ITRM20130280A1 - Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico. - Google Patents

Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico.

Info

Publication number
ITRM20130280A1
ITRM20130280A1 IT000280A ITRM20130280A ITRM20130280A1 IT RM20130280 A1 ITRM20130280 A1 IT RM20130280A1 IT 000280 A IT000280 A IT 000280A IT RM20130280 A ITRM20130280 A IT RM20130280A IT RM20130280 A1 ITRM20130280 A1 IT RM20130280A1
Authority
IT
Italy
Prior art keywords
erythrocytes
solution
substances
phosphate
population
Prior art date
Application number
IT000280A
Other languages
English (en)
Italian (it)
Inventor
Luca Benatti
Giovanni Capogrossi
Giovanni Mambrini
Marco Mandolini
Original Assignee
Erydel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erydel Spa filed Critical Erydel Spa
Priority to IT000280A priority Critical patent/ITRM20130280A1/it
Priority to KR1020157035053A priority patent/KR102223080B1/ko
Priority to US14/888,486 priority patent/US10849858B2/en
Priority to AU2014264205A priority patent/AU2014264205B2/en
Priority to SG11201509252QA priority patent/SG11201509252QA/en
Priority to BR112015028278-4A priority patent/BR112015028278B1/pt
Priority to MA38625A priority patent/MA38625B1/fr
Priority to RU2015152801A priority patent/RU2670070C2/ru
Priority to PCT/IB2014/061338 priority patent/WO2014181309A1/fr
Priority to PL14732387.7T priority patent/PL2994117T3/pl
Priority to MX2015015409A priority patent/MX374129B/es
Priority to EP23177290.6A priority patent/EP4338803A3/fr
Priority to PT147323877T priority patent/PT2994117T/pt
Priority to ES14732387T priority patent/ES2950419T3/es
Priority to JP2016512472A priority patent/JP6367314B2/ja
Priority to CN201480026710.XA priority patent/CN105228596B/zh
Priority to CA2911976A priority patent/CA2911976C/fr
Priority to EP14732387.7A priority patent/EP2994117B1/fr
Publication of ITRM20130280A1 publication Critical patent/ITRM20130280A1/it
Priority to PH12015502535A priority patent/PH12015502535B1/en
Priority to CR20150604A priority patent/CR20150604A/es
Priority to IL242503A priority patent/IL242503B/en
Priority to SA515370122A priority patent/SA515370122B1/ar
Priority to US17/083,771 priority patent/US12311059B2/en
Priority to US19/192,075 priority patent/US20250255826A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT000280A 2013-05-10 2013-05-10 Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico. ITRM20130280A1 (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT000280A ITRM20130280A1 (it) 2013-05-10 2013-05-10 Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico.
PT147323877T PT2994117T (pt) 2013-05-10 2014-05-09 Processo para a preparação de eritrócitos carregados com uma ou mais substâncias de interesse farmacêutico e eritrócitos assim obtidos
EP23177290.6A EP4338803A3 (fr) 2013-05-10 2014-05-09 Procédé de préparation d'érythrocytes chargés d'une ou plusieurs substances d'intérêt pharmaceutique et érythrocytes ainsi obtenus
AU2014264205A AU2014264205B2 (en) 2013-05-10 2014-05-09 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
SG11201509252QA SG11201509252QA (en) 2013-05-10 2014-05-09 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
BR112015028278-4A BR112015028278B1 (pt) 2013-05-10 2014-05-09 Processo para a preparação de eritrócitos carregados com uma ou mais substâncias de interesse farmacêutico, eritrócitos carregados com uma ou mais substâncias de interesse farmacêutico, composição farmacêutica e uso terapêutico dos ditos eritrócitos
MA38625A MA38625B1 (fr) 2013-05-10 2014-05-09 Procédé pour la préparation d'érythrocytes chargés d'une ou plusieurs substances d'intérêt pharmaceutique, et érythrocytes ainsi obtenus
US14/888,486 US10849858B2 (en) 2013-05-10 2014-05-09 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
PCT/IB2014/061338 WO2014181309A1 (fr) 2013-05-10 2014-05-09 Procédé pour la préparation d'érythrocytes chargés d'une ou plusieurs substances d'intérêt pharmaceutique, et érythrocytes ainsi obtenus
PL14732387.7T PL2994117T3 (pl) 2013-05-10 2014-05-09 Sposób wytwarzania erytrocytów obciążonych jedną lub większą liczbą substancji będących przedmiotem zainteresowania pod względem farmaceutycznym oraz tak otrzymane erytrocyty
MX2015015409A MX374129B (es) 2013-05-10 2014-05-09 Proceso para la preparación de eritrocitos cargados con una o más sustancias de interés farmacéutico y eritrocitos así obtenidos.
KR1020157035053A KR102223080B1 (ko) 2013-05-10 2014-05-09 하나 이상의 약제학적 관심 물질이 로딩된 적혈구를 제조하는 방법 및 이렇게 하여 수득된 적혈구
RU2015152801A RU2670070C2 (ru) 2013-05-10 2014-05-09 Способ получения эритроцитов, нагруженных одним или несколькими веществами, представляющими фармацевтический интерес, и полученные таким образом эритроциты
EP14732387.7A EP2994117B1 (fr) 2013-05-10 2014-05-09 Procédé pour la préparation d'érythrocytes chargés d'une ou plusieurs substances d'intérêt pharmaceutique, et érythrocytes ainsi obtenus
JP2016512472A JP6367314B2 (ja) 2013-05-10 2014-05-09 １種以上の薬学上重要な物質が装填された赤血球の調製方法およびそのようにして得られた赤血球
CN201480026710.XA CN105228596B (zh) 2013-05-10 2014-05-09 用于制备载有一种或多种制药学感兴趣物质的红细胞的方法和由此得到的红细胞
CA2911976A CA2911976C (fr) 2013-05-10 2014-05-09 Procede pour la preparation d'erythrocytes charges d'une ou plusieurs substances d'interet pharmaceutique, et erythrocytes ainsi obtenus
ES14732387T ES2950419T3 (es) 2013-05-10 2014-05-09 Procedimiento para la preparación de eritrocitos cargados con una o más sustancias de interés farmacéutico y eritrocitos obtenidos de esta manera
PH12015502535A PH12015502535B1 (en) 2013-05-10 2015-11-05 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
CR20150604A CR20150604A (es) 2013-05-10 2015-11-05 Proceso para la preparación de eritrocitos cargados con una o más sustancias de interés farmacéutico y eritrocitos así obtenidos
IL242503A IL242503B (en) 2013-05-10 2015-11-08 A process for preparing red blood cells loaded with the pharmaceutical substances of interest and red blood cells produced according to it
SA515370122A SA515370122B1 (ar) 2013-05-10 2015-11-09 عملية تحضير كريات حمراء محملة بواحدة أو أكثر من المواد ذات الأهمية الصيدلانية، والكريات الحمراء المتحصل عليها بهذه الطريقة
US17/083,771 US12311059B2 (en) 2013-05-10 2020-10-29 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
US19/192,075 US20250255826A1 (en) 2013-05-10 2025-04-28 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000280A ITRM20130280A1 (it) 2013-05-10 2013-05-10 Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico.

