ITRM920027A1 - Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. - Google Patents

Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.

Info

Publication number
ITRM920027A1
ITRM920027A1 IT000027A ITRM920027A ITRM920027A1 IT RM920027 A1 ITRM920027 A1 IT RM920027A1 IT 000027 A IT000027 A IT 000027A IT RM920027 A ITRM920027 A IT RM920027A IT RM920027 A1 ITRM920027 A1 IT RM920027A1
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
antibacterial activity
acil
compositions containing
long chain
Prior art date
Application number
IT000027A
Other languages
English (en)
Inventor
Piero Foresta
Domenico Misiti
Mose Santaniello
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM920027A0 publication Critical patent/ITRM920027A0/it
Priority to ITRM920027A priority Critical patent/IT1254135B/it
Priority to CA002087085A priority patent/CA2087085C/en
Priority to ZA93162A priority patent/ZA93162B/xx
Priority to JP00476493A priority patent/JP3294653B2/ja
Priority to DE69305540T priority patent/DE69305540T2/de
Priority to EP93830009A priority patent/EP0552137B1/en
Priority to ES93830009T priority patent/ES2093395T3/es
Priority to DK93830009.2T priority patent/DK0552137T3/da
Priority to AT93830009T priority patent/ATE144492T1/de
Priority to KR1019930000522A priority patent/KR100251888B1/ko
Publication of ITRM920027A1 publication Critical patent/ITRM920027A1/it
Priority to US08/250,107 priority patent/US5498632A/en
Priority to US08/408,394 priority patent/US5498633A/en
Application granted granted Critical
Publication of IT1254135B publication Critical patent/IT1254135B/it
Priority to GR960402838T priority patent/GR3021479T3/el
Priority to HK98104924.6A priority patent/HK1005724B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITRM920027A 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. IT1254135B (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ITRM920027A IT1254135B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.
CA002087085A CA2087085C (en) 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
ZA93162A ZA93162B (en) 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity.
JP00476493A JP3294653B2 (ja) 1992-01-16 1993-01-14 アシルカルニチンエステル類および抗菌活性医薬組成物
ES93830009T ES2093395T3 (es) 1992-01-16 1993-01-15 Esteres de acil carnitinas con alcoholes alifaticos de cadena larga y composiciones farmaceuticas que los contienen con actividad antibacteriana.
EP93830009A EP0552137B1 (en) 1992-01-16 1993-01-15 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
DE69305540T DE69305540T2 (de) 1992-01-16 1993-01-15 Ester des Acyl-Carnitins mit langkettigen aliphatischen Alkoholen und diese enthaltende pharmazeutische Zusammensetzungen mit antibakterieller Wirkung
DK93830009.2T DK0552137T3 (da) 1992-01-16 1993-01-15 Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet
AT93830009T ATE144492T1 (de) 1992-01-16 1993-01-15 Ester des acyl-carnitins mit langkettigen aliphatischen alkoholen und diese enthaltende pharmazeutische zusammensetzungen mit antibakterieller wirkung
KR1019930000522A KR100251888B1 (ko) 1992-01-16 1993-01-16 긴 사슬의 지방족 알콜을 가진 아실카르니틴 에스테르와 항박테리아 활성을 지닌 그의 약제조성물
US08/250,107 US5498632A (en) 1992-01-16 1994-05-26 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
US08/408,394 US5498633A (en) 1992-01-16 1995-03-22 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
GR960402838T GR3021479T3 (en) 1992-01-16 1996-10-24 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
HK98104924.6A HK1005724B (en) 1992-01-16 1998-06-05 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920027A IT1254135B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.

Publications (3)

Publication Number Publication Date
ITRM920027A0 ITRM920027A0 (it) 1992-01-16
ITRM920027A1 true ITRM920027A1 (it) 1993-07-16
IT1254135B IT1254135B (it) 1995-09-08

Family

ID=11400572

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920027A IT1254135B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.

