JO2082B1 - The formed granules of clavulinite and excipients - Google Patents
The formed granules of clavulinite and excipientsInfo
- Publication number
- JO2082B1 JO2082B1 JO19982082A JOP19982082A JO2082B1 JO 2082 B1 JO2082 B1 JO 2082B1 JO 19982082 A JO19982082 A JO 19982082A JO P19982082 A JOP19982082 A JO P19982082A JO 2082 B1 JO2082 B1 JO 2082B1
- Authority
- JO
- Jordan
- Prior art keywords
- granules
- clavulanate
- excipients
- employing
- prepare
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 2
- 229940090805 clavulanate Drugs 0.000 title abstract 2
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- 239000008187 granular material Substances 0.000 title abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203576 | 1997-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2082B1 true JO2082B1 (en) | 2000-05-21 |
Family
ID=8228930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19982082A JO2082B1 (en) | 1997-11-17 | 1998-11-17 | The formed granules of clavulinite and excipients |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0973520A1 (fr) |
| JP (1) | JP2001516365A (fr) |
| CN (1) | CN1242705A (fr) |
| AU (1) | AU1337999A (fr) |
| BR (1) | BR9806280A (fr) |
| CA (1) | CA2272402A1 (fr) |
| CO (1) | CO4980893A1 (fr) |
| JO (1) | JO2082B1 (fr) |
| NO (1) | NO993467L (fr) |
| PL (1) | PL334517A1 (fr) |
| TR (1) | TR199901584T1 (fr) |
| WO (1) | WO1999025343A1 (fr) |
| ZA (1) | ZA9810499B (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294199B1 (en) | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
| US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
| US7250176B1 (en) | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
| US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
| EP1330236A2 (fr) | 2000-10-12 | 2003-07-30 | Beecham Pharmaceuticals (Pte) Limited | Nouvelle formulation |
| GB0031267D0 (en) * | 2000-12-21 | 2001-01-31 | Smithkline Beecham Plc | Novel compositions |
| AT412344B (de) * | 2001-04-12 | 2005-01-25 | Sandoz Ag | Hydrophobisierte teilchen von k-clavulanat |
| AT413983B (de) * | 2001-04-12 | 2006-08-15 | Sandoz Ag | K-clavulanat in der form eines granulates |
| AU2004234176B2 (en) * | 2003-05-02 | 2010-05-13 | Globopharm Pharmazeutische Produktions- Und Handelsgesellschaft M.B.H. | Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts |
| US8293272B2 (en) * | 2003-05-02 | 2012-10-23 | Globopharm Pharmazeutische Produktions-Und Handelsgesellschaft M.B.H. | Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts |
| FI20080352A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi |
| US8951562B2 (en) | 2006-11-10 | 2015-02-10 | Atacama Labs Oy | Method and apparatus or dry granulation |
| FI20080351A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi |
| FI20080346A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi lisäaineita sisältävän tabletin valmistamiseksi |
| FI20080353A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi erittäin korkean lääkepitoisuuden tabletin valmistamiseksi |
| FI20070521A7 (fi) | 2006-11-10 | 2008-05-11 | Atacama Labs Oy | Rakeita, tabletteja ja rakeistusmenetelmä |
| FI20080355A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi metforminia käsittävien tablettien valmistamiseksi |
| CA2723409C (fr) | 2008-05-09 | 2016-11-08 | Atacama Labs Oy | Procede et appareil de granulation par voie seche |
| CN104582692A (zh) * | 2012-08-28 | 2015-04-29 | 中化帝斯曼制药有限公司荷兰公司 | 包含抗生素和β-内酰胺酶抑制剂的组合物,其中抗生素和β-内酰胺酶抑制剂中的至少一种是迷你片剂的形式 |
| JP2014062064A (ja) * | 2012-09-21 | 2014-04-10 | Ohara Yakuhin Kogyo Kk | バルサルタン含有錠剤の製造方法 |
| JP6141472B2 (ja) * | 2016-03-02 | 2017-06-07 | 大原薬品工業株式会社 | バルサルタン含有錠剤の製造方法 |
| KR20250026366A (ko) * | 2017-07-05 | 2025-02-25 | 노파르티스 아게 | 신규한 약학적 조성물 |
| CN110051637A (zh) * | 2019-05-21 | 2019-07-26 | 葵花药业集团北京药物研究院有限公司 | 阿莫西林克拉维酸钾制剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2251250C3 (de) * | 1972-10-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten |
| NZ187013A (en) * | 1977-04-27 | 1985-04-30 | Beecham Group Ltd | 9-amino-9-deoxy-clavulanic acid derivatives and pharmaceutical compositions |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| DE3887179T2 (de) * | 1987-03-02 | 1994-06-16 | Brocades Pharma Bv | Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. |
| IL109770A0 (en) * | 1993-05-29 | 1994-11-28 | Smithkline Beecham Corp | Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby |
-
1998
- 1998-11-09 TR TR1999/01584T patent/TR199901584T1/xx unknown
- 1998-11-09 AU AU13379/99A patent/AU1337999A/en not_active Abandoned
- 1998-11-09 PL PL98334517A patent/PL334517A1/xx unknown
- 1998-11-09 CN CN98801549A patent/CN1242705A/zh active Pending
- 1998-11-09 CA CA002272402A patent/CA2272402A1/fr not_active Abandoned
- 1998-11-09 WO PCT/EP1998/007225 patent/WO1999025343A1/fr not_active Ceased
- 1998-11-09 EP EP98956907A patent/EP0973520A1/fr not_active Withdrawn
- 1998-11-09 JP JP52751299A patent/JP2001516365A/ja active Pending
- 1998-11-09 BR BR9806280-8A patent/BR9806280A/pt not_active Application Discontinuation
- 1998-11-17 JO JO19982082A patent/JO2082B1/en active
- 1998-11-17 ZA ZA9810499A patent/ZA9810499B/xx unknown
- 1998-11-17 CO CO98067517A patent/CO4980893A1/es unknown
-
1999
- 1999-07-14 NO NO993467A patent/NO993467L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1337999A (en) | 1999-06-07 |
| ZA9810499B (en) | 1999-05-24 |
| TR199901584T1 (xx) | 2000-01-21 |
| CO4980893A1 (es) | 2000-11-27 |
| PL334517A1 (en) | 2000-02-28 |
| WO1999025343A1 (fr) | 1999-05-27 |
| JP2001516365A (ja) | 2001-09-25 |
| EP0973520A1 (fr) | 2000-01-26 |
| NO993467D0 (no) | 1999-07-14 |
| BR9806280A (pt) | 2000-02-15 |
| CN1242705A (zh) | 2000-01-26 |
| CA2272402A1 (fr) | 1999-05-27 |
| NO993467L (no) | 1999-07-14 |
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