JP2000273033A - Gel comprising natural material - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject gel having salt tolerance, capable of containing an inorganic salt in a high concentration and freely adjusting viscoelasticity thereof to give a high adhesiveness to the skin, capable of containing a functional component and a component with drug action and useful for cosmetic or the like for prevention of skin aging and chapped skin by including carrageenan as a gelling component, a functional component such as tourmaline fine powder and trehalose. SOLUTION: (A) A suitable amount of water is added to carrageenan which is extracted from a seaweed as a gelling component, and (B) an alkali metal ion such as potassium ion or cesium ion is included, and (C) a functional component such as a deep sea water containing a natural mineral component, a functional water made by electrolysis and/or tourmaline fine powder, an oil and fat of plant (ex. borage oil, evening primrose oil, avocado oil, etc.), an alcohol, an extract from plants or bacteria (ex. a Panax ginseng extract, a swertia herb extract, a yeast extract, a bifidobacterium extract, etc.), and (D) trehalose are included.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a natural material gel used for external preparations for skin such as skin hygiene agents and cosmetics, and more particularly, it has excellent feeling of use and smoothness of natural gel, The present invention relates to a natural material gel used for an external preparation for skin and a cosmetic for an aging preventing effect, a skin roughening preventing effect and a moisturizing effect.

[0002]

2. Description of the Related Art Conventionally, cosmetics such as emulsions, creams, lotions, packs, shampoos, rinses, and cleaning agents, and external preparations such as ointments, dispersions, creams, and external preparations have been used. In order to impart a predetermined medicinal effect to these, a medicinal component is compounded, and a gel which is a water-soluble polymer compound is compounded as a thickener, an emulsifier, and a film forming agent. Gels, which are high molecular compounds formulated as thickeners, emulsifiers, film-forming agents, etc., are used, for example, for the purpose of improving the feeling of use such as hair setting agents for hair setting, protective split-coating agents and shampoos, and rinses. Formulated in basic cosmetics such as hair products, hand creams, facial creams, sunscreen creams, makeup cosmetics such as foundations, eye shadows, lipsticks, body cosmetics such as insect repellent lotions and antiperspirant creams, and quasi-drugs It is mainly used for the purpose of maintaining and stabilizing the medicinal effects of external preparations.

[0003] Among water-soluble polymer compounds, various resin-based materials widely used generally as gel products include:
For example, polyvinyl alcohol, polyvinylpyrrolidone, polyvinyl acetate, sodium polyacrylate, polyethyl methacrylate, highly polymerized polyethylene glycol, polyoxyethylene / polyoxypropylene copolymer, acrylic acid / alkyl methacrylate copolymer, carboxy Vinyl polymer, polyethyleneimine, and the like are used as basic components, and there is an excellent aspect that it has transparency and good spreadability. However, since polymers made from acrylic acid and its salts are anionic, gel-like substances are formed by the action of salts such as sodium chloride contained in sweat in the deep sea water or secreted in the deep sea water. There is a property that water separates from the component to be formed, and the viscosity of the gel rapidly decreases, resulting in liquefaction or slime. In other words, the polymer made from acrylic acid and its salts is used by applying it to the skin and hair in the formulation as an external preparation for skin, but after application, it becomes difficult to gel due to the action of salts such as sodium chloride, and it peels off. Not only does the skin lose its absorbability, but the gel dissolves and a film of the residual monomer adheres to the skin surface and hair, forming a skin that impedes skin respiration, impairing the activation of the skin and hair. There are known problems such as hindrance to free expansion and contraction of the skin, resulting in a feeling of tension on the skin, a slight sensation of pain, a poor feeling of use, and soiling of clothes (see, for example, Japanese Unexamined Patent Application Publication No. -110702). Furthermore, since alkali metal salts of polycarboxylic acids have poor affinity for alcohols such as ethanol and isopropanol, there is a known problem that skill is required in the production process to incorporate alcohols (for example, JP-A-9-110702).

[0004] In order to keep the skin healthy and beautiful and activate its physiological functions, it is important to keep the skin clean and to carry out skin care (care) every day. The outer surface of human skin is covered with epidermis, and when the epidermis ages, the stratum corneum peels off and is replaced by new cells. However, if the skin remains dirty, the old keratin accumulates, preventing the formation of new keratin from below, and disrupting the normal metabolism of the skin. Moreover, lipids derived from sebaceous glands and epidermal cells are present on the skin surface, and are oxidized by the action of oxygen and ultraviolet rays in the air to produce lipid peroxide. This lipid peroxide alters the keratinocytes of the epidermis, making them hard and brittle, and promoting skin aging. Therefore, in order to keep the skin clean, regular and thorough skin care is required,
In particular, since the film of the monomer remaining on the face cannot be strongly rubbed off, there is a strong demand for improvement of gels used in skin external preparations and cosmetics.

