ITRM920138A0 - Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono. - Google Patents

Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.

Info

Publication number
ITRM920138A0
ITRM920138A0 IT92RM138A ITRM920138A ITRM920138A0 IT RM920138 A0 ITRM920138 A0 IT RM920138A0 IT 92RM138 A IT92RM138 A IT 92RM138A IT RM920138 A ITRM920138 A IT RM920138A IT RM920138 A0 ITRM920138 A0 IT RM920138A0
Authority
IT
Italy
Prior art keywords
carnitine
acil
gastro
esters
selective
Prior art date
Application number
IT92RM138A
Other languages
English (en)
Inventor
Mose Santaniello
Maria Ornella Tinti
Domenico Misiti
Nazareno Scafetta
Maria Antonietta Stasi
Loredana Vesci
Nerina Corsico
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM920138A0 publication Critical patent/ITRM920138A0/it
Priority to ITRM920138A priority Critical patent/IT1258370B/it
Priority to DE69313325T priority patent/DE69313325T2/de
Priority to EP93830083A priority patent/EP0559625B1/en
Priority to ES93830083T priority patent/ES2106998T3/es
Priority to AT93830083T priority patent/ATE157348T1/de
Priority to DK93830083.7T priority patent/DK0559625T3/da
Publication of ITRM920138A1 publication Critical patent/ITRM920138A1/it
Application granted granted Critical
Publication of IT1258370B publication Critical patent/IT1258370B/it
Priority to GR970402734T priority patent/GR3025093T3/el
Priority to HK98105619.3A priority patent/HK1006368B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ITRM920138A 1992-03-02 1992-03-02 Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono. IT1258370B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITRM920138A IT1258370B (it) 1992-03-02 1992-03-02 Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.
AT93830083T ATE157348T1 (de) 1992-03-02 1993-03-01 Ester von l-carnitin und acyl-l-carnitin, mit entspannender wirkung, selektiv auf den gastrointestinaltrakt und sie enthaltende pharmazeutische zusammensetzungen
EP93830083A EP0559625B1 (en) 1992-03-02 1993-03-01 Esters of L-carnitine and acyl L-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same
ES93830083T ES2106998T3 (es) 1992-03-02 1993-03-01 Esteres de l-carnitina y acil-l-carnitina dotados de actividad relajante de los musculos, selectiva en el tracto gastro-intestinal y composiciones farmaceuticas que los contienen.
DE69313325T DE69313325T2 (de) 1992-03-02 1993-03-01 Ester von L-Carnitin und Acyl-L-Carnitin, mit entspannender Wirkung, selektiv auf den Gastrointestinaltrakt und sie enthaltende pharmazeutische Zusammensetzungen
DK93830083.7T DK0559625T3 (da) 1992-03-02 1993-03-01 Estere af L-carnitin og acyl-carnitin med muskelafslappende virkning, der er selektive på mave-tarm-kanalen, og farmaceutiske præparater indeholdende disse
GR970402734T GR3025093T3 (en) 1992-03-02 1997-10-20 Esters of L-carnitine and acyl L-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same
HK98105619.3A HK1006368B (en) 1992-03-02 1998-06-18 Esters of l-carnitine and acyl l-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920138A IT1258370B (it) 1992-03-02 1992-03-02 Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.

Publications (3)

Publication Number Publication Date
ITRM920138A0 true ITRM920138A0 (it) 1992-03-02
ITRM920138A1 ITRM920138A1 (it) 1993-09-02
IT1258370B IT1258370B (it) 1996-02-26

Family

ID=11400749

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920138A IT1258370B (it) 1992-03-02 1992-03-02 Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.

Country Status (7)

Country Link
EP (1) EP0559625B1 (it)
AT (1) ATE157348T1 (it)
DE (1) DE69313325T2 (it)
DK (1) DK0559625T3 (it)
ES (1) ES2106998T3 (it)
GR (1) GR3025093T3 (it)
IT (1) IT1258370B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607691A (en) * 1992-06-12 1997-03-04 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
IT1261231B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
ATE200479T1 (de) * 1996-05-31 2001-04-15 Sigma Tau Ind Farmaceuti Stabile nichthygroskopische salze von l(- )carnitin und alkanoyl-l(-)carnitinen, verfahren zu ihrer herstellung und feste, oral verabreichbare zusammensetzungen,die sie enthalten
IT1284661B1 (it) * 1996-06-06 1998-05-21 Sigma Tau Ind Farmaceuti Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
IT1299172B1 (it) * 1998-05-06 2000-02-29 Sigma Tau Ind Farmaceuti Esteri perfluorurati di alcanoil l-carnitine utilizzabili quali lipidi cationici per l'immissione intracellulare di composti
IT1306129B1 (it) * 1999-04-13 2001-05-30 Sigma Tau Ind Farmaceuti Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
AU2007214359B2 (en) * 1999-04-13 2009-02-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Esters of L-carnitine or alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
JP2020522534A (ja) * 2017-06-06 2020-07-30 ウェイン ステート ユニバーシティＷａｙｎｅ Ｓｔａｔｅ Ｕｎｉｖｅｒｓｉｔｙ カルニチン由来材料に関する方法および組成物
AU2019432401B9 (en) * 2019-03-06 2023-09-28 Anipha Technologies Pty Ltd USE OF γ-QUATERNARY AMMONIUM BUTYRATE COMPOUND IN PREPARATION OF ANIMAL FEED ADDITIVE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1209564B (it) * 1984-06-29 1989-08-30 Magis Farmaceutici Derivati della l-carnitina o di l-acil carnitina.
IT1254136B (it) * 1992-01-16 1995-09-08 Sigma Tau Ind Farmaceuti Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.

Also Published As

Publication number Publication date
ITRM920138A1 (it) 1993-09-02
EP0559625A2 (en) 1993-09-08
EP0559625A3 (en) 1993-12-01
IT1258370B (it) 1996-02-26
DE69313325D1 (de) 1997-10-02
ATE157348T1 (de) 1997-09-15
DE69313325T2 (de) 1998-01-29
HK1006368A1 (en) 1999-02-26
ES2106998T3 (es) 1997-11-16
GR3025093T3 (en) 1998-01-30
DK0559625T3 (da) 1997-12-29
EP0559625B1 (en) 1997-08-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970123