NO20070837L - Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer. - Google Patents

Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.

Info

Publication number
NO20070837L
NO20070837L NO20070837A NO20070837A NO20070837L NO 20070837 L NO20070837 L NO 20070837L NO 20070837 A NO20070837 A NO 20070837A NO 20070837 A NO20070837 A NO 20070837A NO 20070837 L NO20070837 L NO 20070837L
Authority
NO
Norway
Prior art keywords
pyrido
preparation
pyrimidine derivatives
cancer
treatment
Prior art date
Application number
NO20070837A
Other languages
English (en)
Inventor
Pierre Perreaut
Bernard Bourrie
Samir Jegham
Pierre Casellas
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20070837L publication Critical patent/NO20070837L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen angår pyrido[2,3-d]pyrimidinderivater med den generelle formel (I), i form av en base, et addisjonssalt eller en farmasøytisk akseptabel syre, i form av hydrater eller solvater, men også i form av enantiomerer, diastereomerer og blandinger derav, samt deres fremstilling. Oppfinnelsen omhandler også en fremgangsmåte for fremstilling av nevnte derivater, farmasøytiske sammensetninger inneholdende en forbindelse med den generelle formel (I), og deres terapeutiske anvendelse.
NO20070837A 2004-07-15 2007-02-13 Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer. NO20070837L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0407898A FR2873118B1 (fr) 2004-07-15 2004-07-15 Derives de pyrido-pyrimidine, leur application en therapeutique
PCT/FR2005/001809 WO2006016067A2 (fr) 2004-07-15 2005-07-13 Derives de pyrido-pyrimidine, leur preparation, leur application dans le traitement du cancer

Publications (1)

Publication Number Publication Date
NO20070837L true NO20070837L (no) 2007-04-16

Family

ID=34947008

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070837A NO20070837L (no) 2004-07-15 2007-02-13 Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.

Country Status (28)

Country Link
US (2) US7544682B2 (no)
EP (1) EP1773835B1 (no)
JP (1) JP5161568B2 (no)
KR (1) KR101236676B1 (no)
CN (1) CN101124223A (no)
AR (1) AR049845A1 (no)
AU (1) AU2005271071B2 (no)
BR (1) BRPI0513287A (no)
CA (1) CA2572614A1 (no)
CR (1) CR8842A (no)
EA (1) EA011406B1 (no)
EC (1) ECSP067111A (no)
FR (1) FR2873118B1 (no)
GT (1) GT200500191A (no)
HN (1) HN2005000370A (no)
IL (1) IL180256A (no)
MA (1) MA28742B1 (no)
MX (1) MX2007000508A (no)
NO (1) NO20070837L (no)
PA (1) PA8639301A1 (no)
PE (1) PE20060380A1 (no)
SV (1) SV2006002170A (no)
TN (1) TNSN06440A1 (no)
TW (1) TWI391390B (no)
UA (1) UA95223C2 (no)
UY (1) UY29015A1 (no)
WO (1) WO2006016067A2 (no)
ZA (1) ZA200700992B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873118B1 (fr) * 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
US7750015B2 (en) * 2005-05-17 2010-07-06 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
US7723342B2 (en) * 2005-05-17 2010-05-25 Schering Corporation Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
FR2887882B1 (fr) 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
KR20080091814A (ko) * 2006-01-20 2008-10-14 쉐링 코포레이션 지질혈증장애의 치료를 위한 니코틴산 수용체 효능제로서의헤테로사이클
FR2910813B1 (fr) * 2006-12-28 2009-02-06 Sanofi Aventis Sa Nouvelle utilisation therapeutique pour le traitement des leucemies
SA08280783B1 (ar) * 2007-01-11 2011-04-24 استرازينيكا ايه بي مشتقات بيريدوبيريميدين كمثبطات pde4
TW200835497A (en) * 2007-01-11 2008-09-01 Astrazeneca Ab Chemical compounds 636
CA2689429C (en) * 2007-06-15 2012-08-21 Banyu Pharmaceutical Co., Ltd. Bicycloaniline derivatives
FR2933701A1 (fr) * 2008-07-08 2010-01-15 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
FR2955109B1 (fr) * 2010-01-08 2012-09-07 Sanofi Aventis Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique

Family Cites Families (23)

