PL2493930T3 - Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania - Google Patents

Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania

Info

Publication number
PL2493930T3
PL2493930T3 PL10826929T PL10826929T PL2493930T3 PL 2493930 T3 PL2493930 T3 PL 2493930T3 PL 10826929 T PL10826929 T PL 10826929T PL 10826929 T PL10826929 T PL 10826929T PL 2493930 T3 PL2493930 T3 PL 2493930T3
Authority
PL
Poland
Prior art keywords
fraktalkine
antibodies
improved anti
anti human
human
Prior art date
Application number
PL10826929T
Other languages
English (en)
Inventor
Miyuki Nishimura
Yoshimasa Sakamoto
Tetsu Kawano
Toshio Imai
Original Assignee
Eisai R&D Management Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2493930(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai R&D Management Co., Ltd. filed Critical Eisai R&D Management Co., Ltd.
Publication of PL2493930T3 publication Critical patent/PL2493930T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL10826929T 2009-10-30 2010-10-28 Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania PL2493930T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25652109P 2009-10-30 2009-10-30
PCT/JP2010/069653 WO2011052799A1 (en) 2009-10-30 2010-10-28 Compositions and methods for treating inflammatory disorders
EP10826929.1A EP2493930B1 (en) 2009-10-30 2010-10-28 Improved anti human Fraktalkine antibodies and uses thereof

Publications (1)

Publication Number Publication Date
PL2493930T3 true PL2493930T3 (pl) 2019-03-29

Family

ID=43922220

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10826929T PL2493930T3 (pl) 2009-10-30 2010-10-28 Udoskonalone przeciwciała przeciwko ludzkiej fraktalkinie i ich zastosowania

Country Status (33)

Country Link
US (1) US8932592B2 (pl)
EP (1) EP2493930B1 (pl)
JP (2) JP5631991B2 (pl)
KR (2) KR101627605B1 (pl)
CN (1) CN102597003B (pl)
AR (2) AR078796A1 (pl)
AU (1) AU2010312408B2 (pl)
BR (1) BR112012010266A2 (pl)
CA (1) CA2778895C (pl)
CL (2) CL2012001143A1 (pl)
CY (1) CY1121167T1 (pl)
DK (1) DK2493930T3 (pl)
ES (1) ES2698389T3 (pl)
HR (1) HRP20181973T1 (pl)
HU (1) HUE041952T2 (pl)
IL (1) IL219470A (pl)
JO (1) JO3437B1 (pl)
LT (1) LT2493930T (pl)
MX (1) MX2012005052A (pl)
MY (1) MY158481A (pl)
NZ (1) NZ599779A (pl)
PE (1) PE20121645A1 (pl)
PH (1) PH12012500828A1 (pl)
PL (1) PL2493930T3 (pl)
PT (1) PT2493930T (pl)
RS (1) RS58142B1 (pl)
RU (1) RU2569109C2 (pl)
SI (1) SI2493930T1 (pl)
SM (1) SMT201800637T1 (pl)
TW (1) TWI414308B (pl)
UA (1) UA105073C2 (pl)
WO (1) WO2011052799A1 (pl)
ZA (1) ZA201203002B (pl)

Families Citing this family (12)

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US9415118B2 (en) * 2013-03-13 2016-08-16 Novartis Ag Antibody drug conjugates
KR102569813B1 (ko) 2014-11-21 2023-08-24 브리스톨-마이어스 스큅 컴퍼니 Cd73에 대항한 항체 및 그의 용도
CN113929770A (zh) 2014-11-21 2022-01-14 百时美施贵宝公司 包含修饰的重链恒定区的抗体
EP3159007A1 (en) 2015-10-19 2017-04-26 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating rheumatoid arthritis
JP2017154975A (ja) * 2016-02-29 2017-09-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
JP2018070473A (ja) * 2016-10-26 2018-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 関節リウマチを治療するための医薬組成物
JP2018177701A (ja) * 2017-04-14 2018-11-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 クローン病を治療するための医薬組成物
WO2020214166A1 (en) * 2019-04-17 2020-10-22 The Governors Of The University Of Alberta Treatment of autoimmune liver disease
JP7550142B2 (ja) * 2019-04-23 2024-09-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 関節リウマチ治療のためのバイオマーカー
EP4073110A1 (en) * 2019-12-09 2022-10-19 Alexion Pharmaceuticals, Inc. Anti-c5 antibody for the treatment of neuromyelitis optica spectrum disorder
CN113087795B (zh) * 2019-12-23 2025-06-10 上海普铭生物科技有限公司 针对趋化因子cx3cl1的抗体及其应用
WO2022092183A1 (ja) 2020-10-30 2022-05-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 医薬組成物

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US6291158B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for tapping the immunological repertoire
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
US6180377B1 (en) 1993-06-16 2001-01-30 Celltech Therapeutics Limited Humanized antibodies
US6096312A (en) 1995-06-30 2000-08-01 Mochida Pharmaceutical Co., Ltd. Agent for suppressing a reduction of CD4+ lymphocytes
CN1196733A (zh) * 1995-06-30 1998-10-21 持田制药株式会社 抗Fas配体抗体和利用抗Fas配体抗体的测定方法
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JPH11503030A (ja) 1996-01-24 1999-03-23 シェーリング コーポレイション 哺乳動物cx3cケモカイン遺伝子
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AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
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Also Published As

Publication number Publication date
RU2012122203A (ru) 2013-12-10
US20120213799A1 (en) 2012-08-23
CN102597003A (zh) 2012-07-18
EP2493930A4 (en) 2013-12-04
DK2493930T3 (en) 2018-12-17
WO2011052799A1 (en) 2011-05-05
PH12012500828A1 (en) 2013-01-07
LT2493930T (lt) 2019-01-10
JP2013509158A (ja) 2013-03-14
BR112012010266A2 (pt) 2016-12-06
JO3437B1 (ar) 2019-10-20
CL2012001143A1 (es) 2012-10-05
IL219470A0 (en) 2012-06-28
AR078796A1 (es) 2011-12-07
SI2493930T1 (sl) 2018-12-31
KR20120104560A (ko) 2012-09-21
IL219470A (en) 2017-10-31
TW201127401A (en) 2011-08-16
RU2569109C2 (ru) 2015-11-20
CY1121167T1 (el) 2020-05-29
ES2698389T3 (es) 2019-02-04
HUE041952T2 (hu) 2019-06-28
JP5631991B2 (ja) 2014-11-26
CN102597003B (zh) 2016-03-23
AR109533A2 (es) 2018-12-19
PT2493930T (pt) 2018-11-29
HRP20181973T1 (hr) 2019-01-25
TWI414308B (zh) 2013-11-11
KR101627605B1 (ko) 2016-06-07
KR20160066055A (ko) 2016-06-09
AU2010312408A1 (en) 2012-06-21
CL2015000114A1 (es) 2015-04-10
ZA201203002B (en) 2013-06-26
NZ599779A (en) 2014-03-28
MY158481A (en) 2016-10-14
US8932592B2 (en) 2015-01-13
SMT201800637T1 (it) 2019-01-11
EP2493930A1 (en) 2012-09-05
RS58142B1 (sr) 2019-02-28
AU2010312408B2 (en) 2015-07-09
JP2015027304A (ja) 2015-02-12
EP2493930B1 (en) 2018-09-19
CA2778895C (en) 2018-08-07
KR102099596B1 (ko) 2020-04-10
CA2778895A1 (en) 2011-05-05
PE20121645A1 (es) 2012-12-06
MX2012005052A (es) 2012-05-29
UA105073C2 (uk) 2014-04-10

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