JP2005507635A5 - - Google Patents

Download PDF

Info

Publication number
JP2005507635A5
JP2005507635A5 JP2002564963A JP2002564963A JP2005507635A5 JP 2005507635 A5 JP2005507635 A5 JP 2005507635A5 JP 2002564963 A JP2002564963 A JP 2002564963A JP 2002564963 A JP2002564963 A JP 2002564963A JP 2005507635 A5 JP2005507635 A5 JP 2005507635A5
Authority
JP
Japan
Prior art keywords
antibody
human
antigen
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002564963A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005507635A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/004024 external-priority patent/WO2002064634A2/en
Publication of JP2005507635A publication Critical patent/JP2005507635A/ja
Publication of JP2005507635A5 publication Critical patent/JP2005507635A5/ja
Pending legal-status Critical Current

Links

JP2002564963A 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体 Pending JP2005507635A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26807501P 2001-02-12 2001-02-12
US33895601P 2001-11-05 2001-11-05
PCT/US2002/004024 WO2002064634A2 (en) 2001-02-12 2002-02-11 Human monoclonal antibodies to fc alpha receptor (cd89)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009187733A Division JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Publications (2)

Publication Number Publication Date
JP2005507635A JP2005507635A (ja) 2005-03-24
JP2005507635A5 true JP2005507635A5 (2) 2005-12-22

Family

ID=26952868

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002564963A Pending JP2005507635A (ja) 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体
JP2009187733A Withdrawn JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009187733A Withdrawn JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Country Status (12)

