JP2001504331A5 - - Google Patents

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Publication number
JP2001504331A5
JP2001504331A5 JP1998521150A JP52115098A JP2001504331A5 JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5 JP 1998521150 A JP1998521150 A JP 1998521150A JP 52115098 A JP52115098 A JP 52115098A JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998521150A
Other languages
English (en)
Japanese (ja)
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JP2001504331A (ja
JP4339406B2 (ja
Filing date
Publication date
Priority claimed from GBGB9623236.8A external-priority patent/GB9623236D0/en
Priority claimed from GBGB9715674.9A external-priority patent/GB9715674D0/en
Priority claimed from GBGB9719350.2A external-priority patent/GB9719350D0/en
Application filed filed Critical
Priority claimed from PCT/GB1997/003058 external-priority patent/WO1998020142A1/en
Publication of JP2001504331A publication Critical patent/JP2001504331A/ja
Publication of JP2001504331A5 publication Critical patent/JP2001504331A5/ja
Application granted granted Critical
Publication of JP4339406B2 publication Critical patent/JP4339406B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP52115098A 1996-11-07 1997-11-06 免疫療法に使用する医薬の製造におけるＳｅｒｒａｔｅまたはＤｅｌｔａの使用 Expired - Fee Related JP4339406B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9623236.8 1996-11-07
GBGB9623236.8A GB9623236D0 (en) 1996-11-07 1996-11-07 Notch
GB9715674.9 1997-07-24
GBGB9715674.9A GB9715674D0 (en) 1997-07-24 1997-07-24 Notch
GB9719350.2 1997-09-11
GBGB9719350.2A GB9719350D0 (en) 1997-09-11 1997-09-11 Notch
PCT/GB1997/003058 WO1998020142A1 (en) 1996-11-07 1997-11-06 Notch

Publications (3)

Publication Number Publication Date
JP2001504331A JP2001504331A (ja) 2001-04-03
JP2001504331A5 true JP2001504331A5 (2) 2005-05-12
JP4339406B2 JP4339406B2 (ja) 2009-10-07

Family

ID=27268574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52115098A Expired - Fee Related JP4339406B2 (ja) 1996-11-07 1997-11-06 免疫療法に使用する医薬の製造におけるＳｅｒｒａｔｅまたはＤｅｌｔａの使用

Country Status (20)

