JP2000290184A5 - - Google Patents

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Publication number
JP2000290184A5
JP2000290184A5 JP1999095033A JP9503399A JP2000290184A5 JP 2000290184 A5 JP2000290184 A5 JP 2000290184A5 JP 1999095033 A JP1999095033 A JP 1999095033A JP 9503399 A JP9503399 A JP 9503399A JP 2000290184 A5 JP2000290184 A5 JP 2000290184A5
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JP
Japan
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group
substituted
unsubstituted
represented
compound
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Pending
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JP1999095033A
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English (en)
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JP2000290184A (ja
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Priority to JP11095033A priority Critical patent/JP2000290184A/ja
Priority claimed from JP11095033A external-priority patent/JP2000290184A/ja
Publication of JP2000290184A publication Critical patent/JP2000290184A/ja
Publication of JP2000290184A5 publication Critical patent/JP2000290184A5/ja
Pending legal-status Critical Current

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（式中、Ｒ１及びＲ２は、同一または異なって、水素、ヒドロキシルメチル基、メルカプトメチル基、置換もしくは非置換のアルコキシメチル基、置換もしくは非置換のアルキルチオメチル基、置換もしくは非置換のアルケニルオキシメチル基、または置換もしくは非置換のアルケニルチオメチル基を表し、Ｒ３は、アルキル基を表す）で表される化合物（Ｋ２５２ａ誘導体）［以下、一般式（Ｉ）で表される化合物を化合物（Ｉ）という。他の式番号の化合物についても同様である］は、アルツハイマー病などの神経変性疾患の治療に有益な化合物である［Ｊ．Ｍｅｄ．Ｃｈｅｍ．，４０，１８６３−１８６９（１９９７）、特表平６−５０４７３１、ＷＯ９６／１３５０６］。
JP11095033A 1999-04-01 1999-04-01 経鼻投与製剤 Pending JP2000290184A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11095033A JP2000290184A (ja) 1999-04-01 1999-04-01 経鼻投与製剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11095033A JP2000290184A (ja) 1999-04-01 1999-04-01 経鼻投与製剤

Publications (2)

Publication Number Publication Date
JP2000290184A JP2000290184A (ja) 2000-10-17
JP2000290184A5 true JP2000290184A5 (ja) 2006-05-18

Family

ID=14126786

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11095033A Pending JP2000290184A (ja) 1999-04-01 1999-04-01 経鼻投与製剤

Country Status (1)

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JP (1) JP2000290184A (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117645D0 (en) 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
GB8712176D0 (en) * 1987-05-22 1987-06-24 Cosmas Damian Ltd Drug delivery system
JPH07242550A (ja) * 1994-03-02 1995-09-19 Teijin Ltd 二次性副甲状腺機能亢進症治療剤
DK0912184T3 (da) * 1996-06-25 2002-11-25 Cephalon Inc Anvendelse af K-252a-derivat til behandlingen af perifere eller centrale nervelidelser og cytokinoverproduktion

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