Country Status (12)

Country Link
US (2) US5498632A (it)
EP (1) EP0552137B1 (it)
JP (1) JP3294653B2 (it)
KR (1) KR100251888B1 (it)
AT (1) ATE144492T1 (it)
CA (1) CA2087085C (it)
DE (1) DE69305540T2 (it)
DK (1) DK0552137T3 (it)
ES (1) ES2093395T3 (it)
GR (1) GR3021479T3 (it)
IT (1) IT1254135B (it)
ZA (1) ZA93162B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
IT1274157B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
IT1274156B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
JPH08133971A (ja) * 1994-09-16 1996-05-28 Toyama Chem Co Ltd 抗ヘリコバクター剤
IT1283955B1 (it) * 1996-03-20 1998-05-07 Sigma Tau Ind Farmaceuti Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.
KR100513996B1 (ko) * 1996-11-21 2005-12-07 아지노모토 가부시키가이샤 연속발효에의한l-글루탐산의제조방법
US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
PL2286794T3 (pl) 2003-10-15 2016-10-31 Zastosowanie kationowych liposomów zawierających paklitaksel
WO2005036971A1 (en) * 2003-10-16 2005-04-28 Techcom Group, Llc Reduced digestible carbohydrate food having reduced blood glucose response
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
JP5700909B2 (ja) 2005-05-04 2015-04-15 メディゲーネ アクチエンゲゼルシャフトＭｅｄｉＧｅｎｅ ＡＧ パクリタキセルを含む陽イオン性リポソーム製剤を投与する方法
MX2008011978A (es) 2006-03-22 2009-04-22 Medigene Ag Tratamiento del cancer de seno negativo al triple receptor.
EP2394640A1 (en) 2010-05-21 2011-12-14 MediGene AG Improved liposomal formulations of lipophilic compounds
EP2575896A2 (en) 2010-05-26 2013-04-10 Erik Reimhult Magnetically responsive membrane structures
BR112014022847B1 (pt) 2012-03-16 2022-08-23 Merck Patent Gmbh Lipídios aminoácidos, composição vesicular, e kit
NZ631034A (en) 2012-03-16 2016-06-24 Merck Patent Gmbh Targeting aminoacid lipids
US11785966B2 (en) * 2019-03-06 2023-10-17 Anipha Technologies Pty Ltd Use of gamma-quaternary ammonium butyrate compound in preparation of an animal feed additive

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588443A5 (it) * 1974-09-25 1977-06-15 Lonza Ag
CH596147A5 (it) * 1974-09-25 1978-02-28 Lonza Ag
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1170861B (it) * 1981-03-31 1987-06-03 Sigma Tau Ind Farmaceuti Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1191945B (it) * 1986-06-04 1988-03-31 Avantgarde Spa N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1235494B (it) * 1987-12-02 1992-09-04 Avantgarde Spa N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.

Also Published As

Publication number Publication date
DE69305540T2 (de) 1997-03-06
ZA93162B (en) 1993-09-30
US5498633A (en) 1996-03-12
JP3294653B2 (ja) 2002-06-24
CA2087085C (en) 2003-12-16
ES2093395T3 (es) 1996-12-16
KR930016391A (ko) 1993-08-26
EP0552137A3 (en) 1993-10-20
ITRM920027A0 (it) 1992-01-16
DK0552137T3 (da) 1996-11-18
HK1005724A1 (en) 1999-01-22
JPH05339218A (ja) 1993-12-21
EP0552137A2 (en) 1993-07-21
US5498632A (en) 1996-03-12
ATE144492T1 (de) 1996-11-15
DE69305540D1 (de) 1996-11-28
KR100251888B1 (ko) 2000-05-01
IT1254135B (it) 1995-09-08
EP0552137B1 (en) 1996-10-23
CA2087085A1 (en) 1993-07-17
GR3021479T3 (en) 1997-01-31

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