ITMI20041245A1 - Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina - Google Patents

Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina

Info

Publication number
ITMI20041245A1
ITMI20041245A1 IT001245A ITMI20041245A ITMI20041245A1 IT MI20041245 A1 ITMI20041245 A1 IT MI20041245A1 IT 001245 A IT001245 A IT 001245A IT MI20041245 A ITMI20041245 A IT MI20041245A IT MI20041245 A1 ITMI20041245 A1 IT MI20041245A1
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
cyclodestrine
injectable pharmaceutical
compositions including
diclofenac sodium
Prior art date
Application number
IT001245A
Other languages
English (en)
Inventor
Marco Pizzuti
Nadia Puppini
Giorgio Zoppetti
Original Assignee
Ibsa Inst Biochimique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibsa Inst Biochimique Sa filed Critical Ibsa Inst Biochimique Sa
Priority to IT001245A priority Critical patent/ITMI20041245A1/it
Publication of ITMI20041245A1 publication Critical patent/ITMI20041245A1/it
Priority to JP2005174529A priority patent/JP5113323B2/ja
Priority to CNB2005100768303A priority patent/CN100569230C/zh
Priority to KR1020050053096A priority patent/KR101202649B1/ko
Priority to EP05105474A priority patent/EP1609481B1/en
Priority to CA2510813A priority patent/CA2510813C/en
Priority to PT05105474T priority patent/PT1609481E/pt
Priority to US11/158,517 priority patent/US7423028B2/en
Priority to PL05105474T priority patent/PL1609481T3/pl
Priority to AT05105474T priority patent/ATE373489T1/de
Priority to DE602005002495T priority patent/DE602005002495T2/de
Priority to ES05105474T priority patent/ES2293482T3/es
Priority to DK05105474T priority patent/DK1609481T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT001245A 2004-06-22 2004-06-22 Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina ITMI20041245A1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT001245A ITMI20041245A1 (it) 2004-06-22 2004-06-22 Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina
JP2005174529A JP5113323B2 (ja) 2004-06-22 2005-06-15 ジクロフェナクナトリウムとβ−シクロデキストリンとを有する注入可能薬学組成物
CNB2005100768303A CN100569230C (zh) 2004-06-22 2005-06-17 含有双氯芬酸钠和β-环糊精的可注射药物组合物
KR1020050053096A KR101202649B1 (ko) 2004-06-22 2005-06-20 소듐 디클로페낙 및 β-시클로덱스트린을 포함하는 주사용약학 조성물
DK05105474T DK1609481T3 (da) 2004-06-22 2005-06-21 Injicerbar farmaceutiske kompositioner omfattende natrium diclofenac, betacyklodextrin og en polysorbat
EP05105474A EP1609481B1 (en) 2004-06-22 2005-06-21 Injectable pharmaceutical compositions comprising sodium diclofenac, beta-cyclodextrin and a polysorbate
CA2510813A CA2510813C (en) 2004-06-22 2005-06-21 Injectable pharmaceutical compositions comprising sodium diclofenac and .beta.-cyclodextrin
PT05105474T PT1609481E (pt) 2004-06-22 2005-06-21 Composições farmacêuticas injectáveis compreendendo diclofenaco de sódio de beta-ciclodextrina e um polissorbato
US11/158,517 US7423028B2 (en) 2004-06-22 2005-06-21 Injectable pharmaceutical compositions comprising sodium diclofenac and β-cyclodextrin
PL05105474T PL1609481T3 (pl) 2004-06-22 2005-06-21 Nadająca się do wstrzykiwania kompozycja farmaceutyczna zawierająca diklofenak sodowy, beta-cyklodekstrynę i polisorbat
AT05105474T ATE373489T1 (de) 2004-06-22 2005-06-21 Injizierbare formulierung mit natriumdiclofenac, beta-cyclodextrin und einem polysorbat
DE602005002495T DE602005002495T2 (de) 2004-06-22 2005-06-21 Injizierbare Formulierung mit Natriumdiclofenac, Beta-Cyclodextrin und einem Polysorbat
ES05105474T ES2293482T3 (es) 2004-06-22 2005-06-21 Composiciones farmaceuticas para inyeccion que comprenden diclofenaco sodico, betaciclodextrina y un polisorbato.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001245A ITMI20041245A1 (it) 2004-06-22 2004-06-22 Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina

Publications (1)

