JO3680B1 - تركيبات صيدلانية موضعية - Google Patents
تركيبات صيدلانية موضعيةInfo
- Publication number
- JO3680B1 JO3680B1 JOP/2016/0097A JOP20160097A JO3680B1 JO 3680 B1 JO3680 B1 JO 3680B1 JO P20160097 A JOP20160097 A JO P20160097A JO 3680 B1 JO3680 B1 JO 3680B1
- Authority
- JO
- Jordan
- Prior art keywords
- topical pharmaceutical
- skin
- pharmaceutical compositions
- patient
- relates
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
يتعلق الاختراع الحالي بتركيبات مستحلبة صيدلانية موضعية تتضمن كمية فعالة علاجياً من 3، 5- ثاني هيدروكسي-4- أيزوبروبيل-ترانس- ستيلبين أو ملح مقبول صيدلانيا منه، طور زيتي، طور مائي، منشط للسطح، ومضاد للأكسدة، وفيها التركيب المستحلب عبارة عن مستحلب متجانس أو نشط والذي يذاب في طور الزيت. ويتعلق الاختراع أيضاً بطرق لعلاج حالات جلدية أو اضطراب الجلد في مريض بإعطاء التركيبات الحالية إلى جلد المريض
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562165097P | 2015-05-21 | 2015-05-21 | |
| US201662324450P | 2016-04-19 | 2016-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO3680B1 true JO3680B1 (ar) | 2020-08-27 |
Family
ID=56081527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2016/0097A JO3680B1 (ar) | 2015-05-21 | 2016-05-19 | تركيبات صيدلانية موضعية |
Country Status (35)
| Country | Link |
|---|---|
| US (5) | US10195160B2 (ar) |
| EP (2) | EP3297605B1 (ar) |
| JP (4) | JP6863904B2 (ar) |
| KR (2) | KR20240090730A (ar) |
| CN (2) | CN107666902B (ar) |
| AU (2) | AU2016263161B2 (ar) |
| BR (1) | BR112017024934A8 (ar) |
| CA (1) | CA2986251A1 (ar) |
| CL (1) | CL2017002939A1 (ar) |
| CO (1) | CO2017011795A2 (ar) |
| CR (1) | CR20170528A (ar) |
| CY (1) | CY1125318T1 (ar) |
| DK (1) | DK3297605T3 (ar) |
| DO (1) | DOP2017000270A (ar) |
| EA (1) | EA038624B1 (ar) |
| ES (1) | ES2914112T3 (ar) |
| HR (1) | HRP20220670T1 (ar) |
| HU (1) | HUE059066T2 (ar) |
| IL (3) | IL282304B2 (ar) |
| JO (1) | JO3680B1 (ar) |
| LT (1) | LT3297605T (ar) |
| MX (2) | MX377629B (ar) |
| PE (1) | PE20180038A1 (ar) |
| PH (1) | PH12017502092A1 (ar) |
| PL (1) | PL3297605T3 (ar) |
| PT (1) | PT3297605T (ar) |
| RS (1) | RS63402B1 (ar) |
| SG (1) | SG11201708666RA (ar) |
| SI (1) | SI3297605T1 (ar) |
| SM (1) | SMT202200224T1 (ar) |
| TW (1) | TWI705831B (ar) |
| UA (1) | UA125500C2 (ar) |
| UY (1) | UY36682A (ar) |
| WO (1) | WO2016185428A1 (ar) |
| ZA (1) | ZA202007965B (ar) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3297605T1 (sl) * | 2015-05-21 | 2022-08-31 | Dermavant Sciences GmbH | Topikalni farmacevtski sestavki |
| US11617724B2 (en) * | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| WO2019094934A1 (en) | 2017-11-10 | 2019-05-16 | Dermavant Sciences GmbH | Process for preparing tapinarof |
| CN109085257B (zh) * | 2018-07-05 | 2021-04-06 | 中央民族大学 | 一种同时定量检测小鼠血浆中黄芪甲苷-iv、环黄芪醇的方法 |
| MX368750B (es) * | 2018-08-31 | 2019-10-15 | Cell Therapy And Tech S A De C V | Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. |
| US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
| JP6898622B2 (ja) * | 2019-01-30 | 2021-07-07 | 学校法人神奈川大学 | 皮膚又は粘膜の外用剤及びその製造方法、並びに皮膚又は粘膜の外用剤の基剤 |
| KR20230110821A (ko) * | 2019-04-17 | 2023-07-25 | 아조라 테라퓨틱스 인코포레이티드 | 염증성 피부 질환을 치료하기 위한 국소 조성물 및방법 |
| JP7734587B2 (ja) * | 2019-05-15 | 2025-09-05 | レオ ファーマ アクティーゼルスカブ | 皮膚エリテマトーデスの治療 |
| US20200383887A1 (en) * | 2019-06-04 | 2020-12-10 | L'oreal | Oxygenate skin treatment system |