Country Link
US (1) US7192582B2 (2)
EP (1) EP1370588A2 (2)
JP (2) JP2005507635A (2)
KR (1) KR100890088B1 (2)
CN (1) CN1312181C (2)
AU (1) AU2002240338C1 (2)
CA (1) CA2437814C (2)
IL (2) IL157274A0 (2)
MX (1) MXPA03007144A (2)
NZ (1) NZ527977A (2)
WO (1) WO2002064634A2 (2)
ZA (1) ZA200305996B (2)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192584B2 (en) * 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
CA2441228A1 (en) * 2001-03-23 2002-10-03 Aphton Corporation Combination treatment of pancreatic cancer
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
US20030021786A1 (en) * 2001-07-09 2003-01-30 Gevas Philip C. Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
US20060165675A1 (en) * 2002-08-02 2006-07-27 Richman-Eisenstat Janice Beth Modulation of mesenchymal cells via iga-receptors
US20060020119A1 (en) * 2004-03-29 2006-01-26 Stephen Grimes Monoclonal antibodies to gastrin hormone
WO2004088326A2 (en) * 2003-03-28 2004-10-14 Aphton Corporation Gastrin hormone immunoassays
AR045563A1 (es) 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
EP1570858A1 (en) 2004-03-05 2005-09-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Monovalent ligand of the FCalphaRi receptor as an anti-inflammatory agent
DK1794586T3 (da) * 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
PL1874821T3 (pl) 2005-04-26 2013-09-30 Trion Pharma Gmbh Kombinacja przeciwciał i glikokortykoidów do leczenia raka
RU2423381C2 (ru) 2005-07-25 2011-07-10 Трабьон Фармасьютикалз, Инк. Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
NZ573646A (en) 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
EP2184608B1 (en) * 2007-08-23 2016-10-05 LSI Medience Corporation Non-specific reaction inhibitor
RU2531754C2 (ru) 2008-04-11 2014-10-27 ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством
EP2127666A1 (en) * 2008-05-28 2009-12-02 Drug Discovery Factory B.V. Method for the treatment or prophylaxis of chronic inflammatory diseases
US20130195840A1 (en) * 2010-01-13 2013-08-01 Robert P. Kimberly Therapeutics and processes for treatment of immune disorders
EA201690310A1 (ru) 2010-04-13 2016-12-30 Селлдекс Терапьютикс Инк. Антитела, связывающие cd27 человека, и их применение
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
EP2603520A4 (en) 2010-08-10 2014-02-19 Ecole Polytech ERYTHROCYTE BINDING THERAPEUTICS
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
TW201302793A (zh) 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
EP2465536A1 (en) * 2010-12-14 2012-06-20 CSL Behring AG CD89 activation in therapy
EP3575794A1 (en) * 2012-02-10 2019-12-04 Seattle Genetics, Inc. Detection and treatment of cd30+ cancers
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
BR112014022240A2 (pt) 2012-03-09 2017-08-01 Csl Behring Ag composições compreendendo imunoglobulinas semelhantes à secretoras
EP2636681A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Process for enriching IgA
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
SG11201606761RA (en) 2014-02-21 2016-09-29 Ecole Polytecnique Federale De Lausanne Epfl Epfl Tto Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
CN107428840A (zh) * 2015-03-25 2017-12-01 弗劳恩霍夫应用研究促进协会 抗cd89细胞毒素的复合物
UY36751A (es) 2015-06-26 2017-01-31 Novartis Ag Anticuerpos de factor xi y métodos de uso
WO2017053469A2 (en) 2015-09-21 2017-03-30 Aptevo Research And Development Llc Cd3 binding polypeptides
TW201802121A (zh) 2016-05-25 2018-01-16 諾華公司 抗因子XI/XIa抗體之逆轉結合劑及其用途
EP3904880A1 (fr) * 2016-09-30 2021-11-03 Centre national de la recherche scientifique Marqueurs membranaires
US12188935B2 (en) 2016-09-30 2025-01-07 Centre National De La Recherche Scientifique Method for the evaluation of antiretroviral therapy (ART) effectiveness in HIV-1 CD4+CD89+ cellular reservoirs
WO2018106945A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
AU2017383232B2 (en) 2016-12-23 2024-09-12 Novartis Ag Factor XI antibodies and methods of use
WO2018183929A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
EP3624841A4 (en) 2017-06-15 2021-01-27 Cancer Advances, Inc., COMPOSITIONS AND METHODS OF INDUCING HUMORAL AND CELLULAR IMMUNITIES AGAINST TUMORS AND CANCER
WO2018232176A1 (en) 2017-06-16 2018-12-20 The University Of Chicago Compositions and methods for inducing immune tolerance
AR112257A1 (es) 2017-06-21 2019-10-09 Gilead Sciences Inc Anticuerpos multiespecíficos dirigidos al vih-1 gp120 y cd3 humana, composiciones que los comprende, ácido nucleico, vector y célula huésped relacionados, método para producirlos, método para detectar células que expresan gp120 y cd3, kit de anticuerpos, fragmentos de anticuerpo que se une a gp120 y método para producirlos
CA3097369A1 (en) 2018-04-17 2019-10-24 Celldex Therapeutics, Inc. Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
EP3790577A4 (en) 2018-05-09 2022-04-27 The University of Chicago COMPOSITIONS AND METHODS RELATED TO IMMUNTOLERANCE
WO2019246317A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease or condition in a tissue originating from the endoderm
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
EP3883635A1 (en) 2018-11-19 2021-09-29 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
KR20230004739A (ko) * 2020-04-21 2023-01-06 제이제이피 바이오로직스 에스피. 제트 오.오. 인간화 항-인간 cd89 항체 및 이의 용도
CN116368154A (zh) 2020-10-08 2023-06-30 阿菲姆德股份有限公司 三特异性结合剂
WO2022098084A1 (ko) * 2020-11-06 2022-05-12 고려대학교 산학협력단 Fc 알파 수용체 결합 항체
KR102766045B1 (ko) * 2020-11-06 2025-02-10 고려대학교 산학협력단 Fc 알파 수용체 결합력이 향상된 항체
KR102855679B1 (ko) * 2020-11-06 2025-09-04 고려대학교 산학협력단 Fc 알파 수용체 결합 항체
KR102853685B1 (ko) * 2020-11-06 2025-09-01 고려대학교 산학협력단 Fc 알파 수용체 결합력이 증진된 항체
CA3216098A1 (en) 2021-07-30 2023-02-02 Uwe Reusch Duplexbodies
WO2024218512A1 (en) 2023-04-19 2024-10-24 Centessa Pharmaceuticals (Uk) Limited Activatable bispecific anti-cd89 and anti-pd-l1 proteins and uses thereof
CN117890576A (zh) * 2023-12-12 2024-04-16 深圳市陆为生物技术有限公司 一种检测CD89-IgA免疫复合物的试剂、方法及其应用
WO2025218725A1 (zh) * 2024-04-18 2025-10-23 徕特康(苏州)生物制药有限公司 靶向cd20和cd89的髓细胞衔接子抗体及其用途
WO2026002175A1 (zh) * 2024-06-27 2026-01-02 无锡徕特康生物科技有限公司 靶向ilt7和cd89的髓细胞衔接子抗体及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0496818T3 (da) 1989-10-20 1999-11-22 Dartmouth College IgA-receptor-specifikt monoklonalt antistof
US6018031A (en) * 1989-10-20 2000-01-25 Trustees Of Dartmouth College Binding agents specific for IgA receptor
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5198342A (en) * 1990-07-05 1993-03-30 Immunex Corporation DNA encoding IgA Fc receptors
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
JPH08509612A (ja) 1993-04-26 1996-10-15 ジェンファーム インターナショナル インコーポレイテッド 異種抗体を産生することができるトランスジェニック非ヒト動物
US5922845A (en) * 1996-07-11 1999-07-13 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
EP1212366B1 (en) 1999-07-30 2007-09-12 Medarex, Inc. Therapeutic compounds comprised of anti-fc receptor binding agents
KR100881471B1 (ko) 2000-05-08 2009-02-05 셀덱스 쎄라퓨틱스, 인크. 수상세포에 대한 인간 모노클로날 항체

