ITPD920146A0 - Nuovi derivati dell'acido neuraminico - Google Patents
Nuovi derivati dell'acido neuraminicoInfo
- Publication number
- ITPD920146A0 ITPD920146A0 IT92PD146A ITPD920146A ITPD920146A0 IT PD920146 A0 ITPD920146 A0 IT PD920146A0 IT 92PD146 A IT92PD146 A IT 92PD146A IT PD920146 A ITPD920146 A IT PD920146A IT PD920146 A0 ITPD920146 A0 IT PD920146A0
- Authority
- IT
- Italy
- Prior art keywords
- neuraminic acid
- new derivatives
- derivatives
- new
- neuraminic
- Prior art date
Links
- CERZMXAJYMMUDR-QBTAGHCHSA-N 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid Chemical class N[C@@H]1[C@@H](O)CC(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO CERZMXAJYMMUDR-QBTAGHCHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD920146A IT1260156B (it) | 1992-08-03 | 1992-08-03 | Derivati dell'acido neuraminico |
| CA002141679A CA2141679C (en) | 1992-08-03 | 1993-08-03 | New derivatives of neuraminic acid |
| JP6505524A JPH08502953A (ja) | 1992-08-03 | 1993-08-03 | ノイラミン酸の新規誘導体 |
| PCT/US1993/007307 WO1994003469A1 (en) | 1992-08-03 | 1993-08-03 | New derivatives of neuraminic acid |
| AU48014/93A AU4801493A (en) | 1992-08-03 | 1993-08-03 | New derivatives of neuraminic acid |
| EP93918621A EP0652887A1 (en) | 1992-08-03 | 1993-08-03 | New derivatives of neuraminic acid |
| US08/379,602 US5677285A (en) | 1992-08-03 | 1993-08-03 | Derivatives of neuraminic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD920146A IT1260156B (it) | 1992-08-03 | 1992-08-03 | Derivati dell'acido neuraminico |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITPD920146A0 true ITPD920146A0 (it) | 1992-08-03 |
| ITPD920146A1 ITPD920146A1 (it) | 1994-02-03 |
| IT1260156B IT1260156B (it) | 1996-03-28 |
Family
ID=11390038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITPD920146A IT1260156B (it) | 1992-08-03 | 1992-08-03 | Derivati dell'acido neuraminico |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0652887A1 (it) |
| JP (1) | JPH08502953A (it) |
| AU (1) | AU4801493A (it) |
| CA (1) | CA2141679C (it) |
| IT (1) | IT1260156B (it) |
| WO (1) | WO1994003469A1 (it) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW479061B (en) * | 1993-12-24 | 2002-03-11 | Mitsubishi Chem Corp | Sialic acid derivatives |
| US5783564A (en) * | 1993-12-24 | 1998-07-21 | Mitsubishi Chemical Corporation | Sialic acid derivatives |
| IT1271624B (it) * | 1994-03-21 | 1997-06-04 | Lifegroup Spa | Derivati glucosidici di n-acil alchilamine capaci di esercitare effetto o neuroprotettivo utilizzabili nelle patologie acute e croniche del sistema nervoso centrale correlate ad eccitotossicita' |
| US5849709A (en) * | 1995-05-10 | 1998-12-15 | Glycomed Incorporated | Saccharopeptides and derivatives thereof |
| WO1997000885A1 (fr) | 1995-06-23 | 1997-01-09 | Mitsubishi Chemical Corporation | Derives d'acide sialique |
| US5824662A (en) * | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| CA2264043A1 (en) | 1996-09-27 | 1998-04-02 | Guilford Pharmaceuticals Inc. | Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals |
| US6444649B1 (en) | 1998-04-10 | 2002-09-03 | Mitsubishi Chemical Corporation | Solid dispersion containing sialic acid derivative |
| CN1523994A (zh) * | 2001-05-23 | 2004-08-25 | 钱吉子 | 一种用于预防和/或治疗痴呆的以灵芝提取物、十八碳烯酰胺及其衍生物作为有效成分的组合物 |
| JP4005115B1 (ja) * | 2007-02-08 | 2007-11-07 | 日本臓器製薬株式会社 | 疼痛疾患治療剤 |
| JP5327839B2 (ja) * | 2008-06-09 | 2013-10-30 | 国立大学法人埼玉大学 | シアル酸誘導体の製造方法とインフルエンザウィルス阻害剤としての利用 |
| JP5298390B2 (ja) * | 2009-11-19 | 2013-09-25 | 学校法人福岡大学 | フルオラス化シアル酸誘導体およびその分析方法 |
| TWI599354B (zh) | 2016-08-10 | 2017-09-21 | 國立臺灣師範大學 | 四氫吡喃醇衍生化合物用於製備Tau蛋白病變類疾病之醫藥組成物上之用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3014027A (en) * | 1956-01-20 | 1961-12-19 | Ciba Pharm Prod Inc | N-acylamino compounds |
| IL41409A (en) * | 1972-02-04 | 1977-04-29 | Richter Gedeon Vegyeszet | Lysergic acid amides and process for their preparation |
| JPS60231690A (ja) * | 1984-05-01 | 1985-11-18 | Kanto Ishi Pharma Co Ltd | N―置換ノイラミン酸誘導体 |
| NL194729C (nl) * | 1986-10-13 | 2003-01-07 | Novartis Ag | Werkwijze voor de bereiding van peptidealcoholen via vaste fase. |
| JPH03151398A (ja) * | 1989-11-06 | 1991-06-27 | Mect Corp | シアル酸結合生理活性ペプチド及びその製造方法 |
-
1992
- 1992-08-03 IT ITPD920146A patent/IT1260156B/it active IP Right Grant
-
1993
- 1993-08-03 AU AU48014/93A patent/AU4801493A/en not_active Abandoned
- 1993-08-03 WO PCT/US1993/007307 patent/WO1994003469A1/en not_active Ceased
- 1993-08-03 JP JP6505524A patent/JPH08502953A/ja active Pending
- 1993-08-03 EP EP93918621A patent/EP0652887A1/en not_active Withdrawn
- 1993-08-03 CA CA002141679A patent/CA2141679C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2141679A1 (en) | 1994-02-17 |
| AU4801493A (en) | 1994-03-03 |
| WO1994003469A1 (en) | 1994-02-17 |
| CA2141679C (en) | 2000-09-19 |
| IT1260156B (it) | 1996-03-28 |
| ITPD920146A1 (it) | 1994-02-03 |
| EP0652887A1 (en) | 1995-05-17 |
| JPH08502953A (ja) | 1996-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19990614 |