PL2493930T3 - Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania - Google Patents

Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania

Info

Publication number
PL2493930T3
PL2493930T3 PL10826929T PL10826929T PL2493930T3 PL 2493930 T3 PL2493930 T3 PL 2493930T3 PL 10826929 T PL10826929 T PL 10826929T PL 10826929 T PL10826929 T PL 10826929T PL 2493930 T3 PL2493930 T3 PL 2493930T3
Authority
PL
Poland
Prior art keywords
fraktalkine
antibodies
improved anti
anti human
human
Prior art date
Application number
PL10826929T
Other languages
English (en)
Inventor
Miyuki Nishimura
Yoshimasa Sakamoto
Tetsu Kawano
Toshio Imai
Original Assignee
Eisai R&D Management Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2493930(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai R&D Management Co., Ltd. filed Critical Eisai R&D Management Co., Ltd.
Publication of PL2493930T3 publication Critical patent/PL2493930T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL10826929T 2009-10-30 2010-10-28 Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania PL2493930T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25652109P 2009-10-30 2009-10-30
PCT/JP2010/069653 WO2011052799A1 (en) 2009-10-30 2010-10-28 Compositions and methods for treating inflammatory disorders
EP10826929.1A EP2493930B1 (en) 2009-10-30 2010-10-28 Improved anti human Fraktalkine antibodies and uses thereof

Publications (1)

Publication Number Publication Date
PL2493930T3 true PL2493930T3 (pl) 2019-03-29

Family

ID=43922220

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10826929T PL2493930T3 (pl) 2009-10-30 2010-10-28 Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania

Country Status (33)

Country Link
US (1) US8932592B2 (pl)
EP (1) EP2493930B1 (pl)
JP (2) JP5631991B2 (pl)
KR (2) KR102099596B1 (pl)
CN (1) CN102597003B (pl)
AR (2) AR078796A1 (pl)
AU (1) AU2010312408B2 (pl)
BR (1) BR112012010266A2 (pl)
CA (1) CA2778895C (pl)
CL (2) CL2012001143A1 (pl)
CY (1) CY1121167T1 (pl)
DK (1) DK2493930T3 (pl)
ES (1) ES2698389T3 (pl)
HR (1) HRP20181973T1 (pl)
HU (1) HUE041952T2 (pl)
IL (1) IL219470A (pl)
JO (1) JO3437B1 (pl)
LT (1) LT2493930T (pl)
MX (1) MX2012005052A (pl)
MY (1) MY158481A (pl)
NZ (1) NZ599779A (pl)
PE (1) PE20121645A1 (pl)
PH (1) PH12012500828A1 (pl)
PL (1) PL2493930T3 (pl)
PT (1) PT2493930T (pl)
RS (1) RS58142B1 (pl)
RU (1) RU2569109C2 (pl)
SI (1) SI2493930T1 (pl)
SM (1) SMT201800637T1 (pl)
TW (1) TWI414308B (pl)
UA (1) UA105073C2 (pl)
WO (1) WO2011052799A1 (pl)
ZA (1) ZA201203002B (pl)

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US9415118B2 (en) * 2013-03-13 2016-08-16 Novartis Ag Antibody drug conjugates
ES2826566T3 (es) 2014-11-21 2021-05-18 Bristol Myers Squibb Co Anticuerpos que comprenden regiones constantes pesadas modificadas
JP6805142B2 (ja) 2014-11-21 2020-12-23 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Cd73に対する抗体およびその使用
EP3159007A1 (en) 2015-10-19 2017-04-26 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating rheumatoid arthritis
JP2017154975A (ja) * 2016-02-29 2017-09-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
JP2018070473A (ja) * 2016-10-26 2018-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 関節リウマチを治療するための医薬組成物
JP2018177701A (ja) * 2017-04-14 2018-11-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
US20220196674A1 (en) * 2019-04-17 2022-06-23 Abdolamir Landi Treatment of autoimmune liver disease
CN113710272A (zh) * 2019-04-23 2021-11-26 卫材R&D管理有限公司 用于治疗类风湿性关节炎的生物标记物
CA3161271A1 (en) * 2019-12-09 2021-06-17 Alexion Pharmaceuticals, Inc. Anti-c5 antibody for the treatment of neuromyelitis optica spectrum disorder
CN113087795B (zh) * 2019-12-23 2025-06-10 上海普铭生物科技有限公司 针对趋化因子cx3cl1的抗体及其应用
WO2022092183A1 (ja) 2020-10-30 2022-05-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 医薬組成物
CN121537534B (zh) * 2026-01-22 2026-04-07 华中科技大学同济医学院附属协和医院 靶向cx3cl1的嵌合抗原受体-巨噬细胞及在gjb2突变相关遗传性耳聋治疗中的应用

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Also Published As

Publication number Publication date
AU2010312408A1 (en) 2012-06-21
KR101627605B1 (ko) 2016-06-07
SMT201800637T1 (it) 2019-01-11
EP2493930A4 (en) 2013-12-04
KR102099596B1 (ko) 2020-04-10
SI2493930T1 (sl) 2018-12-31
US8932592B2 (en) 2015-01-13
IL219470A (en) 2017-10-31
MX2012005052A (es) 2012-05-29
ES2698389T3 (es) 2019-02-04
RU2012122203A (ru) 2013-12-10
CA2778895C (en) 2018-08-07
CA2778895A1 (en) 2011-05-05
EP2493930A1 (en) 2012-09-05
WO2011052799A1 (en) 2011-05-05
MY158481A (en) 2016-10-14
CN102597003A (zh) 2012-07-18
PT2493930T (pt) 2018-11-29
RU2569109C2 (ru) 2015-11-20
CY1121167T1 (el) 2020-05-29
HUE041952T2 (hu) 2019-06-28
RS58142B1 (sr) 2019-02-28
AU2010312408B2 (en) 2015-07-09
ZA201203002B (en) 2013-06-26
CL2015000114A1 (es) 2015-04-10
CL2012001143A1 (es) 2012-10-05
KR20160066055A (ko) 2016-06-09
UA105073C2 (uk) 2014-04-10
JP2015027304A (ja) 2015-02-12
AR109533A2 (es) 2018-12-19
LT2493930T (lt) 2019-01-10
US20120213799A1 (en) 2012-08-23
NZ599779A (en) 2014-03-28
JO3437B1 (ar) 2019-10-20
BR112012010266A2 (pt) 2016-12-06
PE20121645A1 (es) 2012-12-06
KR20120104560A (ko) 2012-09-21
IL219470A0 (en) 2012-06-28
JP5631991B2 (ja) 2014-11-26
JP2013509158A (ja) 2013-03-14
PH12012500828A1 (en) 2013-01-07
EP2493930B1 (en) 2018-09-19
AR078796A1 (es) 2011-12-07
DK2493930T3 (en) 2018-12-17
HRP20181973T1 (hr) 2019-01-25
TW201127401A (en) 2011-08-16
CN102597003B (zh) 2016-03-23
TWI414308B (zh) 2013-11-11

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