Country Link
EP (2) EP0942998B1 (2)
JP (1) JP4339406B2 (2)
KR (1) KR100393234B1 (2)
CN (2) CN1160371C (2)
AT (1) ATE299184T1 (2)
AU (1) AU736361B2 (2)
BG (1) BG103444A (2)
CA (1) CA2271248C (2)
CZ (1) CZ295997B6 (2)
DE (1) DE69733695T2 (2)
ES (1) ES2243986T3 (2)
GB (2) GB2335194B (2)
GE (1) GEP20043390B (2)
IL (1) IL129531A0 (2)
NO (1) NO992196L (2)
NZ (1) NZ335549A (2)
PL (1) PL333302A1 (2)
RO (1) RO120850B1 (2)
TR (1) TR199901000T2 (2)
WO (1) WO1998020142A1 (2)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861261B9 (en) 1995-06-28 2010-02-24 Imperial Cancer Research Technology Limited Nucleotide and protein sequences of vertebrate delta genes and methods based thereon
US5780300A (en) * 1995-09-29 1998-07-14 Yale University Manipulation of non-terminally differentiated cells using the notch pathway
GB9824045D0 (en) * 1998-11-03 1998-12-30 European Molecular Biology Lab Embl Regulator protein
GB9827604D0 (en) * 1998-12-15 1999-02-10 Lorantis Ltd Methods of immunosuppression
GB9927328D0 (en) 1999-11-18 2000-01-12 Lorantis Ltd Immunotherapy
GB0019242D0 (en) * 2000-08-04 2000-09-27 Lorantis Ltd Assay
US6689744B2 (en) 2000-09-22 2004-02-10 Genentech, Inc. Notch receptor agonists and uses
JP4365583B2 (ja) * 2000-09-22 2009-11-18 ジェネンテック・インコーポレーテッド ノッチレセプターアゴニスト及び用途
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
GB0118155D0 (en) * 2001-07-25 2001-09-19 Lorantis Ltd Superantigen
WO2003011317A1 (en) * 2001-07-25 2003-02-13 Lorantis Limited Modulators of notch signalling for use in immunotherapy
GB0123379D0 (en) * 2001-09-28 2001-11-21 Lorantis Ltd Modulators
DK1479767T3 (da) * 2002-02-06 2013-11-25 Sanbio Inc Fremgangsmåde til differentiering/inducering af stromaceller fra knoglemarv til nerveceller ved overføring af Notch-gen
JP2006506322A (ja) * 2002-04-05 2006-02-23 ロランティス リミテッド 内科療法
WO2004013179A1 (en) * 2002-08-03 2004-02-12 Lorantis Limited Conjugate of notch signalling pathway modulators and their use in medical treatment
GB0218879D0 (en) * 2002-08-14 2002-09-25 Lorantis Ltd Medical treatment
GB0220658D0 (en) * 2002-09-05 2002-10-16 Lorantis Ltd Immunotherapy
WO2004032969A1 (en) * 2002-10-09 2004-04-22 Lorantis Limited Modulation of immune function
WO2004060262A2 (en) * 2003-01-07 2004-07-22 Lorantis Limited Modulators of notch signalling for use in immunotherpapy
GB0300428D0 (en) * 2003-01-09 2003-02-05 Lorantis Ltd Medical treatment
JP2006517533A (ja) * 2003-01-23 2006-07-27 ロランティス リミテッド Ｎｏｔｃｈシグナル伝達経路のアクチベーターを用いる自己免疫疾患の治療
GB0303663D0 (en) * 2003-02-18 2003-03-19 Lorantis Ltd Assays and medical treatments
ATE474593T1 (de) * 2003-03-21 2010-08-15 Celldex Therapeutics Ltd Behandlung von allergischen erkrankungen unter verwendung eines modulators des notch signaling pathway
WO2004083372A2 (en) * 2003-03-21 2004-09-30 Lorantis Limited Modulators of the notch signaling pathway immobilized on particles for modifying immune responses
GB0307472D0 (en) * 2003-04-01 2003-05-07 Lorantis Ltd Medical treatment
US7919092B2 (en) 2006-06-13 2011-04-05 Oncomed Pharmaceuticals, Inc. Antibodies to notch receptors
EP2125887A4 (en) 2007-01-24 2010-11-10 Oncomed Pharm Inc COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
CN104402998A (zh) 2008-07-08 2015-03-11 昂考梅德药品有限公司 分离的抗体
JP2012500791A (ja) * 2008-08-22 2012-01-12 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｎｏｔｃｈ３シグナル伝達のデコイインヒビターとしてのヒトｎｏｔｃｈ３に基づく融合タンパク質
US8709710B2 (en) 2009-02-16 2014-04-29 Deutsches Rheuma-Forschungszentrum Berlin Methods of modulating interleukin-22 and immune response by notch regulators
WO2011025964A2 (en) 2009-08-29 2011-03-03 Abbott Laboratories Therapeutic dll4 binding proteins
BR112012021941A2 (pt) 2010-03-02 2022-02-01 Abbvie Inc Proteínas terapêuticas de ligação a dll4
EP2694080B1 (en) * 2011-04-06 2018-03-14 SanBio, Inc. Methods and compositions for modulating peripheral immune function
EP2780354A4 (en) * 2011-11-16 2015-06-24 Oncomed Pharm Inc HUMAN NOTCH RECEPTOR MUTATIONS AND THEIR USE
US20150140043A1 (en) * 2012-05-10 2015-05-21 Institut National De La Sante De La Recherche Medical (Inserm) Immunomodulatory methods using notch agonists
KR101573650B1 (ko) * 2015-02-04 2015-12-01 성균관대학교산학협력단 Hcmv 바이러스 복제 억제용 조성물
BR112021003830A2 (pt) * 2018-08-28 2021-07-20 Fred Hutchinson Cancer Research Center métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101728A (en) * 1991-05-03 2007-08-19 Univ Yale Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them
US5869282A (en) * 1991-12-11 1999-02-09 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of the serrate gene and methods based thereon
US5786158A (en) * 1992-04-30 1998-07-28 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
CA2182498A1 (en) * 1994-02-01 1995-08-10 William J. Larochelle Fusion proteins that include antibody and nonantibody portions
US5780300A (en) * 1995-09-29 1998-07-14 Yale University Manipulation of non-terminally differentiated cells using the notch pathway
DE69635899T2 (de) * 1995-11-17 2006-11-23 Asahi Kasei Kabushiki Kaisha Polypeptid, das die differenzierung unterdrueckt

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