JP2000507230A - 望ましくない標的細胞の破壊方法 - Google Patents

望ましくない標的細胞の破壊方法

Info

Publication number
JP2000507230A
JP2000507230A JP9532482A JP53248297A JP2000507230A JP 2000507230 A JP2000507230 A JP 2000507230A JP 9532482 A JP9532482 A JP 9532482A JP 53248297 A JP53248297 A JP 53248297A JP 2000507230 A JP2000507230 A JP 2000507230A
Authority
JP
Japan
Prior art keywords
cells
cell
antibody
immunotoxin
bone marrow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9532482A
Other languages
English (en)
Japanese (ja)
Inventor
フォットスタ，オイスタイン
クヴァールハイム，グンナル
ユール，シーリ
ワン，メン，ユー
エンゲブローテン，オラフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2000507230A publication Critical patent/JP2000507230A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP9532482A 1996-03-13 1997-03-12 望ましくない標的細胞の破壊方法 Pending JP2000507230A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO961031 1996-03-13
NO961031A NO961031D0 (no) 1996-03-13 1996-03-13 Fremgangsmåte til å drepe uönskede målceller
PCT/NO1997/000074 WO1997033611A1 (en) 1996-03-13 1997-03-12 Method of killing target cells in harvested cell populations with one or more immunotoxins

Publications (1)

Publication Number Publication Date
JP2000507230A true JP2000507230A (ja) 2000-06-13

Family

ID=19899150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9532482A Pending JP2000507230A (ja) 1996-03-13 1997-03-12 望ましくない標的細胞の破壊方法

Country Status (18)

Country Link
US (1) US7198787B2 (de)
EP (1) EP0954329B1 (de)
JP (1) JP2000507230A (de)
CN (1) CN1218411A (de)
AT (1) ATE222122T1 (de)
AU (1) AU710184B2 (de)
BR (1) BR9708049A (de)
CA (1) CA2248620A1 (de)
DE (1) DE69714775T2 (de)
HU (1) HUP9901597A3 (de)
IL (1) IL126014A0 (de)
NO (1) NO961031D0 (de)
NZ (1) NZ331763A (de)
PL (1) PL328804A1 (de)
RU (1) RU2182493C2 (de)
SK (1) SK125798A3 (de)
TR (1) TR199801795T2 (de)
WO (1) WO1997033611A1 (de)

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US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
EP2589668A1 (de) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
CA3069082C (en) 2008-09-20 2022-03-22 The Board Of Trustees Of The Leland Stanford Junior University Noninvasive diagnosis of fetal aneuploidy by sequencing
US8524669B2 (en) 2008-10-17 2013-09-03 Dana-Farber Cancer Institute, Inc. MUC-1 cytoplasmic domain peptides as inhibitors of cancer
AU2010253834B2 (en) 2009-05-27 2013-12-19 Dana-Farber Cancer Institute, Inc. Inhibition 0f inflammation using antagonists of MUC1
CN102127148B (zh) * 2010-01-14 2013-04-03 中国农业科学院北京畜牧兽医研究所 血管内皮细胞表面决定簇部分多肽及其应用
SG194787A1 (en) * 2011-05-06 2013-12-30 Us Gov Health & Human Serv Recombinant immunotoxin targeting mesothelin
CN107748256B (zh) * 2017-10-11 2020-04-14 厦门骁科码生物科技有限公司 一种循环肿瘤细胞的液体活检检测方法

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Also Published As

Publication number Publication date
CA2248620A1 (en) 1997-09-18
ATE222122T1 (de) 2002-08-15
US7198787B2 (en) 2007-04-03
BR9708049A (pt) 1999-07-27
AU2522997A (en) 1997-10-01
US20020151689A1 (en) 2002-10-17
AU710184B2 (en) 1999-09-16
CN1218411A (zh) 1999-06-02
HUP9901597A2 (hu) 1999-08-30
DE69714775T2 (de) 2003-04-24
HUP9901597A3 (en) 2000-06-28
TR199801795T2 (xx) 1998-12-21
NZ331763A (en) 2000-01-28
DE69714775D1 (de) 2002-09-19
WO1997033611A1 (en) 1997-09-18
IL126014A0 (en) 1999-05-09
PL328804A1 (en) 1999-02-15
EP0954329A1 (de) 1999-11-10
EP0954329B1 (de) 2002-08-14
SK125798A3 (en) 1999-05-07
RU2182493C2 (ru) 2002-05-20
NO961031D0 (no) 1996-03-13

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