ITRM940073A0 - Muteine della ribonucleasi pancreatica e loro usi. - Google Patents

Muteine della ribonucleasi pancreatica e loro usi.

Info

Publication number
ITRM940073A0
ITRM940073A0 ITRM940073A ITRM940073A ITRM940073A0 IT RM940073 A0 ITRM940073 A0 IT RM940073A0 IT RM940073 A ITRM940073 A IT RM940073A IT RM940073 A ITRM940073 A IT RM940073A IT RM940073 A0 ITRM940073 A0 IT RM940073A0
Authority
IT
Italy
Prior art keywords
ribonucleasis
muteins
pancreatic
ribonucleasis muteins
pancreatic ribonucleasis
Prior art date
Application number
ITRM940073A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ITRM940073A priority Critical patent/IT1271864B/it
Publication of ITRM940073A0 publication Critical patent/ITRM940073A0/it
Priority to ES95830039T priority patent/ES2186709T3/es
Priority to AT95830039T priority patent/ATE227771T1/de
Priority to DE69528784T priority patent/DE69528784T2/de
Priority to EP95830039A priority patent/EP0668349B1/en
Publication of ITRM940073A1 publication Critical patent/ITRM940073A1/it
Application granted granted Critical
Publication of IT1271864B publication Critical patent/IT1271864B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6815Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ITRM940073A 1994-02-16 1994-02-16 Muteine della ribonucleasi pancreatica e loro usi. IT1271864B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITRM940073A IT1271864B (it) 1994-02-16 1994-02-16 Muteine della ribonucleasi pancreatica e loro usi.
ES95830039T ES2186709T3 (es) 1994-02-16 1995-02-15 Muteinas de ribonucleasa pancreatica y sus usos.
AT95830039T ATE227771T1 (de) 1994-02-16 1995-02-15 Pankreatische ribonuclease mutante und ihre verwendung
DE69528784T DE69528784T2 (de) 1994-02-16 1995-02-15 Pankreatische ribonuclease Mutante und ihre Verwendung
EP95830039A EP0668349B1 (en) 1994-02-16 1995-02-15 Muteins of pancreatic ribonuclease and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM940073A IT1271864B (it) 1994-02-16 1994-02-16 Muteine della ribonucleasi pancreatica e loro usi.

Publications (3)

Publication Number Publication Date
ITRM940073A0 true ITRM940073A0 (it) 1994-02-16
ITRM940073A1 ITRM940073A1 (it) 1995-08-16
IT1271864B IT1271864B (it) 1997-06-09

Family

ID=11402242

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM940073A IT1271864B (it) 1994-02-16 1994-02-16 Muteine della ribonucleasi pancreatica e loro usi.

Country Status (5)

Country Link
EP (1) EP0668349B1 (it)
AT (1) ATE227771T1 (it)
DE (1) DE69528784T2 (it)
ES (1) ES2186709T3 (it)
IT (1) IT1271864B (it)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389537A (en) * 1994-01-21 1995-02-14 Wisconsin Alumni Research Foundation Nuclease having altered specificity

Also Published As

Publication number Publication date
DE69528784D1 (de) 2002-12-19
EP0668349B1 (en) 2002-11-13
EP0668349A3 (en) 1996-08-28
EP0668349A2 (en) 1995-08-23
ITRM940073A1 (it) 1995-08-16
ATE227771T1 (de) 2002-11-15
IT1271864B (it) 1997-06-09
ES2186709T3 (es) 2003-05-16
DE69528784T2 (de) 2003-07-17

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Legal Events

Date Code Title Description
0001 Granted