Biotech, Inc.	Non-aqueous microemulsions for drug delivery
GB9214634D0 (en) *	1992-07-09	1992-08-19	Lalvani Kartar S	A cosmetic or pharmaceutical preparation
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JPH1118697A (ja) *	1997-07-09	1999-01-26	Toyo Beauty Kk	含油ゲル状組成物及び水中油型乳化組成物
TWI241915B (en) *	1998-05-11	2005-10-21	Ciba Sc Holding Ag	A method of preparing a pharmaceutical end formulation using a nanodispersion
DE19826503A1 (de) *	1998-06-13	1999-12-16	Beiersdorf Ag	Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Chitosan und Phospholipiden
JP2000204011A (ja)	1999-01-13	2000-07-25	Human Limited:Kk	殺菌・制菌・消臭・皮膚保水性向上液の製法
JP2001181180A (ja) *	1999-12-24	2001-07-03	Lion Corp	油中水型乳化組成物
JP4430770B2 (ja) *	2000-01-07	2010-03-10	花王株式会社	皮膚弾力性改善剤
EP1345589B1 (en) *	2000-11-29	2007-06-27	Lyotropic Therapeutics, Inc.	Solvent systems for pharmaceutical agents
WO2002058689A1 (en) *	2000-12-05	2002-08-01	Childrens Hospital Los Angeles	Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same
US6551605B2 (en) *	2001-04-06	2003-04-22	Haarmann & Reimer	Diesters or polyesters of naphthalene dicarboxylic acid as solubilizer/stabilizer for retinoids
US7820145B2 (en) *	2003-08-04	2010-10-26	Foamix Ltd.	Oleaginous pharmaceutical and cosmetic foam

2003
- 2003-10-17 IT IT002019A patent/ITMI20032019A1/it unknown
2004
- 2004-10-08 PL PL04790188T patent/PL1673065T3/pl unknown
- 2004-10-08 DE DE602004020488T patent/DE602004020488D1/de not_active Expired - Lifetime
- 2004-10-08 JP JP2006534647A patent/JP2007508339A/ja active Pending
- 2004-10-08 US US10/575,616 patent/US7781489B2/en not_active Expired - Fee Related
- 2004-10-08 SI SI200431127T patent/SI1673065T1/sl unknown
- 2004-10-08 WO PCT/EP2004/011236 patent/WO2005039532A1/en not_active Ceased
- 2004-10-08 CA CA2542663A patent/CA2542663C/en not_active Expired - Fee Related
- 2004-10-08 AU AU2004283432A patent/AU2004283432B2/en not_active Ceased
- 2004-10-08 ES ES04790188T patent/ES2322472T3/es not_active Expired - Lifetime
- 2004-10-08 EP EP04790188A patent/EP1673065B1/en not_active Expired - Lifetime
- 2004-10-08 AT AT04790188T patent/ATE427737T1/de active

Also Published As

Publication number	Publication date
AU2004283432B2 (en)	2010-02-11
ATE427737T1 (de)	2009-04-15
WO2005039532A1 (en)	2005-05-06
CA2542663A1 (en)	2005-05-06
DE602004020488D1 (de)	2009-05-20
SI1673065T1 (sl)	2009-08-31
US20070134276A1 (en)	2007-06-14
ES2322472T3 (es)	2009-06-22
PL1673065T3 (pl)	2009-09-30
CA2542663C (en)	2012-11-27
US7781489B2 (en)	2010-08-24
AU2004283432A1 (en)	2005-05-06
EP1673065B1 (en)	2009-04-08
JP2007508339A (ja)	2007-04-05
EP1673065A1 (en)	2006-06-28

Publication	Publication Date	Title
ITMI20032019A1 (it)	2005-04-18	Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono
EP1475101A4 (en)	2005-05-25	ANTIBODY-CONTAINING PHARMACEUTICAL SOLUTIONS
NO20060179L (no)	2006-03-09	Farmasoytiske sammensetninger omfattende aktive vitamin D forbindelser
DE602004027936D1 (de)	2010-08-12	Tocopherolmodifizierte therapeutische arzneimittelverbindung
HN2002000247A (es)	2003-11-24	Derivados de sulfonamida
PA8592301A1 (es)	2004-07-26	Nuevos derivados de fluoroglicosidos heterociclicos, medicamentos que contienen estos compuestos, y el uso de los mismos
BR0210139A (pt)	2004-06-08	Composições farmacêuticas
ATE415817T1 (de)	2008-12-15	Agrochemische formulierungen
ECSP077387A (es)	2007-05-30	Composiciones que contienen piperacilina, tazobactam y un ácido aminocarboxílico en un diluyente de lactato de sodio
CY1110906T1 (el)	2015-06-10	Φαρμακευτικη συνθεση για ρινικη χορηγηση φεντανυλης
ATE486587T1 (de)	2010-11-15	Formulierungen zur oralen verabreichung von wirkstoffen
NO20080220L (no)	2008-04-21	Formuleringer med hoy medikament belastning og doseringsformer
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DE60314722D1 (de)	2007-08-16	Zusammensetzung für die pharmazeutische oder dietätische verwendung zur bekämpfung von haarausfall
ECSP045493A (es)	2005-03-10	Nuevas composiciones farmacéuticas que contienen flibanserina polimorfo a
DK1458393T3 (da)	2008-10-13	Substituerede diketopiperaziner som oxytocinantagonister
EA200501697A1 (ru)	2006-06-30	Дозируемая форма, содержащая пантопразол в качестве активного ингредиента
NO20063393L (no)	2006-07-21	Farmasoytiske preparater
TW200504199A (en)	2005-02-01	Method of preventing lipids constituting lipid membrane from degradation and use thereof
BR0312171A (pt)	2005-04-05	Composição antiperspirante, método para reduzir perspiração e método de fabricação de uma composição antiperspirante
TW200507838A (en)	2005-03-01	Active substance combination comprising a 2,5-dihydroxybenzenesulfonic compound and a potassium ion channel modulator
BRPI0417265A (pt)	2007-03-06	composição farmacêutica compreendendo um princìpio ativo e sulfobetaìna
UA81649C2 (ru)	2008-01-25	Эфиры карбаминовой кислоты, которые имеют антихолинергическое действие
DK1250125T3 (da)	2004-03-29	Farmaceutiske præparater, som indeholder terbinafin
CY1106903T1 (el)	2012-09-26	Φαρμακευτικος συνδυασμος για τη θεραπεια της σπαστικοτητας και/ή του πονου