ITMI931649A0 - Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico - Google Patents

Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico

Info

Publication number
ITMI931649A0
ITMI931649A0 IT93MI1649A ITMI931649A ITMI931649A0 IT MI931649 A0 ITMI931649 A0 IT MI931649A0 IT 93MI1649 A IT93MI1649 A IT 93MI1649A IT MI931649 A ITMI931649 A IT MI931649A IT MI931649 A0 ITMI931649 A0 IT MI931649A0
Authority
IT
Italy
Prior art keywords
phenyl
derivatives
amino
butyric acid
oxo butyric
Prior art date
Application number
IT93MI1649A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ITMI931649A0 publication Critical patent/ITMI931649A0/it
Priority to IT93MI001649A priority Critical patent/IT1265101B1/it
Priority to PCT/EP1994/002280 priority patent/WO1995003271A1/en
Priority to SI9430206T priority patent/SI0662948T1/xx
Priority to NZ268896A priority patent/NZ268896A/en
Priority to FI951298A priority patent/FI951298L/fi
Priority to ES94921642T priority patent/ES2123801T3/es
Priority to JP7503289A priority patent/JPH08501805A/ja
Priority to AU72285/94A priority patent/AU678273B2/en
Priority to KR1019950701103A priority patent/KR950703517A/ko
Priority to AT94921642T priority patent/ATE171935T1/de
Priority to DE69413789T priority patent/DE69413789T2/de
Priority to EP94921642A priority patent/EP0662948B1/en
Priority to HU9501146A priority patent/HUT70478A/hu
Priority to CA002144521A priority patent/CA2144521A1/en
Priority to PL94308142A priority patent/PL179857B1/pl
Priority to DK94921642T priority patent/DK0662948T3/da
Priority to RU95111308A priority patent/RU2139850C1/ru
Priority to CN94190531A priority patent/CN1112786A/zh
Priority to IL110365A priority patent/IL110365A/en
Priority to TW083106674A priority patent/TW268937B/zh
Priority to ZA945425A priority patent/ZA945425B/xx
Publication of ITMI931649A1 publication Critical patent/ITMI931649A1/it
Priority to NO951100A priority patent/NO951100L/no
Application granted granted Critical
Publication of IT1265101B1 publication Critical patent/IT1265101B1/it
Priority to US08/949,392 priority patent/US20010008947A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT93MI001649A 1993-07-23 1993-07-23 Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico IT1265101B1 (it)

Priority Applications (23)