| WO2020264071A1 (en) | 2019-06-26 | 2020-12-30 | Locus Oil Ip Company, Llc | Multi-functional compositions comprising concentrated acids for enhanced oil and gas recovery |
| JP2022541605A (ja) * | 2019-07-24 | 2022-09-26 | ソル - ゲル テクノロジーズ リミテッド | 局所タピナロフ-egfr阻害剤組成物による皮膚障害の治療 |
| WO2021059281A1 (en) * | 2019-09-26 | 2021-04-01 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with topical combination compositions comprising tapinarof and an additional ahr activator |
| US20220387349A1 (en) * | 2019-09-26 | 2022-12-08 | Sol-Gel Technologies Ltd | Treatment of cutaneous adverse effects caused by oncological therapy with topical tapinarof compositions |
| CA3160126A1 (en) * | 2019-11-06 | 2021-05-14 | Sol-Gel Technologies Ltd. | Method of treating palmoplantar keratoderma |
| US20230000786A1 (en) * | 2019-11-24 | 2023-01-05 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with topical compositions comprising tapinarof and a pde4 inhibitor |
| GB202000167D0 (en) * | 2020-01-07 | 2020-02-19 | Cytovation As | Composition for treatment of neoplastic lesions |
| US11154486B2 (en) | 2020-02-14 | 2021-10-26 | William M. Yarbrough Foundation | Detergent compositions for washing urushiol and methods of treating urushiol induced contact dermatitis |
| US11191708B2 (en) * | 2020-02-17 | 2021-12-07 | William M. Yarbrough Foundation | Sodium lauroyl sarcosinate containing detergent compositions |
| MX2022015792A (es) * | 2020-06-24 | 2023-02-27 | Dermavant Sciences GmbH | Composiciones farmaceuticas topicas. |
| BR112022027083A2 (pt) * | 2020-06-30 | 2023-03-14 | Dermira Inc | Inibidores de rorgamat e usos tópicos dos mesmos |
| WO2022066803A1 (en) | 2020-09-22 | 2022-03-31 | Alphyn Biologics, Llc | Topical croton lechleri compositions and their use in the treatment of a bacterial colonization or primary or secondary bacterial infection of an underlying skin disorder |
| MX2023005658A (es) * | 2020-11-23 | 2023-09-07 | Dermavant Sciences GmbH | Formulaciones de gel, ungüento y espuma de tapinarof y metodos de uso. |
| CA3208742A1 (en) * | 2021-02-17 | 2022-08-25 | David Scott Rubenstein | Remittive effects of tapinarof in the treatment of plaque psoriasis, atopic dermatitis, or radiation dermatitis |
| CA3209718A1 (en) * | 2021-02-25 | 2022-09-01 | Gary Michael PEKOE | Composition for treatment of topical dermatological bacterial skin conditions |
| CN113797159A (zh) * | 2021-10-22 | 2021-12-17 | 冠昊生物科技股份有限公司 | 一种本维莫德乳膏剂及其制备方法和用途 |
| US20260069553A1 (en) * | 2022-08-30 | 2026-03-12 | Dermavant Sciences GmbH | TAPINAROF AND ANALOGS THEREOF FOR USE IN TREATING AhR MEDIATED DISEASES |
| KR20250120318A (ko) * | 2022-12-08 | 2025-08-08 | 헤어다오 페이먼츠 엘엘씨 | 탈모 및 백발의 치료 및 방지를 위한 외용제 조성물 |
| WO2025031935A1 (en) | 2023-08-04 | 2025-02-13 | Sandoz Ag | Crystalline forms of tapinarof |
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| WO1999059561A2 (en) | 1998-05-18 | 1999-11-25 | Hensley, Kenneth, L. | Resveratrol inhibition of myeloperoxidase |
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| FR2785284B1 (fr) | 1998-11-02 | 2000-12-01 | Galderma Res & Dev | Analogues de la vitamine d |
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| FR2811564B1 (fr) | 2000-07-13 | 2002-12-27 | Oreal | Nanoemulsion contenant des polymeres non ioniques, et ses utilisations notamment dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique |
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