ITMI20042475A1 - Uso di derivati tiazolidinonici come agenti terapeutici - Google Patents

Uso di derivati tiazolidinonici come agenti terapeutici

Info

Publication number
ITMI20042475A1
ITMI20042475A1 IT002475A ITMI20042475A ITMI20042475A1 IT MI20042475 A1 ITMI20042475 A1 IT MI20042475A1 IT 002475 A IT002475 A IT 002475A IT MI20042475 A ITMI20042475 A IT MI20042475A IT MI20042475 A1 ITMI20042475 A1 IT MI20042475A1
Authority
IT
Italy
Prior art keywords
sub
thiazolidinonic
derivatives
therapeutic agents
1alpha
Prior art date
Application number
IT002475A
Other languages
English (en)
Original Assignee
Cell Therapeutics Europe Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics Europe Srl filed Critical Cell Therapeutics Europe Srl
Priority to IT002475A priority Critical patent/ITMI20042475A1/it
Publication of ITMI20042475A1 publication Critical patent/ITMI20042475A1/it
Priority to US11/793,874 priority patent/US20080261980A1/en
Priority to EP05820657A priority patent/EP1830848B1/en
Priority to MX2007007498A priority patent/MX2007007498A/es
Priority to JP2007547309A priority patent/JP2008525340A/ja
Priority to KR1020077014023A priority patent/KR20070100718A/ko
Priority to CNA2005800440053A priority patent/CN101083989A/zh
Priority to AU2005318432A priority patent/AU2005318432A1/en
Priority to DE602005018390T priority patent/DE602005018390D1/de
Priority to CA002592004A priority patent/CA2592004A1/en
Priority to AT05820657T priority patent/ATE451922T1/de
Priority to PCT/EP2005/013650 priority patent/WO2006066846A1/en
Priority to ZA200704914A priority patent/ZA200704914B/xx
Priority to IL184116A priority patent/IL184116A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IT002475A 2004-12-23 2004-12-23 Uso di derivati tiazolidinonici come agenti terapeutici ITMI20042475A1 (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT002475A ITMI20042475A1 (it) 2004-12-23 2004-12-23 Uso di derivati tiazolidinonici come agenti terapeutici
ZA200704914A ZA200704914B (en) 2004-12-23 2005-12-19 Use of Thiazolidinone derivatives as antiangiogenic agents
CNA2005800440053A CN101083989A (zh) 2004-12-23 2005-12-19 噻唑烷酮衍生物作为抗血管生成剂的用途
EP05820657A EP1830848B1 (en) 2004-12-23 2005-12-19 Use of thiazolidinone derivatives for the treatment of solid tumors
MX2007007498A MX2007007498A (es) 2004-12-23 2005-12-19 Uso de derivados de tiazolidinona como agentes antiangiogenicos.
JP2007547309A JP2008525340A (ja) 2004-12-23 2005-12-19 抗血管新生薬としてのチアゾリジノン誘導体の使用
KR1020077014023A KR20070100718A (ko) 2004-12-23 2005-12-19 티아졸리디논 유도체의 혈관형성 억제제로서의 용도
US11/793,874 US20080261980A1 (en) 2004-12-23 2005-12-19 Use of Thiazolidinone Derivatives as Antiangiogenic Agents
AU2005318432A AU2005318432A1 (en) 2004-12-23 2005-12-19 Use of thiazolidinone derivatives as antiangiogenic agents
DE602005018390T DE602005018390D1 (de) 2004-12-23 2005-12-19 Verwendung von thiazolidinon-derivaten zur behandlung von festen tumoren
CA002592004A CA2592004A1 (en) 2004-12-23 2005-12-19 Use of thiazolidinone derivatives as antiangiogenic agents
AT05820657T ATE451922T1 (de) 2004-12-23 2005-12-19 Verwendung von thiazolidinon-derivaten zur behandlung von festen tumoren
PCT/EP2005/013650 WO2006066846A1 (en) 2004-12-23 2005-12-19 Use of thiazolidinone derivatives as antiangiogenic agents
IL184116A IL184116A0 (en) 2004-12-23 2007-06-21 Use of thiazolidinone derivatives as antiangiogenic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002475A ITMI20042475A1 (it) 2004-12-23 2004-12-23 Uso di derivati tiazolidinonici come agenti terapeutici

Publications (1)

Publication Number Publication Date
ITMI20042475A1 true ITMI20042475A1 (it) 2005-03-23

Family

ID=36168693

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002475A ITMI20042475A1 (it) 2004-12-23 2004-12-23 Uso di derivati tiazolidinonici come agenti terapeutici

Country Status (14)