Publication Number Publication Date
ITMI20041245A1 true ITMI20041245A1 (it) 2004-09-22

Family

ID=35033310

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001245A ITMI20041245A1 (it) 2004-06-22 2004-06-22 Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina

Country Status (13)

Country Link
US (1) US7423028B2 (it)
EP (1) EP1609481B1 (it)
JP (1) JP5113323B2 (it)
KR (1) KR101202649B1 (it)
CN (1) CN100569230C (it)
AT (1) ATE373489T1 (it)
CA (1) CA2510813C (it)
DE (1) DE602005002495T2 (it)
DK (1) DK1609481T3 (it)
ES (1) ES2293482T3 (it)
IT (1) ITMI20041245A1 (it)
PL (1) PL1609481T3 (it)
PT (1) PT1609481E (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101123957B (zh) 2005-02-01 2010-12-08 特罗伊卡药品有限公司 双氯芬酸及其药学上可接受盐的注射剂
EP2003970A4 (en) * 2006-03-28 2012-07-11 Javelin Pharmaceuticals Inc FORMULATIONS OF LOW-DOSEED NON-STEROID INFLAMMATORY INHIBITORS AND BETA-CYCLODEXTRIN
AU2007230716B2 (en) 2006-03-28 2012-05-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
ITMI20121205A1 (it) 2012-07-11 2014-01-12 Glycores 2000 Srl Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione
US20140275261A1 (en) 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
CN103432132B (zh) * 2013-08-31 2015-01-21 西南大学 甲磺酸普立地诺双氯芬酸钠注射液及其制备方法
EP3397287B8 (en) * 2015-12-30 2025-07-23 F. Hoffmann-La Roche AG Formulations with reduced degradation of polysorbate
CN107126418B (zh) * 2016-02-25 2020-05-29 江苏思邈医药科技有限公司 供注射用双氯芬酸钠药物组合物及其制备方法
EP3216443A1 (en) 2016-03-10 2017-09-13 Athenion AG Beverage preparation capsule for delivery of a solubilisate
IT201600075246A1 (it) 2016-07-19 2018-01-19 Jointherapeutics S R L Composizioni comprendenti una matrice polisaccaridica per il rilascio controllato di principi attivi.
US11110073B2 (en) 2017-03-24 2021-09-07 Cadila Healthcare Limited Storage stable aqueous injectable solution comprising diclofenac
EP3388054A1 (en) 2017-04-12 2018-10-17 Athenion AG Dispensing cap containing a solubilisate of a pharmaceutically active agent or dietary supplement
US20220280463A1 (en) 2019-09-09 2022-09-08 Ftf Pharma Private Limited Pharmaceutical formulations comprising diclofenac
US11707443B2 (en) 2019-09-26 2023-07-25 Rk Pharma Inc. Storage stable aqueous parenteral solutions comprising diclofenac

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
US5554650A (en) * 1994-07-28 1996-09-10 Southern Research Institute Antiphlogistic, analgesic, antipyretic injection preparation
KR100966245B1 (ko) * 1997-03-12 2010-06-28 아보트 러보러터리즈 사이클로스포린 투여용 친수성 2원 시스템
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
US6495164B1 (en) * 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
US20020016359A1 (en) * 2000-06-29 2002-02-07 Hellberg Mark R. Compositions and methods of treating neurodegenerative diseases
US7008934B2 (en) * 2001-06-28 2006-03-07 Baxter International Inc. Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using cyclodextrins

Also Published As

Publication number Publication date
US20050282776A1 (en) 2005-12-22
CA2510813C (en) 2013-02-12
EP1609481A1 (en) 2005-12-28
ATE373489T1 (de) 2007-10-15
CA2510813A1 (en) 2005-12-22
US7423028B2 (en) 2008-09-09
CN1711996A (zh) 2005-12-28
DK1609481T3 (da) 2008-01-07
KR101202649B1 (ko) 2012-11-19
DE602005002495T2 (de) 2008-06-12
ES2293482T3 (es) 2008-03-16
KR20060049413A (ko) 2006-05-18
CN100569230C (zh) 2009-12-16
JP5113323B2 (ja) 2013-01-09
JP2006008684A (ja) 2006-01-12
PT1609481E (pt) 2007-12-31
PL1609481T3 (pl) 2008-02-29
EP1609481B1 (en) 2007-09-19
DE602005002495D1 (de) 2007-10-31

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