[0005] In external preparations and cosmetics containing a medicinal component and a functional component, if the amount is sufficient to obtain the effects of the medicinal component and the functional component, the gel lacks stability.
Gels used in external skin preparations and cosmetics, in addition to problems such as impaired usability, as well as the need to adhere to the skin surface so that the medicinal and functional ingredients to be incorporated are efficiently transdermally absorbed Improvement was desired. Further, it has been desired to provide an external preparation which improves the effect of a medicinal ingredient to be incorporated in a skin external preparation and a cosmetic and reduces irritation to the skin.

[0006]

[Means for Solving the Problems] The present inventors have conducted intensive studies to improve the effects of medicinal and functional ingredients, reduce irritation to the skin, and to effect skin hygiene.
By blending trehalose with the natural gelling ingredient carrageenan, which is a natural material, it is stable against heat, its viscosity can be adjusted freely, it has a very smooth shape with rich viscoelasticity, and it has excellent adhesion to the epidermis, so its medicinal properties Improved the transdermal absorption effect of the components, good feeling in use, no browning (Maillard reaction), transparent gel for skin external preparations and cosmetics was found to be obtained from natural materials did. In addition, the present inventors have improved the problems of the prior art, can contain a high concentration of salt tolerance and / or inorganic salt, due to efficient percutaneous absorption, is effective in the treatment of skin diseases and the like, It is possible to freely adjust the viscosity and provide a safe gel that improves the transdermal absorption effect of the medicinal component because of its excellent adhesion to the epidermis, and the provided gel has the inherent action of the medicinal component. Sufficiently exhibited, good feeling in use, as a result of intensive research as it is necessary that various functional components and the like can be blended, it was found that the above object can be achieved by using carrageenan which is a seaweed extract, Deep sea water containing abundant natural minerals, functional water produced by electrolysis and / or tourmaline fine powder, microbial extract, plant extract, or vegetable oil such as borage oil Alternatively it found that it is possible to solve the functionality of remembering problem by appropriately plurality of combinations formulation.

[0007] That is, the present invention is a natural material gel which is provided for skin external preparations and cosmetics comprising carrageenan as a gelling component and trehalose, and further comprises the following components (A) and (B) or ( (B) and (C); (A) a gel obtained by blending trehalose with carrageenan as a gelling component; (B) a functional component; and (C) a gel containing carrageenan as a gelling component. It is a functional natural material gel used for preparations and cosmetics. The details will be described below.

[0008]

DETAILED DESCRIPTION OF THE INVENTION In order to achieve the object of the present invention, a natural raw material gel component uses carrageenan which is a seaweed extract. Carrageenan has a sulfuric acid group in the molecule, so the addition of salts causes the crosslinked structure and the physical properties derived from it to be different.However, it has salt resistance and is classified into ι-, κ- and λ- depending on the sulfate group content of carrageenan. They are distinct and have different gel formation properties. In order to form a gel using carrageenan, an alkali metal ion is generally used, and it is known that potassium and cesium ions act particularly strongly. Since the gel obtained from the natural material carrageenan is resistant to the salt of sweat secreted from the skin, it solves the above problems due to gel dissolution and is effective for skin external preparations and cosmetics. It is possible to mix deep water containing water, functional water produced by electrolysis and / or tourmaline fine powder, vegetable oils and fats such as borage oil, alcohol, plant and bacterial extracts, etc., as external preparations for skin and cosmetics It is possible to provide a functional natural material gel.

Since carrageenan which is a gel component of the seaweed extract used in the present invention is nonionic to weakly anionic, the gel preparation of the present invention is applied and applied on an anionic surface of weakly acidic skin. It is considered that the skin adhesion is higher than that of ionic ones, and even in the presence of water and salt, the polymer chains can maintain cohesive force without expansion and contraction due to the interaction of ions, so that the physical properties of cream strength are reduced. The viscosity of the gel of the present invention can be controlled freely, and the gel of the present invention can be prevented from dissolving and falling off. In addition, since the natural material gel of the present invention is hydrophilic, it absorbs the water secreted on the skin surface, so that the gel maintains the skin adhesion, and the functional components to be blended and the satisfactory pharmacological effects are sufficiently obtained. And
In addition, an equilibrium state is established with water vapor in the outside world, thereby preventing skin unevenness and rash. Further, the gel preparation of the present invention,
The viscosity can be adjusted freely.