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GB1171218A (en) * 1967-11-09 1969-11-19 Parke Davis & Co New Heterocyclic Amine Compounds and Methods for their Production
IL115256A0 (en) * 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
MX9702245A (es) * 1994-11-14 1997-06-28 Warner Lambert Co Seis-aril-pirido(2,3-d)pirimidinas y naftiridinas para inhibir la proliferacion celular mediada por la proteina cinasa tirosina.
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
US7115750B1 (en) 1999-09-20 2006-10-03 Takeda Pharmaceutical Company Limited Melanin concentrating hormone antagonist
US7053070B2 (en) * 2000-01-25 2006-05-30 Warner-Lambert Company Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors
WO2001055147A1 (en) 2000-01-25 2001-08-02 Warner-Lambert Company PYRIDO[2,3-d]PYRIMIDINE-2,7-DIAMINE KINASE INHIBITORS
EE200200506A (et) 2000-03-06 2004-02-16 Warner-Lambert Company 5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid
JP2004519422A (ja) 2000-08-04 2004-07-02 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー ２−（４−ピリジル）アミノ−６−ジアルコキシフェニルピリド〔２，３−ｄ〕ピリミジン−７−オン
AU2002324450A1 (en) 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel pyridopyrimidines and uses thereof
WO2003026664A1 (en) * 2001-09-26 2003-04-03 Bayer Corporation 2-phenylamino-4- (5-pyrazolylamino) -pyramidine derivatives as kinase inhibitors, in particular, src kinase inhibitors
WO2003055866A1 (en) * 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
PL374544A1 (en) * 2002-04-03 2005-10-31 F.Hoffmann-La Roche Ag Imidazo fused compounds
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TW200413381A (en) * 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
WO2004063195A1 (en) 2003-01-03 2004-07-29 Sloan-Kettering Institute For Cancer Research Pyridopyrimidine kinase inhibitors
TW200502236A (en) * 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
JP4758349B2 (ja) * 2003-10-08 2011-08-24 アイアールエム・リミテッド・ライアビリティ・カンパニー タンパク質キナーゼ阻害剤としての化合物および組成物
WO2005105097A2 (en) 2004-04-28 2005-11-10 Gpc Biotech Ag Pyridopyrimidines for treating inflammatory and other diseases
FR2873118B1 (fr) * 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.

Also Published As

Publication number Publication date
US7893259B2 (en) 2011-02-22
HN2005000370A (es) 2009-06-01
GT200500191A (es) 2006-03-07
PA8639301A1 (es) 2006-11-09
FR2873118A1 (fr) 2006-01-20
FR2873118B1 (fr) 2007-11-23
ZA200700992B (en) 2008-05-28
TNSN06440A1 (fr) 2008-02-22
AU2005271071A1 (en) 2006-02-16
US20090233923A1 (en) 2009-09-17
IL180256A0 (en) 2007-07-04
WO2006016067A3 (fr) 2006-06-01
EA200700144A1 (ru) 2007-08-31
JP2008506673A (ja) 2008-03-06
IL180256A (en) 2014-04-30
US20070167469A1 (en) 2007-07-19
CR8842A (es) 2007-08-28
CN101124223A (zh) 2008-02-13
MX2007000508A (es) 2007-03-29
JP5161568B2 (ja) 2013-03-13
EP1773835B1 (fr) 2014-09-24
AU2005271071B2 (en) 2011-09-15
US7544682B2 (en) 2009-06-09
UY29015A1 (es) 2006-02-24
MA28742B1 (fr) 2007-07-02
TWI391390B (zh) 2013-04-01
SV2006002170A (es) 2006-01-13
ECSP067111A (es) 2007-01-26
EA011406B1 (ru) 2009-02-27
WO2006016067A2 (fr) 2006-02-16
CA2572614A1 (fr) 2006-02-16
KR101236676B1 (ko) 2013-02-22
PE20060380A1 (es) 2006-06-06
UA95223C2 (ru) 2011-07-25
BRPI0513287A (pt) 2008-05-06
TW200607808A (en) 2006-03-01
AR049845A1 (es) 2006-09-06
EP1773835A2 (fr) 2007-04-18
KR20070037489A (ko) 2007-04-04

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Legal Events

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