Application Number Priority Date Filing Date Title
IT93MI001649A IT1265101B1 (it) 1993-07-23 1993-07-23 Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico
HU9501146A HUT70478A (en) 1993-07-23 1994-07-12 Process to prepare 2-amino-4-phenyl-4-oxo-butyric acid derivatives and pharmaceutical compositions contg. them with activity against neurodegenerative diseases
PL94308142A PL179857B1 (pl) 1993-07-23 1994-07-12 Pochodne kwasu 2-amino-4-fenylo-4-okso-maslowego, sposób ich wytwarzania oraz zawierajaca je kompozycja farmaceutyczna PL PL PL PL PL PL
NZ268896A NZ268896A (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives and pharmaceutical compositions thereof
FI951298A FI951298L (fi) 1993-07-23 1994-07-12 2-amino-4-fenyyli-4-oksovoihappojohdannaiset, joilla on kynureninaasia ja/tai kynureniini-3-hydroksylaasia inhiboiva aktiivisuus
ES94921642T ES2123801T3 (es) 1993-07-23 1994-07-12 Derivados de acido 2-amino-4-fenil-4-oxo-butirico con actividad inhibidora de quinureninasa y/o quinurenina-3-hidroxilasa.
JP7503289A JPH08501805A (ja) 1993-07-23 1994-07-12 キヌレニナーゼおよび／またはキヌレニン−３−ヒドロキシラーゼ阻害活性を有する２−アミノ−４−フェニル−４−オキソ酪酸誘導体
AU72285/94A AU678273B2 (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity
KR1019950701103A KR950703517A (ko) 1993-07-23 1994-07-12 키누레니나제 및/또는 키누레닌-3-하이드록실라제 억제 활성을 갖는 2-아미노-4-페닐-4-옥소-부티르산 유도체(2-Amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity)
AT94921642T ATE171935T1 (de) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-buttersäure-derivate mit kynureninase und/oder kynurenin-3-hydroxylase inhibierender wirkung
DE69413789T DE69413789T2 (de) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-buttersäure-derivate mit kynureninase und/oder kynurenin-3-hydroxylase inhibierender wirkung
EP94921642A EP0662948B1 (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity
PCT/EP1994/002280 WO1995003271A1 (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity
CA002144521A CA2144521A1 (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity
SI9430206T SI0662948T1 (en) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxo-butyric acid derivatives with kynureninase and/or kynurenine-3-hydroxylase inhibiting activity
DK94921642T DK0662948T3 (da) 1993-07-23 1994-07-12 2-amino-4-phenyl-4-oxosmørsyrederivater med kynureninase- og/eller kynurenin-3-hydroxylaseinhiberende virkning
RU95111308A RU2139850C1 (ru) 1993-07-23 1994-07-12 Производные 2-амино-4-фенил-4-оксомасляной кислоты и фармацевтическая композиция
CN94190531A CN1112786A (zh) 1993-07-23 1994-07-12 2-氨基-4-苯基-4-氧代丁酸衍生物
IL110365A IL110365A (en) 1993-07-23 1994-07-19 2-amino-4-phenyl-4-oxo- butyric acid derivatives, their preparation and pharmaceutical compositions containing them
TW083106674A TW268937B (it) 1993-07-23 1994-07-21
ZA945425A ZA945425B (en) 1993-07-23 1994-07-22 2-amino-4-phenyl-4-oxo-butyric acid derivatives
NO951100A NO951100L (no) 1993-07-23 1995-03-22 2-amino-4-fenyl-4-oksosmörsyrederivater med kynurinase- og/eller kynurenin-3-hydroksylase-inhiberende aktivitet
US08/949,392 US20010008947A1 (en) 1993-07-23 1997-10-14 2-amino-4-phenyl-4-oxo-butyric acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001649A IT1265101B1 (it) 1993-07-23 1993-07-23 Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico

Publications (3)

Publication Number Publication Date
ITMI931649A0 true ITMI931649A0 (it) 1993-07-23
ITMI931649A1 ITMI931649A1 (it) 1995-01-23
IT1265101B1 IT1265101B1 (it) 1996-10-30

Family

ID=11366678

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001649A IT1265101B1 (it) 1993-07-23 1993-07-23 Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico

Country Status (21)