Publications (1)

Publication Number Publication Date
ITRM20130280A1 true ITRM20130280A1 (it) 2014-11-11

Family

ID=48672714

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000280A ITRM20130280A1 (it) 2013-05-10 2013-05-10 Procedimento per la preparazione di eritrociti caricati con una o più sostanze di interesse farmaceutico.

Country Status (2)

Country Link
IT (1) ITRM20130280A1 (fr)
MA (1) MA38625B1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327710A (en) * 1980-06-18 1982-05-04 The United States Of America As Represented By The Secretary Of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
EP0882448A1 (fr) * 1997-05-05 1998-12-09 DIDECO S.p.A. Méthode d'encapsulation d'agents actifs biologiquement dans des erythrocytes et appareil
WO2011135429A1 (fr) * 2010-04-26 2011-11-03 Erydel S.P.A. Appareil et kit d'encapsulation d'au moins un composé à usage thérapeutique et/ou diagnostique dans des érythrocytes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327710A (en) * 1980-06-18 1982-05-04 The United States Of America As Represented By The Secretary Of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
EP0882448A1 (fr) * 1997-05-05 1998-12-09 DIDECO S.p.A. Méthode d'encapsulation d'agents actifs biologiquement dans des erythrocytes et appareil
WO2011135429A1 (fr) * 2010-04-26 2011-11-03 Erydel S.P.A. Appareil et kit d'encapsulation d'au moins un composé à usage thérapeutique et/ou diagnostique dans des érythrocytes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROPARS C ET AL: "RESEALED RED BLOOD CELLS AS A NEW BLOOD TRANSFUSION PRODUCT", BIBLIOTHECA HAEMATOLOGICA, BASEL, CH, no. 51, 1 January 1985 (1985-01-01), pages 82 - 91, XP002043887, ISSN: 0067-7957 *

Also Published As

Publication number Publication date
MA38625B1 (fr) 2018-04-30
MA38625A1 (fr) 2017-09-29

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