Trehalose is a type of disaccharide to which glucose is bound, and is widely distributed in nature in algae, fungi such as mushrooms and shiitake mushrooms, insects, invertebrates, and the like. Is said to act as a blood sugar or antifreeze and is also called "sugar of life". The hypothesis is that under completely dehydrated conditions, trehalose directly hydrogen bonds to cell membranes and protein surfaces and consequently acts as a substitute for bound water.There is a `` water displacement hypothesis, '' which maintains softness, does not cause color burns, and is heat resistant.・ Has acid resistance, suppresses stickiness, and suppresses protein denaturation.

Since trehalose is non-reducing, it does not cause browning (Maillard reaction) even when heated in the presence of amino acids and proteins. Therefore, heating and high-temperature storage during the gel production process, skin external preparations and cosmetics It is known that the quality is very stable even when heating or preserving at high temperature during the production process (for example, JP-A-6-279227). It is the most stable disaccharide to acid and heat among natural disaccharides. It has no coloring or decomposition, has acid resistance and salt resistance, and hardly absorbs or releases moisture up to 95% relative humidity. The natural material gel of the present invention, which is obtained by blending trehalose in the gel manufacturing process, has very stable quality, has no browning, is transparent, solves the problems of the polymer gel, and solves the problems of the polymer gel. This gel is rich in viscoelasticity unlike the gel form of gelatin, and can be used in combination with a known external preparation for skin or a base for cosmetics. It can also be used in the food field.

In recent years, skin treatments such as atopic dermatosis using deep ocean water having a depth of 200 m or less have been considered to be effective (see, for example, JP-A-10-182412).
Publication), deep sea water is a form in which surface seawater has settled to form a layer, and is low-temperature, clean, and rich in nutrient salts, and its intake sea area is 1000 m to 4000 m off Toyama prefecture.
It is preferably 2000 m to 3000 m, and the water intake depth is 250 m to 500 m, preferably 300 m to 400 m. For example, in the sea area of 2500m to 2700m off Toyama Prefecture, deep water sampled from a depth of 300m to 350m has a lower temperature than surface water as shown in Table 1 below.
It was rich in nutrients and clean (see, for example,
0-182412). The content of deep water in the skin preparation for external use and the cosmetic of the present invention is not particularly limited, but is preferably from 0.1 to 85% by weight, more preferably from 5 to 50% by weight.

[0013]

[Table 1]

It is known that the gel of the present invention exerts a therapeutic effect such as atopic dermatitis on carrageenan, which is a component of a natural material gel, without generating allergens (for example, Japanese Patent Application Laid-Open No. Hei 9-110702). A gel containing abundant natural minerals and deep sea water that rarely retains bacteria. When a medicinal component is combined, the action of the medicinal component is sufficiently exhibited (for example, JP-A-10-1824).
No. 12).

The gel of the present invention comprises pure water in an oxidized state,
The purified water is brought into a reduced state using electrolysis and / or tourmaline (fine powder of tourmaline, about 0.300 micron or less), etc., and the surface activity of the water itself is generated by generating hydroxyl ions. It is a gel containing not only functional but also functional water and / or reduced water, which is said to have a physiologically active function due to low reduction potential. This functional water has a pH of 6.8 to 7.6 and its redox unit (ORP)
Is said to be in the state of human body fluid at 250 mv to -200 mv, and contains a large amount of active hydrogen (atomic hydrogen) that can directly decompose and eliminate active enzymes (free radicals) that oxidize the body. It is expected to have physiological activation and anti-aging effects.

Since the functional water in the reduced state is water having a surface activity, the oil dissolves in the water, causes an O / W emulsion emulsification, and has a property of removing oil stains without a detergent. I have. Hydroxyl ions (H ₂ O ₂ ⁻ ) expressing the surface active ability of functional water are:
An ion in which the water molecule H ₂ O is bonded to OH ⁻ ,
OH H portion of Upon hydrophilic group ^- portion becomes hydrophobic group, are believed to have the nature of a small anion surfactant. OH ^- 2 negative charge of the H-OH of
It is thought that this contributes to the bonding between two H and O of the OH group, while the amount of charge of the positive and negative ions in the aqueous solution must be equal according to the "law of electrical neutrality" . The hydroxyl ion in the absence of the control cation is in an energetically unstable state, that is, an activated state, because of the existence contrary to this rule.
Therefore, since hydroxyl ions are unstable in water, they rapidly move to the water interface, and H—O—H
An attempt is made to arrange the moieties of the groups in the water and the H of the OH ^- groups towards the outside of the water. Thus, the hydroxyl ions themselves attempt to stabilize, the result of which acts as a surfactant.