Similar Documents

Publication Publication Date Title
JP2005507635A5 (2)
US20260115310A1 (en) Compositions and methods for making antibody conjugates
US20230295340A1 (en) Muc1* antibodies
US20250145718A1 (en) Anti-pd-l1/anti-4-1bb bispecific antibodies and uses thereof
IL157274A (en) 89CD monoclonal antibodies of human origin, their segments that bind to antigens, hybridomas and transpectomas that produce them, transgenic cells that express them, couplings of biospecific and multispecific molecules, immunotoxins and preparations containing them, methods for their production and methods for detection
JP7461950B2 (ja) Cd3抗体およびその医薬用途
CN102459346B (zh) 制造异源多聚体分子的方法
JP6273219B2 (ja) 天然の免疫グロブリン形式を有する容易に単離される二重特異性抗体
JP2003516718A5 (2)
CA2892059C (en) Bispecific antibody
CN112851808B (zh) Igf-1r抗体及其作为定位载体用于治疗癌症的用途
TWI854953B (zh) 抗cd3抗體及含有該抗體的分子、及其製造方法
RU2013142600A (ru) Белки, связывающие специфический мембранный антиген простаты, и соответствующие композиции и способы
CN112969476B (zh) 多特异性蛋白分子
JP2018509907A5 (2)
SI2511301T1 (en) Human antibodies to ERBB 2
JP2009297037A5 (2)
US20230080842A1 (en) Tetravalent symmetric bispecific antibodies
RU2017134592A (ru) Антитела к muc16 и их применение
JP2008520186A (ja) 哺乳類eag1イオンチャネルタンパク質に対する新規の抗体
ME02842B (me) Potpuno ljudska antitijela specifična za cadm1
WO2021097800A1 (en) Anti-pd-l1/anti-b7-h3 multispecific antibodies and uses thereof
WO2024175093A1 (en) Antibodies, antigen-binding fragments and methods of use
WO2022166876A1 (zh) 特异性识别磷脂酰肌醇蛋白聚糖3的单克隆抗体及其应用
JP2022549504A5 (2)