ITMI940031A0 - Processo per la produzione dell'enzima acido 78-(4-carbossibutanamido)-cefalosporanico acilasi - Google Patents

Processo per la produzione dell'enzima acido 78-(4-carbossibutanamido)-cefalosporanico acilasi

Info

Publication number
ITMI940031A0
ITMI940031A0 ITMI940031A ITMI940031A ITMI940031A0 IT MI940031 A0 ITMI940031 A0 IT MI940031A0 IT MI940031 A ITMI940031 A IT MI940031A IT MI940031 A ITMI940031 A IT MI940031A IT MI940031 A0 ITMI940031 A0 IT MI940031A0
Authority
IT
Italy
Prior art keywords
acilase
carboxybutanamido
cephalosporanic
enzyme
production
Prior art date
Application number
ITMI940031A
Other languages
English (en)
Inventor
Der Goes Wilhelmus Van
Pietro Cesti
Antonella Bernardi
Aldo Bosetti
Giuliana Franzosi
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Publication of ITMI940031A0 publication Critical patent/ITMI940031A0/it
Priority to ITMI940031A priority Critical patent/IT1269180B/it
Priority to US08/366,457 priority patent/US5612210A/en
Priority to EP95200057A priority patent/EP0663445B1/en
Priority to AT95200057T priority patent/ATE179755T1/de
Priority to DK95200057T priority patent/DK0663445T3/da
Priority to ES95200057T priority patent/ES2132511T3/es
Priority to DE69509417T priority patent/DE69509417T2/de
Priority to JP7019867A priority patent/JP2805594B2/ja
Publication of ITMI940031A1 publication Critical patent/ITMI940031A1/it
Priority to US08/712,389 priority patent/US5801048A/en
Application granted granted Critical
Publication of IT1269180B publication Critical patent/IT1269180B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
ITMI940031A 1994-01-14 1994-01-14 Processo per la produzione dell'enzima acido 7beta- (4-carbossibutanamido)-cefalosporanico acilasi IT1269180B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI940031A IT1269180B (it) 1994-01-14 1994-01-14 Processo per la produzione dell'enzima acido 7beta- (4-carbossibutanamido)-cefalosporanico acilasi
US08/366,457 US5612210A (en) 1994-01-14 1994-12-30 Process for producing 7β-(4-carboxybutanamido)-cephalosporanic acid acylase ("GA") enzyme
DK95200057T DK0663445T3 (da) 1994-01-14 1995-01-11 Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym
AT95200057T ATE179755T1 (de) 1994-01-14 1995-01-11 Herstellungsverfahren des enzyms 7beta-(4-carboxy-butanamido)-cephalosporanische säureacylase
EP95200057A EP0663445B1 (en) 1994-01-14 1995-01-11 Process for producing 7beta-(4-carboxybutanamido)-cephalosporanic acid acylase ("GA) enzyme
ES95200057T ES2132511T3 (es) 1994-01-14 1995-01-11 Procedimiento para la produccion de la enzima acido 7beta-(4-carboxibutanamido)-cefalosporanico-acilasa ("ga").
DE69509417T DE69509417T2 (de) 1994-01-14 1995-01-11 Herstellungsverfahren des Enzyms 7beta-(4-carboxy-butanamido)-cephalosporanischen Säureacylase
JP7019867A JP2805594B2 (ja) 1994-01-14 1995-01-13 ７−（４−カルボキシブタンアミド）−セファロスポラン酸アシラーゼの製法
US08/712,389 US5801048A (en) 1994-01-14 1996-09-11 Process for producing 7B-(4-carboxybutanamido)-cephalosporanic acid acylase ("GA") enzyme

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI940031A IT1269180B (it) 1994-01-14 1994-01-14 Processo per la produzione dell'enzima acido 7beta- (4-carbossibutanamido)-cefalosporanico acilasi

Publications (3)

Publication Number Publication Date
ITMI940031A0 true ITMI940031A0 (it) 1994-01-14
ITMI940031A1 ITMI940031A1 (it) 1995-07-14
IT1269180B IT1269180B (it) 1997-03-21

Family

ID=11367491

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940031A IT1269180B (it) 1994-01-14 1994-01-14 Processo per la produzione dell'enzima acido 7beta- (4-carbossibutanamido)-cefalosporanico acilasi

Country Status (8)

Country Link
US (2) US5612210A (it)
EP (1) EP0663445B1 (it)
JP (1) JP2805594B2 (it)
AT (1) ATE179755T1 (it)
DE (1) DE69509417T2 (it)
DK (1) DK0663445T3 (it)
ES (1) ES2132511T3 (it)
IT (1) IT1269180B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766871A (en) * 1996-11-27 1998-06-16 Food Industry Research And Development Institute Screening and characterization of glutaryl-7-aminocephalosporanic acid acylase
KR100481138B1 (ko) * 1997-09-09 2005-04-11 바이오케미 게젤샤프트 엠베하 효소 활성을 갖는 미생물을 함유하는 구형 입자 및 구형 입자의 제조방법
FR3094492A1 (fr) * 2019-04-01 2020-10-02 Polyneuros Procédé de détection ou de suivi de l’évolution d’une maladie chronique dégénérative par dosage immunologique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2464298A1 (fr) * 1979-09-04 1981-03-06 Roquette Freres Procede de trempage du mais, produits ainsi obtenus et leur application a la fabrication de la penicilline
US4440792A (en) * 1982-09-07 1984-04-03 A. E. Staley Manufacturing Company Method for preventing gelation of corn steep liquor
ES2020792A6 (es) * 1990-08-03 1991-09-16 Antibioticos Sa Un procedimiento enzimatico para la presentacion de acido 7-amino-cefa-losporanico y un procedimiento para expresar la enzima 7b (4-carboxibutanamido) cefalosporinacilasa.
DE4136389A1 (de) * 1991-03-18 1992-10-08 Hoechst Ag Verfahren zur herstellung von glutarylacylase in grossen mengen

Also Published As

Publication number Publication date
ES2132511T3 (es) 1999-08-16
JP2805594B2 (ja) 1998-09-30
EP0663445B1 (en) 1999-05-06
IT1269180B (it) 1997-03-21
ATE179755T1 (de) 1999-05-15
EP0663445A1 (en) 1995-07-19
JPH07303483A (ja) 1995-11-21
DK0663445T3 (da) 1999-11-01
DE69509417T2 (de) 1999-12-16
US5801048A (en) 1998-09-01
DE69509417D1 (de) 1999-06-10
US5612210A (en) 1997-03-18
ITMI940031A1 (it) 1995-07-14

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Legal Events

Date Code Title Description
0001 Granted