The gel of the present invention can contain various vegetable fatty acids and alcohols. For example, borage oil and / or
Also, it is known that seed oil has an effect of improving the physiological activity of skin tissues and skin cells and moisturizing effect (see, for example, JP-A-9-2).
No. 78641), it is also known that it has an antioxidant effect that strongly suppresses free radicals caused by active enzymes (for example, Japanese Patent Application Laid-Open No. 3-56585). This makes it possible to prevent skin inflammation and eczema, prevent infection, and effectively exhibit skin bioactive effects and aging prevention effects such as moisturizing, improving skin roughness, and preventing skin roughness. Furthermore, alcohols such as ethanol and isopropyl alcohol can be blended at a concentration of about 40%, and ethanol and isopropyl alcohol have a disinfecting and disinfecting effect on the skin surface and can be blended. The effect of prevention is expected.

The alcohol used in the gel of the present invention is limited to the alcohol specified in the cosmetic base. Polyhydric alcohols can be expected to enhance the percutaneous absorption of deep water by increasing the moisturizing properties of the skin.
In particular, propylene glycol has a preservative effect, and glycerin, 1.3-butanediol has an effect of reducing skin irritation of ethanol. In addition, these compounds can be used because they dissolve in aromatic alcohols such as benzyl alcohol and cyclohexanol.

Since the gel of the present invention is water-soluble, it is possible to mix various cosmetic ingredients and medical ingredients as functional ingredients. For example, microorganism-derived extracts (yeast extract, lactic acid bacteria extract, bifidobacterium extract, reishi extract, etc.), plant-derived extracts (panax ginseng extract,
Rosemary extract, assembly extract, oak extract, garlic extract, ginkgo extract, capsicum extract, hinokitiol, cepharanthin, etc.), α-
Or γ-linolenic acid, eicosapentaenoic acid and derivatives thereof, succinic acid and derivatives thereof and salts thereof, estradiol and derivatives thereof, and salts thereof, α-hydroxy acids such as glycolic acid, lactic acid, and salicylic acid and derivatives thereof. And their salts, mucopolysaccharides and their salts (such as hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparan sulfate, heparin and keratan sulfate), proteins such as collagen, elastin, keratin and derivatives thereof, and salts thereof, sorbitol , Inositol, trehalose, urea, pyrrolidonecarboxylic acid and its salt, glycine and its salt or its derivative, serine and its salt or its derivative, arginine and its salt or its derivative, glycerin 1,
Polyhydric alcohols such as 3-butylene glycol, D-panthenol, aloe extract, sicon extract, seaweed extract,
Quince extract, hamamelis extract, chamomile extract,
Ogre extract and Altea extract can be blended as functional components of the gel of the present invention.

In the gel of the present invention, in addition to the above-mentioned essential components, components that are blended into ordinary skin external preparations and cosmetics, for example, oils, powders, surfactants, purified water, higher alcohols, higher fatty acids In addition to humectants, ultraviolet absorbers, ultraviolet scattering agents, antioxidants, pigments, preservatives, fragrances, cosmetic ingredients, and the like, keratin softeners can be appropriately selected and used as long as the effects of the present invention are not impaired. .

The natural material gel of the present invention is prepared according to a conventional method,
It can be adjusted alone or by blending the essential components (A), (B) and (C) with various forms of bases known as ordinary skin preparations and cosmetics.

The functional natural material gel of the present invention expresses its properties more and further processes and
For the purpose of improving the moldability and quality, and the dispersibility and stability of the functional component, additives selected from the pharmaceutically acceptable additives according to the purpose can be further optionally compounded. Such additives include medicines, stabilizers, fillers, lower alcohols, ultraviolet absorbers, fragrances, coloring agents, usability enhancers, preservatives, preservatives, plasticizers, antioxidants, softeners, p
H regulators, deterioration inhibitors and the like. These additives are arbitrarily added within a range that does not affect the properties of the obtained natural material gel.

Examples of the form of the gel are not particularly limited, and include, for example, skin care cosmetics such as milky lotions, creams, lotions, packs, cleaning agents, makeup cosmetics such as lipsticks, foundations, and scalp / hair cosmetics. And skin external preparations such as ointments, dispersions, creams, and external preparations, and cosmetics and cosmetics.

