NO20070837L - Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer. - Google Patents

Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.

Info

Publication number
NO20070837L
NO20070837L NO20070837A NO20070837A NO20070837L NO 20070837 L NO20070837 L NO 20070837L NO 20070837 A NO20070837 A NO 20070837A NO 20070837 A NO20070837 A NO 20070837A NO 20070837 L NO20070837 L NO 20070837L
Authority
NO
Norway
Prior art keywords
pyrido
preparation
pyrimidine derivatives
cancer
treatment
Prior art date
Application number
NO20070837A
Other languages
English (en)
Inventor
Pierre Perreaut
Bernard Bourrie
Samir Jegham
Pierre Casellas
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20070837L publication Critical patent/NO20070837L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen angår pyrido[2,3-d]pyrimidinderivater med den generelle formel (I), i form av en base, et addisjonssalt eller en farmasøytisk akseptabel syre, i form av hydrater eller solvater, men også i form av enantiomerer, diastereomerer og blandinger derav, samt deres fremstilling. Oppfinnelsen omhandler også en fremgangsmåte for fremstilling av nevnte derivater, farmasøytiske sammensetninger inneholdende en forbindelse med den generelle formel (I), og deres terapeutiske anvendelse.
NO20070837A 2004-07-15 2007-02-13 Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer. NO20070837L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0407898A FR2873118B1 (fr) 2004-07-15 2004-07-15 Derives de pyrido-pyrimidine, leur application en therapeutique
PCT/FR2005/001809 WO2006016067A2 (fr) 2004-07-15 2005-07-13 Derives de pyrido-pyrimidine, leur preparation, leur application dans le traitement du cancer

Publications (1)

Publication Number Publication Date
NO20070837L true NO20070837L (no) 2007-04-16

Family

ID=34947008

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070837A NO20070837L (no) 2004-07-15 2007-02-13 Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.

Country Status (28)

Country Link
US (2) US7544682B2 (no)
EP (1) EP1773835B1 (no)
JP (1) JP5161568B2 (no)
KR (1) KR101236676B1 (no)
CN (1) CN101124223A (no)
AR (1) AR049845A1 (no)
AU (1) AU2005271071B2 (no)
BR (1) BRPI0513287A (no)
CA (1) CA2572614A1 (no)
CR (1) CR8842A (no)
EA (1) EA011406B1 (no)
EC (1) ECSP067111A (no)
FR (1) FR2873118B1 (no)
GT (1) GT200500191A (no)
HN (1) HN2005000370A (no)
IL (1) IL180256A (no)
MA (1) MA28742B1 (no)
MX (1) MX2007000508A (no)
NO (1) NO20070837L (no)
PA (1) PA8639301A1 (no)
PE (1) PE20060380A1 (no)
SV (1) SV2006002170A (no)
TN (1) TNSN06440A1 (no)
TW (1) TWI391390B (no)
UA (1) UA95223C2 (no)
UY (1) UY29015A1 (no)
WO (1) WO2006016067A2 (no)
ZA (1) ZA200700992B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873118B1 (fr) * 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
BRPI0610133A2 (pt) * 2005-05-17 2010-06-01 Schering Corp heterociclos como agonistas de receptor de ácido nicotìnico para o tratamento de dislipidemia
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
US7750015B2 (en) * 2005-05-17 2010-07-06 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
FR2887882B1 (fr) 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
CN101400682A (zh) * 2006-01-20 2009-04-01 先灵公司 治疗异常脂血症的杂环烟酸受体激动剂
FR2910813B1 (fr) 2006-12-28 2009-02-06 Sanofi Aventis Sa Nouvelle utilisation therapeutique pour le traitement des leucemies
TW200835497A (en) * 2007-01-11 2008-09-01 Astrazeneca Ab Chemical compounds 636
SA08280783B1 (ar) * 2007-01-11 2011-04-24 استرازينيكا ايه بي مشتقات بيريدوبيريميدين كمثبطات pde4
ES2608940T3 (es) * 2007-06-15 2017-04-17 Msd K.K. Derivado de bicicloanilina
FR2933701A1 (fr) * 2008-07-08 2010-01-15 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
FR2955109B1 (fr) * 2010-01-08 2012-09-07 Sanofi Aventis Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique

