ITMI941191A0 - 1-b-metil-2-tiol carbapen derivati - Google Patents

1-b-metil-2-tiol carbapen derivati

Info

Publication number
ITMI941191A0
ITMI941191A0 ITMI941191A ITMI941191A ITMI941191A0 IT MI941191 A0 ITMI941191 A0 IT MI941191A0 IT MI941191 A ITMI941191 A IT MI941191A IT MI941191 A ITMI941191 A IT MI941191A IT MI941191 A0 ITMI941191 A0 IT MI941191A0
Authority
IT
Italy
Prior art keywords
carbapen
thiol
derivatives
methyl
thiol carbapen
Prior art date
Application number
ITMI941191A
Other languages
English (en)
Inventor
Hyuck Cho Jung
Hyun Oh Chang
Hong Nam Ki
Original Assignee
Dong Kook Pharm Co Ltd
Ki Beom Kwon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Kook Pharm Co Ltd, Ki Beom Kwon filed Critical Dong Kook Pharm Co Ltd
Publication of ITMI941191A0 publication Critical patent/ITMI941191A0/it
Publication of ITMI941191A1 publication Critical patent/ITMI941191A1/it
Application granted granted Critical
Publication of IT1270183B publication Critical patent/IT1270183B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ITMI941191A 1993-06-15 1994-06-08 1-b-metil-2-tiol carbapen derivati IT1270183B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR930010878 1993-06-15
US08/155,477 US5463046A (en) 1993-06-15 1993-11-19 1-β-methyl-2-thiolic carbapenem derivatives

Publications (3)

Publication Number Publication Date
ITMI941191A0 true ITMI941191A0 (it) 1994-06-08
ITMI941191A1 ITMI941191A1 (it) 1995-12-08
IT1270183B IT1270183B (it) 1997-04-29

Family

ID=26629717

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI941191A IT1270183B (it) 1993-06-15 1994-06-08 1-b-metil-2-tiol carbapen derivati

Country Status (13)

Country Link
US (1) US5463046A (it)
JP (1) JP2531489B2 (it)
KR (1) KR950000700A (it)
CN (1) CN1100100A (it)
AU (1) AU4912393A (it)
BR (1) BR9400695A (it)
CA (1) CA2102003A1 (it)
DE (1) DE4335984A1 (it)
ES (1) ES2070790B1 (it)
FR (1) FR2706460A1 (it)
GB (1) GB2279073A (it)
IT (1) IT1270183B (it)
NL (1) NL9301877A (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2099817A1 (en) * 1992-07-21 1994-01-22 Frederic H. Jung Antibiotic compounds
EP0882728B1 (en) * 1995-12-21 2002-09-04 Sankyo Company Limited 1-methylcarbapenem derivatives
KR100309703B1 (ko) * 1999-01-18 2001-10-29 박호군 이중고리 티올 유도체, 이를 치환기로 갖는 1-β-메틸-카바페넴 유도체, 및 그들의 제조방법
CN101260108B (zh) * 2007-03-11 2010-06-02 山东轩竹医药科技有限公司 巯基吡咯烷酮碳青霉烯类衍生物
US10695322B2 (en) 2016-01-29 2020-06-30 The Johns Hopkins University Inhibitors of bacterial growth

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60233076A (ja) * 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
DE3780344T2 (de) * 1986-03-27 1993-01-28 Sumitomo Pharma Beta-lactam-verbindungen und deren herstellung.
DE3784147T2 (de) * 1986-11-24 1993-06-03 Fujisawa Pharmaceutical Co 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-en-2-carbonsaeure-derivate.
DE68919508T2 (de) * 1988-04-01 1995-07-20 Sankyo Co 2-(Heterocyclylthio)carbapenemderivate, deren Herstellung und deren Verwendung als Antibiotika.
CA2022382A1 (en) * 1989-08-02 1991-02-03 Susumu Nakagawa Piperidylthiocarbapenem derivatives
US5227376A (en) * 1990-02-14 1993-07-13 Sumitomo Pharmaceuticals Co., Ltd. β-lactam compounds and their production
CA2036163C (en) * 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production
CA2036941A1 (en) * 1990-02-23 1991-08-24 Isao Kawamoto Carbapenem derivatives having antibiotic activity, their preparation and their use
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
GB9107341D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
FI101226B1 (fi) * 1991-06-04 1998-05-15 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 2-[2-(karbonyyli)pyrrolidin-4-yylitio]-6-(1-hydroksietyyli)-1-metyylikarbapen-2-eemi-3-karboksyylihappojohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
BR9400695A (pt) 1995-01-10
JPH06345766A (ja) 1994-12-20
KR950000700A (ko) 1995-01-03
NL9301877A (nl) 1995-01-02
ES2070790A1 (es) 1995-06-01
CN1100100A (zh) 1995-03-15
CA2102003A1 (en) 1994-12-16
US5463046A (en) 1995-10-31
FR2706460A1 (fr) 1994-12-23
IT1270183B (it) 1997-04-29
ES2070790B1 (es) 1996-03-16
DE4335984A1 (de) 1994-12-22
ITMI941191A1 (it) 1995-12-08
GB2279073A (en) 1994-12-21
JP2531489B2 (ja) 1996-09-04
AU4912393A (en) 1994-12-22
GB9411844D0 (en) 1994-08-03

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Legal Events

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0001 Granted