[0024]

EFFECT OF THE INVENTION Since the natural material gel of the present invention can contain salt resistance and / or an inorganic salt at a high concentration, there is no need to worry about the influence of the residual polymer on the skin. It can fully demonstrate the inherent effects of the combined medicinal ingredients, can freely adjust the viscosity, is smooth and rich in viscoelasticity, has excellent adhesion to the skin, has a good feeling in use, and has very high quality It is a stable gel.
For example, skin external preparations and cosmetics in which a cell activator is used in combination with the natural material gel of the present invention as a medicinal component have a stable and excellent skin bioactive effect and skin aging prevention effect. Maintains firmness and luster, and exerts a high suppression effect on wrinkle formation. Skin external preparations and cosmetics that use a moisturizer in combination are effective in preventing and improving the appearance of "dullness" and the like, because they have a stable and excellent skin roughness improving action and moisturizing action. It is. As described above, the gel of the natural material of the present invention is extremely effective in beauty and medical treatment.

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Claims (10)

[Claims] 1. An appropriate amount of water is added to a gelling component carrageenan (Carrageenan) extracted from seaweed,
Add at least one of alkali metal ions, potassium, cesium ions, cross-linking such as tourmaline fine powder,
A natural material gel for use in skin preparations and cosmetics, characterized by containing trehalose. 2. The following components (A) and (B): (A) a gelling component carrageenan (C) extracted from seaweed;
Aqueous preparations and cosmetics, characterized in that an appropriate amount of water is added to arageenan, at least one of alkali metal ions, potassium, cesium ions, and tourmaline fine powder is added, and trehalose is blended. Natural material gel to be provided for. (B) A natural material gel used for an external preparation for skin and a cosmetic, which comprises a functional component. 3. The following components (C) and (B): (C) a gelling component carrageenan (C) extracted from seaweed;
natural material gel which is obtained by adding an appropriate amount of water to arageenan and adding at least one of crosslinking such as alkali metal ions, potassium, cesium ions, and tourmaline fine powder. (B) A natural material gel used for an external preparation for skin and a cosmetic, which comprises a functional component. 4. The natural material gel for use in external preparations for skin and cosmetics according to claim 1, wherein the functional component is deep ocean water. 5. The skin external preparation and cosmetic according to claim 1, wherein the functional component is functional water ionized by electrolysis and / or tourmaline fine powder. Natural gel. 6. The method according to claim 6, wherein the functional ingredient is borage oil (Borago officinalis).
1; Echinacea spp., Rubiaceae, Rubiaceae), evening primrose oil, avocado oil, almond oil, olive oil, wheat germ oil, safflower oil, camellia oil, castor oil, macadamia nut oil, meadowhome oil, cocoa oil, shea butter, mokurou, etc. 6. A natural material gel for use in external preparations for skin and cosmetics according to any one of claims 1 to 5, wherein the natural material gel is one or more selected from vegetable oils and fats. 7. The natural material gel for use in skin preparations and cosmetics according to claim 1, wherein the functional component is a fine powder of tourmaline. 8. The functional component according to claim 1, wherein the functional component is a microorganism-derived extract such as a yeast extract, a lactic acid bacterium extract, a bifidobacterium extract, and a reishi extract. A natural material gel for use in the preparation for external use on the skin and the cosmetic according to the above. 9. The method according to claim 9, wherein the functional ingredient is Panax ginseng extract,
Plant-derived extracts such as rosemary extract, assembly extract, oak extract, garlic extract, ginkgo extract, capsicum extract, aloe extract, hinokitiol, cepharanthin; α- or γ-linolenic acid, eicosapentaene Acid and derivatives thereof, succinic acid and derivatives thereof, salts thereof, estradiol and derivatives thereof, salts thereof, α-hydroxy acids such as glycolic acid, lactic acid, salicylic acid and derivatives thereof, and one selected from salts thereof Or a natural material gel for use in a skin external preparation and a cosmetic according to any one of claims 1 to 8, which is a combination of two or more. 10. The functional component comprises mucopolysaccharides such as hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparan sulfate, heparin and keratan sulfate and their salts, proteins such as collagen, elastin, keratin and derivatives thereof, and their derivatives. Salt, sorbitol, inositol, trehalose, urea, pyrrolidone carboxylic acid and its salt, glycine and its salt or its derivative, serine and its salt or its derivative, arginine and its salt or its derivative, D-panthenol, glycerin 1, Polyhydric alcohols such as 3-butylene glycol, aloe extract,
10. The method according to claim 1, wherein the extract is one or two or more selected from a siconium extract, a seaweed extract, a quince extract, a hamamelis extract, a chamilet extract, a gougy extract, and an Altea extract. A natural material gel for use in any of the skin external preparations and cosmetics according to any one of the above.