ITMI20121109A1 - Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici - Google Patents

Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici Download PDF

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Publication number
ITMI20121109A1
ITMI20121109A1 IT001109A ITMI20121109A ITMI20121109A1 IT MI20121109 A1 ITMI20121109 A1 IT MI20121109A1 IT 001109 A IT001109 A IT 001109A IT MI20121109 A ITMI20121109 A IT MI20121109A IT MI20121109 A1 ITMI20121109 A1 IT MI20121109A1
Authority
IT
Italy
Prior art keywords
acid
derivatives
composition
gas
alternatively
Prior art date
Application number
IT001109A
Other languages
English (en)
Italian (it)
Inventor
Luigi Amelotti
Lorenzo Secondini
Original Assignee
Rode Pharma S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rode Pharma S R L filed Critical Rode Pharma S R L
Priority to IT001109A priority Critical patent/ITMI20121109A1/it
Priority to EP13744788.4A priority patent/EP2863904B1/en
Priority to CN201380042898.2A priority patent/CN104540503A/zh
Priority to PCT/IB2013/001360 priority patent/WO2014001882A1/en
Priority to US14/408,553 priority patent/US9775348B2/en
Priority to IN2484MUN2014 priority patent/IN2014MN02484A/en
Publication of ITMI20121109A1 publication Critical patent/ITMI20121109A1/it

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing carboxylic groups or thio analogues thereof, directly attached by the carbon atom to a cycloaliphatic ring; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing keto or thioketo groups as part of a ring, e.g. cyclohexanone, quinone; Derivatives thereof, e.g. ketals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pest Control & Pesticides (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT001109A 2012-06-25 2012-06-25 Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici ITMI20121109A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT001109A ITMI20121109A1 (it) 2012-06-25 2012-06-25 Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici
EP13744788.4A EP2863904B1 (en) 2012-06-25 2013-06-25 Use of gascardic acid as antibiotic and antifungal adjuvant
CN201380042898.2A CN104540503A (zh) 2012-06-25 2013-06-25 包括二倍半萜的组合物及其作为抗生素佐剂和抗真菌剂佐剂的用途
PCT/IB2013/001360 WO2014001882A1 (en) 2012-06-25 2013-06-25 Composition comprising a sesterterpene and use thereof as antibiotic and antifungal adjuvant
US14/408,553 US9775348B2 (en) 2012-06-25 2013-06-25 Composition comprising a sesterterpene and use thereof as antibiotic and antifungal adjuvant
IN2484MUN2014 IN2014MN02484A (2) 2012-06-25 2013-06-25

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001109A ITMI20121109A1 (it) 2012-06-25 2012-06-25 Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici

Publications (1)

Publication Number Publication Date
ITMI20121109A1 true ITMI20121109A1 (it) 2013-12-26

Family

ID=46690597

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001109A ITMI20121109A1 (it) 2012-06-25 2012-06-25 Composizione comprendente acido gascardico o un suo derivato e relativo uso come coadiuvante per antibiotici

Country Status (6)

Country Link
US (1) US9775348B2 (2)
EP (1) EP2863904B1 (2)
CN (1) CN104540503A (2)
IN (1) IN2014MN02484A (2)
IT (1) ITMI20121109A1 (2)
WO (1) WO2014001882A1 (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940211B (zh) * 2015-06-08 2018-06-19 广州万粤知识产权运营有限公司 白桦脂酸在制备抗真菌生物被膜药物中的应用
CN108516923B (zh) * 2018-05-22 2019-06-25 天津汉荣生物技术有限公司 一系列烯萜类化合物及其制备方法和应用
US12171748B2 (en) 2018-05-29 2024-12-24 IRP Health Pty Ltd Nitroimidazole formulations
CN109662967B (zh) * 2019-02-19 2021-02-12 孙益虎 一种抗抑郁药物及其用途
CN110507660A (zh) * 2019-09-24 2019-11-29 吉林大学 五环三萜类化合物在制备细菌性溶血素抑制剂中的用途
CN111658683A (zh) * 2020-05-15 2020-09-15 广东药科大学 诃子提取物在制备马拉色菌抑制剂中的应用
CN114224876B (zh) * 2021-11-03 2023-04-07 中南民族大学 二倍半萜类化合物的制备方法及其在抗临床耐药细菌方面的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270344A (en) * 1988-06-24 1993-12-14 Stephen Herman Method of treating a systemic disorder using trioxolane and diperoxide compounds
US5190979A (en) * 1988-06-24 1993-03-02 Stephen Herman Ozonides of terpenes and their medical uses
JP2004509972A (ja) * 2000-09-29 2004-04-02 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 酵母に対する殺真菌活性を有するトリテルペン

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BAAS ET AL: "Naturally occurring seco-ring-A-triterpenoids and their possible biological significance", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 24, no. 9, 1 January 1985 (1985-01-01), pages 1875 - 1889, XP026617013, ISSN: 0031-9422, [retrieved on 19850101], DOI: 10.1016/S0031-9422(00)83085-X *
BOECKMAN ROBERT K JR ET AL: "A total synthesis of gascardic acid", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ACS PUBLICATIONS, US, vol. 101, no. 17, 1 August 1979 (1979-08-01), pages 5060 - 5062, XP009163435, ISSN: 0002-7863 *
FLEKHTER O B ET AL: "Synthesis of betulinic acid from betulin extract and study of the antiviral and antiulcer activity of some related terpenoids", PHARMACEUTICAL CHEMISTRY JOURNAL 20020901 US LNKD- DOI:10.1023/A:1021844705853, vol. 36, no. 9, 1 September 2002 (2002-09-01), pages 484 - 487, XP002684912, ISSN: 0091-150X *
LIU M ET AL: "Phytochemical and antifungal studies on Terminalia mollis and Terminalia brachystemma", FITOTERAPIA, IDB HOLDING, MILAN, IT, vol. 80, no. 6, 1 September 2009 (2009-09-01), pages 369 - 373, XP026319368, ISSN: 0367-326X, [retrieved on 20090514], DOI: 10.1016/J.FITOTE.2009.05.006 *

Also Published As

Publication number Publication date
CN104540503A (zh) 2015-04-22
IN2014MN02484A (2) 2015-07-10
US9775348B2 (en) 2017-10-03
WO2014001882A1 (en) 2014-01-03
US20150196029A1 (en) 2015-07-16
EP2863904A1 (en) 2015-04-29
EP2863904B1 (en) 2018-02-21

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