ITMI992070A0 - Processo per la purificazione di s-adenosil-l-metionina e per la prepa razione dei suoi sali farmaceuticamente accettabili - Google Patents

Processo per la purificazione di s-adenosil-l-metionina e per la prepa razione dei suoi sali farmaceuticamente accettabili

Info

Publication number
ITMI992070A0
ITMI992070A0 IT99MI002070A ITMI992070A ITMI992070A0 IT MI992070 A0 ITMI992070 A0 IT MI992070A0 IT 99MI002070 A IT99MI002070 A IT 99MI002070A IT MI992070 A ITMI992070 A IT MI992070A IT MI992070 A0 ITMI992070 A0 IT MI992070A0
Authority
IT
Italy
Prior art keywords
adenosyl
methionine
purification
preparation
pharmaceutically acceptable
Prior art date
Application number
IT99MI002070A
Other languages
English (en)
Inventor
Franco Polastri
Gianni Santambrogio
Original Assignee
Chementecno Srl
Gnosis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chementecno Srl, Gnosis Srl filed Critical Chementecno Srl
Priority to IT1999MI002070A priority Critical patent/IT1315236B1/it
Publication of ITMI992070A0 publication Critical patent/ITMI992070A0/it
Priority to EP00120521A priority patent/EP1091001B1/en
Priority to DE60022960T priority patent/DE60022960T2/de
Priority to DK00120521T priority patent/DK1091001T3/da
Priority to AT00120521T priority patent/ATE305978T1/de
Priority to ES00120521T priority patent/ES2249221T3/es
Priority to CA002322231A priority patent/CA2322231C/en
Publication of ITMI992070A1 publication Critical patent/ITMI992070A1/it
Application granted granted Critical
Publication of IT1315236B1 publication Critical patent/IT1315236B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT1999MI002070A 1999-10-05 1999-10-05 Processo per la purificazione di s-adenosil-l-metionina e per lapreparazione dei suoi sali farmaceuticamente accettabili. IT1315236B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT1999MI002070A IT1315236B1 (it) 1999-10-05 1999-10-05 Processo per la purificazione di s-adenosil-l-metionina e per lapreparazione dei suoi sali farmaceuticamente accettabili.
EP00120521A EP1091001B1 (en) 1999-10-05 2000-09-20 Process for the purification of S-adenosyl-L-methionine and for the preparation of the pharmaceutically acceptable salts thereof
DE60022960T DE60022960T2 (de) 1999-10-05 2000-09-20 Verfahren für die Aufreinigung von S-Adenosyl-L-methionin und für die Herstellung von pharmazeutisch annehmbaren Salzen davon
DK00120521T DK1091001T3 (da) 1999-10-05 2000-09-20 Fremgangsmåde til rensning af S-adenosyl-L-methionin og til fremstilling af farmaceutiske acceptable salte deraf
AT00120521T ATE305978T1 (de) 1999-10-05 2000-09-20 Verfahren zur reinigung von s-adenosyl-l- methionin und zur herstellung von pharmazeutisch verträglichen salzen davon
ES00120521T ES2249221T3 (es) 1999-10-05 2000-09-20 Procedimiento para la purificacion de s-adenosil-l-metionina y para la preparacion de sus sales farmaceuticamente aceptables.
CA002322231A CA2322231C (en) 1999-10-05 2000-10-04 Process for the purification of s-adenosyl-l-methionine and for the preparation of the pharmaceutically acceptable salts thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002070A IT1315236B1 (it) 1999-10-05 1999-10-05 Processo per la purificazione di s-adenosil-l-metionina e per lapreparazione dei suoi sali farmaceuticamente accettabili.

Publications (3)

Publication Number Publication Date
ITMI992070A0 true ITMI992070A0 (it) 1999-10-05
ITMI992070A1 ITMI992070A1 (it) 2001-04-05
IT1315236B1 IT1315236B1 (it) 2003-02-03

Family

ID=11383720

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI002070A IT1315236B1 (it) 1999-10-05 1999-10-05 Processo per la purificazione di s-adenosil-l-metionina e per lapreparazione dei suoi sali farmaceuticamente accettabili.

Country Status (7)

Country Link
EP (1) EP1091001B1 (it)
AT (1) ATE305978T1 (it)
CA (1) CA2322231C (it)
DE (1) DE60022960T2 (it)
DK (1) DK1091001T3 (it)
ES (1) ES2249221T3 (it)
IT (1) IT1315236B1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005009751A1 (de) 2005-03-03 2006-09-07 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen Herstellung von S-Adenosyl-Methionin
WO2007083631A1 (ja) 2006-01-17 2007-07-26 Mitsubishi Gas Chemical Company, Inc. Ｓ－アデノシル－ｌ－メチオニンの安定化法及び安定化された組成物
WO2007132831A1 (ja) 2006-05-16 2007-11-22 Mitsubishi Gas Chemical Company, Inc. 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及び経口摂取用組成物
WO2008090905A1 (ja) 2007-01-25 2008-07-31 Mitsubishi Gas Chemical Company, Inc. 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物
CN102321136B (zh) * 2011-09-19 2014-10-22 北京化工大学 S-腺苷-l-甲硫氨酸对甲苯磺酸硫酸双盐的制备方法
CN104211744A (zh) * 2013-05-30 2014-12-17 北京东方瑞德生物技术有限公司 一种s-腺苷蛋氨酸对甲苯磺酸硫酸盐的制备方法
CN109456377A (zh) * 2018-12-17 2019-03-12 山东金城生物药业有限公司 一种腺苷蛋氨酸盐的制备方法
CN110396120B (zh) * 2019-02-13 2020-05-12 山东惠仕莱生物科技有限公司 一种从s-腺苷蛋氨酸发酵液中提取分离s-腺苷蛋氨酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1803978C2 (de) * 1968-10-18 1985-05-02 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Gewinnung von S-Adenosyl-l-methionin und S-Adenosyl-l-ethionin
US3962034A (en) * 1973-02-01 1976-06-08 Ajinomoto Co., Inc. Method for producing s-adenosylmethionine or methylthioadenosine by yeast
US4028183A (en) * 1973-06-27 1977-06-07 Bioresearch Limited Process of preparing double salts of S-adenosyl-L-methionine
GB2116172B (en) * 1982-02-25 1986-07-09 Nippon Zeon Co Microbial cells containing s-adenosyl methionine in high concentrations and process for production of s adenosyl methionine
IT1169773B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Processo per la produzione di sali stabili della solfo-adenosil-l-metionina

Also Published As

Publication number Publication date
EP1091001B1 (en) 2005-10-05
DE60022960T2 (de) 2006-06-29
ES2249221T3 (es) 2006-04-01
DE60022960D1 (de) 2006-02-16
DK1091001T3 (da) 2005-11-14
CA2322231C (en) 2009-03-17
IT1315236B1 (it) 2003-02-03
EP1091001A1 (en) 2001-04-11
ITMI992070A1 (it) 2001-04-05
CA2322231A1 (en) 2001-04-05
ATE305978T1 (de) 2005-10-15

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