Country Link
US (1) US20080261980A1 (it)
EP (1) EP1830848B1 (it)
JP (1) JP2008525340A (it)
KR (1) KR20070100718A (it)
CN (1) CN101083989A (it)
AT (1) ATE451922T1 (it)
AU (1) AU2005318432A1 (it)
CA (1) CA2592004A1 (it)
DE (1) DE602005018390D1 (it)
IL (1) IL184116A0 (it)
IT (1) ITMI20042475A1 (it)
MX (1) MX2007007498A (it)
WO (1) WO2006066846A1 (it)
ZA (1) ZA200704914B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1916249A1 (en) * 2006-10-10 2008-04-30 LEK Pharmaceuticals D.D. 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents
FR2929851B1 (fr) * 2008-04-09 2012-11-30 Centre Nat Rech Scient Molecules inhibant une voie metabolique impliquant la proteine tyrosine kinase syk et procede d'identification de ces molecules
US8236838B2 (en) 2008-04-21 2012-08-07 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
WO2009131957A2 (en) 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
HRP20150341T1 (hr) * 2008-11-14 2015-05-08 Bayer Intellectual Property Gmbh Heterocikliäśki supstituirani spojevi arila kao inhibitori hif
US8343976B2 (en) 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
AR078770A1 (es) 2009-10-27 2011-11-30 Elara Pharmaceuticals Gmbh Derivados de dihidrobenzo oxacinas y tiazinas, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades inflamatorias e hiperproliferativas.
EP3033083A4 (en) * 2013-08-14 2017-06-14 North Carolina Central University A high-throughput assay for identifying small molecules that modulate amp-activated protein kinase (ampk)
US10723726B2 (en) * 2015-06-12 2020-07-28 Gb006, Inc. Solid forms of (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid
WO2021061665A1 (en) * 2019-09-23 2021-04-01 Gb006, Inc. Integrin agonist prodrugs
WO2024037910A1 (en) * 2022-08-17 2024-02-22 Institut National de la Santé et de la Recherche Médicale Syk inhibitors for use in the treatment of cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794532A (fr) * 1972-01-26 1973-07-25 Boehringer Sohn Ingelheim Nouvelles 3-hydroxymethyl-5-benzylidene-azolidinones et procede pour les fabriquer
WO1998053790A2 (en) * 1997-05-30 1998-12-03 Texas Biotechnology Corporation Compounds that inhibit the binding of vascular endothelial growth factor to its receptors
JPH11302280A (ja) * 1998-04-17 1999-11-02 Ono Pharmaceut Co Ltd チアゾリジン誘導体、およびその誘導体を有効成分とする医薬
US6706766B2 (en) * 1999-12-13 2004-03-16 President And Fellows Of Harvard College Small molecules used to increase cell death
US20040002526A1 (en) * 2002-04-03 2004-01-01 Cell Therapeutics, Inc. Phospholipase D inhibitors and uses thereof
US7220764B2 (en) * 2002-06-17 2007-05-22 The Pennsylvania State University Research Foundation Sphingosine kinase inhibitors
BR0203747A (pt) * 2002-09-10 2004-05-25 Conselho Nacional Cnpq Moléculas com atividade antitumoral e processo para a sua obtenção
WO2004028535A1 (en) * 2002-09-26 2004-04-08 Pintex Pharmaceuticals, Inc. Pin1-modulating compounds and methods of use thereof
AU2003291024A1 (en) * 2002-11-13 2004-06-03 Rigel Pharmaceuticals, Inc. Rhodanine derivatives and pharmaceutical compositions containing them
ATE458485T1 (de) * 2003-07-11 2010-03-15 Proteologics Inc Ubiquitin-ligase-hemmer und verwandte verfahren
EP1654380A4 (en) * 2003-08-14 2009-09-09 Insight Biopharmaceuticals Ltd METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING HEPARANASE ACTIVATION AND USES THEREOF
WO2005026127A1 (ja) * 2003-09-11 2005-03-24 Institute Of Medicinal Molecular Design. Inc. プラスミノゲンアクチベータインヒビター－１阻害剤
US20050282840A1 (en) * 2004-02-11 2005-12-22 Painceptor Pharma Corporation Methods of modulating neurotrophin-mediated activity

Also Published As

Publication number Publication date
WO2006066846A1 (en) 2006-06-29
IL184116A0 (en) 2007-10-31
KR20070100718A (ko) 2007-10-11
DE602005018390D1 (de) 2010-01-28
ATE451922T1 (de) 2010-01-15
EP1830848B1 (en) 2009-12-16
CA2592004A1 (en) 2006-06-29
JP2008525340A (ja) 2008-07-17
EP1830848A1 (en) 2007-09-12
MX2007007498A (es) 2007-10-10
ZA200704914B (en) 2008-10-29
AU2005318432A1 (en) 2006-06-29
CN101083989A (zh) 2007-12-05
US20080261980A1 (en) 2008-10-23

Similar Documents

Publication Publication Date Title
IL184116A0 (en) Use of thiazolidinone derivatives as antiangiogenic agents
ATE452129T1 (de) N-phenyl-2-pyrimidine-amine derivatives
DE60206911D1 (de) Imidazol-2-carbonsäureamid derivate als raf-kinase-inhibitoren
NO20060981L (no) Pyridazinderivater og deres anvendelse som terapeutiske midler
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
ATE361287T1 (de) Neue indol-2-on derivate
TNSN03110A1 (en) Azaindoles.
MXPA03005464A (es) Agentes antivirales.
PL369108A1 (en) 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
PT1404347E (pt) Nucleosidos 4'-substituidos para o tratamento de doencas mediadas pelo virus da hepatite c
SE0101387D0 (sv) Novel compounds
PT1263725E (pt) Novos compostos
DE602005002562D1 (de) Pyrrolylsubstituierte pyridoä2,3-düpyrimidin-7-one und derivate davon als therapeutische mittel
MX340965B (es) Combinaciones para el tratamiento de enfermedades que involucran la proliferacion celular.
TW200508207A (en) New benzimidazole derivatives
SE0402762D0 (sv) Indazole sulphonamide derivatives
NO20070837L (no) Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.
SE0302573D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0301701D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ATE402166T1 (de) Substituierte-1-phthalazinamine als vr-1- antagonisten
SE0301699D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302572D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
DE60119514D1 (de) Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentansäure
SE0403118D0 (sv) New compounds 2