Country Link
US (1) US20010008947A1 (it)
EP (1) EP0662948B1 (it)
JP (1) JPH08501805A (it)
KR (1) KR950703517A (it)
CN (1) CN1112786A (it)
AT (1) ATE171935T1 (it)
AU (1) AU678273B2 (it)
CA (1) CA2144521A1 (it)
DE (1) DE69413789T2 (it)
DK (1) DK0662948T3 (it)
ES (1) ES2123801T3 (it)
FI (1) FI951298L (it)
HU (1) HUT70478A (it)
IL (1) IL110365A (it)
IT (1) IT1265101B1 (it)
NZ (1) NZ268896A (it)
PL (1) PL179857B1 (it)
RU (1) RU2139850C1 (it)
TW (1) TW268937B (it)
WO (1) WO1995003271A1 (it)
ZA (1) ZA945425B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519055A (en) * 1993-08-06 1996-05-21 University Of Maryland At Baltimore Substituted kynurenines and process for their preparation
US5786508A (en) * 1994-07-15 1998-07-28 Pharmacia & Upjohn S.P.A. Substituted kynurenines and process for their preparation
GB9521486D0 (en) * 1995-10-20 1995-12-20 Pharmacia Spa Fluoro-substituted benzoylpropionic acid derivatives
GB9615441D0 (en) * 1996-07-23 1996-09-04 Pharmacia Spa Benzoylpropionic acid ester derivatives
ATE282602T1 (de) * 1996-08-16 2004-12-15 Warner Lambert Co Buttersäure matrix-metalloproteinase-inhibitoren
GB9618349D0 (en) * 1996-09-03 1996-10-16 Pharmacia Spa N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity
GB9716103D0 (en) * 1997-07-30 1997-10-01 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
GB9725055D0 (en) * 1997-11-26 1998-01-28 Pharmacia & Upjohn Spa 1,3,4-thiadiazoles compounds
GB9725141D0 (en) * 1997-11-27 1998-01-28 Pharmacia & Upjohn Spa Benzenesulfonamide compounds
JP5627160B2 (ja) * 1998-02-23 2014-11-19 サウス、アラバマ、メディカル、サイエンス、ファウンデーションＳｏｕｔｈ Ａｌａｂａｍａ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ Ｆｏｕｎｄａｔｉｏｎ 医薬として用いるインドール−３−プロピオン酸、並びにそれらの塩およびエステル
US6783965B1 (en) * 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
ATE288414T1 (de) * 1998-11-11 2005-02-15 Novartis Pharma Gmbh Herstellung von 2-amino-2(2-(4- alkylphenyl)äthyl)propan-1,3-diolen
CN1144779C (zh) * 1999-03-11 2004-04-07 杭州中美华东制药有限公司 制备2-[2-(4-烷基苯基)-乙基]-2-氨基-丙二醇的方法以及其中制得的中间产物
KR100965201B1 (ko) * 2001-06-12 2010-06-24 웰스테트 테라퓨틱스 코포레이션 대사 질환의 치료용 화합물
FR2827045B1 (fr) * 2001-07-05 2007-08-10 Univ Pasteur Methodes et compositions pour la selection et le developpement de nouveaux agents pharmacologiques ou de nouveaux medicaments
FR2827859B1 (fr) 2001-07-30 2005-09-23 Lipha Derives 4-(arylthio) - ou 4-(heteroarylthio) -butyrique dans la preparation de medicaments destines au traitement du diabete
CN1330774C (zh) * 2002-03-01 2007-08-08 国家人类基因组南方研究中心 犬尿氨酸水解酶多态性及其用途
ITMI20041626A1 (it) * 2004-08-06 2004-11-06 Roberto Pellicciari Inibitori della chinurenina-ammino-trasferasi
CN1309702C (zh) * 2005-10-28 2007-04-11 中国科学院上海有机化学研究所 犬尿氨酸酶的特异性抑制剂l－邻甲氧基苯甲酰基丙氨酸的合成方法
AU2009226975B2 (en) 2008-03-19 2012-09-06 Novartis Ag Process for the preparation of 2-amino-2- [2- (4-C3-C21-alkyl-phenyl)ethyl] propane-1, 3-diols
EP3197466B1 (en) * 2014-09-26 2021-02-17 The University Of British Columbia A combination of kynurenine and antigen presenting cells (apc) as therapeutics and methods for their use in immune modulation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI96313C (fi) * 1990-11-28 1996-06-10 Daiichi Seiyaku Co Menetelmä terapeuttisesti käyttökelpoisten ja optisesti aktiivisten 10-(3-amino-4,4-dialkyyli-1-pyrrolidinyyli)-9-fluori-2,3-dihydro-3(S)-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojen valmistamiseksi
AU643365B2 (en) * 1991-02-28 1993-11-11 Aventisub Ii Inc. NMDA antagonists
EP0581907A1 (en) * 1991-04-18 1994-02-09 The University Of Georgia Research Foundation, Inc. Inhibitors of kynureninase
US5495044A (en) * 1991-04-18 1996-02-27 University Of Georgia Research Foundation, Inc. Inhibitors of kynureninase
GB9325360D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Also Published As

