JP2001521737A - 回転瓶内の水痘感染細胞培養物の混合増進方法 - Google Patents

回転瓶内の水痘感染細胞培養物の混合増進方法

Info

Publication number
JP2001521737A
JP2001521737A JP2000519066A JP2000519066A JP2001521737A JP 2001521737 A JP2001521737 A JP 2001521737A JP 2000519066 A JP2000519066 A JP 2000519066A JP 2000519066 A JP2000519066 A JP 2000519066A JP 2001521737 A JP2001521737 A JP 2001521737A
Authority
JP
Japan
Prior art keywords
bottle
flow
particles
mixing
rotating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000519066A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001521737A5 (de
Inventor
ブランブル，ジヨーイ・エル
サーレス，ジエイムズ・エイ
ムツツイオ，フエルナンド・ジエイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727130.8A external-priority patent/GB9727130D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JP2001521737A publication Critical patent/JP2001521737A/ja
Publication of JP2001521737A5 publication Critical patent/JP2001521737A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • C12M27/12—Roller bottles; Roller tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting

Landscapes

  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2000519066A 1997-10-31 1998-10-27 回転瓶内の水痘感染細胞培養物の混合増進方法 Pending JP2001521737A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US6444897P 1997-10-31 1997-10-31
US6726497P 1997-12-03 1997-12-03
GB9727130.8 1997-12-22
GB60/067,264 1997-12-22
GBGB9727130.8A GB9727130D0 (en) 1997-12-22 1997-12-22 A method of improved mixing of a varicella-infected cell culture in roller bottles
GB60/064,448 1997-12-22
PCT/US1998/022716 WO1999023206A1 (en) 1997-10-31 1998-10-27 A method of improved mixing of a varicella-infected cell culture in roller bottles

Publications (2)

Publication Number Publication Date
JP2001521737A true JP2001521737A (ja) 2001-11-13
JP2001521737A5 JP2001521737A5 (de) 2006-01-05

Family

ID=27269149

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000519066A Pending JP2001521737A (ja) 1997-10-31 1998-10-27 回転瓶内の水痘感染細胞培養物の混合増進方法

Country Status (5)

Country Link
EP (1) EP1027426A4 (de)
JP (1) JP2001521737A (de)
AU (1) AU742756B2 (de)
CA (1) CA2307832C (de)
WO (1) WO1999023206A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2295465T3 (es) 2002-09-16 2008-04-16 Pan-Biotech Gmbh Procedimiento para el cultivo de celulas, en especial de celulas humanas o de animales.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5780326A (en) * 1980-09-11 1982-05-19 Merck & Co Inc Simple herpes i type subunit vaccine
JPS61138522A (ja) * 1984-12-11 1986-06-26 Matsushita Electric Ind Co Ltd 混合機
JPH06181750A (ja) * 1992-09-02 1994-07-05 Heraeus Sepatech Gmbh 培養容器
JPH0851974A (ja) * 1994-07-14 1996-02-27 Akzo Nobel Nv マレック病ウイルスワクチン
WO1997037001A1 (en) * 1996-04-01 1997-10-09 Chiron Behring Gmbh & Co. Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3893887A (en) * 1973-07-09 1975-07-08 Univ Duke Method for rapid harvesting of roller culture supernatant fluid
US3982259A (en) * 1974-12-13 1976-09-21 Edward Van Baerle Photographic material processing module
US4000256A (en) * 1975-04-30 1976-12-28 Merck & Co., Inc. Varicella vaccine and process for its preparation
DE2934328C2 (de) * 1979-08-24 1982-04-29 Stephan Dipl.-Chem. Dr.rer.nat. 8000 München Nees Verfahren zur Kultivierung matrixgebundener biologischer Zellsysteme sowie Vorrichtung zur Ausübung des Verfahrens
US4307965A (en) * 1980-05-30 1981-12-29 Innovative Medical Systems Corp. Mixing apparatus
US4686101A (en) * 1985-08-02 1987-08-11 Merck & Co., Inc. Vaccine against varicella-zoster virus
DE3780044D1 (de) * 1986-03-14 1992-08-06 Forschungszentrum Juelich Gmbh Verfahren zur durchfuehrung gasbildender biotechnologischer prozesse in festbettreaktoren und zum be- und entgasen geeignete vorrichtungen.
US5026650A (en) * 1988-06-30 1991-06-25 The United States Of Amercia As Represented By The Administrator Of The National Aeronautics And Space Administration Horizontally rotated cell culture system with a coaxial tubular oxygenator
JPH0568533A (ja) * 1991-09-12 1993-03-23 Hitachi Ltd 生物細胞の培養方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5780326A (en) * 1980-09-11 1982-05-19 Merck & Co Inc Simple herpes i type subunit vaccine
JPS61138522A (ja) * 1984-12-11 1986-06-26 Matsushita Electric Ind Co Ltd 混合機
JPH06181750A (ja) * 1992-09-02 1994-07-05 Heraeus Sepatech Gmbh 培養容器
JPH0851974A (ja) * 1994-07-14 1996-02-27 Akzo Nobel Nv マレック病ウイルスワクチン
WO1997037001A1 (en) * 1996-04-01 1997-10-09 Chiron Behring Gmbh & Co. Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process

Also Published As

Publication number Publication date
EP1027426A1 (de) 2000-08-16
EP1027426A4 (de) 2006-04-19
CA2307832C (en) 2005-09-06
AU1280499A (en) 1999-05-24
WO1999023206A1 (en) 1999-05-14
AU742756B2 (en) 2002-01-10
CA2307832A1 (en) 1999-05-14

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