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GB1171218A (en) 1967-11-09 1969-11-19 Parke Davis & Co New Heterocyclic Amine Compounds and Methods for their Production
HUT76853A (en) * 1994-11-14 1997-12-29 Warner Lambert Co 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation and pharmaceutical compositions containing the same
IL115256A0 (en) * 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
EP1218336A2 (en) 1999-09-20 2002-07-03 Takeda Chemical Industries, Ltd. Melanin concentrating hormone antagonist
US7053070B2 (en) * 2000-01-25 2006-05-30 Warner-Lambert Company Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors
CZ20022475A3 (cs) 2000-01-25 2003-03-12 Warner-Lambert Company Pyrido[2,3-d]pyrimidin-2,7-diaminové inhibitory kinázy
PL358271A1 (pl) 2000-03-06 2004-08-09 Warner-Lambert Company 5-alkilopirydo[2,3-D]pirymidyny jako inhibitory kinazy tyrozyny
CA2417942C (en) 2000-08-04 2010-06-29 Warner-Lambert Company 2-(4-pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
WO2003000011A2 (en) 2001-06-21 2003-01-03 Ariad Pharmaceuticals, Inc. Novel pyridopyrimidines and uses thereof
WO2003026664A1 (en) * 2001-09-26 2003-04-03 Bayer Corporation 2-phenylamino-4- (5-pyrazolylamino) -pyramidine derivatives as kinase inhibitors, in particular, src kinase inhibitors
AU2002361846A1 (en) * 2001-12-21 2003-07-15 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
EP1492790A1 (en) * 2002-04-03 2005-01-05 F. Hoffmann-La Roche Ag Imidazo fused compounds
AU2002952453A0 (en) * 2002-11-01 2002-11-21 Novogen Research Pty Ltd Aminated isoflavonoid derivatives and uses thereof
TW200413381A (en) * 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
WO2004063195A1 (en) 2003-01-03 2004-07-29 Sloan-Kettering Institute For Cancer Research Pyridopyrimidine kinase inhibitors
TW200502236A (en) * 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
AU2004279427B2 (en) * 2003-10-08 2008-07-03 Irm Llc Compounds and compositions as protein kinase inhibitors
WO2005105097A2 (en) 2004-04-28 2005-11-10 Gpc Biotech Ag Pyridopyrimidines for treating inflammatory and other diseases
FR2873118B1 (fr) * 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.

Also Published As

Publication number Publication date
IL180256A0 (en) 2007-07-04
UY29015A1 (es) 2006-02-24
EP1773835A2 (fr) 2007-04-18
TWI391390B (zh) 2013-04-01
US20090233923A1 (en) 2009-09-17
PA8639301A1 (es) 2006-11-09
EA200700144A1 (ru) 2007-08-31
FR2873118B1 (fr) 2007-11-23
CN101124223A (zh) 2008-02-13
HN2005000370A (es) 2009-06-01
SV2006002170A (es) 2006-01-13
JP5161568B2 (ja) 2013-03-13
AR049845A1 (es) 2006-09-06
CA2572614A1 (fr) 2006-02-16
KR101236676B1 (ko) 2013-02-22
ECSP067111A (es) 2007-01-26
BRPI0513287A (pt) 2008-05-06
UA95223C2 (ru) 2011-07-25
US7893259B2 (en) 2011-02-22
MX2007000508A (es) 2007-03-29
EA011406B1 (ru) 2009-02-27
IL180256A (en) 2014-04-30
TNSN06440A1 (fr) 2008-02-22
FR2873118A1 (fr) 2006-01-20
AU2005271071A1 (en) 2006-02-16
JP2008506673A (ja) 2008-03-06
WO2006016067A2 (fr) 2006-02-16
KR20070037489A (ko) 2007-04-04
WO2006016067A3 (fr) 2006-06-01
MA28742B1 (fr) 2007-07-02
PE20060380A1 (es) 2006-06-06
TW200607808A (en) 2006-03-01
CR8842A (es) 2007-08-28
US20070167469A1 (en) 2007-07-19
EP1773835B1 (fr) 2014-09-24
ZA200700992B (en) 2008-05-28
US7544682B2 (en) 2009-06-09
GT200500191A (es) 2006-03-07
AU2005271071B2 (en) 2011-09-15

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