Publication number Publication date
EP0662948A1 (en) 1995-07-19
ES2123801T3 (es) 1999-01-16
PL308142A1 (en) 1995-07-24
DE69413789D1 (de) 1998-11-12
AU678273B2 (en) 1997-05-22
ATE171935T1 (de) 1998-10-15
FI951298A0 (fi) 1995-03-20
WO1995003271A1 (en) 1995-02-02
IL110365A (en) 1998-06-15
JPH08501805A (ja) 1996-02-27
CA2144521A1 (en) 1995-02-02
HUT70478A (en) 1995-10-30
NZ268896A (en) 1997-01-29
HU9501146D0 (en) 1995-06-28
TW268937B (it) 1996-01-21
RU2139850C1 (ru) 1999-10-20
FI951298A7 (fi) 1995-03-20
KR950703517A (ko) 1995-09-20
IT1265101B1 (it) 1996-10-30
PL179857B1 (pl) 2000-11-30
ITMI931649A1 (it) 1995-01-23
DE69413789T2 (de) 1999-05-06
IL110365A0 (en) 1994-10-21
DK0662948T3 (da) 1999-06-21
ZA945425B (en) 1995-03-01
EP0662948B1 (en) 1998-10-07
RU95111308A (ru) 1996-12-27
AU7228594A (en) 1995-02-20
FI951298L (fi) 1995-03-20
CN1112786A (zh) 1995-11-29
US20010008947A1 (en) 2001-07-19

Similar Documents

Publication Publication Date Title
ITMI981836A0 (it) Nuovi derivati dell'acido ialuronico
IT8621143A0 (it) Derivati dell'acido malonico e metodi per la loro sintesi.
ITMI941291A0 (it) Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
FI945776L (fi) Yhden astian menetelmä 3-kinolonikarboksyylihaapojohdannaisten valmistamiseksi
ITMI942156A0 (it) Derivati dell'acido p-amminopropionico ad attivita' fungicida
IT1273471B (it) Derivati dell'acido kojico
IT1157014B (it) Derivati dell'ammidinopiperidina particolarmente utili come medicamenti e procedimento per la loro produzione
ITPD920146A0 (it) Nuovi derivati dell'acido neuraminico
IT1270700B (it) Derivati dell'acido kojico
FI931023A7 (fi) Uusia b-aminohappojohdannaisia
IT8922003A0 (it) Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati
IT1167478B (it) Derivati dell'acido ursodesossicolico
MA23133A1 (fr) Derives d'acide d'acyloxyhexanoique .
IT1271404B (it) Derivati ossimici dell'acido formilfenilacetamido-cefalosporanico
ITMI920018A0 (it) Derivati dell'acido 2,4-diammino-1,3,5-triazinil-6-fosforico
ITMI930749A0 (it) Derivato dell'acido iodesossicolico
ITMI951257A0 (it) Derivati dell'acido fosfinico ad attivita' inibitrice delle metallopeptidasi
ITMI941955A0 (it) "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati"
IT8519335A0 (it) Derivati dell'acido amminopropansolfonico n-sostituiti
ITMI931371A1 (it) Procedimento per la preparazione dell'erdosteina
IT1219733B (it) Derivato dell' acido ursodesossicolico
ITMI951297A0 (it) Processo per la preparazione di derivati dell'acido-metil-2- tiofeneacetico
ITMI930524A1 (it) Derivati dell'acido ursodesossicolico e loro preparazione
FI945119L (fi) Menetelmä 3(S)-metyyliheptaanihapon valmistamiseksi ja välituotteet
ITMI922157A1 (it) Processo per la preparazione di derivati dell'acido pirrolidin- carbossilico

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970626